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Journal / Biochemistry / Bioluminescerande optogenetik 2.0: Utnyttja…
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Biochemistry

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JoVE Journal Biochemistry
Bioluminescerande optogenetik 2.0
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Bioluminescerande optogenetik 2.0: Utnyttja bioluminescens för att aktivera fotosensoriska proteiner in vitro och in vivo

Article DOI: 10.3791/62850-v • 07:19 min • August 4th, 2021
August 4th, 2021 •
1,2, 1, 1, 1,2,3
1College of Medicine, Central Michigan University, 2Biochemistry, Cell and Molecular Biology Program, Central Michigan University, 3Neuroscience Program, Central Michigan University

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Bioluminescens-ljus som emitteras av ett luciferasenzym som oxiderar ett småmolekylärt substrat, ett luciferin-kan utnyttjas för att aktivera fotosensoriska proteiner, vilket ger ytterligare en dimension till ljusstimulering och möjliggör manipulation av en mängd ljusmedierade funktioner i celler över temporala och rumsliga skalor.

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Biokemi utgåva 174
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