James I. Mullins Department of Microbiology University of Washington Biography Publications Institution JoVE Articles James I. Mullins has not added a biography. If you are James I. Mullins and would like to personalize this page please email our Author Liaison for assistance. Publications How Often Does Treatment of Primary HIV Lead to Post-treatment Control? Antiviral Therapy. Apr, 2015 | Pubmed ID: 25906138 A Human Immune Data-informed Vaccine Concept Elicits Strong and Broad T-cell Specificities Associated with HIV-1 Control in Mice and Macaques Journal of Translational Medicine. 2015 | Pubmed ID: 25879820 In Vitro Activity of Dolutegravir Against Wild-type and Integrase Inhibitor-resistant HIV-2 Retrovirology. 2015 | Pubmed ID: 25808007 P21(WAF1/CIP1) RNA Expression in Highly HIV-1 Exposed, Uninfected Individuals PloS One. 2015 | Pubmed ID: 25746435 Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial PLoS Computational Biology. Feb, 2015 | Pubmed ID: 25646817 Performance of Commonly Used Genotypic Assays and Comparison with Phenotypic Assays of HIV-1 Coreceptor Tropism in Acutely HIV-1-infected Patients The Journal of Antimicrobial Chemotherapy. May, 2015 | Pubmed ID: 25608585 Host Genetic and Viral Determinants of HIV-1 RNA Set Point Among HIV-1 Seroconverters from Sub-saharan Africa Journal of Virology. Feb, 2015 | Pubmed ID: 25473042 Lack of Resistance to Integrase Inhibitors Among Antiretroviral-naive Subjects with Primary HIV-1 Infection, 2007-2013 Antiviral Therapy. 2015 | Pubmed ID: 24831260 Vaccine-induced Human Antibodies Specific for the Third Variable Region of HIV-1 Gp120 Impose Immune Pressure on Infecting Viruses EBioMedicine. Nov, 2014 | Pubmed ID: 25599085 Spontaneous Control of HIV-1 Viremia in a Subject with Protective HLA-B Plus HLA-C Alleles and HLA-C Associated Single Nucleotide Polymorphisms Journal of Translational Medicine. 2014 | Pubmed ID: 25477316 CD8 and CD4 Epitope Predictions in RV144: No Strong Evidence of a T-cell Driven Sieve Effect in HIV-1 Breakthrough Sequences from Trial Participants PloS One. 2014 | Pubmed ID: 25350851 HIV-1 Conserved Elements P24CE DNA Vaccine Induces Humoral Immune Responses with Broad Epitope Recognition in Macaques PloS One. 2014 | Pubmed ID: 25338098 HIV Latency. Proliferation of Cells with HIV Integrated into Cancer Genes Contributes to Persistent Infection Science (New York, N.Y.). Aug, 2014 | Pubmed ID: 25011556 An HIV Epidemic Model Based on Viral Load Dynamics: Value in Assessing Empirical Trends in HIV Virulence and Community Viral Load PLoS Computational Biology. Jun, 2014 | Pubmed ID: 24945322 Dendritic Cells Restore CD8+ T Cell Reactivity to Autologous HIV-1 Journal of Virology. Sep, 2014 | Pubmed ID: 24942586 HIV-1 Superinfection with a Triple-class Drug-resistant Strain in a Patient Successfully Controlled with Antiretroviral Treatment AIDS (London, England). Jul, 2014 | Pubmed ID: 24911350 Analysis of HLA A*02 Association with Vaccine Efficacy in the RV144 HIV-1 Vaccine Trial Journal of Virology. Aug, 2014 | Pubmed ID: 24829343 Validation of an Oligonucleotide Ligation Assay for Quantification of Human Immunodeficiency Virus Type 1 Drug-resistant Mutants by Use of Massively Parallel Sequencing Journal of Clinical Microbiology. Jul, 2014 | Pubmed ID: 24740080 Impact of Mutations in Highly Conserved Amino Acids of the HIV-1 Gag-p24 and Env-gp120 Proteins on Viral Replication in Different Genetic Backgrounds PloS One. 2014 | Pubmed ID: 24713822 The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-specific CD8⁺ T Cell Responses Virology. Feb, 2014 | Pubmed ID: 24503065 Altered