Bruce A. Vallance Division of Gastroenterology BC Children's Hospital Biography Publications Institution JoVE Articles Bruce A. Vallance has not added a biography. If you are Bruce A. Vallance and would like to personalize this page please email our Author Liaison for assistance. Publications Resistin-like Molecule α Promotes Pathogenic Th17 Cell Responses and Bacterial-Induced Intestinal Inflammation Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23355735 Active Vitamin D (1,25-dihydroxyvitamin D3) Increases Host Susceptibility to Citrobacter Rodentium by Suppressing Mucosal Th17 Responses American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2012 | Pubmed ID: 23019194 MyD88 Signaling Promotes Both Mucosal Homeostatic and Fibrotic Responses During Salmonella-induced Colitis American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2012 | Pubmed ID: 22679002 Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota Science (New York, N.Y.). Jun, 2012 | Pubmed ID: 22582016 Innate Host Responses to Enteric Bacterial Pathogens: a Balancing Act Between Resistance and Tolerance Cellular Microbiology. Apr, 2012 | Pubmed ID: 22233392 Attaching and Effacing Bacterial Effector NleC Suppresses Epithelial Inflammatory Responses by Inhibiting NF-κB and P38 Mitogen-activated Protein Kinase Activation Infection and Immunity. Sep, 2011 | Pubmed ID: 21746856 Citrobacter Rodentium Infection Induces MyD88-dependent Formation of Ubiquitinated Protein Aggregates in the Intestinal Epithelium Journal of Innate Immunity. 2011 | Pubmed ID: 20962508 Dissemination of Invasive Salmonella Via Bacterial-induced Extrusion of Mucosal Epithelia Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20876119 Interleukin-11 Reduces TLR4-induced Colitis in TLR2-deficient Mice and Restores Intestinal STAT3 Signaling Gastroenterology. Oct, 2010 | Pubmed ID: 20600022 Epithelial P38alpha Controls Immune Cell Recruitment in the Colonic Mucosa PLoS Pathogens. 2010 | Pubmed ID: 20532209 Muc2 Protects Against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa PLoS Pathogens. May, 2010 | Pubmed ID: 20485566 Loss of Single Immunoglobulin Interlukin-1 Receptor-related Molecule Leads to Enhanced Colonic Polyposis in Apc(min) Mice Gastroenterology. Aug, 2010 | Pubmed ID: 20416302 The Pathogenic E. Coli Type III Effector EspZ Interacts with Host CD98 and Facilitates Host Cell Prosurvival Signalling Cellular Microbiology. Sep, 2010 | Pubmed ID: 20374249 Control of Intestinal Homeostasis, Colitis, and Colitis-associated Colorectal Cancer by the Inflammatory Caspases Immunity. Mar, 2010 | Pubmed ID: 20226691 The Single IgG IL-1-related Receptor Controls TLR Responses in Differentiated Human Intestinal Epithelial Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20130217 Salmonella Infection of Gallbladder Epithelial Cells Drives Local Inflammation and Injury in a Model of Acute Typhoid Fever The Journal of Infectious Diseases. Dec, 2009 | Pubmed ID: 19852670 Absence of Stearoyl-CoA Desaturase-1 Does Not Promote DSS-induced Acute Colitis Biochimica Et Biophysica Acta. Dec, 2009 | Pubmed ID: 19695343 Nramp1 Drives an Accelerated Inflammatory Response During Salmonella-induced Colitis in Mice Cellular Microbiology. Feb, 2009 | Pubmed ID: 19016783 Intestinal Microbiota Are Transiently Altered During Salmonella-induced Gastroenteritis Expert Review of Gastroenterology & Hepatology. Aug, 2008 | Pubmed ID: 19072400 Nramp1 Expression by Dendritic Cells Modulates Inflammatory Responses During Salmonella Typhimurium Infection Cellular Microbiology. Aug, 2008 | Pubmed ID: 18397382 A