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Cancer Research

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JoVE Journal Cancer Research

알데히드 탈수소효소 1A1 활성을 기반으로 난소암 세포를 계층화하기 위한 AlDeSense 적용

Modeling the Effects of Hemodynamic Stress on Circulating Tumor Cells using a Syringe and Needle

Journal (Cancer Research)

Modeling the Effects of Hemodynamic Stress on Circulating Tumor Cells using a Syringe and Needle

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

Journal (Cancer Research)

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

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알데히드 탈수소효소 1A1 활성을 기반으로 난소암 세포를 계층화하기 위한 AlDeSense 적용

Article DOI: 10.3791/64713-v • 09:59 min • March 31st, 2023

March 31st, 2023 •

Michael C. Lee*^1,3,4, Sarah H. Gardner*^2,3,4, Rodrigo Tapia Hernandez^1,3,4, Jefferson Chan^1,2,3,4

¹Department of Chemistry, University of Illinois Urbana-Champaign, ²Department of Biochemistry, University of Illinois Urbana-Champaign, ³Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, ⁴Cancer Center of Illinois, University of Illinois Urbana-Champaign

* These authors contributed equally

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살아있는 세포에서 ALDH1A1 활성을 측정하는 방법은 줄기의 바이오마커로서의 지위로 인해 암 연구에서 매우 중요합니다. 이 연구에서 우리는 5개의 난소암 세포주 패널에서 ALDH1A1 활성의 상대적 수준을 결정하기 위해 동형 선택적 형광 프로브를 사용했습니다.

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