Pierre-Olivier Couraud Institut Cochin, Inserm U1016, Cnrs Umr8104 Université Paris Descartes Biography Publications Institution JoVE Articles Pierre-Olivier Couraud has not added a biography. If you are Pierre-Olivier Couraud and would like to personalize this page please email our Author Liaison for assistance. Publications [Research Funding: a Bottleneck for Economic Growth] Medecine Sciences : M/S. 8-9, 2016 | Pubmed ID: 27615162 Methylphenidate-triggered ROS Generation Promotes Caveolae-mediated Transcytosis Via Rac1 Signaling and C-Src-dependent Caveolin-1 Phosphorylation in Human Brain Endothelial Cells Cellular and Molecular Life Sciences : CMLS. Jul, 2016 | Pubmed ID: 27376435 Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier International Journal of Molecular Sciences. 2016 | Pubmed ID: 27294916 Human T-Lymphotropic Virus Type 1-Induced Overexpression of Activated Leukocyte Cell Adhesion Molecule (ALCAM) Facilitates Trafficking of Infected Lymphocytes Through the Blood-Brain Barrier Journal of Virology. Aug, 2016 | Pubmed ID: 27252538 In vitro Models of the Blood-brain Barrier: An Overview of Commonly Used Brain Endothelial Cell Culture Models and Guidelines for Their Use Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2016 | Pubmed ID: 26868179 Transthyretin Participates in Beta-amyloid Transport from the Brain to the Liver--involvement of the Low-density Lipoprotein Receptor-related Protein 1? Scientific Reports. Feb, 2016 | Pubmed ID: 26837706 Early Alterations of Hedgehog Signaling Pathway in Vascular Endothelial Cells After Peripheral Nerve Injury Elicit Blood-nerve Barrier Disruption, Nerve Inflammation, and Neuropathic Pain Development Pain. Apr, 2016 | Pubmed ID: 26655733 Assessment of Electrophile Damage in a Human Brain Endothelial Cell Line Utilizing a Clickable Alkyne Analog of 2-chlorohexadecanal Free Radical Biology & Medicine. Jan, 2016 | Pubmed ID: 26577177 The Hunt for Brain Aβ Oligomers by Peripherally Circulating Multi-functional Nanoparticles: Potential Therapeutic Approach for Alzheimer Disease Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2016 | Pubmed ID: 26410276 Solid Lipid Nanoparticles As a Vehicle for Brain-targeted Drug Delivery: Two New Strategies of Functionalization with Apolipoprotein E Nanotechnology. Dec, 2015 | Pubmed ID: 26574295 Immuno-analysis of Microparticles: Probing at the Limits of Detection Scientific Reports. Nov, 2015 | Pubmed ID: 26553743 Serotype O18 Avian Pathogenic and Neonatal Meningitis Escherichia Coli Strains Employ Similar Pathogenic Strategies for the Onset of Meningitis Virulence. 2015 | Pubmed ID: 26407066 Inflammatory Response of Endothelial Cells to a Human Endogenous Retrovirus Associated with Multiple Sclerosis is Mediated by TLR4 International Immunology. Nov, 2015 | Pubmed ID: 25957268 Aryl Hydrocarbon Receptor Regulates CYP1B1 but Not ABCB1 and ABCG2 in HCMEC/D3 Human Cerebral Microvascular Endothelial Cells After TCDD Exposure Brain Research. Jul, 2015 | Pubmed ID: 25858487 Phenotypic Variation in Aicardi-Goutières Syndrome Explained by Cell-specific IFN-stimulated Gene Response and Cytokine Release Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25769924 Development of a Solvent-free Analytical Method for Paracetamol Quantitative Determination in Blood Brain Barrier in Vitro Model Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Apr, 2015 | Pubmed ID: 25734939 Vemurafenib Resistance Selects for Highly Malignant Brain and Lung-metastasizing Melanoma Cells Cancer Letters. May, 2015 | Pubmed ID: 25725450 Differential Permissivity of Human Cerebrovascular Endothelial Cells to Enterovirus Infection and Specificities of Serotype EV-A71 in Crossing an in Vitro Model of the Human Blood-brain Barrier The Journal of General Virology. Jul, 2015 | Pubmed