Iman Osman Interdisciplinary Melanoma Cooperative Group Perlmutter Cancer Center Biography Publications Institution JoVE Articles Iman Osman has not added a biography. If you are Iman Osman and would like to personalize this page please email our Author Liaison for assistance. Publications The Histone Demethylase PHF8 Regulates TGFβ Signaling and Promotes Melanoma Metastasis Science Advances. Feb, 2022 | Pubmed ID: 35179962 Deep Learning and Pathomics Analyses Reveal Cell Nuclei As Important Features for Mutation Prediction of BRAF-Mutated Melanomas The Journal of Investigative Dermatology. Oct, 2021 | Pubmed ID: 34757067 Bacteroides Vulgatus and Bacteroides Dorei Predict Immune-related Adverse Events in Immune Checkpoint Blockade Treatment of Metastatic Melanoma Genome Medicine. 10, 2021 | Pubmed ID: 34641962 Targeting the Atf7ip-Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity Cancer Immunology Research. 11, 2021 | Pubmed ID: 34462284 Correction To: The Urgency of Utilizing COVID-19 Biospecimens for Research in the Heart of the Global Pandemic Journal of Translational Medicine. Jun, 2021 | Pubmed ID: 34082754 The "Great Debate" at Melanoma Bridge 2020: December, 5th, 2020 Journal of Translational Medicine. 04, 2021 | Pubmed ID: 33827575 Chronic Immune-Related Adverse Events Following Adjuvant Anti-PD-1 Therapy for High-risk Resected Melanoma JAMA Oncology. 05, 2021 | Pubmed ID: 33764387 Tumor Immunogenomic Signatures Improve a Prognostic Model of Melanoma Survival Journal of Translational Medicine. 02, 2021 | Pubmed ID: 33596955 Treatment with Therapeutic Anticoagulation is Not Associated with Immunotherapy Response in Advanced Cancer Patients Journal of Translational Medicine. 01, 2021 | Pubmed ID: 33516263 Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 01, 2021 | Pubmed ID: 33208341 Baseline Prognostic Nutritional Index and Changes in Pretreatment Body Mass Index Associate with Immunotherapy Response in Patients with Advanced Cancer Journal for Immunotherapy of Cancer. 11, 2020 | Pubmed ID: 33219093 Revisiting the Association Between Skin Toxicity and Better Response in Advanced Cancer Patients Treated with Immune Checkpoint Inhibitors Journal of Translational Medicine. 11, 2020 | Pubmed ID: 33176813 Preliminary Analysis of Distinct Clinical and Biologic Features of Bone Metastases in Melanoma Melanoma Research. 10, 2020 | Pubmed ID: 32804707 The Urgency of Utilizing COVID-19 Biospecimens for Research in the Heart of the Global Pandemic Journal of Translational Medicine. 06, 2020 | Pubmed ID: 32487093 TERT, BRAF, and NRAS Mutational Heterogeneity Between Paired Primary and Metastatic Melanoma Tumors The Journal of Investigative Dermatology. 08, 2020 | Pubmed ID: 32087194 Melanoma Prognosis: Accuracy of the American Joint Committee on Cancer Staging Manual Eighth Edition Journal of the National Cancer Institute. 09, 2020 | Pubmed ID: 31977051 Functional Analysis of RPS27 Mutations and Expression in Melanoma Pigment Cell & Melanoma Research. 05, 2020 | Pubmed ID: 31663663 Relating the Gut Metagenome and Metatranscriptome to Immunotherapy Responses in Melanoma Patients Genome Medicine. 10, 2019 | Pubmed ID: 31597568 The Complex Relationship Between Body Mass Index and Response to Immune Checkpoint Inhibition in Metastatic Melanoma Patients Journal for Immunotherapy of Cancer. 08, 2019 | Pubmed ID: 31426863 Immunomodulatory Germline Variation Associated with the Development of Multiple Primary Melanoma (MPM) Scientific Reports. 07, 2019 | Pubmed ID: 31308438 Impact of Initial Stage on Metastatic Melanoma Survival Melanoma Research. 06, 2019 | Pubmed ID: 31026246 Autoimmune Genetic Risk Variants As Germline Biomarkers of Response to Melanoma Immune-checkpoint Inhibition Cancer Immunology, Immunotherapy : CII. Jun, 2019 | Pubmed ID: 30863922 Development of Novel Mutation-Specific Droplet Digital PCR Assays Detecting TERT Promoter Mutations in Tumor and Plasma Samples The Journal of Molecular Diagnostics : JMD. 03, 2019 | Pubmed ID: 30827467 Association Between Ki-67 Expression and Clinical Outcomes Among Patients with Clinically Node-negative, Thick Primary Melanoma Who Underwent Nodal Staging Journal of Surgical Oncology. Jul, 2018 | Pubmed ID: 29878361 Adjuvant NY-ESO-1 Vaccine Immunotherapy in High-risk Resected Melanoma: a Retrospective Cohort Analysis Journal for Immunotherapy of Cancer. 