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Fokuseret ultralydneuromodulation af humane in vitro neurale kulturer i multi-well mikroelektrode arrays…
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Neuroscience
Neuroscience
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Fokuseret ultralydneuromodulation af humane in vitro neurale kulturer i multi-well mikroelektrode arrays
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Article
DOI:
10.3791/65115-v
•
04:00 min
•
May 3rd, 2024
Fokuseret ultralydneuromodulation af humane in vitro neurale kulturer i multi-well mikroelektrode arrays
May 3rd, 2024
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Ruixing Liang1,2, Griffin Mess2,3, Joshua Punnoose2,3, Kelley M. Kempski Leadingham2,3, Constantin Smit2,3, Nitish Thakor1,4, Christa W. Habela3, Betty Tyler3, Yousef Salimpour3, Amir Manbachi1,2,3,4,5,6
1Electrical and Computer Engineering, Johns Hopkins University, 2HEPIUS Innovation Laboratory, Johns Hopkins University School of Medicine, 3Neurosurgery, Johns Hopkins University School of Medicine, 4Biomedical Engineering, Johns Hopkins University School of Medicine, 5Mechanical Engineering, Johns Hopkins University, 6Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine
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Summary
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Click here for the English version.
Her præsenterer vi en protokol til brug af et high-throughput system, der muliggør overvågning og kvantificering af de neuromodulerende virkninger af fokuseret ultralyd på menneskeinducerede pluripotente stamcelle (HiPSC) neuroner.