John Roder Samuel Lunenfeld Research Institute Mount Sinai Hospital Biography Publications Institution JoVE Articles John Roder has not added a biography. If you are John Roder and would like to personalize this page please email our Author Liaison for assistance. Publications Nicotine-taking and Nicotine-seeking in C57Bl/6J Mice Without Prior Operant Training or Food Restriction Behavioural Brain Research. Feb, 2012 | Pubmed ID: 22326373 Paradoxical Roles of Serine Racemase and D-serine in the G93A MSOD1 Mouse Model of Amyotrophic Lateral Sclerosis Journal of Neurochemistry. Feb, 2012 | Pubmed ID: 22117694 Synergistic Interactions Between PDE4B and GSK-3: DISC1 Mutant Mice Neuropharmacology. Mar, 2012 | Pubmed ID: 21376063 Contributions of the D-serine Pathway to Schizophrenia Neuropharmacology. Mar, 2012 | Pubmed ID: 21295046 Acute Pharmacokinetics of Memantine in the Mouse Pharmacology. 2011 | Pubmed ID: 22068149 Mania-like Behavior Induced by Genetic Dysfunction of the Neuron-specific Na+,K+-ATPase α3 Sodium Pump Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22025725 Parametric and Pharmacological Modulations of Latent Inhibition in Mouse Inbred Strains Pharmacology, Biochemistry, and Behavior. Dec, 2011 | Pubmed ID: 21903127 Memantine Affects Cognitive Flexibility in the Morris Water Maze Journal of Alzheimer's Disease : JAD. 2011 | Pubmed ID: 21860092 Missense Mutation of the Reticulon-4 Receptor Alters Spatial Memory and Social Interaction in Mice Behavioural Brain Research. Oct, 2011 | Pubmed ID: 21645550 Genetic Inactivation of GSK3α Rescues Spine Deficits in Disc1-L100P Mutant Mice Schizophrenia Research. Jun, 2011 | Pubmed ID: 21498050 A Co-operative Regulation of Neuronal Excitability by UNC-7 Innexin and NCA/NALCN Leak Channel Molecular Brain. 2011 | Pubmed ID: 21489288 Statistical and Theoretical Considerations for the Platform Re-location Water Maze Journal of Neuroscience Methods. May, 2011 | Pubmed ID: 21419797 N-WASp is Required for Schwann Cell Cytoskeletal Dynamics, Normal Myelin Gene Expression and Peripheral Nerve Myelination Development (Cambridge, England). Apr, 2011 | Pubmed ID: 21385763 Disc1 Point Mutations in Mice Affect Development of the Cerebral Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011 | Pubmed ID: 21368031 Genetic and Pharmacological Evidence for Schizophrenia-related Disc1 Interaction with GSK-3 Synapse (New York, N.Y.). Mar, 2011 | Pubmed ID: 20687111 Short-term Memory Impairment After Isoflurane in Mice is Prevented by the α5 γ-aminobutyric Acid Type A Receptor Inverse Agonist L-655,708 Anesthesiology. Nov, 2010 | Pubmed ID: 20966663 Effects of Individual Segmental Trisomies of Human Chromosome 21 Syntenic Regions on Hippocampal Long-term Potentiation and Cognitive Behaviors in Mice Brain Research. Dec, 2010 | Pubmed ID: 20932954 A New Kv1.2 Channelopathy Underlying Cerebellar Ataxia The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20696761 Src Inhibition Reduces NR2B Surface Expression and Synaptic Plasticity in the Amygdala Learning & Memory (Cold Spring Harbor, N.Y.). Aug, 2010 | Pubmed ID: 20660101 Determination of L-serine-O-phosphate in Rat and Mouse Brain Tissue Using High-performance Liquid Chromatography and Fluorimetric Detection Analytical Biochemistry. Oct, 2010 | Pubmed ID: 20599655 Deficiencies in the Region Syntenic to Human 21q22.3 Cause Cognitive Deficits in Mice Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jun, 2010 | Pubmed ID: 20512340 A Mouse Model of Down Syndrome