Masamitsu Iino Department of Pharmacology, Graduate School of Medicine The University of Tokyo Biography Publications Institution JoVE Articles Masamitsu Iino has not added a biography. If you are Masamitsu Iino and would like to personalize this page please email our Author Liaison for assistance. Publications Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death EBioMedicine. Aug, 2016 | Pubmed ID: 27544065 Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging Biophysical Journal. Jul, 2016 | Pubmed ID: 27477268 Whisker Experience-dependent MGluR Signaling Maintains Synaptic Strength in the Mouse Adolescent Cortex The European Journal of Neuroscience. Aug, 2016 | Pubmed ID: 27225340 Visualization of Ca2+ Filling Mechanisms Upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2015 | Pubmed ID: 26631466 Neuronal Regulation of Schwann Cell Mitochondrial Ca(2+) Signaling During Myelination Cell Reports. Sep, 2015 | Pubmed ID: 26365190 Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region PloS One. 2015 | Pubmed ID: 26115329 In Vivo Visualization of Subtle, Transient, and Local Activity of Astrocytes Using an Ultrasensitive Ca(2+) Indicator Cell Reports. Jul, 2014 | Pubmed ID: 24981861 Imaging Intraorganellar Ca2+ at Subcellular Resolution Using CEPIA Nature Communications. 2014 | Pubmed ID: 24923787 Calcium-dependent N-cadherin Up-regulation Mediates Reactive Astrogliosis and Neuroprotection After Brain Injury Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23798419 Nitric Oxide-induced Calcium Release: Activation of Type 1 Ryanodine Receptor by Endogenous Nitric Oxide Channels (Austin, Tex.). Jan, 2013 | Pubmed ID: 23247505 β-catenin Regulates Parathyroid Hormone/parathyroid Hormone-related Protein Receptor Signals and Chondrocyte Hypertrophy Through Binding to the Intracellular C-terminal Region of the Receptor Arthritis and Rheumatism. Feb, 2013 | Pubmed ID: 23124878 Nitric Oxide-induced Calcium Release Via Ryanodine Receptors Regulates Neuronal Function The EMBO Journal. Jan, 2012 | Pubmed ID: 22036948 Visualization of Glutamate As a Volume Transmitter The Journal of Physiology. Feb, 2011 | Pubmed ID: 21115644 Imaging of Ca2+ and Related Signaling Molecules and Investigation of Their Functions in the Brain Antioxidants & Redox Signaling. Apr, 2011 | Pubmed ID: 20615120 Inositol 1,4,5-trisphosphate Signaling Maintains the Activity of Glutamate Uptake in Bergmann Glia The European Journal of Neuroscience. Nov, 2010 | Pubmed ID: 20958799 Imaging Extrasynaptic Glutamate Dynamics in the Brain Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308566 Spatiotemporal Dynamics of Ca2+ Signaling and Its Physiological Roles Proceedings of the Japan Academy. Series B, Physical and Biological Sciences. 2010 | Pubmed ID: 20228624 Temporal Switching and Cell-to-cell Variability in Ca2+ Release Activity in Mammalian Cells Molecular Systems Biology. 2009 | Pubmed ID: 19293827 Functional Crosstalk Between Cell-surface and Intracellular Channels Mediated by Junctophilins Essential for Neuronal Functions Cerebellum (London, England). 2008 | Pubmed ID: 18607668 Selective Photoinactivation of Protein Function Through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer Proceedings of the National Academy of Sciences of the United States of America. Jan, 2008 | Pubmed ID: 18172220 Identification of New Functions of Ca2+ Release from Intracellular Stores in Central Nervous System Biochemical and Biophysical Research Communications. Apr, 2008 | Pubmed ID: 18053793 Regulation of Long-term Depression and Climbing Fiber Territory by Glutamate Receptor Delta2 at Parallel Fiber Synapses Through Its C-terminal Domain in Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2007 | Pubmed ID: 17978051 Involvement of Protein-tyrosine Phosphatase PTPMEG in Motor Learning and Cerebellar Long-term Depression The European Journal of Neuroscience. Oct, 2007 | Pubmed ID: 17953619 Postsynaptic GABAB Receptor Signalling Enhances LTD in Mouse Cerebellar Purkinje Cells The Journal of Physiology. Dec, 2007 | Pubmed ID: 17947316 Abnormal Features in Mutant Cerebellar