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Journal / Medicine / Induktion og fænotyping af akut højre hjertesvigt …
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JoVE Journal Medicine
Induktion og fænotyping af akut højre hjertesvigt i en stor dyremodel af kronisk tromboembolic Pulmonal Hypertension
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Induktion og fænotyping af akut højre hjertesvigt i en stor dyremodel af kronisk tromboembolic Pulmonal Hypertension

Article DOI: 10.3791/58057-v • 07:41 min • March 17th, 2022
March 17th, 2022 •
1, 1,2, 1, 1, 3, 4, 5, 1, 1, 2, 1
1Research and Innovation Unit, RHU BioArt Lung 2020, Marie Lannelongue Hospital, 2Phenotypic and Biomarker Core Laboratory, Cardiovascular Institute, Stanford University, 3Department of pathology, Marie Lannelongue Hospital, 4Department of pathology, UCSF School of Medicine, 5Department of thoracic surgery, Hopital Nord, APHM, Aix-Marseille University

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Vi præsenterer en protokol til at fremkalde og fænotype en akut højre hjertesvigt i en stor dyremodel med kronisk lunge hypertension. Denne model kan bruges til at teste terapeutiske interventioner, til at udvikle rigtige hjerte målinger eller til at forbedre forståelsen af akut højre hjertesvigt patofysiologi.

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Medicin Udgave 181 Akut højre hjertesvigt lungehypertension højre ventrikel dyremodel trykvolumensløjfer ekkokardiografi myokardie iskæmi
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