Response Hierarchy and Increased T-cell Breadth Upon HIV-1 Conserved Element DNA Vaccination in Macaques PloS One. 2014 | Pubmed ID: 24465991 Variants in Host Viral Replication Cycle Genes Are Associated with Heterosexual HIV-1 Acquisition in Africans Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2014 | Pubmed ID: 24463784 HIV-1 Subtype C is Not Associated with Higher Risk of Heterosexual HIV-1 Transmission: a Multinational Study Among HIV-1 Serodiscordant Couples AIDS (London, England). Jan, 2014 | Pubmed ID: 24413311 Toll-like Receptor Polymorphism Associations with HIV-1 Outcomes Among Sub-Saharan Africans The Journal of Infectious Diseases. May, 2014 | Pubmed ID: 24325963 Increased Sequence Coverage Through Combined Targeting of Variant and Conserved Epitopes Correlates with Control of HIV Replication Journal of Virology. Jan, 2014 | Pubmed ID: 24227851 Adhesion and Fusion Efficiencies of Human Immunodeficiency Virus Type 1 (HIV-1) Surface Proteins Scientific Reports. 2013 | Pubmed ID: 24145278 Improved Detection of Rare HIV-1 Variants Using 454 Pyrosequencing PloS One. 2013 | Pubmed ID: 24098517 Quality Score Based Identification and Correction of Pyrosequencing Errors PloS One. 2013 | Pubmed ID: 24039850 Inferring Viral Population Structures Using Heteroduplex Mobility and DNA Sequence Analyses Journal of Virological Methods. Dec, 2013 | Pubmed ID: 23994080 Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls PLoS Pathogens. Jul, 2013 | Pubmed ID: 23935489 Factors Affecting Relative Fitness Measurements in Pairwise Competition Assays of Human Immunodeficiency Viruses Journal of Virological Methods. Dec, 2013 | Pubmed ID: 23933395 Selective Induction of CTL Helper Rather Than Killer Activity by Natural Epitope Variants Promotes Dendritic Cell-mediated HIV-1 Dissemination Journal of Immunology (Baltimore, Md. : 1950). Sep, 2013 | Pubmed ID: 23913962 Indel and Carryforward Correction (ICC): a New Analysis Approach for Processing 454 Pyrosequencing Data Bioinformatics (Oxford, England). Oct, 2013 | Pubmed ID: 23900188 Fitness Costs of Mutations at the HIV-1 Capsid Hexamerization Interface PloS One. 2013 | Pubmed ID: 23785468 Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design PloS One. 2013 | Pubmed ID: 23741326 Complex Patterns of Protease Inhibitor Resistance Among Antiretroviral Treatment-experienced HIV-2 Patients from Senegal: Implications for Second-line Therapy Antimicrobial Agents and Chemotherapy. Jun, 2013 | Pubmed ID: 23571535 HIV-1 P24(gag) Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice PloS One. 2013 | Pubmed ID: 23555935 HIV-1 Conserved-element Vaccines: Relationship Between Sequence Conservation and Replicative Capacity Journal of Virology. May, 2013 | Pubmed ID: 23468488 Human Immunodeficiency Viruses Appear Compartmentalized to the Female Genital Tract in Cross-sectional Analyses but Genital Lineages Do Not Persist over Time The Journal of Infectious Diseases. Apr, 2013 | Pubmed ID: 23315326 Plasma Viral Loads During Early HIV-1 Infection Are Similar in Subtype C- and Non-subtype C-infected African Seroconverters The Journal of Infectious Diseases. Apr, 2013 | Pubmed ID: 23315322 Coverage of Primary Mother-to-child HIV Transmission Isolates by Second-generation Broadly Neutralizing Antibodies AIDS (London, England). Jan, 2013 | Pubmed ID: 23296195 A Sensitive Real-time PCR Based Assay to Estimate the Impact of Amino Acid Substitutions on the Competitive Replication Fitness of Human Immunodeficiency Virus Type 1 in Cell Culture Journal of Virological Methods. Apr, 2013 | Pubmed ID: 23201292 An Increasing