Milena Bellin Department of Anatomy and Embryology Leiden University Medical Center Biography Publications Institution JoVE Articles Milena Bellin has not added a biography. If you are Milena Bellin and would like to personalize this page please email our Author Liaison for assistance. Publications Three-dimensional Cardiac Microtissues Composed of Cardiomyocytes and Endothelial Cells Co-differentiated from Human Pluripotent Stem Cells Development (Cambridge, England). Mar, 2017 | Pubmed ID: 28279973 Subtype-specific Promoter-driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in HiPSC-derived Cardiomyocytes European Heart Journal. Jan, 2017 | Pubmed ID: 28182242 Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5A Circulation. Arrhythmia and Electrophysiology. Nov, 2016 | Pubmed ID: 27784737 Integrating Cardiomyocytes from Human Pluripotent Stem Cells in Safety Pharmacology: Has the Time Come? British Journal of Pharmacology. Sep, 2016 | Pubmed ID: 27641943 A New HERG Allosteric Modulator Rescues Genetic and Drug-induced Long-QT Syndrome Phenotypes in Cardiomyocytes from Isogenic Pairs of Patient Induced Pluripotent Stem Cells EMBO Molecular Medicine. 09, 2016 | Pubmed ID: 27470144 Inherited Heart Disease - What Can We Expect from the Second Decade of Human IPS Cell Research? FEBS Letters. Aug, 2016 | Pubmed ID: 27391414 Subtype-specific Promoter-driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in HiPSC-derived Cardiomyocytes European Heart Journal. Jun, 2016 | Pubmed ID: 27311732 Stem Cells: The Cancer's Gone, but Did Chemotherapy Damage Your Heart? Nature Reviews. Cardiology. Jul, 2016 | Pubmed ID: 27226155 Human IPS Cell Models of Jervell and Lange-Nielsen Syndrome Rare Diseases (Austin, Tex.). 2015 | Pubmed ID: 26481773 Altered Calcium Handling and Increased Contraction Force in Human Embryonic Stem Cell Derived Cardiomyocytes Following Short Term Dexamethasone Exposure Biochemical and Biophysical Research Communications. Nov, 2015 | Pubmed ID: 26456652 Expansion and Patterning of Cardiovascular Progenitors Derived from Human Pluripotent Stem Cells Nature Biotechnology. Sep, 2015 | Pubmed ID: 26192318 Reply to Christ Et Al.: LQT1 and JLNS Phenotypes in HiPSC-derived Cardiomyocytes Are Due to KCNQ1 Mutations Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015 | Pubmed ID: 25795241 Functional Maturation of Human Pluripotent Stem Cell Derived Cardiomyocytes in Vitro--correlation Between Contraction Force and Electrophysiology Biomaterials. May, 2015 | Pubmed ID: 25771005 Immaturity of Human Stem-cell-derived Cardiomyocytes in Culture: Fatal Flaw or Soluble Problem? Stem Cells and Development. May, 2015 | Pubmed ID: 25583389 Recessive Cardiac Phenotypes in Induced Pluripotent Stem Cell Models of Jervell and Lange-Nielsen Syndrome: Disease Mechanisms and Pharmacological Rescue Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25453094 Isogenic Human Pluripotent Stem Cell Pairs Reveal the Role of a KCNH2 Mutation in Long-QT Syndrome The EMBO Journal. Dec, 2013 | Pubmed ID: 24213244 Induced Pluripotent Stem Cells: the New Patient? Nature Reviews. Molecular Cell Biology. Nov, 2012 | Pubmed ID: 23034453 Coronary Telangiectasia Associated with Hypertrophic Cardiomyopathy European Journal of Heart Failure. Dec, 2012 | Pubmed ID: 22869457 Modulation of HERG Potassium Channel Gating Normalizes Action Potential Duration Prolonged by Dysfunctional KCNQ1 Potassium Channel Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22745159 Dantrolene 救儿茶酚胺多形性室性心动过速病人特定干细胞模型中的致心律失常性 RYR2 缺陷。 EMBO Molecular Medicine. Dec, 2011 | Pubmed ID: 22174035 Patient-specific Induced Pluripotent Stem-cell Models for Long-QT Syndrome The New England Journal of Medicine. Oct, 2010 | Pubmed ID: 20660394 Mouse and Human Induced Pluripotent Stem Cells As a Source for Multipotent Isl1+ Cardiovascular Progenitors FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2010 | Pubmed ID: 19850773 Acidic Mammalian Chitinase in Dry Eye Conditions Cornea. Jul, 2009 | Pubmed ID: 19512904 CHIT1 and AMCase Expression in Human Gastric Mucosa: Correlation with Inflammation and Helicobacter Pylori Infection European Journal of Gastroenterology & Hepatology. Oct, 2009 | Pubmed ID: 19242357 Chitinase Levels in the Tears of Subjects with Ocular Allergies Cornea. Feb, 2008 | Pubmed ID: 18216571 Expression Profiling Characterization of Laminin Alpha-2 Positive MDC Biochemical and Biophysical Research Communications. Nov, 2006 | Pubmed ID: 17010933 使用多电极阵列(MEA)的人多能干细胞来源的心肌细胞(hPSC-CM)的电生理分析 Luca Sala1, Dorien Ward-van Oostwaard1, Leon G. J. Tertoolen1, Christine L Mummery1,2, Milena Bellin1 1Department of Anatomy and Embryology, Leiden University Medical Center, 2Department of Applied Stem Cell Technologies, University of Twente JoVE 55587 Developmental Biology
使用多电极阵列(MEA)的人多能干细胞来源的心肌细胞(hPSC-CM)的电生理分析 Luca Sala1, Dorien Ward-van Oostwaard1, Leon G. J. Tertoolen1, Christine L Mummery1,2, Milena Bellin1 1Department of Anatomy and Embryology, Leiden University Medical Center, 2Department of Applied Stem Cell Technologies, University of Twente JoVE 55587 Developmental Biology