J. Steven Alexander Molecular and Cellular Physiology Louisiana State University Health Sciences Center in Shreveport Biography Publications Institution JoVE Articles J. Steven Alexander has not added a biography. If you are J. Steven Alexander and would like to personalize this page please email our Author Liaison for assistance. Publications Three-dimensional Printing of Bioactive Hernia Meshes: In vitro Proof of Principle Surgery. Oct, 2016 | Pubmed ID: 27726915 Hydrogen Sulfide Metabolism Regulates Endothelial Solute Barrier Function Redox Biology. Oct, 2016 | Pubmed ID: 27552214 From Trash to Treasure: The Untapped Potential of Endothelial Microparticles in Neurovascular Diseases Pathophysiology : the Official Journal of the International Society for Pathophysiology. Aug, 2016 | Pubmed ID: 27531185 Sulforaphane Induces Neurovascular Protection Against a Systemic Inflammatory Challenge Via Both Nrf2-dependent and Independent Pathways Vascular Pharmacology. Oct, 2016 | Pubmed ID: 27401964 Substitution with Alternative Anti-TNFα Therapy (SAVANT)-Outcomes of a Crohn's Disease Cohort Undergoing Substitution Therapy with Certolizumab Inflammatory Bowel Diseases. Jun, 2016 | Pubmed ID: 27104819 1,25(OH)2D3 Induces Placental Vascular Smooth Muscle Cell Relaxation by Phosphorylation of Myosin Phosphatase Target Subunit 1Ser507: Potential Beneficial Effects of Vitamin D on Placental Vasculature in Humans Biology of Reproduction. May, 2016 | Pubmed ID: 27075619 "Microglial Nodules" and "newly Forming Lesions" May Be a Janus Face of Early MS Lesions; Implications from Virus-induced Demyelination, the Inside-Out Model BMC Neurology. Oct, 2015 | Pubmed ID: 26499989 Evidence for Nontraditional Lymphatics in the Choroid Investigative Ophthalmology & Visual Science. Feb, 2015 | Pubmed ID: 26241180 Dual Signals Underlying Diabetic Lymphatic Barrier Dysregulation Cardiovascular Research. Jul, 2015 | Pubmed ID: 25994173 Distinct Kinetics of Viral Replication, T Cell Infiltration, and Fibrosis in Three Phases of Myocarditis Following Theiler's Virus Infection Cellular Immunology. Nov-Dec, 2014 | Pubmed ID: 25460083 Preface of the Special Issue - "Africa" Pathophysiology : the Official Journal of the International Society for Pathophysiology. Sep, 2014 | Pubmed ID: 25236675 Bioinformatics Multivariate Analysis Determined a Set of Phase-specific Biomarker Candidates in a Novel Mouse Model for Viral Myocarditis Circulation. Cardiovascular Genetics. Aug, 2014 | Pubmed ID: 25031303 Photothermolysis of Lymphatic Endothelial Cells by Gold Nanoshell-mediated Hyperthermia Journal of Nanoscience and Nanotechnology. Jul, 2014 | Pubmed ID: 24758030 Improved Wound Healing of Postischemic Cutaneous Flaps with the Use of Bone Marrow-derived Stem Cells The Laryngoscope. Mar, 2014 | Pubmed ID: 23818296 Role of Chymase in Preeclampsia Current Vascular Pharmacology. Sep, 2013 | Pubmed ID: 24063379 VEGF-A Isoform Modulation in an Preclinical TNBS Model of Ulcerative Colitis: Protective Effects of a VEGF164b Therapy Journal of Translational Medicine. Sep, 2013 | Pubmed ID: 24020796 A Recombinant Inhibitory Isoform of Vascular Endothelial Growth Factor164/165 Aggravates Ischemic Brain Damage in a Mouse Model of Focal Cerebral Ischemia The American Journal of Pathology. Sep, 2013 | Pubmed ID: 23906811 Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-mediated Transport of HDL Cell Metabolism. May, 2013 | Pubmed ID: 23663736 Does Pelvic Mesh Treated with Phosphorylcholine Improve Outcomes? An Early Experience European Journal of Obstetrics, Gynecology, and Reproductive Biology. Apr, 2013 | Pubmed ID: 23280282 Acute Carbonyl Stress Induces Occludin Glycation and Brain Microvascular Endothelial Barrier Dysfunction: Role for Glutathione-dependent Metabolism of Methylglyoxal Free Radical Biology & Medicine. Jan, 2013 | Pubmed ID: 23108103 Enhancing the Adhesion of Hematopoietic Precursor Cell Integrins with Hydrogen Peroxide Increases Recruitment Within Murine Gut Cell Transplantation. 