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Journal / Bioengineering / DNA-spenningssonder for å kartlegge immuncellers…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
DNA-spenningssonder for å kartlegge immuncellers forbigående piconeton-reseptorkrefter
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DNA-spenningssonder for å kartlegge immuncellers forbigående piconeton-reseptorkrefter

Article DOI: 10.3791/62348-v • 06:53 min • March 20th, 2021
March 20th, 2021 •
1, 2, 1, 1, 2, 1,2
1Department of Chemistry, Emory University, 2Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University

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Dette papiret beskriver en detaljert protokoll for bruk av DNA-baserte spenningsprober for å avbilde reseptorkreftene som påføres av immunceller. Denne tilnærmingen kan kartlegge reseptorkrefter >4.7pN i sanntid og kan integrere krefter over tid.

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Denne måneden i JoVE utgave 169 DNA-spenningsprober mekanobiologi reseptorkraft piconewton-krefter immunceller kartlegging
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