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Journal / Immunology and Infection / Visão mecanicista do desenvolvimento da fibrose…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Visão mecanicista do desenvolvimento da fibrose intestinal mediada por TNBS e avaliação dos efeitos inibitórios da rapamicina
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Visão mecanicista do desenvolvimento da fibrose intestinal mediada por TNBS e avaliação dos efeitos inibitórios da rapamicina

Article DOI: 10.3791/60067-v • 10:21 min • September 12th, 2019
September 12th, 2019 •
1,2,3, 4, 4, 4, 1,2
1Department of Molecular and Cellular Physiology, Albany Medical College, 2The IBD Center, Division of Gastroenterology, Department of Medicine, Albany Medical College, 3Department of Geriatrics, School of Medicine and Health Science, University of North Dakota, 4Department of Neuroscience and Experimental Therapeutics, Albany Medical College

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Neste estudo, nós descrevemos um procedimento detalhado da fibrose intestinal TNBS-negociada, que exibe a patofisiologia comparável à fibrose de Crohn. Nós igualmente discutimos esta aproximação à luz do rapamicina facilitamos efeitos inibitórios na fibrose intestinal.

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Imunologia e infecção fibrose intestinal mediada por TNBS doença de Crohn inflamação rapamicina autofagia macrófago residente expressão gênica
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