Trisomic for All Human Chromosome 21 Syntenic Regions Human Molecular Genetics. Jul, 2010 | Pubmed ID: 20442137 Alpha5GABAA Receptor Activity Sets the Threshold for Long-term Potentiation and Constrains Hippocampus-dependent Memory The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2010 | Pubmed ID: 20392949 A New Model of the Disrupted Latent Inhibition in C57BL/6J Mice After Bupropion Treatment Psychopharmacology. Feb, 2010 | Pubmed ID: 20013111 The Involvement of the NMDA Receptor D-serine/glycine Site in the Pathophysiology and Treatment of Schizophrenia Neuroscience and Biobehavioral Reviews. Mar, 2010 | Pubmed ID: 19695284 Abnormalities in Brain Structure and Behavior in GSK-3alpha Mutant Mice Molecular Brain. 2009 | Pubmed ID: 19925672 NCS-1 in the Dentate Gyrus Promotes Exploration, Synaptic Plasticity, and Rapid Acquisition of Spatial Memory Neuron. Sep, 2009 | Pubmed ID: 19755107 Mutation I810N in the Alpha3 Isoform of Na+,K+-ATPase Causes Impairments in the Sodium Pump and Hyperexcitability in the CNS Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19666602 Serine Racemase is Associated with Schizophrenia Susceptibility in Humans and in a Mouse Model Human Molecular Genetics. Sep, 2009 | Pubmed ID: 19483194 Beta-adrenergic Regulation of a Novel Isoform of NCX: Sequence and Expression of Shark Heart NCX in Human Kidney Cells American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2009 | Pubmed ID: 19395557 Neto1 is a Novel CUB-domain NMDA Receptor-interacting Protein Required for Synaptic Plasticity and Learning PLoS Biology. Feb, 2009 | Pubmed ID: 19243221 Genetic Inactivation of D-amino Acid Oxidase Enhances Extinction and Reversal Learning in Mice Learning & Memory (Cold Spring Harbor, N.Y.). Jan, 2009 | Pubmed ID: 19117914 Mutant Mice with Reduced NMDA-NR1 Glycine Affinity or Lack of D-amino Acid Oxidase Function Exhibit Altered Anxiety-like Behaviors Pharmacology, Biochemistry, and Behavior. Feb, 2009 | Pubmed ID: 18940194 Mice with Reduced NMDA Receptor Glycine Affinity Model Some of the Negative and Cognitive Symptoms of Schizophrenia Psychopharmacology. Oct, 2008 | Pubmed ID: 18597079 ITSN-1 Controls Vesicle Recycling at the Neuromuscular Junction and Functions in Parallel with DAB-1 Traffic (Copenhagen, Denmark). May, 2008 | Pubmed ID: 18298590 D-serine Augments NMDA-NR2B Receptor-dependent Hippocampal Long-term Depression and Spatial Reversal Learning Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2008 | Pubmed ID: 17625504 Nck Adaptor Proteins Control the Organization of Neuronal Circuits Important for Walking Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18093944 Neuronal Calcium Sensor-1 Modulation of Optimal Calcium Level for Neurite Outgrowth Development (Cambridge, England). Dec, 2007 | Pubmed ID: 18039973 Huntingtin-interacting Protein 1 Influences Worm and Mouse Presynaptic Function and Protects Caenorhabditis Elegans Neurons Against Mutant Polyglutamine Toxicity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2007 | Pubmed ID: 17928447 Disrupted in Schizophrenia 1 and Phosphodiesterase 4B: Towards an Understanding of Psychiatric Illness The Journal of Physiology. Oct, 2007 | Pubmed ID: 17823207 Behavioral Phenotypes of Disc1 Missense Mutations in Mice Neuron. May, 2007 | Pubmed ID: 17481393 Absence of the Proapoptotic Bax Protein Extends Fertility and Alleviates Age-related Health Complications in Female Mice Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360389 NMDA Receptor Function and NMDA