Dorien Ward-van Oostwaard Department of Anatomy and Embryology Leiden University Medical Center Biography Publications Institution JoVE Articles Dorien Ward-van Oostwaard has not added a biography. If you are Dorien Ward-van Oostwaard and would like to personalize this page please email our Author Liaison for assistance. Publications Subtype-specific Promoter-driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in HiPSC-derived Cardiomyocytes European Heart Journal. Jan, 2017 | Pubmed ID: 28182242 A New HERG Allosteric Modulator Rescues Genetic and Drug-induced Long-QT Syndrome Phenotypes in Cardiomyocytes from Isogenic Pairs of Patient Induced Pluripotent Stem Cells EMBO Molecular Medicine. 09, 2016 | Pubmed ID: 27470144 Subtype-specific Promoter-driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in HiPSC-derived Cardiomyocytes European Heart Journal. Jun, 2016 | Pubmed ID: 27311732 Altered Calcium Handling and Increased Contraction Force in Human Embryonic Stem Cell Derived Cardiomyocytes Following Short Term Dexamethasone Exposure Biochemical and Biophysical Research Communications. Nov, 2015 | Pubmed ID: 26456652 Recessive Cardiac Phenotypes in Induced Pluripotent Stem Cell Models of Jervell and Lange-Nielsen Syndrome: Disease Mechanisms and Pharmacological Rescue Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25453094 BMP4 Promotes EMT and Mesodermal Commitment in Human Embryonic Stem Cells Via SLUG and MSX2 Stem Cells (Dayton, Ohio). Mar, 2014 | Pubmed ID: 24549638 Isogenic Human Pluripotent Stem Cell Pairs Reveal the Role of a KCNH2 Mutation in Long-QT Syndrome The EMBO Journal. Dec, 2013 | Pubmed ID: 24213244 Cardiomyocytes Derived from Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease Circulation. Jun, 2012 | Pubmed ID: 22647976 不同种族的人类胚胎干细胞的筛选标识 20 号染色体最小扩增子赋予生长优势。 Nature Biotechnology. Dec, 2011 | Pubmed ID: 22119741 NKX2-5(eGFP/w) HESCs 人类心脏祖细胞和心肌细胞的分离。 Nature Methods. Dec, 2011 | Pubmed ID: 22020065 Inhibition of ROCK Improves Survival of Human Embryonic Stem Cell-derived Cardiomyocytes After Dissociation Annals of the New York Academy of Sciences. Feb, 2010 | Pubmed ID: 20201886 Identification of Cell Surface Proteins for Antibody-based Selection of Human Embryonic Stem Cell-derived Cardiomyocytes Journal of Proteome Research. Mar, 2010 | Pubmed ID: 20088484 Improvement of Mouse Cardiac Function by HESC-derived Cardiomyocytes Correlates with Vascularity but Not Graft Size Stem Cell Research. Sep-Nov, 2009 | Pubmed ID: 19560991 Feeder-free Monolayer Cultures of Human Embryonic Stem Cells Express an Epithelial Plasma Membrane Protein Profile Stem Cells (Dayton, Ohio). Nov, 2008 | Pubmed ID: 18703662 Recombinant Vitronectin is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self-renewal Via Alphavbeta5 Integrin Stem Cells (Dayton, Ohio). Sep, 2008 | Pubmed ID: 18599809 Insulin Redirects Differentiation from Cardiogenic Mesoderm and Endoderm to Neuroectoderm in Differentiating Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Mar, 2008 | Pubmed ID: 18096723 Human Embryonic Stem Cell-derived Cardiomyocytes Survive and Mature in the Mouse Heart and Transiently Improve Function After Myocardial Infarction Stem Cell Research. Oct, 2007 | Pubmed ID: 19383383 Gene-specific Vulnerability to Imprinting Variability in Human Embryonic Stem Cell Lines Genome Research. Dec, 2007 | Pubmed ID: 17989250 Monitoring of Cell Therapy and Assessment of Cardiac Function Using Magnetic Resonance Imaging in a Mouse Model of Myocardial Infarction Nature Protocols. 2007 | Pubmed ID: 17947998 An Experimental Correction for Arginine-to-proline Conversion Artifacts in SILAC-based Quantitative Proteomics Nature Methods. Sep, 2007 | Pubmed ID: 17762871 Restriction Landmark Genome Scanning Identifies Culture-induced DNA Methylation Instability in the Human Embryonic Stem Cell Epigenome Human Molecular Genetics. May, 2007 | Pubmed ID: 17409196 Genome-wide Transcriptional Profiling of Human Embryonic Stem Cells Differentiating to Cardiomyocytes Stem Cells (Dayton, Ohio). Aug, 2006 | Pubmed ID: 16675594 A Quest for Human and Mouse Embryonic Stem Cell-specific Proteins Molecular & Cellular Proteomics : MCP. Jul, 2006 | Pubmed ID: 16600995 Human Embryonic Stem Cells: Towards Therapies for Cardiac Disease. Derivation of a Dutch Human Embryonic Stem Cell Line Reproductive Biomedicine Online. Oct, 2005 | Pubmed ID: 16274613 Increased Cardiomyocyte Differentiation from Human Embryonic Stem Cells in Serum-free Cultures Stem Cells (Dayton, Ohio). Jun-Jul, 2005 | Pubmed ID: 15917473 Regulation of Human Embryonic Stem Cell Differentiation by BMP-2 and Its Antagonist Noggin Journal of Cell Science. Mar, 2004 | Pubmed ID: 14996946 Differentiation of Human Embryonic Stem Cells to Cardiomyocytes: Role of Coculture with Visceral Endoderm-like Cells Circulation. Jun, 2003 | Pubmed ID: 12742992 使用多电极阵列(MEA)的人多能干细胞来源的心肌细胞(hPSC-CM)的电生理分析 Luca Sala1, Dorien Ward-van Oostwaard1, Leon G. J. Tertoolen1, Christine L Mummery1,2, Milena Bellin1 1Department of Anatomy and Embryology, Leiden University Medical Center, 2Department of Applied Stem Cell Technologies, University of Twente JoVE 55587 Developmental Biology
使用多电极阵列(MEA)的人多能干细胞来源的心肌细胞(hPSC-CM)的电生理分析 Luca Sala1, Dorien Ward-van Oostwaard1, Leon G. J. Tertoolen1, Christine L Mummery1,2, Milena Bellin1 1Department of Anatomy and Embryology, Leiden University Medical Center, 2Department of Applied Stem Cell Technologies, University of Twente JoVE 55587 Developmental Biology