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JoVE Journal Developmental Biology
Geração de organoides pulmonares 3D inteiros de células-tronco pluripotentes induzidas para modelagem da biologia e doença do desenvolvimento pulmonar
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Geração de organoides pulmonares 3D inteiros de células-tronco pluripotentes induzidas para modelagem da biologia e doença do desenvolvimento pulmonar

Article DOI: 10.3791/62456-v • 09:45 min • April 12th, 2021
April 12th, 2021 •
1,2,3, 2,3, 2,3, 1,2,3
1Department of Pediatrics, University of California, San Diego School of Medicine, 2Sanford Consortium for Regenerative Medicine, 3Sanford Burnham Prebys Medical Discovery Institute

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O artigo descreve a diferenciação direcionada de células-tronco pluripotentes induzidas a organoides pulmonares inteiros tridimensionais contendo células pulmonares epiteliais proximais e disais, juntamente com mesenchyme.

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Biologia do Desenvolvimento Questão 170 células-tronco pluripotentes humanas endoderme células progenitoras pulmonares organoides pulmonares 3D inteiros células epiteliais pulmonares células mesenquimais pulmonares desenvolvimento pulmonar modelagem de doenças pulmonares
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