Purkinje Cells Lacking Junctophilins Biochemical and Biophysical Research Communications. Nov, 2007 | Pubmed ID: 17904530 Regulation of Neurite Growth by Spontaneous Ca2+ Oscillations in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2007 | Pubmed ID: 17699677 Induction of Cerebellar Long-term Depression Requires Activation of Calcineurin in Purkinje Cells Neuropharmacology. Jun, 2007 | Pubmed ID: 17485101 Optical Glutamate Sensor for Spatiotemporal Analysis of Synaptic Transmission The European Journal of Neuroscience. Apr, 2007 | Pubmed ID: 17445223 Junctophilin-mediated Channel Crosstalk Essential for Cerebellar Synaptic Plasticity The EMBO Journal. Apr, 2007 | Pubmed ID: 17347645 Regulation of Cell Functions by Ca2+ Oscillation Advances in Experimental Medicine and Biology. 2007 | Pubmed ID: 17278375 [Trends in Physiology] Nihon Seirigaku Zasshi. Journal of the Physiological Society of Japan. 2006 | Pubmed ID: 17175877 Coupling of STIM1 to Store-operated Ca2+ Entry Through Its Constitutive and Inducible Movement in the Endoplasmic Reticulum Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17075073 Ca2+ Lightning Conveys Cell-cell Contact Information Inside the Cells EMBO Reports. Nov, 2006 | Pubmed ID: 17039254 Postsynaptic Inositol 1,4,5-trisphosphate Signaling Maintains Presynaptic Function of Parallel Fiber-Purkinje Cell Synapses Via BDNF Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16709674 Ca2+-dependent Inositol 1,4,5-trisphosphate and Nitric Oxide Signaling in Cerebellar Neurons Journal of Pharmacological Sciences. 2006 | Pubmed ID: 16682789 Ca2+ Shuttling Between Endoplasmic Reticulum and Mitochondria Underlying Ca2+ Oscillations EMBO Reports. Apr, 2006 | Pubmed ID: 16415789 Maintenance of Presynaptic Function by AMPA Receptor-mediated Excitatory Postsynaptic Activity in Adult Brain Proceedings of the National Academy of Sciences of the United States of America. Dec, 2005 | Pubmed ID: 16357208 [Analysis of Intracellular Membrane Protein Function by Small Molecule-based Chromophore-assisted Laser Inactivation] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Aug, 2005 | Pubmed ID: 16104611 NO Signalling Decodes Frequency of Neuronal Activity and Generates Synapse-specific Plasticity in Mouse Cerebellum The Journal of Physiology. Aug, 2005 | Pubmed ID: 15919714 BAD Detects Coincidence of G2/M Phase and Growth Factor Deprivation to Regulate Apoptosis The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15901741 Rapid Ca2+-dependent Increase in Oxygen Consumption by Mitochondria in Single Mammalian Central Neurons Cell Calcium. Apr, 2005 | Pubmed ID: 15755497 System-level Identification of Transcriptional Circuits Underlying Mammalian Circadian Clocks Nature Genetics. Feb, 2005 | Pubmed ID: 15665827 Real-time Imaging of Myosin II Regulatory Light-chain Phosphorylation Using a New Protein Biosensor The Biochemical Journal. Jan, 2005 | Pubmed ID: 15362955 Cross Talk Between Metabotropic and Ionotropic Glutamate Receptor-mediated Signaling in Parallel Fiber-induced Inositol 1,4,5-trisphosphate Production in Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2004 | Pubmed ID: 15509738 Modification of Intracellular Ca2+ Dynamics by Laser Inactivation of Inositol 1,4,5-trisphosphate Receptor Using Membrane-permeant Probes Chemistry & Biology. Aug, 2004 | Pubmed ID: 15324806 Molecular-timetable Methods for Detection of Body Time and Rhythm Disorders from Single-time-point Genome-wide Expression Profiles Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15273285 Universality and Flexibility in Gene Expression from Bacteria to Human Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14999098 [Ca2+ Imaging in Interstitial Cells of Cajal During Rhythmic Activity] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Mar, 2004 | Pubmed ID: 14993727 Enzymatic Production of RNAi Libraries from CDNAs Nature Genetics. Feb, 2004 | Pubmed ID: 14704669 Isoform-specific Phosphorylation of Metabotropic Glutamate Receptor 5 by Protein Kinase C (PKC) Blocks Ca2+ Oscillation and Oscillatory Translocation of Ca2+-dependent PKC