ID: 25711966 Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium-dependent Transport Dynamics in Human Blood-brain Barrier Endothelial Cells The Journal of Pharmacology and Experimental Therapeutics. Apr, 2015 | Pubmed ID: 25670633 Astrocytes Facilitate Melanoma Brain Metastasis Via Secretion Of IL-23 The Journal of Pathology. May, 2015 | Pubmed ID: 25639230 Carrier-mediated Cocaine Transport at the Blood-brain Barrier As a Putative Mechanism in Addiction Liability The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Jan, 2015 | Pubmed ID: 25539501 Permeability of PEGylated Immunoarsonoliposomes Through in Vitro Blood Brain Barrier-medulloblastoma Co-culture Models for Brain Tumor Therapy Pharmaceutical Research. Mar, 2015 | Pubmed ID: 25236341 The Metastatic Microenvironment: Claudin-1 Suppresses the Malignant Phenotype of Melanoma Brain Metastasis International Journal of Cancer. Mar, 2015 | Pubmed ID: 25046141 In Vitro Modeling of the Neurovascular Environment by Coculturing Adult Human Brain Endothelial Cells with Human Neural Stem Cells PloS One. 2014 | Pubmed ID: 25187991 The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family The AAPS Journal. Nov, 2014 | Pubmed ID: 25155823 Edaravone Protects Against Methylglyoxal-induced Barrier Damage in Human Brain Endothelial Cells PloS One. 2014 | Pubmed ID: 25033388 Synthesis and in Vitro Evaluation of BBB Permeability, Tumor Cell Uptake, and Cytotoxicity of a Series of Carboranylporphyrin Conjugates Journal of Medicinal Chemistry. Aug, 2014 | Pubmed ID: 25029034 Nanoparticle Formulation Improves the Anticonvulsant Effect of Clonazepam on the Pentylenetetrazole-induced Seizures: Behavior and Electroencephalogram Journal of Pharmaceutical Sciences. Aug, 2014 | Pubmed ID: 24916334 The Cross-talk Between Canonical and Non-canonical Wnt-dependent Pathways Regulates P-glycoprotein Expression in Human Blood-brain Barrier Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2014 | Pubmed ID: 24896565 Pathogenic Neisseria Meningitidis Utilizes CD147 for Vascular Colonization Nature Medicine. Jul, 2014 | Pubmed ID: 24880614 Primary Angiitis of the Central Nervous System: Description of the First Fifty-two Adults Enrolled in the French Cohort of Patients with Primary Vasculitis of the Central Nervous System Arthritis & Rheumatology (Hoboken, N.J.). May, 2014 | Pubmed ID: 24782189 Oxidative and Pro-inflammatory Impact of Regular and Denicotinized Cigarettes on Blood Brain Barrier Endothelial Cells: is Smoking Reduced or Nicotine-free Products Really Safe? BMC Neuroscience. Apr, 2014 | Pubmed ID: 24755281 Endotoxin-induced Monocytic Microparticles Have Contrasting Effects on Endothelial Inflammatory Responses PloS One. 2014 | Pubmed ID: 24646764 CXCL1/CXCL8 (GROα/IL-8) in Human Diabetic Ketoacidosis Plasma Facilitates Leukocyte Recruitment to Cerebrovascular Endothelium in Vitro American Journal of Physiology. Endocrinology and Metabolism. May, 2014 | Pubmed ID: 24619879 Drug-induced Trafficking of P-glycoprotein in Human Brain Capillary Endothelial Cells As Demonstrated by Exposure to Mitomycin C PloS One. 2014 | Pubmed ID: 24505408 Instruction of Circulating Endothelial Progenitors in Vitro Towards Specialized Blood-brain Barrier and Arterial Phenotypes PloS One. 2014 | Pubmed ID: 24392113 The Wnt/planar Cell Polarity Signaling Pathway Contributes to the Integrity of Tight Junctions in Brain Endothelial Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2014 | Pubmed ID: 24346691 Paracrine Signalling of Inflammatory Cytokines from an in Vitro Blood Brain Barrier Model Upon Exposure to Polymeric Nanoparticles The Analyst. Mar, 2014 | Pubmed ID: 24195103 Temozolomide Down-regulates P-glycoprotein in Human Blood-brain Barrier Cells by Disrupting Wnt3 Signaling Cellular and Molecular Life Sciences : CMLS. Feb, 2014 | Pubmed ID: 23771630 Immature Mesenchymal Stem Cell-like Pericytes As Mediators of Immunosuppression in Human Malignant Glioma Journal of Neuroimmunology. Dec, 2013 | Pubmed ID: 24090655 Wnt Activation of Immortalized Brain Endothelial Cells As a Tool for Generating a Standardized Model of the Blood Brain Barrier in Vitro PloS One. 2013 | Pubmed ID: 23940549 Temporal Profile of Matrix Metalloproteinases and Their Inhibitors in a Human Endothelial Cell Culture Model of Cerebral Ischemia Cerebrovascular Diseases (Basel, Switzerland). 