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Evaluating Murine BBB Disruption Induced by Hypoxic Human Placenta-Derived sEVs

January 26th, 2024
*1, *1,2, 1, 3, 3,4, 1, 5, 1, 1, 1,6
1Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, Chillan, 2Nursery School, Health Faculty, Universidad Santo Tomás, Los Angeles, 3Obstetrics and Gynecology Department, Herminda Martin Clinical Hospital, Chillan, 4Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepcion, 5Laboratory of Animal Biotechnology, Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepción, Chillan, 6Group of Research and Innovation in Vascular Health (GRIVAS Health), Chillan
* These authors contributed equally

Summary
Automatic Translation

Er wordt een protocol gepresenteerd om te evalueren of kleine EV's (sEV's) geïsoleerd uit placenta-explantaten gekweekt onder hypoxische omstandigheden (modellering van één aspect van pre-eclampsie) de bloed-hersenbarrière verstoren bij niet-zwangere volwassen vrouwelijke muizen.

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