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JoVE Journal Bioengineering
Ensamblaje de modelos de bicapa lipídica soportada y suspendida de imitación celular para el estudio de interacciones moleculares
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Ensamblaje de modelos de bicapa lipídica soportada y suspendida de imitación celular para el estudio de interacciones moleculares

Article DOI: 10.3791/62599-v • 12:18 min • August 3rd, 2021
August 3rd, 2021 •
1, 2, 2
1Department of Chemical Engineering, Worcester Polytechnic Institute, 2Center for Biomedical Engineering, School of Engineering, Brown University

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Este protocolo describe la formación de vesículas unilipídicas y multilipídicas que imitan a las células, bicapas lipídicas soportadas y bicapas lipídicas suspendidas. Estos modelos in vitro se pueden adaptar para incorporar una variedad de tipos de lípidos y se pueden utilizar para investigar diversas interacciones de moléculas y macromoléculas.

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Bioingeniería Número 174
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