Proportion of Monotypic HIV-1 DNA Sequences During Antiretroviral Treatment Suggests Proliferation of HIV-infected Cells Journal of Virology. Feb, 2013 | Pubmed ID: 23175380 Partner Characteristics Predicting HIV-1 Set Point in Sexually Acquired HIV-1 Among African Seroconverters AIDS Research and Human Retroviruses. Jan, 2013 | Pubmed ID: 23061422 Three Main Mutational Pathways in HIV-2 Lead to High-level Raltegravir and Elvitegravir Resistance: Implications for Emerging HIV-2 Treatment Regimens PloS One. 2012 | Pubmed ID: 23028968 Increased HIV-1 Vaccine Efficacy Against Viruses with Genetic Signatures in Env V2 Nature. Oct, 2012 | Pubmed ID: 22960785 MRKAd5 HIV-1 Gag/Pol/Nef Vaccine-Induced T-Cell Responses Inadequately Predict Distance of Breakthrough HIV-1 Sequences to the Vaccine or Viral Load PloS One. 2012 | Pubmed ID: 22952672 Towards an HIV Cure: a Global Scientific Strategy Nature Reviews. Immunology. Aug, 2012 | Pubmed ID: 22814509 CTL Responses of High Functional Avidity and Broad Variant Cross-reactivity Are Associated with HIV Control PloS One. 2012 | Pubmed ID: 22238642 Is the Virulence of HIV Changing? A Meta-analysis of Trends in Prognostic Markers of HIV Disease Progression and Transmission AIDS (London, England). Jan, 2012 | Pubmed ID: 22089381 Genomewide Association Study for Determinants of HIV-1 Acquisition and Viral Set Point in HIV-1 Serodiscordant Couples with Quantified Virus Exposure PloS One. 2011 | Pubmed ID: 22174851 Definition of the Viral Targets of Protective HIV-1-specific T Cell Responses Journal of Translational Medicine. 2011 | Pubmed ID: 22152067 Phenotypic Susceptibility of HIV-2 to Raltegravir: Integrase Mutations Q148R and N155H Confer Raltegravir Resistance AIDS (London, England). Nov, 2011 | Pubmed ID: 21971360 HIV-2 Integrase Variation in Integrase Inhibitor-naïve Adults in Senegal, West Africa PloS One. 2011 | Pubmed ID: 21765953 CD39/adenosine Pathway is Involved in AIDS Progression PLoS Pathogens. Jul, 2011 | Pubmed ID: 21750674 Preparing for the Availability of a Partially Effective HIV Vaccine: Some Lessons from Other Licensed Vaccines Vaccine. Aug, 2011 | Pubmed ID: 21745523 Demographic Processes Affect HIV-1 Evolution in Primary Infection Before the Onset of Selective Processes Journal of Virology. Aug, 2011 | Pubmed ID: 21593162 Genital HIV-1 RNA Predicts Risk of Heterosexual HIV-1 Transmission Science Translational Medicine. Apr, 2011 | Pubmed ID: 21471433 Increased Breadth and Depth of Cytotoxic T Lymphocytes Responses Against HIV-1-B Nef by Inclusion of Epitope Variant Sequences PloS One. 2011 | Pubmed ID: 21464919 Viral Linkage in HIV-1 Seroconverters and Their Partners in an HIV-1 Prevention Clinical Trial PloS One. 2011 | Pubmed ID: 21399681 Genetic Impact of Vaccination on Breakthrough HIV-1 Sequences from the STEP Trial Nature Medicine. Mar, 2011 | Pubmed ID: 21358627 Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection PloS One. 2011 | Pubmed ID: 21283794 Mutation of HIV-1 Genomes in a Clinical Population Treated with the Mutagenic Nucleoside KP1461 PloS One. 2011 | Pubmed ID: 21264288 Preclinical Evaluation of HIV-1 Therapeutic Ex Vivo Dendritic Cell Vaccines Expressing Consensus Gag Antigens and Conserved Gag Epitopes Vaccine. Mar, 2011 | Pubmed ID: 21241732 Screening Low-frequency SNPS from Genome-wide Association Study Reveals a New Risk Allele for Progression to AIDS Journal of Acquired Immune Deficiency Syndromes (1999). Mar, 2011 | Pubmed ID: 21107268 HIV-1 Envelope Subregion Length Variation During Disease Progression PLoS Pathogens. 