2013 | Pubmed ID: 22889470 Immunopathological Patterns from EAE and Theiler's Virus Infection: Is Multiple Sclerosis a Homogenous 1-stage or Heterogenous 2-stage Disease? Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013 | Pubmed ID: 22633747 Angiopoietins As Promising Biomarkers and Potential Therapeutic Targets in Brain Injury Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013 | Pubmed ID: 22633746 Introduction: Brain Injury Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013 | Pubmed ID: 22503573 Emerging Roles of Endothelial Cells in Multiple Sclerosis Pathophysiology and Therapy Neurological Research. Oct, 2012 | Pubmed ID: 22828184 Plasma Ubiquitin-proteasome System Profile in Patients with Multiple Sclerosis: Correlation with Clinical Features, Neuroimaging, and Treatment with Interferon-beta-1b Neurological Research. Jul, 2012 | Pubmed ID: 22709658 Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis International Journal of Cell Biology. 2012 | Pubmed ID: 22505936 Rapamycin Inhibits Lymphatic Endothelial Cell Tube Formation by Downregulating Vascular Endothelial Growth Factor Receptor 3 Protein Expression Neoplasia (New York, N.Y.). Mar, 2012 | Pubmed ID: 22496622 Interferon-beta-1b Protects Against Multiple Sclerosis-induced Endothelial Cells Apoptosis Frontiers in Bioscience (Elite Edition). Jan, 2012 | Pubmed ID: 22201961 Gliovascular and Cytokine Interactions Modulate Brain Endothelial Barrier in Vitro Journal of Neuroinflammation. Nov, 2011 | Pubmed ID: 22112345 Synergistic Effect of Resveratrol and Quercetin Released from Drug-eluting Polymer Coatings for Endovascular Devices Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Nov, 2011 | Pubmed ID: 21948767 Cryptotanshinone Inhibits Lymphatic Endothelial Cell Tube Formation by Suppressing VEGFR-3/ERK and Small GTPase Pathways Cancer Prevention Research (Philadelphia, Pa.). Dec, 2011 | Pubmed ID: 21881029 Analysis of Endothelial Barrier Function in Vitro Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21874457 Complement in Neurobiology Frontiers in Bioscience (Landmark Edition). Jun, 2011 | Pubmed ID: 21622213 The Effects of High Dose Interferon-β1a on Plasma Microparticles: Correlation with MRI Parameters Journal of Neuroinflammation. May, 2011 | Pubmed ID: 21554694 Role of the Endothelium in Inflammatory Bowel Diseases World Journal of Gastroenterology. Feb, 2011 | Pubmed ID: 21350707 Selectin-mediated Recruitment of Bone Marrow Stromal Cells in the Postischemic Cerebral Microvasculature Stroke; a Journal of Cerebral Circulation. Mar, 2011 | Pubmed ID: 21257828 Multiple Sclerosis and Cerebral Endothelial Dysfunction: Mechanisms Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2011 | Pubmed ID: 20663648 Murine RVEGF164b, an Inhibitory VEGF Reduces VEGF-A-dependent Endothelial Proliferation and Barrier Dysfunction Microcirculation (New York, N.Y. : 1994). Oct, 2010 | Pubmed ID: 21040119 Emerging Roles of Lymphatics in Inflammatory Bowel Disease Annals of the New York Academy of Sciences. Oct, 2010 | Pubmed ID: 20961310 VEGF₁₆₄ Differentially Regulates Neutrophil and T Cell Adhesion Through ItgaL- and ItgaM-dependent Mechanisms American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2010 | Pubmed ID: 20884890 Analysis of in Vitro Transfection by Sonoporation Using Cationic and Neutral Microbubbles Ultrasound in Medicine & Biology. Nov, 2010 | Pubmed ID: 20800945 Elevated Plasma Chymotrypsin-like Protease (chymase) Activity in Women with Preeclampsia Hypertension in Pregnancy. 