2013 | Pubmed ID: 23817219 Somatostatin Preserved Blood Brain Barrier Against Cytokine Induced Alterations: Possible Role in Multiple Sclerosis Biochemical Pharmacology. Aug, 2013 | Pubmed ID: 23770458 A Multi-system Approach Assessing the Interaction of Anticonvulsants with P-gp PloS One. 2013 | Pubmed ID: 23741405 Effects of Aggregatibacter Actinomycetemcomitans Leukotoxin on Endothelial Cells Microbial Pathogenesis. Aug-Sep, 2013 | Pubmed ID: 23665198 Targeting Endothelial CD146 Attenuates Neuroinflammation by Limiting Lymphocyte Extravasation to the CNS Scientific Reports. 2013 | Pubmed ID: 23595028 The HCMEC/D3 Cell Line As a Model of the Human Blood Brain Barrier Fluids and Barriers of the CNS. Mar, 2013 | Pubmed ID: 23531482 Overexpression of CD44 in Neural Precursor Cells Improves Trans-endothelial Migration and Facilitates Their Invasion of Perivascular Tissues in Vivo PloS One. 2013 | Pubmed ID: 23468987 Glial-cell-mediated Re-induction of the Blood-brain Barrier Phenotype in Brain Capillary Endothelial Cells: a Differential Gel Electrophoresis Study Proteomics. Apr, 2013 | Pubmed ID: 23436736 Terapia a Base Di Lipoproteine Ad Alta Densità Riduce Le Complicanze Emorragiche Associate a Trattamento Attivatore Tissutale Del Plasminogeno Nel Tratto Sperimentale Stroke; a Journal of Cerebral Circulation. Mar, 2013 | Pubmed ID: 23422087 The Angiogenic Gene Profile of Circulating Endothelial Progenitor Cells from Ischemic Stroke Patients Vascular Cell. 2013 | Pubmed ID: 23388410 Functional Expression of a Proton-coupled Organic Cation (H+/OC) Antiporter in Human Brain Capillary Endothelial Cell Line HCMEC/D3, a Human Blood-brain Barrier Model Fluids and Barriers of the CNS. Jan, 2013 | Pubmed ID: 23351963 TWEAK/Fn14 Pathway Modulates Properties of a Human Microvascular Endothelial Cell Model of Blood Brain Barrier Journal of Neuroinflammation. 2013 | Pubmed ID: 23320797 The Brain Microvascular Endothelium Supports T Cell Proliferation and Has Potential for Alloantigen Presentation PloS One. 2013 | Pubmed ID: 23320074 Cooperation Between β- and γ-cytoplasmic Actins in the Mechanical Regulation of Endothelial Microparticle Formation FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2013 | Pubmed ID: 23159932 Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line HCMEC/D3 As a Human Blood-brain Barrier Model Molecular Pharmaceutics. Jan, 2013 | Pubmed ID: 23137377 Immortalized Human Cerebral Microvascular Endothelial Cells Maintain the Properties of Primary Cells in an in Vitro Model of Immune Migration Across the Blood Brain Barrier Journal of Neuroscience Methods. Jan, 2013 | Pubmed ID: 23068604 Tight Junctions at the Blood Brain Barrier: Physiological Architecture and Disease-associated Dysregulation Fluids and Barriers of the CNS. Nov, 2012 | Pubmed ID: 23140302 Transcellular Targeting of Fiber- and Hexon-modified Adenovirus Vectors Across the Brain Microvascular Endothelial Cells in Vitro PloS One. 2012 | Pubmed ID: 23029348 Localization Microscopy (SPDM) Reveals Clustered Formations of P-glycoprotein in a Human Blood-brain Barrier Model PloS One. 2012 | Pubmed ID: 22984556 Uptake and Cytotoxicity of Citrate-coated Gold Nanospheres: Comparative Studies on Human Endothelial and