Demin Zhou State Key Laboratory of Natural and Biomimetic Drugs Peking University Biography Publications Institution JoVE Articles Demin Zhou has not added a biography. If you are Demin Zhou and would like to personalize this page please email our Author Liaison for assistance. Publications Truncateols O-V, Further Isoprenylated Cyclohexanols from the Sponge-associated Fungus Truncatella Angustata with Antiviral Activities Phytochemistry. Nov, 2018 | Pubmed ID: 30077121 Design, Synthesis and Biological Evaluation of Water-soluble Per-O-methylated Cyclodextrin-C Conjugates As Anti-influenza Virus Agents European Journal of Medicinal Chemistry. Feb, 2018 | Pubmed ID: 29407950 Precision Fluorescent Labeling of an Adeno-Associated Virus Vector to Monitor the Viral Infection Pathway Biotechnology Journal. Apr, 2018 | Pubmed ID: 29356431 Recent Progress in the Antiviral Activity and Mechanism Study of Pentacyclic Triterpenoids and Their Derivatives Medicinal Research Reviews. 05, 2018 | Pubmed ID: 29350407 Synthesis of Novel Pentacyclic Triterpene-Neu5Ac2en Derivatives and Investigation of Their Anti-influenza Entry Activity MedChemComm. Jul, 2017 | Pubmed ID: 30108865 A Nanosystem of Amphiphilic Oligopeptide-Drug Conjugate Actualizing Both αvβ3 Targeting and Reduction-Triggered Release for Maytansinoid Theranostics. 2017 | Pubmed ID: 28900511 Redirecting Killer T Cells Through Incorporation of Azido Sugars for Tethering Ligands Chembiochem : a European Journal of Chemical Biology. 11, 2017 | Pubmed ID: 28862366 Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity Molecules (Basel, Switzerland). Jul, 2017 | Pubmed ID: 28696391 Construction of an Inducible Stable Cell Line for Efficient Incorporation of Unnatural Amino Acids in Mammalian Cells Biochemical and Biophysical Research Communications. 08, 2017 | Pubmed ID: 28576486 Eg5 Inhibitor YL001 Induces Mitotic Arrest and Inhibits Tumor Proliferation Oncotarget. Jun, 2017 | Pubmed ID: 28489567 Fatty Acid Synthase Cooperates with Protrudin to Facilitate Membrane Outgrowth of Cellular Protrusions Scientific Reports. Apr, 2017 | Pubmed ID: 28429738 Inhibition of Influenza Virus Infection by Multivalent Pentacyclic Triterpene-functionalized Per-O-methylated Cyclodextrin Conjugates European Journal of Medicinal Chemistry. Jul, 2017 | Pubmed ID: 28411453 Design, Synthesis and Biological Evaluation of Gentiopicroside Derivatives As Potential Antiviral Inhibitors European Journal of Medicinal Chemistry. Apr, 2017 | Pubmed ID: 28254701 Precise and Combinatorial PEGylation Generates a Low-immunogenic and Stable Form of Human Growth Hormone Journal of Controlled Release : Official Journal of the Controlled Release Society. 03, 2017 | Pubmed ID: 28131652 AC220 and AraC Cause Differential Inhibitory Dynamics in Patient-derived M5-AML with FLT3-ITD And, Thus, Ultimately Distinct Therapeutic Outcomes Experimental Hematology. Jan, 2017 | Pubmed ID: 27670587 Generation of Influenza A Viruses As Live but Replication-incompetent Virus Vaccines Science (New York, N.Y.). 