Benita Middleton Chronobiology, Faculty of Health & Medical Sciences University of Surrey Biography Publications Institution JoVE Articles Benita Middleton has not added a biography. If you are Benita Middleton and would like to personalize this page please email our Author Liaison for assistance. Publications Increased Plasma Melatonin in Presymptomatic Huntington Disease Sheep (Ovis Aries): Compensatory Neuroprotection in a Neurodegenerative Disease? Journal of Pineal Research. Mar, 2020 | Pubmed ID: 31742766 Effect of Acute Total Sleep Deprivation on Plasma Melatonin, Cortisol and Metabolite Rhythms in Females The European Journal of Neuroscience. Jan, 2020 | Pubmed ID: 30929284 Resetting the Late Timing of 'night Owls' Has a Positive Impact on Mental Health and Performance Sleep Medicine. 08, 2019 | Pubmed ID: 31202686 Circadian Phenotype Impacts the Brain's Resting-state Functional Connectivity, Attentional Performance, and Sleepiness Sleep. 05, 2019 | Pubmed ID: 30763951 Chronic Sleep Restriction in the Rotenone Parkinson's Disease Model in Rats Reveals Peripheral Early-phase Biomarkers Scientific Reports. 02, 2019 | Pubmed ID: 30760786 Melatonin As an Adjunct to Therapeutic Hypothermia in a Piglet Model of Neonatal Encephalopathy: A Translational Study Neurobiology of Disease. 01, 2019 | Pubmed ID: 30300675 Preventing PTSD, Depression and Associated Health Problems in Student Paramedics: Protocol for PREVENT-PTSD, a Randomised Controlled Trial of Supported Online Cognitive Training for Resilience Versus Alternative Online Training and Standard Practice BMJ Open. 12, 2018 | Pubmed ID: 30598484 Morning Bright Light Treatment for Sleep-Wake Disturbances in Primary Biliary Cholangitis: A Pilot Study Frontiers in Physiology. 2018 | Pubmed ID: 30455647 A Systems Genetics Resource and Analysis of Sleep Regulation in the Mouse PLoS Biology. 08, 2018 | Pubmed ID: 30091978 Separation of Circadian- and Behavior-driven Metabolite Rhythms in Humans Provides a Window on Peripheral Oscillators and Metabolism Proceedings of the National Academy of Sciences of the United States of America. 07, 2018 | Pubmed ID: 29991600 Human Fronto-parietal Response Scattering Subserves Vigilance at Night NeuroImage. 07, 2018 | Pubmed ID: 29604455 Erratum To: Investigation of Metabolites for Estimating Blood Deposition Time International Journal of Legal Medicine. 01, 2018 | Pubmed ID: 28840223 Investigation of Metabolites for Estimating Blood Deposition Time International Journal of Legal Medicine. Jan, 2018 | Pubmed ID: 28780758 Human Seasonal and Circadian Studies in Antarctica (Halley, 75°S) General and Comparative Endocrinology. 03, 2018 | Pubmed ID: 28526480 Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia Frontiers in Physiology. 2017 | Pubmed ID: 28912724 Blue-Enriched Lighting for Older People Living in Care Homes: Effect on Activity, Actigraphic Sleep, Mood and Alertness Current Alzheimer Research. 2017 | Pubmed ID: 28595523 Meal Timing Regulates the Human Circadian System Current Biology : CB. Jun, 2017 | Pubmed ID: 28578930 A Single Night Light Exposure Acutely Alters Hormonal and Metabolic Responses in Healthy Participants Endocrine Connections. Feb, 2017 | Pubmed ID: 28270559 Metabolic Profiling of Presymptomatic Huntington's Disease Sheep Reveals Novel Biomarkers Scientific Reports. 02, 2017 | Pubmed ID: 28223686 Circadian Dynamics in Measures of Cortical Excitation and Inhibition Balance Scientific Reports. 09, 2016 | Pubmed ID: 27651114 Local Modulation of Human Brain Responses by Circadian Rhythmicity and Sleep Debt Science (New York, N.Y.). Aug, 2016 | Pubmed ID: 27516598 Circadian Regulation of Human Cortical Excitability Nature Communications. 