Epithelial Cells Particle and Fibre Toxicology. Jul, 2012 | Pubmed ID: 22759355 Cell-penetrating Anti-GFAP VHH and Corresponding Fluorescent Fusion Protein VHH-GFP Spontaneously Cross the Blood-brain Barrier and Specifically Recognize Astrocytes: Application to Brain Imaging FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2012 | Pubmed ID: 22730440 CCL2 Disrupts the Adherens Junction: Implications for Neuroinflammation Laboratory Investigation; a Journal of Technical Methods and Pathology. Aug, 2012 | Pubmed ID: 22641100 Angiotensin II Facilitates Breast Cancer Cell Migration and Metastasis PloS One. 2012 | Pubmed ID: 22536420 Il Microambiente Metastatico: Fattori Solubili Brain-derived Alterano Il Fenotipo Maligno Delle Cellule Di Melanoma Cutaneo E Cervello-metastasizing International Journal of Cancer. Journal International Du Cancer. Dec, 2012 | Pubmed ID: 22447293 [Transendothelial Migration Through the Neurovascular Unit: "a Cup to Cross the Barrier"] Medecine Sciences : M/S. Feb, 2012 | Pubmed ID: 22377292 Expression and Localization of Claudins-3 and -12 in Transformed Human Brain Endothelium Fluids and Barriers of the CNS. Feb, 2012 | Pubmed ID: 22373538 The Involvement of a Na⁺- and Cl⁻-dependent Transporter in the Brain Uptake of Amantadine and Rimantadine Molecular Pharmaceutics. Apr, 2012 | Pubmed ID: 22352408 Guanine Nucleotide-binding Protein Gαi2: a New Partner of Claudin-5 That Regulates Tight Junction Integrity in Human Brain Endothelial Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2012 | Pubmed ID: 22333621 Lamotrigine is a Substrate for OCT1 in Brain Endothelial Cells Biochemical Pharmacology. Mar, 2012 | Pubmed ID: 22227272 Hepatitis C Virus Infects the Endothelial Cells of the Blood-brain Barrier Gastroenterology. Mar, 2012 | Pubmed ID: 22138189 Angiogenic Biomarkers Predict the Occurrence of Digital Ulcers in Systemic Sclerosis Annals of the Rheumatic Diseases. Mar, 2012 | Pubmed ID: 22085793 The Metastatic Microenvironment: Brain-residing Melanoma Metastasis and Dormant Micrometastasis International Journal of Cancer. Sep, 2012 | Pubmed ID: 22025079 Purine Receptors and Ca(2+) Signalling in the Human Blood-brain Barrier Endothelial Cell Line HCMEC/D3 Purinergic Signalling. Mar, 2012 | Pubmed ID: 21956217 A Differential Proteomic Approach Identifies Structural and Functional Components That Contribute to the Differentiation of Brain Capillary Endothelial Cells Journal of Proteomics. Dec, 2011 | Pubmed ID: 21982828 Invading Basement Membrane Matrix is Sufficient for MDA-MB-231 Breast Cancer Cells to Develop a Stable in Vivo Metastatic Phenotype PloS One. 2011 | Pubmed ID: 21858074 Insights into the Putative Catechin and Epicatechin Transport Across Blood-brain Barrier Food & Function. Jan, 2011 | Pubmed ID: 21773584 Insights into the Pathogenesis of Systemic Sclerosis Based on the Gene Expression Profile of Progenitor-derived Endothelial Cells Arthritis and Rheumatism. Nov, 2011 | Pubmed ID: 21769840 Functionalization with ApoE-derived Peptides Enhances the Interaction with Brain Capillary Endothelial Cells of Nanoliposomes Binding Amyloid-beta Peptide Journal of Biotechnology. Dec, 2011 | Pubmed ID: 21763360 Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels Molecular Pharmaceutics. Aug, 2011 | Pubmed ID: 21707071 Development of a Three-dimensional, All-human in Vitro Model of the Blood-brain Barrier Using Mono-, Co-, and Tri-cultivation Transwell Models Journal of Neuroscience Methods. Aug, 2011 | Pubmed ID: 21609734 Human Brain Endothelial Cells Are Responsive to Adenosine Receptor Activation Purinergic Signalling. Jun, 2011 | Pubmed ID: 21484089 Secreted Factors from Brain Endothelial Cells Maintain Glioblastoma Stem-like Cell Expansion Through the MTOR Pathway EMBO Reports. May, 2011 | Pubmed ID: 