12, 2016 | Pubmed ID: 27934767 Synthesis of Site-Specific Radiolabeled Antibodies for Radioimmunotherapy Via Genetic Code Expansion Bioconjugate Chemistry. Oct, 2016 | Pubmed ID: 27617674 Synthesis and Biological Evaluation of Novel Pentacyclic Triterpene α-cyclodextrin Conjugates As HCV Entry Inhibitors European Journal of Medicinal Chemistry. Nov, 2016 | Pubmed ID: 27565552 Overexpression of AKR1C3 Significantly Enhances Human Prostate Cancer Cells Resistance to Radiation Oncotarget. 07, 2016 | Pubmed ID: 27385003 Re-exploration of the Codon Context Effect on Amber Codon-Guided Incorporation of Noncanonical Amino Acids in Escherichia Coli by the Blue-White Screening Assay Chembiochem : a European Journal of Chemical Biology. 07, 2016 | Pubmed ID: 27028123 Data on Interaction Between Adeno-associated Virus and U87 Cell Via CRGD Chemical Modification Data in Brief. Jun, 2016 | Pubmed ID: 26958635 Inter-molecular β-sheet Structure Facilitates Lung-targeting SiRNA Delivery Scientific Reports. Mar, 2016 | Pubmed ID: 26955887 Design, Synthesis and Biological Evaluation of Novel L-ascorbic Acid-conjugated Pentacyclic Triterpene Derivatives As Potential Influenza Virus Entry Inhibitors European Journal of Medicinal Chemistry. Mar, 2016 | Pubmed ID: 26866456 Bioactive Constituents of Glycyrrhiza Uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine Journal of Natural Products. Feb, 2016 | Pubmed ID: 26841168 CRISPRi-Manipulation of Genetic Code Expansion Via RF1 for Reassignment of Amber Codon in Bacteria Scientific Reports. Jan, 2016 | Pubmed ID: 26818534 Development of Next Generation Adeno-associated Viral Vectors Capable of Selective Tropism and Efficient Gene Delivery Biomaterials. Feb, 2016 | Pubmed ID: 26708090 Spiromastilactones: A New Class of Influenza Virus Inhibitors from Deep-sea Fungus European Journal of Medicinal Chemistry. Jan, 2016 | Pubmed ID: 26686929 Pentacyclic Triterpenes Grafted on CD Cores to Interfere with Influenza Virus Entry: A Dramatic Multivalent Effect Biomaterials. Feb, 2016 | Pubmed ID: 26686050 Potential Involvement of MiR-375 in the Premalignant Progression of Oral Squamous Cell Carcinoma Mediated Via Transcription Factor KLF5 Oncotarget. Nov, 2015 | Pubmed ID: 26474386 Synthesis and Biological Evaluation of Ring A And/or C Expansion and Opening Echinocystic Acid Derivatives for Anti-HCV Entry Inhibitors European Journal of Medicinal Chemistry. Sep, 2015 | Pubmed ID: 26318066 Transition Metal-Free Oxidative Radical Decarboxylation/Cyclization for the Construction of 6-Alkyl/Aryl Phenanthridines The Journal of Organic Chemistry. Sep, 2015 | Pubmed ID: 26302056 Development of Next Generation of Therapeutic IFN-α2b Via Genetic Code Expansion Acta Biomaterialia. Jun, 2015 | Pubmed ID: 25769229 Broadening the Versatility of Lentiviral Vectors As a Tool in Nucleic Acid Research Via Genetic Code Expansion Nucleic Acids Research. Jun, 2015 | Pubmed ID: 25765642 Neoechinulin B and Its Analogues As Potential Entry Inhibitors of Influenza Viruses, Targeting Viral Hemagglutinin European Journal of Medicinal Chemistry. Mar, 2015 | Pubmed ID: 25681711 The Use of α-conotoxin ImI to Actualize the Targeted Delivery of Paclitaxel Micelles to α7 NAChR-overexpressing Breast Cancer Biomaterials. Feb, 2015 | Pubmed ID: 25542793 C-Met Targeting Enhances the Effect of Irradiation and Chemical Agents Against Malignant Colon Cells Harboring a KRAS Mutation PloS One. 2014 | Pubmed ID: 25427200 Elevated