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JoVE Journal Neuroscience
HSV-Mediated Transgene Expressie van Chimere constructen tot Behavioral functie van GPCR heteromeren in Muizen Studie
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HSV-Mediated Transgene Expressie van Chimere constructen tot Behavioral functie van GPCR heteromeren in Muizen Studie

Article DOI: 10.3791/53717-v • 07:30 min • July 9th, 2016
July 9th, 2016 •
1, 1, 1,2,3,4
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 2Department of Neurology, Icahn School of Medicine at Mount Sinai, 3Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 4Department of Physiology and Biophysics, Virginia Commonwealth University Medical School

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In dit artikel wordt beschreven hoe u virale vectoren te injecteren in de muis frontale cortex gedragsproblemen assays die GPCR heteromere vorming nodig te testen.

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Neuroscience virus-gemedieerde genoverdracht G-eiwit gekoppelde receptor (GPCR) heteromeer lyserginezuurdiethylamide (LSD) (±) -1- (2,5-dimethoxy-4-joodfenyl) -2-aminopropaan hydrochloride (DOI) hallucinogenen schizofrenie hoofd-twitch response (HTR).
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