21460795 Differential Expression of the Bone and the Liver Tissue Non-specific Alkaline Phosphatase Isoforms in Brain Tissues Cell and Tissue Research. Mar, 2011 | Pubmed ID: 21191615 Tyrosine Phosphorylation of VE-cadherin and Claudin-5 is Associated with TGF-β1-induced Permeability of Centrally Derived Vascular Endothelium European Journal of Cell Biology. Apr, 2011 | Pubmed ID: 21168935 Uptake and Permeability Studies of BBB-targeting Immunoliposomes Using the HCMEC/D3 Cell Line European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Feb, 2011 | Pubmed ID: 21118722 Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood-brain Barrier Endothelial Cells in Vitro Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2011 | Pubmed ID: 21045812 Metabolic Acidosis Induced by Plasmodium Falciparum Intraerythrocytic Stages Alters Blood-brain Barrier Integrity Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2011 | Pubmed ID: 20683453 Evaluation of Soluble Junctional Adhesion Molecule-A As a Biomarker of Human Brain Endothelial Barrier Breakdown PloS One. Oct, 2010 | Pubmed ID: 21060661 Role of Astrocytic Leptin Receptor Subtypes on Leptin Permeation Across HCMEC/D3 Human Brain Endothelial Cells Journal of Neurochemistry. Dec, 2010 | Pubmed ID: 20977476 Plasmodium Falciparum Adhesion on Human Brain Microvascular Endothelial Cells Involves Transmigration-like Cup Formation and Induces Opening of Intercellular Junctions PLoS Pathogens. Jul, 2010 | Pubmed ID: 20686652 Matrix Metalloproteinase 2 (MMP-2) Degrades Soluble Vasculotropic Amyloid-beta E22Q and L34V Mutants, Delaying Their Toxicity for Human Brain Microvascular Endothelial Cells The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20576603 A Novel Vascular Targeting Strategy for Brain-derived Endothelial Cells Using a TCR Mimic Antibody Journal of Cellular Physiology. Nov, 2010 | Pubmed ID: 20506235 Design of Fluorescently Tagged Poly(alkyl Cyanoacrylate) Nanoparticles for Human Brain Endothelial Cell Imaging Chemical Communications (Cambridge, England). Apr, 2010 | Pubmed ID: 20449321 IL8 and CXCL13 Are Potent Chemokines for the Recruitment of Human Neural Precursor Cells Across Brain Endothelial Cells Journal of Neuroimmunology. Jun, 2010 | Pubmed ID: 20400187 Identification of Peptide Ligands for Targeting to the Blood-brain Barrier Pharmaceutical Research. Apr, 2010 | Pubmed ID: 20162339 Induced Secretion of Beta-hexosaminidase by Human Brain Endothelial Cells: a Novel Approach in Sandhoff Disease? Neurobiology of Disease. Mar, 2010 | Pubmed ID: 20005954 Immortalized Human Brain Endothelial Cell Line HCMEC/D3 As a Model of the Blood-brain Barrier Facilitates in Vitro Studies of Central Nervous System Infection by Cryptococcus Neoformans Eukaryotic Cell. Nov, 2009 | Pubmed ID: 19767445 Modulation of Blood-brain Barrier Permeability by Neutrophils: in Vitro and in Vivo Studies Brain Research. Nov, 2009 | Pubmed ID: 19728990 Peripheral Blood CD4+ T Lymphocytes from Multiple Sclerosis Patients Are Characterized by Higher PSGL-1 Expression and Transmigration Capacity Across a Human Blood-brain Barrier-derived Endothelial Cell Line Journal of Leukocyte Biology. Nov, 2009 | Pubmed ID: 19696154 Role of KCNMA1 Gene in Breast Cancer Invasion and Metastasis to Brain BMC Cancer. Jul, 2009 | Pubmed ID: 19640305 Meningococcal Type IV Pili Recruit the Polarity Complex to Cross the Brain Endothelium Science (New York, N.Y.). Jul, 2009 | Pubmed ID: 19520910 Expression of ADAM-17, TIMP-3 and Fractalkine in the Human Adult Brain Endothelial Cell Line, HCMEC/D3, Following Pro-inflammatory Cytokine Treatment Journal of Neuroimmunology. May, 2009 | Pubmed ID: 19324423 The Blood-brain Barrier in Brain Homeostasis and Neurological Diseases Biochimica Et Biophysica Acta. Apr, 2009 | Pubmed ID: 19061857 