Novel Secretion Pathway of Salmonella Enterica Acts As an Antivirulence Modulator During Salmonellosis PLoS Pathogens. Apr, 2008 | Pubmed ID: 18389060 Chronic Enteric Salmonella Infection in Mice Leads to Severe and Persistent Intestinal Fibrosis Gastroenterology. Mar, 2008 | Pubmed ID: 18325390 Flagellin-dependent and -independent Inflammatory Responses Following Infection by Enteropathogenic Escherichia Coli and Citrobacter Rodentium Infection and Immunity. Apr, 2008 | Pubmed ID: 18227166 Role of M-CSF-dependent Macrophages in Colitis is Driven by the Nature of the Inflammatory Stimulus American Journal of Physiology. Gastrointestinal and Liver Physiology. Mar, 2008 | Pubmed ID: 18202111 Modulation of Intestinal Goblet Cell Function During Infection by an Attaching and Effacing Bacterial Pathogen Infection and Immunity. Feb, 2008 | Pubmed ID: 17984203 Toll-like Receptor 2 Plays a Critical Role in Maintaining Mucosal Integrity During Citrobacter Rodentium-induced Colitis Cellular Microbiology. Feb, 2008 | Pubmed ID: 17910742 The Toll-interleukin-1 Receptor Member SIGIRR Regulates Colonic Epithelial Homeostasis, Inflammation, and Tumorigenesis Immunity. Apr, 2007 | Pubmed ID: 17398123 IL-4 Gene Transfer to the Small Bowel Serosa Leads to Intestinal Inflammation and Smooth Muscle Hyperresponsiveness American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2007 | Pubmed ID: 17215437 Genetic Profiling of Dendritic Cells Exposed to Live- or Ultraviolet-irradiated Chlamydia Muridarum Reveals Marked Differences in CXC Chemokine Profiles Immunology. Feb, 2007 | Pubmed ID: 17073942 Citrobacter Rodentium Infection Causes Both Mitochondrial Dysfunction and Intestinal Epithelial Barrier Disruption in Vivo: Role of Mitochondrial Associated Protein (Map) Cellular Microbiology. Oct, 2006 | Pubmed ID: 16759225 Toll-like Receptor 4 Contributes to Colitis Development but Not to Host Defense During Citrobacter Rodentium Infection in Mice Infection and Immunity. May, 2006 | Pubmed ID: 16622187 Noradrenergic and Cholinergic Neural Pathways Mediate Stress-induced Reactivation of Colitis in the Rat Autonomic Neuroscience : Basic & Clinical. Jan, 2006 | Pubmed ID: 16464645 Salmonella Pathogenicity Island 2 is Expressed Prior to Penetrating the Intestine PLoS Pathogens. Nov, 2005 | Pubmed ID: 16304611 Cloning Vectors and Fluorescent Proteins Can Significantly Inhibit Salmonella Enterica Virulence in Both Epithelial Cells and Macrophages: Implications for Bacterial Pathogenesis Studies Infection and Immunity. Oct, 2005 | Pubmed ID: 16177386 Salmonella Enterica Serovar Typhimurium Pathogenicity Island 2 is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis Infection and Immunity. Jun, 2005 | Pubmed ID: 15908346 Modulation of Host Cytoskeleton Function by the Enteropathogenic Escherichia Coli and Citrobacter Rodentium Effector Protein EspG Infection and Immunity. May, 2005 | Pubmed ID: 15845460 TGF-beta1 Gene Transfer to the Mouse Colon Leads to Intestinal Fibrosis American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2005 | Pubmed ID: 15778431 Myenteric Plexus Injury and Apoptosis in Experimental Colitis Autonomic Neuroscience : Basic & Clinical. Jan, 2005 | Pubmed ID: 15620569 SseK1 and SseK2 Are Novel Translocated Proteins of Salmonella Enterica Serovar Typhimurium Infection and Immunity. Sep, 2004 | Pubmed ID: 15322005 Relative Contributions of NOS Isoforms During Experimental Colitis: Endothelial-derived NOS Maintains Mucosal Integrity American Journal of Physiology. Gastrointestinal and Liver Physiology. Oct, 2004 | Pubmed ID: 15217783 Clearance