05, 2018 | Pubmed ID: 29773080 Baseline Antibody Profiles Predict Toxicity in Melanoma Patients Treated with Immune Checkpoint Inhibitors Journal of Translational Medicine. 04, 2018 | Pubmed ID: 29606147 Pre-metastatic Cancer Exosomes Induce Immune Surveillance by Patrolling Monocytes at the Metastatic Niche Nature Communications. 11, 2017 | Pubmed ID: 29105655 A Systems Biology Approach Identifies FUT8 As a Driver of Melanoma Metastasis Cancer Cell. 06, 2017 | Pubmed ID: 28609658 Outcomes in Melanoma Patients Treated with BRAF/MEK-Directed Therapy or Immune Checkpoint Inhibition Stratified by Clinical Trial Versus Standard of Care Oncology. 2017 | Pubmed ID: 28601879 Genetic Markers of Pigmentation Are Novel Risk Loci for Uveal Melanoma Scientific Reports. Aug, 2016 | Pubmed ID: 27499155 Constitutive Lck Activity Drives Sensitivity Differences Between CD8+ Memory T Cell Subsets Journal of Immunology (Baltimore, Md. : 1950). 07, 2016 | Pubmed ID: 27271569 De Novo Vs Nevus-Associated Melanomas: Differences in Associations With Prognostic Indicators and Survival Journal of the National Cancer Institute. 10, 2016 | Pubmed ID: 27235387 Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1 Scientific Reports. Mar, 2016 | Pubmed ID: 26964503 The Expression Quantitative Trait Loci in Immune Pathways and Their Effect on Cutaneous Melanoma Prognosis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 07, 2016 | Pubmed ID: 26733611 Identification of a Novel Pathogenic Germline KDR Variant in Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 05, 2016 | Pubmed ID: 26631613 Sensitivity of Plasma BRAFmutant and NRASmutant Cell-free DNA Assays to Detect Metastatic Melanoma in Patients with Low RECIST Scores and Non-RECIST Disease Progression Molecular Oncology. Jan, 2016 | Pubmed ID: 26440707 Phosphorylation of EIF2α Triggered by MTORC1 Inhibition and PP6C Activation is Required for Autophagy and is Aberrant in PP6C-mutated Melanoma Science Signaling. Mar, 2015 | Pubmed ID: 25759478 Genetic Associations of the Interleukin Locus at 1q32.1 with Clinical Outcomes of Cutaneous Melanoma Journal of Medical Genetics. Apr, 2015 | Pubmed ID: 25604082 RSK1 Activation Promotes Invasion in Nodular Melanoma The American Journal of Pathology. Mar, 2015 | Pubmed ID: 25579842 Melanoma Expression of Matrix Metalloproteinase-23 is Associated with Blunted Tumor Immunity and Poor Responses to Immunotherapy Journal of Translational Medicine. Dec, 2014 | Pubmed ID: 25491880 A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis Arman Alberto Sorin Shadaloey1,2, Alcida Karz1,2, Rana S. Moubarak1,2, Praveen Agrawal1,2, Grace Levinson1,2, Kevin Kleffman1,2, Orlando Aristizabal3,4, Iman Osman2,5, Youssef Z. Wadghiri3,4, Eva Hernando1,2 1Department of Pathology, NYU Grossman School of Medicine, 2Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, 3Department of Radiology, NYU Grossman School of Medicine, 4Preclinical Imaging Core, NYU Grossman School of Medicine, 5Ronald Perelman Department of Dermatology, NYU Grossman School of Medicine JoVE 63186 Cancer Research
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis Arman Alberto Sorin Shadaloey1,2, Alcida Karz1,2, Rana S. Moubarak1,2, Praveen Agrawal1,2, Grace Levinson1,2, Kevin Kleffman1,2, Orlando Aristizabal3,4, Iman Osman2,5, Youssef Z. Wadghiri3,4, Eva Hernando1,2 1Department of Pathology, NYU Grossman School of Medicine, 2Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, 3Department of Radiology, NYU Grossman School of Medicine, 4Preclinical Imaging Core, NYU Grossman School of Medicine, 5Ronald Perelman Department of Dermatology, NYU Grossman School of Medicine JoVE 63186 Cancer Research