2010 | Pubmed ID: 21187897 Dendritic Cells Reveal a Broad Range of MHC Class I Epitopes for HIV-1 in Persons with Suppressed Viral Load on Antiretroviral Therapy PloS One. 2010 | Pubmed ID: 20886040 Comment on "The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men" Science Translational Medicine. Sep, 2010 | Pubmed ID: 20861507 Estimating the Impact of Plasma HIV-1 RNA Reductions on Heterosexual HIV-1 Transmission Risk PloS One. 2010 | Pubmed ID: 20856886 Viral Evolution and Escape During Acute HIV-1 Infection The Journal of Infectious Diseases. Oct, 2010 | Pubmed ID: 20846038 Amino-acid Co-variation in HIV-1 Gag Subtype C: HLA-mediated Selection Pressure and Compensatory Dynamics PloS One. 2010 | Pubmed ID: 20824187 Multiple-cohort Genetic Association Study Reveals CXCR6 As a New Chemokine Receptor Involved in Long-term Nonprogression to AIDS The Journal of Infectious Diseases. Sep, 2010 | Pubmed ID: 20704485 Genetic Analyses of HIV-1 Env Sequences Demonstrate Limited Compartmentalization in Breast Milk and Suggest Viral Replication Within the Breast That Increases with Mastitis Journal of Virology. Oct, 2010 | Pubmed ID: 20660189 DIVEIN: a Web Server to Analyze Phylogenies, Sequence Divergence, Diversity, and Informative Sites BioTechniques. May, 2010 | Pubmed ID: 20569214 Restriction of HIV-1 Genotypes in Breast Milk Does Not Account for the Population Transmission Genetic Bottleneck That Occurs Following Transmission PloS One. 2010 | Pubmed ID: 20422033 Virus-specific CD8+ T-cell Responses Better Define HIV Disease Progression Than HLA Genotype Journal of Virology. May, 2010 | Pubmed ID: 20147397 Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV-1 Disease Progression to Clinical AIDS The Journal of Infectious Diseases. Feb, 2010 | Pubmed ID: 20064070 Phylogenetic Analysis of Population-based and Deep Sequencing Data to Identify Coevolving Sites in the Nef Gene of HIV-1 Molecular Biology and Evolution. Apr, 2010 | Pubmed ID: 19955476 Conserved HIV-1 Epitopes Continuously Elicit Subdominant Cytotoxic T-lymphocyte Responses The Journal of Infectious Diseases. Dec, 2009 | Pubmed ID: 19909083 Evidence for Limited Genetic Compartmentalization of HIV-1 Between Lung and Blood PloS One. 2009 | Pubmed ID: 19759830 Fidelity of SNP Array Genotyping Using Epstein Barr Virus-transformed B-lymphocyte Cell Lines: Implications for Genome-wide Association Studies PloS One. 2009 | Pubmed ID: 19730697 Preinfection Human Immunodeficiency Virus (HIV)-specific Cytotoxic T Lymphocytes Failed to Prevent HIV Type 1 Infection from Strains Genetically Unrelated to Viruses in Long-term Exposed Partners Journal of Virology. Oct, 2009 | Pubmed ID: 19706711 HIV-1 Superinfection in the Antiretroviral Therapy Era: Are Seroconcordant Sexual Partners at Risk? PloS One. 2009 | Pubmed ID: 19479055 Increased Mutations in Env and Pol Suggest Greater HIV-1 Replication in Sputum-derived Viruses Compared with Blood-derived Viruses AIDS (London, England). May, 2009 | Pubmed ID: 19349849 Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response PLoS Pathogens. Apr, 2009 | Pubmed ID: 19343217 Monotypic Human Immunodeficiency Virus Type 1 Genotypes Across the Uterine Cervix and in Blood Suggest Proliferation of Cells with Provirus Journal of Virology. Jun, 2009 | Pubmed ID: 19339344 Rare HLA Drive Additional HIV Evolution Compared to More Frequent Alleles AIDS Research and Human Retroviruses. Mar, 2009 | Pubmed ID: 19327049 Emergence of Multiclass Drug-resistance in HIV-2 in Antiretroviral-treated Individuals in Senegal: Implications for HIV-2 Treatment in Resouce-limited West Africa Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2009 | Pubmed ID: 19143530 Viral Evolution and Escape During Primary Human Immunodeficiency Virus-1 Infection: Implications for Vaccine Design Current Opinion in HIV and AIDS. Jan, 2008 | Pubmed ID: 19372945 Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag PLoS Computational Biology. Nov, 2008 | Pubmed ID: 19023406 Evolution of CCR5 Use Before and During Coreceptor Switching Journal of Virology. Dec, 2008 | Pubmed ID: 18815295 Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point Journal of Virology. Sep, 2008 | Pubmed ID: 18596105 Comparison of Immunogen Designs That Optimize Peptide Coverage: Reply to Fischer Et Al PLoS Computational Biology. Jan, 2008 | Pubmed ID: 18463692 HLA Class I-driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load Journal of Virology. Jul, 2008 | Pubmed ID: 18434400 Male Genital Tract Compartmentalization of Human Immunodeficiency Virus Type 1 (HIV) AIDS Research and Human Retroviruses. Apr, 2008 | Pubmed ID: 18426336 HIV-1 Variation Before Seroconversion in Men Who Have Sex with Men: Analysis of Acute/early HIV Infection in the Multicenter AIDS Cohort Study The Journal of Infectious Diseases. Apr, 2008 | Pubmed ID: 18419538 Env Length and N-linked Glycosylation Following Transmission of Human Immunodeficiency Virus Type 1 Subtype B Viruses Virology. May, 2008 | Pubmed ID: 18314154 Increased Detection of HIV-specific T Cell Responses by Combination of Central Sequences with Comparable Immunogenicity AIDS (London, England). Feb, 2008 | Pubmed ID: 18301057 Persistence of HIV in Gut-associated Lymphoid Tissue Despite Long-term Antiretroviral Therapy The Journal of Infectious Diseases. Mar, 2008 | Pubmed ID: 18260759 Lack of Evidence for Changing Virulence of HIV-1 in North America PloS One. 2008 | Pubmed ID: 18253479 Broad and Gag-biased HIV-1 Epitope Repertoires Are Associated with Lower Viral Loads PloS One. 2008 | Pubmed ID: 18183304 Blood Monocytes Harbor HIV Type 1 Strains with Diversified Phenotypes Including Macrophage-specific CCR5 Virus The Journal of Infectious Diseases. Jan, 2008 | Pubmed ID: 18173363 Novel Cytotoxic T-lymphocyte Escape Mutation by a Three-amino-acid Insertion in the Human Immunodeficiency Virus Type 1 P6Pol and P6Gag Late Domain Associated with Drug Resistance Journal of Virology. Jan, 2008 | Pubmed ID: 17942528 HIV-1 Group M Conserved Elements Vaccine PLoS Pathogens. Nov, 2007 | Pubmed ID: 18052528 Recognition of HIV-1 Peptides by Host CTL is Related to HIV-1 Similarity to Human Proteins PloS One. 2007 | Pubmed ID: 17786195 Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-lymphocyte Epitopes: Fitness-balanced Escape Journal of Virology. Nov, 2007 | Pubmed ID: 17728222 HIV-1 over Time: Fitness Loss or Robustness Gain? Nature Reviews. Microbiology. Sep, 2007 | Pubmed ID: 17703224 HIV Type 1 Superinfection with a Dual-tropic Virus and Rapid Progression to AIDS: a Case Report Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Aug, 2007 | Pubmed ID: 17638203 Methods Used to Examine Compartmentalization of Viral Populations Between the Genital Tract and Peripheral Blood The Journal of Infectious Diseases. Aug, 2007 | Pubmed ID: 17597465 ViroBLAST: a Stand-alone BLAST Web Server for Flexible Queries of Multiple Databases and User's Datasets Bioinformatics (Oxford, England). Sep, 2007 | Pubmed ID: 17586542 HIV-specific Probabilistic Models of Protein Evolution PloS One. 2007 | Pubmed ID: 17551583 Reconstruction and Function of Ancestral Center-of-tree Human Immunodeficiency Virus Type 1 Proteins Journal of Virology. Aug, 2007 | Pubmed ID: 17537854 Prevalence and Genetic Diversity of