2010 | Pubmed ID: 20670150 Induction of Neuro-protective/regenerative Genes in Stem Cells Infiltrating Post-ischemic Brain Tissue Experimental & Translational Stroke Medicine. May, 2010 | Pubmed ID: 20509949 Alemtuzumab and Multiple Sclerosis: Therapeutic Application Expert Opinion on Biological Therapy. Mar, 2010 | Pubmed ID: 20095876 Editorial: Lymphatic Vessel Functions in Health and Disease Pathophysiology : the Official Journal of the International Society for Pathophysiology. Sep, 2010 | Pubmed ID: 20005084 Angiopoietin-2 in Experimental Colitis Inflammatory Bowel Diseases. Jun, 2010 | Pubmed ID: 19902545 Potential Roles of Cell-derived Microparticles in Ischemic Brain Disease Neurological Research. Oct, 2009 | Pubmed ID: 19723448 Chymotrypsin-like Protease (chymase) Mediates Endothelial Activation by Factors Derived from Preeclamptic Placentas Reproductive Sciences (Thousand Oaks, Calif.). Sep, 2009 | Pubmed ID: 19494363 Placenta-derived Chymotrypsin-like Protease (CLP) Disturbs Endothelial Junctional Structure in Preeclampsia Reproductive Sciences (Thousand Oaks, Calif.). May, 2009 | Pubmed ID: 19126871 Isotope Tracing Enhancement of Chemiluminescence Assays for Nitric Oxide Research Biological Chemistry. Feb, 2009 | Pubmed ID: 19040352 Proteomic Analysis of Human Cerebral Endothelial Cells Activated by Glutamate/MK-801: Significance in Ischemic Stroke Injury Journal of Molecular Neuroscience : MN. Jun, 2009 | Pubmed ID: 18843451 Evidence of Platelet Activation in Multiple Sclerosis Journal of Neuroinflammation. Jun, 2008 | Pubmed ID: 18588683 NeuroAIDS: Characteristics and Diagnosis of the Neurological Complications of AIDS Molecular Diagnosis & Therapy. 2008 | Pubmed ID: 18288880 Combination Therapy with Interferon Beta-1a and Doxycycline in Multiple Sclerosis: an Open-label Trial Archives of Neurology. Feb, 2008 | Pubmed ID: 18071030 Clinical and Neuroimaging Correlates of Antiphospholipid Antibodies in Multiple Sclerosis: a Preliminary Study BMC Neurology. Oct, 2007 | Pubmed ID: 17945023 Proteomic Analysis of Human Cerebral Endothelial Cells Activated by Multiple Sclerosis Serum and IFNbeta-1b Journal of Molecular Neuroscience : MN. 2007 | Pubmed ID: 17873362 Inflammatory Cytokines Induce MAdCAM-1 in Murine Hepatic Endothelial Cells and Mediate Alpha-4 Beta-7 Integrin Dependent Lymphocyte Endothelial Adhesion in Vitro BMC Physiology. Sep, 2007 | Pubmed ID: 17868448 HIV Antiretroviral Drug Combination Induces Endothelial Mitochondrial Dysfunction and Reactive Oxygen Species Production, but Not Apoptosis Toxicology and Applied Pharmacology. Oct, 2007 | Pubmed ID: 17669453 Platelet-associated NAD(P)H Oxidase Contributes to the Thrombogenic Phenotype Induced by Hypercholesterolemia Free Radical Biology & Medicine. Jul, 2007 | Pubmed ID: 17561090 Evolving Therapies for Multiple Sclerosis International Review of Neurobiology. 2007 | Pubmed ID: 17531859 Cell-derived Microparticles and Exosomes in Neuroinflammatory Disorders International Review of Neurobiology. 2007 | Pubmed ID: 17531844 The Destructive Alliance: Interactions of Leukocytes, Cerebral Endothelial Cells, and the Immune Cascade in Pathogenesis of Multiple Sclerosis International Review of Neurobiology. 