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JoVE Journal
Genetics

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陶子细胞定位作为研究疾病相关基因表达的工具的调制
 
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陶子细胞定位作为研究疾病相关基因表达的工具的调制

Article DOI: 10.3791/59988-v 09:12 min December 20th, 2019
December 20th, 2019

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

Tau 是一种神经元蛋白,存在于细胞质中,它结合微管,在细胞核中,它发挥非常规功能,包括与阿尔茨海默氏病相关基因的调制。在这里,我们描述了一种研究核Tau功能的方法,同时排除了来自细胞质陶的任何干扰。

Tags

遗传学, 问题 154, 核 Tau, 分化 SH-SY5Y, 核分数, 定位信号, 亚细胞分馏, 西污点
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