HIV Type 1 Subtypes A and D in Women Attending Antenatal Clinics in Uganda AIDS Research and Human Retroviruses. May, 2007 | Pubmed ID: 17531003 Compensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation Within the Immunodominant HLA-B*5703-restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Aug, 2007 | Pubmed ID: 17507468 Decay of the HIV Reservoir in Patients Receiving Antiretroviral Therapy for Extended Periods: Implications for Eradication of Virus The Journal of Infectious Diseases. Jun, 2007 | Pubmed ID: 17492591 Coping with Viral Diversity in HIV Vaccine Design PLoS Computational Biology. Apr, 2007 | Pubmed ID: 17465674 Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations Science (New York, N.Y.). Mar, 2007 | Pubmed ID: 17363674 Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection Journal of Virology. May, 2007 | Pubmed ID: 17329342 Presenting Plasma HIV RNA Level and Rate of CD4 T-cell Decline JAMA. Feb, 2007 | Pubmed ID: 17327518 Extensive Intrasubtype Recombination in South African Human Immunodeficiency Virus Type 1 Subtype C Infections Journal of Virology. May, 2007 | Pubmed ID: 17314156 Control of Human Immunodeficiency Virus Type 1 is Associated with HLA-B*13 and Targeting of Multiple Gag-specific CD8+ T-cell Epitopes Journal of Virology. Apr, 2007 | Pubmed ID: 17251285 CD8+ T-cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load Nature Medicine. Jan, 2007 | Pubmed ID: 17173051 Comprehensive Epitope Analysis of Cross-clade Gag-specific T-cell Responses in Individuals with Early HIV-1 Infection in the US Epidemic Vaccine. Jan, 2007 | Pubmed ID: 17112643 Sources of Variation in Ancestral Sequence Reconstruction for HIV-1 Envelope Genes Evolutionary Bioinformatics Online. 2006 | Pubmed ID: 19455202 Differential Selection Pressure Exerted on HIV by CTL Targeting Identical Epitopes but Restricted by Distinct HLA Alleles from the Same HLA Supertype Journal of Immunology (Baltimore, Md. : 1950). Oct, 2006 | Pubmed ID: 16982909 Selection on the Human Immunodeficiency Virus Type 1 Proteome Following Primary Infection Journal of Virology. Oct, 2006 | Pubmed ID: 16973556 Evolution of Intrahost HIV-1 Genetic Diversity During Chronic Infection Evolution; International Journal of Organic Evolution. Jun, 2006 | Pubmed ID: 16892967 Large-scale Amplification, Cloning and Sequencing of Near Full-length HIV-1 Subtype C Genomes Journal of Virological Methods. Sep, 2006 | Pubmed ID: 16701907 A Reliable Phenotype Predictor for Human Immunodeficiency Virus Type 1 Subtype C Based on Envelope V3 Sequences Journal of Virology. May, 2006 | Pubmed ID: 16641263 Density-dependent Decay in HIV-1 Dynamics Journal of Acquired Immune Deficiency Syndromes (1999). Mar, 2006 | Pubmed ID: 16540927 Fitness Cost of Escape Mutations in P24 Gag in Association with Control of Human Immunodeficiency Virus Type 1 Journal of Virology. Apr, 2006 | Pubmed ID: 16537629 Human Immunodeficiency Virus Type 1 Env Evolves Toward Ancestral States Upon Transmission to a New Host Journal of Virology. Feb, 2006 | Pubmed ID: 16439520 Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope Nature Immunology. Feb, 2006 | Pubmed ID: 16388312 Waiting Times for the Appearance of Cytotoxic T-lymphocyte Escape Mutants in Chronic HIV-1 Infection Virology. Mar, 2006 | Pubmed ID: 16387340 Control of Human Immunodeficiency Virus Replication by Cytotoxic T Lymphocytes Targeting Subdominant Epitopes Nature Immunology. Feb, 2006 | Pubmed ID: 16369537 Sampling Designs for HIV Molecular Epidemiology with Application to Honduras AIDS Research and Human Retroviruses. Nov, 2005 | Pubmed