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Journal / Biochemistry / DetectSyn: En hurtig, upartisk fluorescerende…
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Biochemistry

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DetectSyn: En hurtig, upartisk fluorescerende metode til at detektere ændringer i synapsdensitet

Article DOI: 10.3791/63139-v • 09:10 min • July 22nd, 2022
July 22nd, 2022 •
1,2, 2, 1,2
1Wake Forest Translational Alcohol Research Center, Wake Forest School of Medicine, 2Physiology and Pharmacology, Wake Forest School of Medicine

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DetectSyn er et upartisk, hurtigt fluorescerende assay, der måler ændringer i relativ synaps (præ- og postsynaptisk engagement) antal på tværs af behandlinger eller sygdomstilstande. Denne teknik anvender en nærhedsligeringsteknik, der kan bruges både i dyrkede neuroner og fast væv.

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