Expression of AKR1C3 Increases Resistance of Cancer Cells to Ionizing Radiation Via Modulation of Oxidative Stress PloS One. 2014 | Pubmed ID: 25419901 A Selective NIR-emitting Zinc Sensor by Using Schiff Base Binding to Turn-on Excited-state Intramolecular Proton Transfer Journal of Materials Chemistry. B. 2014 | Pubmed ID: 25411638 Discovery of Pentacyclic Triterpenoids As Potential Entry Inhibitors of Influenza Viruses Journal of Medicinal Chemistry. Dec, 2014 | Pubmed ID: 25383779 TPGS-g-PLGA/Pluronic F68 Mixed Micelles for Tanshinone IIA Delivery in Cancer Therapy International Journal of Pharmaceutics. Dec, 2014 | Pubmed ID: 25223472 A Single Molecular Probe for Multi-analyte (Cr³⁺, Al³⁺ and Fe³⁺) Detection in Aqueous Medium and Its Biological Application Chemical Communications (Cambridge, England). Oct, 2014 | Pubmed ID: 25178169 Response and Adaptation of Escherichia Coli to Suppression of the Amber Stop Codon Chembiochem : a European Journal of Chemical Biology. Aug, 2014 | Pubmed ID: 25044429 Uralsaponins M-Y, Antiviral Triterpenoid Saponins from the Roots of Glycyrrhiza Uralensis Journal of Natural Products. Jul, 2014 | Pubmed ID: 24957203 Development of Bivalent Oleanane-type Triterpenes As Potent HCV Entry Inhibitors European Journal of Medicinal Chemistry. Apr, 2014 | Pubmed ID: 24650713 Synthesis and Anti-HCV Entry Activity Studies of β-cyclodextrin-pentacyclic Triterpene Conjugates ChemMedChem. May, 2014 | Pubmed ID: 24623716 Nitrosporeusines A and B, Unprecedented Thioester-bearing Alkaloids from the Arctic Streptomyces Nitrosporeus Organic Letters. Oct, 2013 | Pubmed ID: 24090410 Development of Oleanane-type Triterpenes As a New Class of HCV Entry Inhibitors Journal of Medicinal Chemistry. Jun, 2013 | Pubmed ID: 23662817 Honokiol Inhibits the Inflammatory Reaction During Cerebral Ischemia Reperfusion by Suppressing NF-κB Activation and Cytokine Production of Glial Cells Neuroscience Letters. Feb, 2013 | Pubmed ID: 23262090 C-Met Inhibitor SU11274 Enhances the Response of the Prostate Cancer Cell Line DU145 to Ionizing Radiation Biochemical and Biophysical Research Communications. Oct, 2012 | Pubmed ID: 23026049 Strand Antagonism in RNAi: an Explanation of Differences in Potency Between Intracellularly Expressed SiRNA and ShRNA Nucleic Acids Research. Feb, 2012 | Pubmed ID: 22039150 A Method for Detecting and Preventing Negative RNA Interference in Preparation of Lentiviral Vectors for SiRNA Delivery RNA (New York, N.Y.). Apr, 2009 | Pubmed ID: 19244361 Immunophenotyping av Orthotopic Homograft (Syngeneic) av Murine primære KPC bukspyttkjertelen Ductal Adenocarcinoma av flowcytometri Xiaoyu An*1,2, Xuesong Ouyang*1, Hui Zhang1, Tingting Li1, Yu-yang Huang1, Zhiyuan Li1, Demin Zhou2, Qi-Xang Li1,2 1Crown Bioscience Inc., 2State Key Laboratory of Natural and Biomimetic Drugs, Peking University JoVE 57460 Cancer Research
Immunophenotyping av Orthotopic Homograft (Syngeneic) av Murine primære KPC bukspyttkjertelen Ductal Adenocarcinoma av flowcytometri Xiaoyu An*1,2, Xuesong Ouyang*1, Hui Zhang1, Tingting Li1, Yu-yang Huang1, Zhiyuan Li1, Demin Zhou2, Qi-Xang Li1,2 1Crown Bioscience Inc., 2State Key Laboratory of Natural and Biomimetic Drugs, Peking University JoVE 57460 Cancer Research