of Citrobacter Rodentium Requires B Cells but Not Secretory Immunoglobulin A (IgA) or IgM Antibodies Infection and Immunity. Jun, 2004 | Pubmed ID: 15155635 Toll-like Receptor 4 Dependence of Innate and Adaptive Immunity to Salmonella: Importance of the Kupffer Cell Network Journal of Immunology (Baltimore, Md. : 1950). May, 2004 | Pubmed ID: 15128808 Dissecting Virulence: Systematic and Functional Analyses of a Pathogenicity Island Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14988506 Salmonella Type III Effectors PipB and PipB2 Are Targeted to Detergent-resistant Microdomains on Internal Host Cell Membranes Molecular Microbiology. Aug, 2003 | Pubmed ID: 12864852 SseA is Required for Translocation of Salmonella Pathogenicity Island-2 Effectors into Host Cells Microbes and Infection / Institut Pasteur. Jun, 2003 | Pubmed ID: 12787732 Host Susceptibility to the Attaching and Effacing Bacterial Pathogen Citrobacter Rodentium Infection and Immunity. Jun, 2003 | Pubmed ID: 12761129 Citrobacter Rodentium Translocated Intimin Receptor (Tir) is an Essential Virulence Factor Needed for Actin Condensation, Intestinal Colonization and Colonic Hyperplasia in Mice Molecular Microbiology. Apr, 2003 | Pubmed ID: 12657048 SopD2 is a Novel Type III Secreted Effector of Salmonella Typhimurium That Targets Late Endocytic Compartments Upon Delivery into Host Cells Traffic (Copenhagen, Denmark). Jan, 2003 | Pubmed ID: 12535274 Current Progress in Enteropathogenic and Enterohemorrhagic Escherichia Coli Vaccines Expert Review of Vaccines. Dec, 2002 | Pubmed ID: 12901587 Enteropathogenic and Enterohemorrhagic Escherichia Coli Infections: Emerging Themes in Pathogenesis and Prevention Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. Nov, 2002 | Pubmed ID: 12464970 Host-pathogen Interactions: Host Resistance Factor Nramp1 Up-regulates the Expression of Salmonella Pathogenicity Island-2 Virulence Genes Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002 | Pubmed ID: 12441401 Modulation of Inducible Nitric Oxide Synthase Expression by the Attaching and Effacing Bacterial Pathogen Citrobacter Rodentium in Infected Mice Infection and Immunity. Nov, 2002 | Pubmed ID: 12379723 Salmonella Effectors Within a Single Pathogenicity Island Are Differentially Expressed and Translocated by Separate Type III Secretion Systems Molecular Microbiology. Mar, 2002 | Pubmed ID: 11918798 Mice Lacking T and B Lymphocytes Develop Transient Colitis and Crypt Hyperplasia Yet Suffer Impaired Bacterial Clearance During Citrobacter Rodentium Infection Infection and Immunity. Apr, 2002 | Pubmed ID: 11895973 DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat Vijay Morampudi*1, Ganive Bhinder*1, Xiujuan Wu1, Chuanbin Dai1, Ho Pan Sham1, Bruce A. Vallance1, Kevan Jacobson1 1Division of Gastroenterology, BC Children's Hospital JoVE 51297 Medicine The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis Ganive Bhinder1, Ho Pan Sham1, Justin M. Chan1, Vijay Morampudi1, Kevan Jacobson1, Bruce A. Vallance1 1Division of Gastroenterology, BC Children's Hospital JoVE 50222 Immunology and Infection
DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat Vijay Morampudi*1, Ganive Bhinder*1, Xiujuan Wu1, Chuanbin Dai1, Ho Pan Sham1, Bruce A. Vallance1, Kevan Jacobson1 1Division of Gastroenterology, BC Children's Hospital JoVE 51297 Medicine
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis Ganive Bhinder1, Ho Pan Sham1, Justin M. Chan1, Vijay Morampudi1, Kevan Jacobson1, Bruce A. Vallance1 1Division of Gastroenterology, BC Children's Hospital JoVE 50222 Immunology and Infection