2007 | Pubmed ID: 17531835 CD40-CD40 Ligand Mediates the Recruitment of Leukocytes and Platelets in the Inflamed Murine Colon Gastroenterology. Mar, 2007 | Pubmed ID: 17324402 Multiple Sclerosis As a Vascular Disease Neurological Research. Apr, 2006 | Pubmed ID: 16687046 Expression of Lymphatic Vascular Endothelial Hyaluronan Receptor-1 (LYVE-1) in the Human Placenta Lymphatic Research and Biology. 2006 | Pubmed ID: 16569201 Insulin Prevents Oxidant-induced Endothelial Cell Barrier Dysfunction Via Nitric Oxide-dependent Pathway Surgery. Jan, 2006 | Pubmed ID: 16364721 VEGF-A Stimulation of Leukocyte Adhesion to Colonic Microvascular Endothelium: Implications for Inflammatory Bowel Disease American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2006 | Pubmed ID: 16293653 Apolipoprotein A-IV Attenuates Oxidant-induced Apoptosis in Mitotic Competent, Undifferentiated Cells by Modulating Intracellular Glutathione Redox Balance American Journal of Physiology. Cell Physiology. Jan, 2006 | Pubmed ID: 16120654 Effects of Peroxynitrite and Superoxide Radicals on Endothelial Monolayer Permeability: Potential Role of Peroxynitrite in Preeclampsia Journal of the Society for Gynecologic Investigation. Dec, 2005 | Pubmed ID: 16325748 The Role of Alpha-4 Integrin in the Aetiology of Multiple Sclerosis: Current Knowledge and Therapeutic Implications CNS Drugs. 2005 | Pubmed ID: 16268663 Reversal of Experimental Colitis Disease Activity in Mice Following Administration of an Adenoviral IL-10 Vector Journal of Inflammation (London, England). Oct, 2005 | Pubmed ID: 16259632 DSS-induced Colitis is Exacerbated in STAT-6 Knockout Mice Inflammatory Bowel Diseases. Oct, 2005 | Pubmed ID: 16189417 Troglitazone, a PPAR-gamma Activator Prevents Endothelial Cell Adhesion Molecule Expression and Lymphocyte Adhesion Mediated by TNF-alpha BMC Physiology. Feb, 2005 | Pubmed ID: 15694007 Near-infrared Spectroscopy: a Tool to Monitor Cerebral Hemodynamic and Metabolic Changes After Cardiac Arrest in Rats Resuscitation. Nov, 2004 | Pubmed ID: 15531074 Deficit Di MMP-9 Migliora La Ferita a Collagenasi-indotta Di Emorragia E Cervello Intracerebrale Nel Topo Mutante Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Oct, 2004 | Pubmed ID: 15529013 Cerebral Cortical Aquaporin-4 Expression in Brain Edema Following Cardiac Arrest in Rats Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Oct, 2004 | Pubmed ID: 15466140 HIV-associated Dementia, Alzheimer's Disease, Multiple Sclerosis, and Schizophrenia: Gene Expression Review Journal of the Neurological Sciences. Sep, 2004 | Pubmed ID: 15450765 Pathogenesis of Brain and Spinal Cord Atrophy in Multiple Sclerosis Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. Jul, 2004 | Pubmed ID: 15228754 Effect of Ifenprodil, a Polyamine Site NMDA Receptor Antagonist, on Brain Edema Formation Following Asphyxial Cardiac Arrest in Rats Resuscitation. May, 2004 | Pubmed ID: 15135198 Citomegalovirus Umano Induce La Differenziazione Dei Monociti E Migrazione Come Una Strategia Per La Diffusione E La Persistenza Journal of Virology. May, 2004 | Pubmed ID: 15078925 CYP450 Dietary Inhibitors Attenuate TNF-alpha-stimulated Endothelial Molecule Expression and Leukocyte Adhesion American Journal of Physiology. Cell Physiology. Apr, 2004 | Pubmed ID: 15001427 Stereotactic Radiosurgery Using the Leksell Gamma Knife: Current Trends and Future Directives Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2004 | Pubmed ID: 14766419 Role of Prostaglandins in Maintaining Gastric Mucus-cell Permeability Against Acid Exposure The Journal of Laboratory and Clinical Medicine. Jan, 2004 | Pubmed ID: 14749685 Increased Disease Activity in ENOS-deficient Mice in