ID: 16386105 HIV-infected Individuals Receiving Effective Antiviral Therapy for Extended Periods of Time Continually Replenish Their Viral Reservoir The Journal of Clinical Investigation. Nov, 2005 | Pubmed ID: 16276421 Nef Induces Multiple Genes Involved in Cholesterol Synthesis and Uptake in Human Immunodeficiency Virus Type 1-infected T Cells Journal of Virology. Aug, 2005 | Pubmed ID: 16014965 Evidence That Low-level Viremias During Effective Highly Active Antiretroviral Therapy Result from Two Processes: Expression of Archival Virus and Replication of Virus Journal of Virology. Aug, 2005 | Pubmed ID: 16014925 Changes in Human Immunodeficiency Virus Type 1 Fitness and Genetic Diversity During Disease Progression Journal of Virology. Jul, 2005 | Pubmed ID: 15994794 Preferential Detection of HIV Subtype C' over Subtype A in Cervical Cells from a Dually Infected Woman AIDS (London, England). Jun, 2005 | Pubmed ID: 15905685 No Evidence for Recombination Between HIV Type 1 and HIV Type 2 Within the Envelope Region in Dually Seropositive Individuals from Senegal AIDS Research and Human Retroviruses. Sep, 2004 | Pubmed ID: 15585083 Longitudinal and Cross-sectional Studies of HIV-1 RNA and DNA Loads in Blood and the Female Genital Tract European Journal of Obstetrics, Gynecology, and Reproductive Biology. Dec, 2004 | Pubmed ID: 15541862 Molecular Clock-like Evolution of Human Immunodeficiency Virus Type 1 Virology. Nov, 2004 | Pubmed ID: 15476878 Pervasive Genomic Recombination of HIV-1 in Vivo Genetics. Aug, 2004 | Pubmed ID: 15342499 Immunogen Sequence: the Fourth Tier of AIDS Vaccine Design Expert Review of Vaccines. Aug, 2004 | Pubmed ID: 15285713 Compartmentalization of Human Immunodeficiency Virus Type 1 Between Blood Monocytes and CD4+ T Cells During Infection Journal of Virology. Aug, 2004 | Pubmed ID: 15254161 Persistence of Low Levels of Simian Immunodeficiency Virus in Macaques That Were Transiently Viremic by Conventional Testing Virology. Jun, 2004 | Pubmed ID: 15193917 Differences in the Expressed HLA Class I Alleles Effect the Differential Clustering of HIV Type 1-specific T Cell Responses in Infected Chinese and Caucasians AIDS Research and Human Retroviruses. May, 2004 | Pubmed ID: 15186531 Clinical and Immunological Impact of HIV Envelope V3 Sequence Variation After Starting Initial Triple Antiretroviral Therapy AIDS (London, England). Mar, 2004 | Pubmed ID: 15090786 Influence of Random Genetic Drift on Human Immunodeficiency Virus Type 1 Env Evolution During Chronic Infection Genetics. Mar, 2004 | Pubmed ID: 15082537 Dual HIV-1 Infection Associated with Rapid Disease Progression Lancet. Feb, 2004 | Pubmed ID: 14987889 Improved Coreceptor Usage Prediction and Genotypic Monitoring of R5-to-X4 Transition by Motif Analysis of Human Immunodeficiency Virus Type 1 Env V3 Loop Sequences Journal of Virology. Dec, 2003 | Pubmed ID: 14645592 Importance and Detection of Virus Reservoirs and Compartments of HIV Infection Current Opinion in Microbiology. Aug, 2003 | Pubmed ID: 12941414 Molecular Epidemiology of Dual HIV-1/HIV-2 Seropositive Adults from Senegal, West Africa AIDS Research and Human Retroviruses. Jul, 2003 | Pubmed ID: 12908935 Potential Impact of Recombination on Sitewise Approaches for Detecting Positive Natural Selection Genetical Research. Apr, 2003 | Pubmed ID: 12872913 Enhanced Detection of Human Immunodeficiency Virus Type 1-specific T-cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences Journal of Virology. Jul, 2003 | Pubmed ID: 12805431 Predicting Demographic Group Structures Based on DNA Sequence Data Molecular Biology