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JoVE Journal Chemistry
Technisch aspect van de geautomatiseerde synthese en real-time kinetische evaluatie van [11C] SNAP-7941
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Technisch aspect van de geautomatiseerde synthese en real-time kinetische evaluatie van [11C] SNAP-7941

Article DOI: 10.3791/59557-v • 09:50 min • April 28th, 2019
April 28th, 2019 •
1, 1, 1, 1,2, 1, 1,3, 1,4, 1
1Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, 2Department for Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, 3Ludwig Boltzmann Institute Applied Diagnostics, 4CBmed GmbH - Center for Biomarker Research in Medicine

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Hier vertegenwoordigen we een protocol voor de volautomatische radioactieve labeling van [11C] SNAP-7941 en de analyse van de real-time kinetiek van deze pet-Tracer op P-GP die cellen uitdrukt en niet uitdrukt.

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Chemie radio synthese PET LigandTracer MCHR1 SNAP-7941 P-glycoproteïne Carbon-11
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