Dirk Schmidt-Arras Institute of Biochemistry Christian-Albrechts-University Biography Publications Institution JoVE Articles Dirk Schmidt-Arras has not added a biography. If you are Dirk Schmidt-Arras and would like to personalize this page please email our Author Liaison for assistance. Publications A Biallelic Mutation in IL6ST Encoding the GP130 Co-receptor Causes Immunodeficiency and Craniosynostosis The Journal of Experimental Medicine. Sep, 2017 | Pubmed ID: 28747427 Microbiomarkers in Inflammatory Bowel Diseases: Caveats Come with Caviar Gut. Oct, 2017 | Pubmed ID: 28733278 Synergistic Killing of FLT3ITD-positive AML Cells by Combined Inhibition of Tyrosine-kinase Activity and N-glycosylation Oncotarget. Apr, 2017 | Pubmed ID: 28460451 IL-6 Trans-signaling is Essential for the Development of Hepatocellular Carcinoma in Mice Hepatology (Baltimore, Md.). Jan, 2017 | Pubmed ID: 27770462 Constitutive Gp130 Activation Rapidly Accelerates the Transformation of Human Hepatocytes Via an Impaired Oxidative Stress Response Oncotarget. Aug, 2016 | Pubmed ID: 27489351 Tetraspanin 8 is an Interactor of the Metalloprotease Meprin β Within Tetraspanin-enriched Microdomains Biological Chemistry. Sep, 2016 | Pubmed ID: 27180358 Tetraspanin 8 is an Interactor of the Metalloprotease Meprin β Within Tetraspanin-enriched Microdomains Biological Chemistry. May, 2016 | Pubmed ID: 27180357 A Disintegrin and Metalloprotease 10 (ADAM10) is a Central Regulator of Murine Liver Tissue Homeostasis Oncotarget. Apr, 2016 | Pubmed ID: 26942887 IL-6 Pathway in the Liver: From Physiopathology to Therapy Journal of Hepatology. Jun, 2016 | Pubmed ID: 26867490 Transgenic Analysis of the Leishmania MAP Kinase MPK10 Reveals an Auto-inhibitory Mechanism Crucial for Stage-regulated Activity and Parasite Viability PLoS Pathogens. Sep, 2014 | Pubmed ID: 25232945 Polo-like Kinase 2, a Novel ADAM17 Signaling Component, Regulates Tumor Necrosis Factor α Ectodomain Shedding The Journal of Biological Chemistry. Jan, 2014 | Pubmed ID: 24338472 Oncogenic Deletion Mutants of Gp130 Signal from Intracellular Compartments Journal of Cell Science. Jan, 2014 | Pubmed ID: 24213527 Hepatocytes Contribute to Immune Regulation in the Liver by Activation of the Notch Signaling Pathway in T Cells Journal of Immunology (Baltimore, Md. : 1950). Dec, 2013 | Pubmed ID: 24140644 Short-term TNFα Shedding is Independent of Cytoplasmic Phosphorylation or Furin Cleavage of ADAM17 Biochimica Et Biophysica Acta. Dec, 2013 | Pubmed ID: 24135057 Gp130 Activation is Regulated by D2-D3 Interdomain Connectivity The Biochemical Journal. Mar, 2013 | Pubmed ID: 23294003 Interleukin-6 Trans-signaling and Colonic Cancer Associated with Inflammatory Bowel Disease Digestive Diseases (Basel, Switzerland). 2012 | Pubmed ID: 23108305 The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-specific Features and Regulatory Mechanisms Structure (London, England : 1993). Oct, 2012 | Pubmed ID: 22884419 Tetraspanin15 Regulates Cellular Trafficking and Activity of the Ectodomain Sheddase ADAM10 Cellular and Molecular Life Sciences : CMLS. Sep, 2012 | Pubmed ID: 22446748 Adaptation of a 2D In-gel Kinase Assay to Trace Phosphotransferase Activities in the Human Pathogen Leishmania Donovani Journal of Proteomics. Aug, 2011 | Pubmed ID: 21443974 The Pro- and Anti-inflammatory