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Journal / Bioengineering / 使用便携式台式聚焦超声系统治疗小鼠模型中多形性胶质母细胞瘤的声动力疗法…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
使用便携式台式聚焦超声系统治疗小鼠模型中多形性胶质母细胞瘤的声动力疗法
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使用便携式台式聚焦超声系统治疗小鼠模型中多形性胶质母细胞瘤的声动力疗法

Article DOI: 10.3791/65114-v • 09:07 min • February 10th, 2023
February 10th, 2023 •
1,2, 1,2, 3, 1,2, 4, 1, 1, 5, 1, 1,2,4,6,7
1Department of Neurosurgery, Johns Hopkins University School of Medicine, 2Department of Biomedical Engineering, Johns Hopkins University, 3Krieger School of Arts and Sciences, Johns Hopkins University, 4Department of Electrical Engineering and Computer Science, Johns Hopkins University, 5Department of Radiology, Cancer Imaging Division, Johns Hopkins University School of Medicine, 6Department of Mechanical Engineering, Johns Hopkins University, 7Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine

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在这里，我们描述了一个方案，该方案详细说明了如何使用磁共振引导的聚焦超声在 体内 小鼠胶质母细胞瘤模型中进行声动力治疗。

Tags

声动力疗法， 多形性胶质母细胞瘤， 小鼠模型， 聚焦超声系统， 超声增敏剂， 提高灵敏度， 临床治疗， 长期生存率， 无创治疗， 肿瘤特异性治疗， 超声增敏剂， 反应性氧化物种， 细胞凋亡， 标准化参数， 临床前研究， 治疗策略优化， 临床前GBM啮齿动物模型， 磁共振引导FUS（MRgFUS）， 特异性靶向， 脑肿瘤， 台式设备
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