Receptor-dependent Phosphorylation of Huntingtin is Altered by the Endocytic Protein HIP1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2007 | Pubmed ID: 17329427 The Ampakine CX546 Restores the Prepulse Inhibition and Latent Inhibition Deficits in MGluR5-deficient Mice Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2007 | Pubmed ID: 16936708 Recent Advances in Basic Neurosciences and Brain Disease: from Synapses to Behavior Molecular Pain. 2006 | Pubmed ID: 17196111 Psychosis Pathways Converge Via D2high Dopamine Receptors Synapse (New York, N.Y.). Sep, 2006 | Pubmed ID: 16786561 Methods to Rapidly and Accurately Screen a Large Number of ENU Mutagenized Mice for Abnormal Motor Phenotypes Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. Jun, 2006 | Pubmed ID: 16753976 Deletion Polymorphism of Disc1 is Common to All 129 Mouse Substrains: Implications for Gene-targeting Studies of Brain Function Genetics. Aug, 2006 | Pubmed ID: 16751659 In Vivo Magnetic Resonance Imaging and Semiautomated Image Analysis Extend the Brain Phenotype for Cdf/cdf Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2006 | Pubmed ID: 16641223 Alpha5GABAA Receptors Mediate the Amnestic but Not Sedative-hypnotic Effects of the General Anesthetic Etomidate The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2006 | Pubmed ID: 16597725 Novel Strategies for the Development of Animal Models of Refractory Epilepsy Advances in Neurology. 2006 | Pubmed ID: 16383125 Impairment in Long-term Retention but Not Short-term Performance on a Water Maze Reversal Task Following Hippocampal or Mediodorsal Striatal N-methyl-D-aspartate Receptor Blockade Behavioral Neuroscience. Dec, 2005 | Pubmed ID: 16420159 Effects of the Rd1 Mutation and Host Strain on Hippocampal Learning in Mice Behavior Genetics. Sep, 2005 | Pubmed ID: 16184487 NIH Swiss and Black Swiss Mice Have Retinal Degeneration and Performance Deficits in Cognitive Tests Comparative Medicine. Aug, 2005 | Pubmed ID: 16158906 Simplex PCR Assay for Sex Determination in Mice BioTechniques. May, 2005 | Pubmed ID: 15945368 Defective Place Cell Activity in Nociceptin Receptor Knockout Mice with Elevated NMDA Receptor-dependent Long-term Potentiation The Journal of Physiology. Jun, 2005 | Pubmed ID: 15774528 Modulators of the Glycine Site on NMDA Receptors, D-serine and ALX 5407, Display Similar Beneficial Effects to Clozapine in Mouse Models of Schizophrenia Psychopharmacology. Apr, 2005 | Pubmed ID: 15759151 Neuronal Calcium Sensor-1 Facilitates Neuronal Exocytosis Through Phosphatidylinositol 4-kinase Journal of Neurochemistry. Feb, 2005 | Pubmed ID: 15659215 The Collaborative Cross, a Community Resource for the Genetic Analysis of Complex Traits Nature Genetics. Nov, 2004 | Pubmed ID: 15514660 Calcium and Chlorpromazine Binding to the EF-hand Peptides of Neuronal Calcium Sensor-1 Peptides. Jun, 2004 | Pubmed ID: 15203236 Survey of Embryonic Stem Cell Line Source Strains in the Water Maze Reveals Superior Reversal Learning of 129S6/SvEvTac Mice Behavioural Brain Research. Jun, 2004 | Pubmed ID: 15135967 N-terminal Myristoylation Regulates Calcium-induced Conformational Changes in Neuronal Calcium Sensor-1 The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15102861 Visualization of Vesicle Transport Along and Between Distinct Pathways in Neurites of Living Cells Microscopy Research and Technique. Feb, 2004 | Pubmed ID: 14755603 Identification and Subcellular Localization of Neuronal Calcium Sensor-1 (NCS-1) in Human