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JoVE Journal Cancer Research
In Vivo EPR bedömning av pH, pO2, Redox Status, och koncentrationer av fosfat och glutation i den tumör mikromiljö
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In Vivo EPR bedömning av pH, pO2, Redox Status, och koncentrationer av fosfat och glutation i den tumör mikromiljö

Article DOI: 10.3791/56624-v • 10:46 min • March 16th, 2018
March 16th, 2018 •
1,2, 1,3, 1,2, 1,2
1In Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, 2Department of Biochemistry, West Virginia University School of Medicine, 3Department of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine

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Låg-fältet (L-band, 1,2 GHz) elektron paramagnetiska resonans med lösliga nitroxyl och trityl sonder demonstreras för bedömning av fysiologiskt viktiga parametrar i den tumör närmiljön i musmodeller av bröstcancer.

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Cancerforskning fråga 133 Electron paramagnetiska resonans nitroxide trityl radikala pH syrekoncentrationen redox status glutation oorganiskt fosfat tumör mikromiljö
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