06, 2016 | Pubmed ID: 27339884 Seasonality in Human Cognitive Brain Responses Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016 | Pubmed ID: 26858432 Sex Differences in the Circadian Profiles of Melatonin and Cortisol in Plasma and Urine Matrices Under Constant Routine Conditions Chronobiology International. 2016 | Pubmed ID: 26731571 Bigger, Brighter, Bluer-Better? Current Light-Emitting Devices - Adverse Sleep Properties and Preventative Strategies Frontiers in Public Health. 2015 | Pubmed ID: 26528465 Increased and Mistimed Sex Hormone Production in Night Shift Workers Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Mar, 2015 | Pubmed ID: 25737330 The Relationship Between Work-related Rumination and Evening and Morning Salivary Cortisol Secretion Stress and Health : Journal of the International Society for the Investigation of Stress. Apr, 2015 | Pubmed ID: 24166947 Effect of Sleep Deprivation on the Human Metabolome Proceedings of the National Academy of Sciences of the United States of America. Jul, 2014 | Pubmed ID: 25002497 Circadian Variation of Melatonin, Light Exposure, and Diurnal Preference in Day and Night Shift Workers of Both Sexes Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2014 | Pubmed ID: 24812038 Measurement of Melatonin and 6-sulphatoxymelatonin Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23996364 Daily Rhythms of Plasma Melatonin, but Not Plasma Leptin or Leptin MRNA, Vary Between Lean, Obese and Type 2 Diabetic Men PloS One. 2012 | Pubmed ID: 22623983 Sleep and Circadian Rhythm Disruption in Schizophrenia The British Journal of Psychiatry : the Journal of Mental Science. Apr, 2012 | Pubmed ID: 22194182 Age-related Changes in Acute and Phase-advancing Responses to Monochromatic Light Journal of Biological Rhythms. Feb, 2009 | Pubmed ID: 19227580 Measuring Melatonin in Humans Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine. Feb, 2008 | Pubmed ID: 18350967 Robust Circadian Rhythm in Heart Rate and Its Variability: Influence of Exogenous Melatonin and Photoperiod Journal of Sleep Research. Jun, 2007 | Pubmed ID: 17542944 Measurement of Melatonin and 6-sulphatoxymelatonin Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16761382 Sleep and Circadian Phase in a Ship's Crew Journal of Biological Rhythms. Jun, 2006 | Pubmed ID: 16731661 Mice Convert Melatonin to 6-sulphatoxymelatonin General and Comparative Endocrinology. Jul, 2006 | Pubmed ID: 16564048 Light-induced Melatonin Suppression: Age-related Reduction in Response to Short Wavelength Light Experimental Gerontology. Mar, 2005 | Pubmed ID: 15763401 Melatonin Advances the Circadian Timing of EEG Sleep and Directly Facilitates Sleep Without Altering Its Duration in Extended Sleep Opportunities in Humans The Journal of Physiology. Nov, 2004 | Pubmed ID: 15459246 Melatonin Phase-shifts Human Circadian Rhythms with No Evidence of Changes in the Duration of Endogenous Melatonin Secretion or the 24-hour Production of Reproductive Hormones The Journal of Clinical Endocrinology and Metabolism. Sep, 2003 | Pubmed ID: 12970302 Human Circadian Phase in 12:12 H, 200: <8 Lux and 1000: <8 Lux Light-dark Cycles, Without Scheduled Sleep or Activity Neuroscience Letters. Aug, 2002 | Pubmed ID: 12161258 Human Circadian Phenotyping and Diurnal Performance Testing in the Real World Elise R. Facer-Childs1,2,3, Benita Middleton1, Andrew P. Bagshaw2, Debra J. Skene1 1Chronobiology, Faculty of Health & Medical Sciences, University of Surrey, 2Centre for Human Brain Health, University of Birmingham, 3Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University JoVE 60448 Behavior
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World Elise R. Facer-Childs1,2,3, Benita Middleton1, Andrew P. Bagshaw2, Debra J. Skene1 1Chronobiology, Faculty of Health & Medical Sciences, University of Surrey, 2Centre for Human Brain Health, University of Birmingham, 3Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University JoVE 60448 Behavior