Neutrophils and HL-60 Cells Inflammation. Dec, 2003 | Pubmed ID: 14760944 Disruption of the Endocytic Protein HIP1 Results in Neurological Deficits and Decreased AMPA Receptor Trafficking The EMBO Journal. Jul, 2003 | Pubmed ID: 12839988 Co-stimulation of MGluR5 and N-methyl-D-aspartate Receptors is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons The Journal of Biological Chemistry. Jul, 2003 | Pubmed ID: 12740378 Spatiotemporal Distribution of Neuronal Calcium Sensor-1 in the Developing Rat Spinal Cord The Journal of Comparative Neurology. Jun, 2003 | Pubmed ID: 12717707 Aging Effects on Spatial Tuning of Hippocampal Place Cells in Mice Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale. May, 2003 | Pubmed ID: 12677315 Compartmentation of the Mouse Cerebellar Cortex by Neuronal Calcium Sensor-1 The Journal of Comparative Neurology. Apr, 2003 | Pubmed ID: 12619075 Neuronal Calcium Sensor 1 and Phosphatidylinositol 4-OH Kinase Beta Interact in Neuronal Cells and Are Translocated to Membranes During Nucleotide-evoked Exocytosis Journal of Cell Science. Oct, 2002 | Pubmed ID: 12244129 Non-ionotropic Cross-talk Between AMPA and NMDA Receptors in Rodent Hippocampal Neurones The Journal of Physiology. Aug, 2002 | Pubmed ID: 12181279 Differential Expression of Neuronal Calcium Sensor-1 in the Developing Chick Retina The Journal of Comparative Neurology. Jul, 2002 | Pubmed ID: 12115677 AMPA Receptor-mediated Miniature Synaptic Calcium Transients in GluR2 Null Mice Journal of Neurophysiology. Jul, 2002 | Pubmed ID: 12091530 Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12034721 Neuronal Calcium Sensor-1 Binds to Regulated Secretory Organelles and Functions in Basal and Stimulated Exocytosis in PC12 Cells Journal of Cell Science. Jun, 2002 | Pubmed ID: 12006624 Alterations in Exocytosis Induced by Neuronal Ca2+ Sensor-1 in Bovine Chromaffin Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2002 | Pubmed ID: 11923406 Neuronal Calcium Sensor 1 and Activity-dependent Facilitation of P/Q-type Calcium Currents at Presynaptic Nerve Terminals Science (New York, N.Y.). Mar, 2002 | Pubmed ID: 11910115 Increased Drinking in Mutant Mice with Truncated M5 Muscarinic Receptor Genes Pharmacology, Biochemistry, and Behavior. May, 2002 | Pubmed ID: 11900778 Sweeping Model of Dynamin Activity. Visualization of Coupling Between Exocytosis and Endocytosis Under an Evanescent Wave Microscope with Green Fluorescent Proteins The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11856729 Place-cell Impairment in Glutamate Receptor 2 Mutant Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2002 | Pubmed ID: 11826150 सामाजिक सहभागिता व्यवहार के मूल्यांकन Oksana Kaidanovich-Beilin1, Tatiana Lipina1, Igor Vukobradovic2, John Roder1,3,4,5, James R. Woodgett1,3 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 2Toronto Centre for Phenogenomics, Mount Sinai Hospital, 3Department of Medical Biophysics, University of Toronto, 4Department of Psychology, University of Toronto, 5Department of Psychiatry, University of Toronto JoVE 2473 Neuroscience
सामाजिक सहभागिता व्यवहार के मूल्यांकन Oksana Kaidanovich-Beilin1, Tatiana Lipina1, Igor Vukobradovic2, John Roder1,3,4,5, James R. Woodgett1,3 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 2Toronto Centre for Phenogenomics, Mount Sinai Hospital, 3Department of Medical Biophysics, University of Toronto, 4Department of Psychology, University of Toronto, 5Department of Psychiatry, University of Toronto JoVE 2473 Neuroscience