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JoVE Journal Neuroscience
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Ved hjælp af en mikrofluidik anordning for mekanisk Stimulation og høj opløsning Imaging af C. elegans

Article DOI: 10.3791/56530-v • 10:39 min • February 19th, 2018
February 19th, 2018 •
*1, *1,2, 1,2, 1,2,3, 1,2, 4
1Department of Molecular and Cellular Physiology, Stanford University, 2Department of Mechanical Engineering, Stanford University, 3Department of Bioengineering, Stanford University, 4Group of Neurophotonics and Mechanical Systems Biology, The Institute of Photonic Sciences (ICFO)
* These authors contributed equally

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Nye værktøjer til mechanobiology forskning er nødvendig for at forstå hvordan mekanisk stress aktiveres biokemiske veje og fremkalder biologiske svar. Her, fremvise vi en ny metode til selektiv mekaniske stimulation af immobiliserede dyr med en mikrofluid fælde så høj opløsning billeddannelse af cellulære svar.

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Neurovidenskab sag 132 mikrofluidik soft-litografi C. elegans mechanobiology mechanosensation calcium dynamics
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