Regis Grailhe Technology Development Platform Institut Pasteur Korea Biography Publications Institution JoVE Articles Regis Grailhe has not added a biography. If you are Regis Grailhe and would like to personalize this page please email our Author Liaison for assistance. Publications Nanoluciferase Signal Brightness Using Furimazine Substrates Opens Bioluminescence Resonance Energy Transfer to Widefield Microscopy Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Aug, 2016 | Pubmed ID: 27144967 A Pathway-based Approach for Identifying Biomarkers of Tumor Progression to Trastuzumab-resistant Breast Cancer Cancer Letters. Jan, 2015 | Pubmed ID: 25449779 Dimerization, Oligomerization, and Aggregation of Human Amyotrophic Lateral Sclerosis Copper/zinc Superoxide Dismutase 1 Protein Mutant Forms in Live Cells The Journal of Biological Chemistry. May, 2014 | Pubmed ID: 24692554 Bimolecular Fluorescence Complementation; Lighting-up Tau-tau Interaction in Living Cells PloS One. 2013 | Pubmed ID: 24312574 Contactin 4, -5 and -6 Differentially Regulate Neuritogenesis While They Display Identical PTPRG Binding Sites Biology Open. Mar, 2013 | Pubmed ID: 23519440 Fluorogenic Quantum Dot-gold Nanoparticle Assembly for Beta Secretase Inhibitor Screening in Live Cell Analytical Chemistry. Oct, 2012 | Pubmed ID: 22954333 Quantification of Protein Interaction in Living Cells by Two-photon Spectral Imaging with Fluorescent Protein Fluorescence Resonance Energy Transfer Pair Devoid of Acceptor Bleed-through Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Feb, 2012 | Pubmed ID: 22076866 A Comparative Analysis of Resonance Energy Transfer Methods for Alzheimer Related Protein-protein Interactions in Living Cells Molecular BioSystems. Nov, 2011 | Pubmed ID: 21909576 Two-photon Spectral Imaging with High Temporal and Spectral Resolution Optics Express. Dec, 2010 | Pubmed ID: 21196967 Contextual Automated 3D Analysis of Subcellular Organelles Adapted to High-content Screening Journal of Biomolecular Screening. Aug, 2010 | Pubmed ID: 20639502 Compact and Versatile Nickel-nitrilotriacetate-modified Quantum Dots for Protein Imaging and Förster Resonance Energy Transfer Based Assay Langmuir : the ACS Journal of Surfaces and Colloids. May, 2010 | Pubmed ID: 20030352 PINK1-dependent Recruitment of Parkin to Mitochondria in Mitophagy Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 19966284 The Use of Cyan Fluorescent Protein Variants with a Distinctive Lifetime Signature Molecular BioSystems. Feb, 2009 | Pubmed ID: 19156260 Regional Changes in the Cholinergic System in Mice Lacking Monoamine Oxidase A Brain Research Bulletin. Mar, 2009 | Pubmed ID: 19111597 Complex Fluorescence of the Cyan Fluorescent Protein: Comparisons with the H148D Variant and Consequences for Quantitative Cell Imaging Biochemistry. Nov, 2008 | Pubmed ID: 18975974 Ni-nitrilotriacetic Acid-modified Quantum Dots As a Site-specific Labeling Agent of Histidine-tagged Proteins in Live Cells Chemical Communications (Cambridge, England). Apr, 2008 | Pubmed ID: 18401515 Nicotinic Acetylcholine Receptors Alpha4beta2 and Alpha7 Regulate Myelo- and Erythropoiesis Within the Bone Marrow The International Journal of Biochemistry & Cell Biology. 2008 | Pubmed ID: 18083057 Monitoring Protein Interactions in the Living Cell Through the Fluorescence Decays of the Cyan Fluorescent Protein Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jul, 2006 | Pubmed ID: 16739159 Mechanism of Cl- Selection by a Glutamate-gated Chloride (GluCl) Receptor Revealed Through Mutations in the Selectivity Filter The Journal of Biological Chemistry. May, 2006 | Pubmed ID: 16527818 The Role of Nicotinic Acetylcholine Receptors in Lymphocyte Development Journal of Neuroimmunology. Feb, 2006 | Pubmed ID: 16253349 Pore Conformations and Gating Mechanism of a Cys-loop Receptor Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16247006 Nicotinic Receptors Regulate B Lymphocyte Activation and Immune Response European Journal of Pharmacology. Jul, 2005 | Pubmed ID: 15963492 Perinatal Exposure to Nicotine Causes Deficits Associated with a Loss of Nicotinic Receptor Function Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15738419 14-3-3 Gamma Associates with Muscle Specific Kinase and Regulates Synaptic Gene Transcription at Vertebrate Neuromuscular Synapse Proceedings of the National Academy of Sciences of the United States of America. Dec, 2004 | Pubmed ID: 15604144 Long-term Exposure to Nicotine Modulates the Level and Activity of Acetylcholine Receptors in White Blood Cells of Smokers and Model Mice Molecular Pharmacology. Dec, 2004 | Pubmed ID: 15383622 Beta2-containing Nicotinic Receptors Contribute to the Organization of Sleep and Regulate Putative Micro-arousals in Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15215293 Nicotinic Receptors Regulate the Survival of Newborn Neurons in the Adult Olfactory Bulb Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15210938 Distinct Subcellular Targeting of Fluorescent Nicotinic Alpha 3 Beta 4 and Serotoninergic 5-HT3A Receptors in Hippocampal Neurons The European Journal of Neuroscience. Feb, 2004 | Pubmed ID: 15009132 Attenuated Response to Stress and Novelty and Hypersensitivity to Seizures in 5-HT4 Receptor Knock-out Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2004 | Pubmed ID: 14724239 Functional Role of Nicotinic Acetylcholine Receptors in Apoptosis in HL-60 Cell Line European Journal of Pharmacology. Dec, 2003 | Pubmed ID: 14660001 Functional Nicotinic Acetylcholine Receptors Are Expressed in B Lymphocyte-derived Cell Lines Molecular Pharmacology. Oct, 2003 | Pubmed ID: 14500745 Electron Microscopic Evidence for Nucleation and Growth of 3D Acetylcholine Receptor Microcrystals in Structured Lipid-detergent Matrices Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 13679581 Beta 2 Nicotinic Acetylcholine Receptor Subunit Modulates Protective Responses to Stress: A Receptor Basis for Sleep-disordered Breathing After Nicotine Exposure Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12228730 Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells Honggun Lee1, Constantin Radu1, Jeung Whan Han2, Regis Grailhe3 1Automation & Logistics Management, Screening Sciences & Novel Assay Technologies, Institut Pasteur Korea, 2School of Pharmacy, Sungkyunkwan University, 3Technology Development Platform, Institut Pasteur Korea JoVE 56425 Neuroscience
Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells Honggun Lee1, Constantin Radu1, Jeung Whan Han2, Regis Grailhe3 1Automation & Logistics Management, Screening Sciences & Novel Assay Technologies, Institut Pasteur Korea, 2School of Pharmacy, Sungkyunkwan University, 3Technology Development Platform, Institut Pasteur Korea JoVE 56425 Neuroscience