and Evolution. Jul, 2003 | Pubmed ID: 12777527 Persistence of Extraordinarily Low Levels of Genetically Homogeneous Human Immunodeficiency Virus Type 1 in Exposed Seronegative Individuals Journal of Virology. Jun, 2003 | Pubmed ID: 12743268 Multiple Viral Genetic Analyses Detect Low-level Human Immunodeficiency Virus Type 1 Replication During Effective Highly Active Antiretroviral Therapy Journal of Virology. May, 2003 | Pubmed ID: 12719565 Evolutionary Indicators of Human Immunodeficiency Virus Type 1 Reservoirs and Compartments Journal of Virology. May, 2003 | Pubmed ID: 12692259 Consensus and Ancestral State HIV Vaccines Science (New York, N.Y.). Mar, 2003 | Pubmed ID: 12624248 Genetic Characterization of Rebounding Human Immunodeficiency Virus Type 1 in Plasma During Multiple Interruptions of Highly Active Antiretroviral Therapy Journal of Virology. Mar, 2003 | Pubmed ID: 12584346 Cellular Gene Expression Upon Human Immunodeficiency Virus Type 1 Infection of CD4(+)-T-cell Lines Journal of Virology. Jan, 2003 | Pubmed ID: 12502855 Virus Population Homogenization Following Acute Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Dec, 2002 | Pubmed ID: 12414937 Selection for Human Immunodeficiency Virus Type 1 Recombinants in a Patient with Rapid Progression to AIDS Journal of Virology. Nov, 2002 | Pubmed ID: 12368309 Human Immunodeficiency Virus Type 1 Bound to B Cells: Relationship to Virus Replicating in CD4+ T Cells and Circulating in Plasma Journal of Virology. Sep, 2002 | Pubmed ID: 12163605 Molecular Cloning and Characterization of Antheraea Mylitta Cytoplasmic Polyhedrosis Virus Genome Segment 9 The Journal of General Virology. Jun, 2002 | Pubmed ID: 12029164 Equal Plasma Viral Loads Predict a Similar Rate of CD4+ T Cell Decline in Human Immunodeficiency Virus (HIV) Type 1- and HIV-2-infected Individuals from Senegal, West Africa The Journal of Infectious Diseases. Apr, 2002 | Pubmed ID: 11920314 Site-directed Mutagenesis Facilitated by DpnI Selection on Hemimethylated DNA Methods in Molecular Biology (Clifton, N.J.). 2002 | Pubmed ID: 11768966 Evidence for Human Immunodeficiency Virus Type 1 Replication in Vivo in CD14(+) Monocytes and Its Potential Role As a Source of Virus in Patients on Highly Active Antiretroviral Therapy Journal of Virology. Jan, 2002 | Pubmed ID: 11752161 Curiously Modern DNA for a "250 Million-year-old" Bacterium Journal of Molecular Evolution. Jan, 2002 | Pubmed ID: 11734907 Pairwise Growth Competition Assay for Determining the Replication Fitness of Human Immunodeficiency Viruses Siriphan Manocheewa1, Erinn C. Lanxon-Cookson1, Yi Liu1, J. Victor Swain1, Jan McClure1, Ushnal Rao1, Brandon Maust1, Wenjie Deng1, Justine E. Sunshine1, Moon Kim1, Morgane Rolland3,4, James I. Mullins1,2 1Department of Microbiology, University of Washington, 2Departments of Medicine and Laboratory Medicine, University of Washington, 3U.S Military HIV Research Program, Walter Reed Army Institute of Research, 4Henry M. Jackson Foundation JoVE 52610 Immunology and Infection
Pairwise Growth Competition Assay for Determining the Replication Fitness of Human Immunodeficiency Viruses Siriphan Manocheewa1, Erinn C. Lanxon-Cookson1, Yi Liu1, J. Victor Swain1, Jan McClure1, Ushnal Rao1, Brandon Maust1, Wenjie Deng1, Justine E. Sunshine1, Moon Kim1, Morgane Rolland3,4, James I. Mullins1,2 1Department of Microbiology, University of Washington, 2Departments of Medicine and Laboratory Medicine, University of Washington, 3U.S Military HIV Research Program, Walter Reed Army Institute of Research, 4Henry M. Jackson Foundation JoVE 52610 Immunology and Infection