Expression and Transcriptional Regulation of ABC Transporters and Cytochromes P450 in HCMEC/D3 Human Cerebral Microvascular Endothelial Cells Biochemical Pharmacology. Mar, 2009 | Pubmed ID: 19041851 ABC Transporters, Cytochromes P450 and Their Main Transcription Factors: Expression at the Human Blood-brain Barrier Journal of Neurochemistry. Dec, 2008 | Pubmed ID: 19094056 JAM-L-mediated Leukocyte Adhesion to Endothelial Cells is Regulated in Cis by Alpha4beta1 Integrin Activation The Journal of Cell Biology. Dec, 2008 | Pubmed ID: 19064666 The Human Brain Endothelial Cell Line HCMEC/D3 As a Human Blood-brain Barrier Model for Drug Transport Studies Journal of Neurochemistry. Dec, 2008 | Pubmed ID: 19013850 Alteration of Blood-brain Barrier Integrity by Retroviral Infection PLoS Pathogens. Nov, 2008 | Pubmed ID: 19008946 Tissue-type Plasminogen Activator is a Regulator of Monocyte Diapedesis Through the Brain Endothelial Barrier Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008 | Pubmed ID: 18714030 Hyperosmotic Stress Induces Axl Activation and Cleavage in Cerebral Endothelial Cells Journal of Neurochemistry. Oct, 2008 | Pubmed ID: 18673450 Caveolin-1 Regulates Human Immunodeficiency Virus-1 Tat-induced Alterations of Tight Junction Protein Expression Via Modulation of the Ras Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008 | Pubmed ID: 18667611 Molecular Mechanism of Systemic Delivery of Neural Precursor Cells to the Brain: Assembly of Brain Endothelial Apical Cups and Control of Transmigration by CD44 Stem Cells (Dayton, Ohio). Jul, 2008 | Pubmed ID: 18450824 Pcbs and Tight Junction Expression Environmental Toxicology and Pharmacology. Mar, 2008 | Pubmed ID: 18438464 Simvastatin Protects Against Amyloid Beta and HIV-1 Tat-induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells Molecular Pharmacology. May, 2008 | Pubmed ID: 18276775 Effetti Differenziali Di Idrocortisone E TNFalpha Sulle Proteine Di Giunzione Stretta in Un Modello in Vitro Della Umana Barriera Sangue - Cervello The Journal of Physiology. Apr, 2008 | Pubmed ID: 18258663 Immortalized Human Brain Endothelial Cells and Flow-based Vascular Modeling: a Marriage of Convenience for Rational Neurovascular Studies Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2008 | Pubmed ID: 17609686 Regulation of Cerebral Endothelial Cell Morphology by Extracellular Calcium Physics in Medicine and Biology. Oct, 2007 | Pubmed ID: 17921584 [Functions of Prion Protein PrPc] Medecine Sciences : M/S. Aug-Sep, 2007 | Pubmed ID: 17875293 Human Blood-brain Barrier Disruption by Retroviral-infected Lymphocytes: Role of Myosin Light Chain Kinase in Endothelial Tight-junction Disorganization Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17675520 PECAM-1 Engagement Counteracts ICAM-1-induced Signaling in Brain Vascular Endothelial Cells Journal of Neurochemistry. Oct, 2007 | Pubmed ID: 17662049 Reactive Oxygen Species Alter Brain Endothelial Tight Junction Dynamics Via RhoA, PI3 Kinase, and PKB Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2007 | Pubmed ID: 17586731 A Functional in Vitro Model of Rat Blood-brain Barrier for Molecular Analysis of Efflux Transporters Brain Research. May, 2007 | Pubmed ID: 17434463 TAL-1/SCL and Its Partners E47 and LMO2 Up-regulate VE-cadherin Expression in Endothelial Cells Molecular and Cellular Biology. Apr, 2007 | Pubmed ID: 17242194 Junctional Expression of the Prion Protein PrPC by Brain Endothelial Cells: a Role in Trans-endothelial Migration of Human Monocytes Journal of Cell Science. Nov, 2006 | Pubmed ID: 17062642 Neisseria Meningitidis Infezione Delle Cellule Endoteliali Umane Interferisce Con La Trasmigrazione Dei Leucociti Impedendo La Formazione Di Strutture Endoteliali Docking The Journal of Cell Biology. May, 2006 | Pubmed