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Journal / Cancer Research / High-Content-Screening-Assay zur Identifizierung…
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JoVE Journal Cancer Research
High-Content-Screening-Assay zur Identifizierung von Antikörper-abhängigen zellulären Zytotoxizitäts-modifizierenden Verbindungen
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High-Content-Screening-Assay zur Identifizierung von Antikörper-abhängigen zellulären Zytotoxizitäts-modifizierenden Verbindungen

Article DOI: 10.3791/64485-v • 13:59 min • August 18th, 2023
August 18th, 2023 •
*1,2, *1,3, *1,3, 1, 1,4, 1,4
1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 2Doctoral School of Molecular Medicine, University of Debrecen, 3National Academy of Scientist Education, University of Debrecen, 4ELKH-DE Cell Biology and Signaling Research Group
* These authors contributed equally

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Dieses Protokoll stellt eine automatisierte, bildbasierte Hochdurchsatztechnik vor, um Verbindungen zu identifizieren, die die natürliche Killerzell-vermittelte Abtötung von Brustkrebszellen in Gegenwart eines therapeutischen Anti-HER2-Antikörpers modulieren.

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