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Evaluating Murine BBB Disruption Induced by Hypoxic Human Placenta-Derived sEVs

January 26th, 2024
*1, *1,2, 1, 3, 3,4, 1, 5, 1, 1, 1,6
1Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, Chillan, 2Nursery School, Health Faculty, Universidad Santo Tomás, Los Angeles, 3Obstetrics and Gynecology Department, Herminda Martin Clinical Hospital, Chillan, 4Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepcion, 5Laboratory of Animal Biotechnology, Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepción, Chillan, 6Group of Research and Innovation in Vascular Health (GRIVAS Health), Chillan
* These authors contributed equally

Summary
Automatic Translation

Es wird ein Protokoll vorgestellt, um zu evaluieren, ob kleine EVs (sEVs), die aus Plazenta-Explantaten isoliert wurden, die unter hypoxischen Bedingungen kultiviert wurden (ein Aspekt der Präeklampsie modellierend), die Blut-Hirn-Schranke bei nicht schwangeren erwachsenen weiblichen Mäusen stören.

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