Properties of the Cytokine Interleukin-6 Biochimica Et Biophysica Acta. May, 2011 | Pubmed ID: 21296109 Cyclosporin A Treatment of Leishmania Donovani Reveals Stage-specific Functions of Cyclophilins in Parasite Proliferation and Viability PLoS Neglected Tropical Diseases. Jun, 2010 | Pubmed ID: 20614016 Anchoring of FLT3 in the Endoplasmic Reticulum Alters Signaling Quality Blood. Apr, 2009 | Pubmed ID: 19204327 Cellular Inhibition of Protein Tyrosine Phosphatase 1B by Uncharged Thioxothiazolidinone Derivatives Chembiochem : a European Journal of Chemical Biology. Jan, 2007 | Pubmed ID: 17191286 Design and Biological Evaluation of Linear and Cyclic Phosphopeptide Ligands of the N-terminal SH2 Domain of Protein Tyrosine Phosphatase SHP-1 Journal of Medicinal Chemistry. Mar, 2005 | Pubmed ID: 15743195 Flt3 Receptor Tyrosine Kinase As a Drug Target in Leukemia Current Pharmaceutical Design. 2004 | Pubmed ID: 15180525 Functional Significance of Novel Neurotrophin-1/B Cell-stimulating Factor-3 (cardiotrophin-like Cytokine) for Human Myeloma Cell Growth and Survival British Journal of Haematology. Dec, 2003 | Pubmed ID: 14632778 مورين الكولين تعاني من نقص، تستكمل اثيونيني (الرفيق) النظام الغذائي النموذجي لإصابة الكبد المزمنة Jully Gogoi-Tiwari1, Julia Köhn-Gaone1, Corey Giles2, Dirk Schmidt-Arras3, Francis D. Gratte1,4, Caryn L. Elsegood1, Geoffrey W. McCaughan5,6,7, Grant A. Ramm8,9, John K. Olynyk10,11, Janina E.E. Tirnitz-Parker1,12 1School of Biomedical Sciences & Curtin Health Innovation Research Institute, Curtin University, 2School of Public Health & Curtin Health Innovation Research Institute, Curtin University, 3Institute of Biochemistry, Christian-Albrechts-University, 4School of Veterinary and Life Sciences, Murdoch University, 5Centenary Institute of Cancer Medicine and Cell Biology, The University of Sydney, 6Royal Prince Alfred Hospital, 7A.W. Morrow Gastroenterology and Liver Centre, 8QIMR Berghofer Medical Research Institute, 9Faculty of Medicine and Biomedical Sciences, The University of Queensland, 10Fiona Stanley and Fremantle Hospitals, 11School of Medical and Health Sciences, Edith Cowan University, 12School of Medicine and Pharmacology, University of Western Australia JoVE 56138 Biology
مورين الكولين تعاني من نقص، تستكمل اثيونيني (الرفيق) النظام الغذائي النموذجي لإصابة الكبد المزمنة Jully Gogoi-Tiwari1, Julia Köhn-Gaone1, Corey Giles2, Dirk Schmidt-Arras3, Francis D. Gratte1,4, Caryn L. Elsegood1, Geoffrey W. McCaughan5,6,7, Grant A. Ramm8,9, John K. Olynyk10,11, Janina E.E. Tirnitz-Parker1,12 1School of Biomedical Sciences & Curtin Health Innovation Research Institute, Curtin University, 2School of Public Health & Curtin Health Innovation Research Institute, Curtin University, 3Institute of Biochemistry, Christian-Albrechts-University, 4School of Veterinary and Life Sciences, Murdoch University, 5Centenary Institute of Cancer Medicine and Cell Biology, The University of Sydney, 6Royal Prince Alfred Hospital, 7A.W. Morrow Gastroenterology and Liver Centre, 8QIMR Berghofer Medical Research Institute, 9Faculty of Medicine and Biomedical Sciences, The University of Queensland, 10Fiona Stanley and Fremantle Hospitals, 11School of Medical and Health Sciences, Edith Cowan University, 12School of Medicine and Pharmacology, University of Western Australia JoVE 56138 Biology