Melanie M. Frigault

Publications

• A Phase Ib Study of the Highly Selective MET-TKI Savolitinib Plus Gefitinib in Patients with EGFR-mutated, MET-amplified Advanced Non-small-cell Lung Cancer
  Investigational New Drugs. Apr, 2021  |   Pubmed ID: 33052556
• Mechanisms of Acquired Resistance to Savolitinib, a Selective MET Inhibitor in -Amplified Gastric Cancer
  JCO Precision Oncology. 2020  |   Pubmed ID: 32923890
• A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
  Cell Reports. 07, 2020  |   Pubmed ID: 32668248
• Efficacy of Savolitinib Vs Sunitinib in Patients With MET-Driven Papillary Renal Cell Carcinoma: The SAVOIR Phase 3 Randomized Clinical Trial
  JAMA Oncology. 08, 2020  |   Pubmed ID: 32469384
• Acalabrutinib Plus Obinutuzumab in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia
  Cancer Discovery. 03, 2020  |   Pubmed ID: 31915195
• Acalabrutinib Monotherapy in Patients with Relapsed/refractory Chronic Lymphocytic Leukemia: Updated Phase 2 Results
  Blood. 04, 2020  |   Pubmed ID: 31876911
• Acalabrutinib Monotherapy in Patients with Chronic Lymphocytic Leukemia Who Are Intolerant to Ibrutinib
  Blood Advances. 05, 2019  |   Pubmed ID: 31088809
• First-in-Human Phase I Study of the Selective MET Inhibitor, Savolitinib, in Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, and Antitumor Activity
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 08, 2019  |   Pubmed ID: 30952639
• Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2017  |   Pubmed ID: 28644771
• The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2015  |   Pubmed ID: 25779944
• Is Target Validation All We Need?
  Current Opinion in Pharmacology. Aug, 2014  |   Pubmed ID: 25261632
• Are Companion Diagnostics Useful?
  Clinical Chemistry. Jan, 2013  |   Pubmed ID: 23193059