ID: 16717131 [Endothelin-1, Angiotensin II and Cancer] Medecine Sciences : M/S. Apr, 2006 | Pubmed ID: 16597412 Invasion of Endothelial Cells by Neisseria Meningitidis Requires Cortactin Recruitment by a Phosphoinositide-3-kinase/Rac1 Signalling Pathway Triggered by the Lipo-oligosaccharide Journal of Cell Science. Aug, 2005 | Pubmed ID: 16076899 Rat Brain Endothelial Cell Lines for the Study of Blood-brain Barrier Permeability and Transport Functions Cellular and Molecular Neurobiology. Feb, 2005 | Pubmed ID: 15962508 Trans-inactivation of Receptor Tyrosine Kinases by Novel Angiotensin II AT2 Receptor-interacting Protein, ATIP The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15123706 Development and Characterization of Immortalized Cerebral Endothelial Cell Lines Methods in Molecular Medicine. 2003 | Pubmed ID: 12958432 Intracellular Domain of Brain Endothelial Intercellular Adhesion Molecule-1 is Essential for T Lymphocyte-mediated Signaling and Migration Journal of Immunology (Baltimore, Md. : 1950). Aug, 2003 | Pubmed ID: 12902516 JAML, a Novel Protein with Characteristics of a Junctional Adhesion Molecule, is Induced During Differentiation of Myeloid Leukemia Cells Blood. Nov, 2003 | Pubmed ID: 12869515 Changes in Cytoskeletal and Tight Junctional Proteins Correlate with Decreased Permeability Induced by Dexamethasone in Cultured Rat Brain Endothelial Cells Neuroscience Letters. Jun, 2003 | Pubmed ID: 12782340 Lymphocyte Migration into the Central Nervous System: Implication of ICAM-1 Signalling at the Blood-brain Barrier Vascular Pharmacology. Jun, 2002 | Pubmed ID: 12529926 Human Adipose Cells Express CD4, CXCR4, and CCR5 [corrected] Receptors: a New Target Cell Type for the Immunodeficiency Virus-1? FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2002 | Pubmed ID: 12153994 Lymphocyte Trafficking Through the Blood-brain Barrier is Dependent on Endothelial Cell Heterotrimeric G-protein Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2002 | Pubmed ID: 12153986 How Do Extracellular Pathogens Cross the Blood-brain Barrier? Trends in Microbiology. May, 2002 | Pubmed ID: 11973156 Microvilli-like Structures Are Associated with the Internalization of Virulent Capsulated Neisseria Meningitidis into Vascular Endothelial Cells Journal of Cell Science. Mar, 2002 | Pubmed ID: 11884522 Characterization of Genetically Modified Human Retinal Pigment Epithelial Cells Developed for in Vitro and Transplantation Studies Investigative Ophthalmology & Visual Science. Feb, 2002 | Pubmed ID: 11818403 L'Assemblea e l'applicazione di "Shear Anelli ': A Novel endoteliale modello per Orbital, unidirezionale e periodica del fluido di flusso e lo stress di taglio Luke A. White1, Emily V. Stevenson1, J. Winny Yun1, Randa Eshaq1, Norman R. Harris1, David K. Mills2, Alireza Minagar3, Pierre-Olivier Couraud4, J. Steven Alexander1 1Molecular and Cellular Physiology, Louisiana State University Health Sciences Center in Shreveport, 2Biological Sciences, Louisiana Tech University, 3Neurology, Louisiana State University Health Sciences Center in Shreveport, 4Institut Cochin, Inserm U1016, Cnrs Umr8104, Université Paris Descartes Biology
L'Assemblea e l'applicazione di "Shear Anelli ': A Novel endoteliale modello per Orbital, unidirezionale e periodica del fluido di flusso e lo stress di taglio Luke A. White1, Emily V. Stevenson1, J. Winny Yun1, Randa Eshaq1, Norman R. Harris1, David K. Mills2, Alireza Minagar3, Pierre-Olivier Couraud4, J. Steven Alexander1 1Molecular and Cellular Physiology, Louisiana State University Health Sciences Center in Shreveport, 2Biological Sciences, Louisiana Tech University, 3Neurology, Louisiana State University Health Sciences Center in Shreveport, 4Institut Cochin, Inserm U1016, Cnrs Umr8104, Université Paris Descartes Biology