The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14561742 [Not Available] Clinical Calcium. Apr, 2003 | Pubmed ID: 15775120 NFAT Functions As a Working Memory of Ca2+ Signals in Decoding Ca2+ Oscillation The EMBO Journal. Aug, 2003 | Pubmed ID: 12881417 Spatiotemporal Laser Inactivation of Inositol 1,4,5-trisphosphate Receptors Using Synthetic Small-molecule Probes Chemistry & Biology. Jun, 2003 | Pubmed ID: 12837383 Functional and Biochemical Analysis of the Type 1 Inositol (1,4,5)-trisphosphate Receptor Calcium Sensor Biophysical Journal. Jul, 2003 | Pubmed ID: 12829484 Intracellular Delivery of Glutathione S-transferase into Mammalian Cells Biochemical and Biophysical Research Communications. Jun, 2003 | Pubmed ID: 12763035 Glucose Metabolism and Glutamate Analog Acutely Alkalinize PH of Insulin Secretory Vesicles of Pancreatic Beta-cells American Journal of Physiology. Endocrinology and Metabolism. Aug, 2003 | Pubmed ID: 12644449 Effects of Insulin-like Growth Factor I on Climbing Fibre Synapse Elimination During Cerebellar Development The European Journal of Neuroscience. Feb, 2003 | Pubmed ID: 12581172 Switch to Anaerobic Glucose Metabolism with NADH Accumulation in the Beta-cell Model of Mitochondrial Diabetes. Characteristics of BetaHC9 Cells Deficient in Mitochondrial DNA Transcription The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12169697 Molecular Basis and Physiological Functions of Dynamic Ca2+ Signalling in Smooth Muscle Cells Novartis Foundation Symposium. 2002 | Pubmed ID: 12164306 Family Affairs of Intracellular Ca(2+)-release Channels The Journal of Physiology. Aug, 2002 | Pubmed ID: 12154169 A Transcription Factor Response Element for Gene Expression During Circadian Night Nature. Aug, 2002 | Pubmed ID: 12152080 Intercellular Coupling Mechanism for Synchronized and Noise-resistant Circadian Oscillators Journal of Theoretical Biology. Jun, 2002 | Pubmed ID: 12151263 The High-affinity Calcium[bond]calmodulin-binding Site Does Not Play a Role in the Modulation of Type 1 Inositol 1,4,5-trisphosphate Receptor Function by Calcium and Calmodulin The Biochemical Journal. Aug, 2002 | Pubmed ID: 11972451 Hydrophobic Modifications at 1-phosphate of Inositol 1,4,5-trisphosphate Analogues Enhance Receptor Binding Bioorganic & Medicinal Chemistry Letters. Mar, 2002 | Pubmed ID: 11958992 Novel Mutations in C-terminal Channel Region of the Ryanodine Receptor in Malignant Hyperthermia Patients Japanese Journal of Pharmacology. Feb, 2002 | Pubmed ID: 11928716 Functional Characterization of the Type 1 Inositol 1,4,5-trisphosphate Receptor Coupling Domain SII(+/-) Splice Variants and the Opisthotonos Mutant Form Biophysical Journal. Apr, 2002 | Pubmed ID: 11916857 Transient Receptor Potential 1 Regulates Capacitative Ca(2+) Entry and Ca(2+) Release from Endoplasmic Reticulum in B Lymphocytes The Journal of Experimental Medicine. Mar, 2002 | Pubmed ID: 11901194 Genome-wide Transcriptional Orchestration of Circadian Rhythms in Drosophila The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11854264 Simultaneous Imaging of Ca2+ Signals in Interstitial Cells of Cajal and Longitudinal Smooth Muscle Cells During Rhythmic Activity in Mouse Ileum The Journal of Physiology. Feb, 2002 | Pubmed ID: 11826167 Two-photon Excitation Imaging of Pancreatic Islets with Various Fluorescent Probes Diabetes. Feb, 2002 | Pubmed ID: 11815453 Phosphatidylinositol 3-kinase Suppresses Glucose-stimulated Insulin Secretion by Affecting Post-cytosolic [Ca(2+)] Elevation Signals Diabetes. Jan, 2002 | Pubmed ID: 11756327 In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation Daisuke Ino1,2, Masamitsu Iino1 1Department of Pharmacology, Graduate School of Medicine, The University of Tokyo, 2Laboratory for Cell Polarity Regulation, Quantitative Biology Center, RIKEN JoVE 54567 Neuroscience
In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation Daisuke Ino1,2, Masamitsu Iino1 1Department of Pharmacology, Graduate School of Medicine, The University of Tokyo, 2Laboratory for Cell Polarity Regulation, Quantitative Biology Center, RIKEN JoVE 54567 Neuroscience