Experimental Colitis Free Radical Biology & Medicine. Dec, 2003 | Pubmed ID: 14680690 Blood-brain Barrier Disruption in Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2003 | Pubmed ID: 14664465 Tight Junction Peptide Antagonists Enhance Neutrophil Trans-endothelial Chemotaxis Life Sciences. Aug, 2003 | Pubmed ID: 12875904 Gamma Knife Irradiation Increases Cerebral Endothelial Expression of Intercellular Adhesion Molecule 1 and E-selectin Neurosurgery. Jul, 2003 | Pubmed ID: 12823884 Serum from Patients with Multiple Sclerosis Downregulates Occludin and VE-cadherin Expression in Cultured Endothelial Cells Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2003 | Pubmed ID: 12814168 Randomized, Placebo-controlled, Double Blind, Crossover Design Trial of the Efficacy and Safety of Zestra for Women in Women with and Without Female Sexual Arousal Disorder Journal of Sex & Marital Therapy. 2003 | Pubmed ID: 12735087 The 3-hydroxy-3-methylglutaryl-CoA Reductase Inhibitor Pravastatin Reduces Disease Activity and Inflammation in Dextran-sulfate Induced Colitis The Journal of Pharmacology and Experimental Therapeutics. Apr, 2003 | Pubmed ID: 12649355 Transfection of IL-10 Expression Vectors into Endothelial Cultures Attenuates Alpha4beta7-dependent Lymphocyte Adhesion Mediated by MAdCAM-1 BMC Gastroenterology. Feb, 2003 | Pubmed ID: 12625840 Is the Gastric Epithelial Barrier Regulated by Cadherin Recruitment? European Journal of Gastroenterology & Hepatology. Dec, 2002 | Pubmed ID: 12468947 Devic Disease: Clinical Course, Pathophysiology, and Management Pathophysiology : the Official Journal of the International Society for Pathophysiology. Oct, 2002 | Pubmed ID: 12385963 Identification of an Occludin Cell Adhesion Recognition Sequence Inflammation. Aug, 2002 | Pubmed ID: 12184633 Extravascular Transport of Fluorescently Labeled Albumins in the Rat Mesentery Microcirculation (New York, N.Y. : 1994). Jul, 2002 | Pubmed ID: 12080415 Endothelial Junctional Protein Redistribution and Increased Monolayer Permeability in Human Umbilical Vein Endothelial Cells Isolated During Preeclampsia American Journal of Obstetrics and Gynecology. Feb, 2002 | Pubmed ID: 11854638 Mild Hypothermia Induced Before Cardiac Arrest Reduces Brain Edema Formation in Rats Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Feb, 2002 | Pubmed ID: 11825833 L'Assemblea e l'applicazione di "Shear Anelli ': A Novel endoteliale modello per Orbital, unidirezionale e periodica del fluido di flusso e lo stress di taglio Luke A. White1, Emily V. Stevenson1, J. Winny Yun1, Randa Eshaq1, Norman R. Harris1, David K. Mills2, Alireza Minagar3, Pierre-Olivier Couraud4, J. Steven Alexander1 1Molecular and Cellular Physiology, Louisiana State University Health Sciences Center in Shreveport, 2Biological Sciences, Louisiana Tech University, 3Neurology, Louisiana State University Health Sciences Center in Shreveport, 4Institut Cochin, Inserm U1016, Cnrs Umr8104, Université Paris Descartes Biology
L'Assemblea e l'applicazione di "Shear Anelli ': A Novel endoteliale modello per Orbital, unidirezionale e periodica del fluido di flusso e lo stress di taglio Luke A. White1, Emily V. Stevenson1, J. Winny Yun1, Randa Eshaq1, Norman R. Harris1, David K. Mills2, Alireza Minagar3, Pierre-Olivier Couraud4, J. Steven Alexander1 1Molecular and Cellular Physiology, Louisiana State University Health Sciences Center in Shreveport, 2Biological Sciences, Louisiana Tech University, 3Neurology, Louisiana State University Health Sciences Center in Shreveport, 4Institut Cochin, Inserm U1016, Cnrs Umr8104, Université Paris Descartes Biology