Sukumar Pal Department of Pathology and Laboratory Medicine University of California Biography Publications Institution JoVE Articles Sukumar Pal has not added a biography. If you are Sukumar Pal and would like to personalize this page please email our Author Liaison for assistance. Publications A Survey of Preclinical Studies Evaluating Nanoparticle-Based Vaccines Against Non-Viral Sexually Transmitted Infections Frontiers in Pharmacology. 2021 | Pubmed ID: 34899322 Induction of Protection in Mice Against a Respiratory Challenge by a Vaccine Formulated with the Major Outer Membrane Protein in Nanolipoprotein Particles Vaccines. Jul, 2021 | Pubmed ID: 34358171 A Primary Chlamydia Trachomatis Genital Infection of Rhesus Macaques Identifies New Immunodominant B-cell Antigens PloS One. 2021 | Pubmed ID: 33886668 Vaccines for Genital Infections: Where Are We and How Far is There to Go? Expert Review of Vaccines. 04, 2021 | Pubmed ID: 33682583 Vaccination with the Recombinant Major Outer Membrane Protein Elicits Long-term Protection in Mice Against Vaginal Shedding and Infertility Following a Genital Challenge NPJ Vaccines. 2020 | Pubmed ID: 33083025 Induction of Protection in Mice Against a Respiratory Challenge by a Vaccine Formulated with Exosomes Isolated from Infected Cells NPJ Vaccines. 2020 | Pubmed ID: 33014435 Protection Against a Chlamydial Respiratory Challenge by a Chimeric Vaccine Formulated with the Major Outer Membrane Protein Variable Domains Using the Porin B As a Scaffold NPJ Vaccines. 2020 | Pubmed ID: 32411400 Improved Protection Against Chlamydia Muridarum Using the Native Major Outer Membrane Protein Trapped in Resiquimod-carrying Amphipols and Effects in Protection with Addition of a Th1 (CpG-1826) and a Th2 (Montanide ISA 720) Adjuvant Vaccine. 06, 2020 | Pubmed ID: 32386746 Immune Response Against Chlamydia Trachomatis Via Toll-like Receptors is Negatively Regulated by SIGIRR PloS One. 2020 | Pubmed ID: 32210474 Protection of Outbred Mice Against a Vaginal Challenge by a Serovar E Recombinant Major Outer Membrane Protein Vaccine is Dependent on Phosphate Substitution in the Adjuvant Human Vaccines & Immunotherapeutics. 10, 2020 | Pubmed ID: 32118511 A Recombinant Chlamydia Trachomatis MOMP Vaccine Elicits Cross-serogroup Protection in Mice Against Vaginal Shedding and Infertility The Journal of Infectious Diseases. 01, 2020 | Pubmed ID: 31504647 Characterization of the Horizontal and Vertical Sexual Transmission of Genital Infections in a New Mouse Model Infection and Immunity. 07, 2019 | Pubmed ID: 30833332 Co-delivery of Amphipol-conjugated Adjuvant with Antigen, and Adjuvant Combinations, Enhance Immune Protection Elicited by a Membrane Protein-based Vaccine Against a Mucosal Challenge with Chlamydia Vaccine. 10, 2018 | Pubmed ID: 30293763 Transcervical Inoculation with Chlamydia Trachomatis Induces Infertility in HLA-DR4 Transgenic and Wild-Type Mice Infection and Immunity. 01, 2018 | Pubmed ID: 29038126 Comparison of the Nine Polymorphic Membrane Proteins of Chlamydia Trachomatis for Their Ability to Induce Protective Immune Responses in Mice Against a C. Muridarum Challenge Vaccine. 05, 2017 | Pubmed ID: 28385608 The Cationic Liposomal Adjuvants CAF01 and CAF09 Formulated with the Major Outer Membrane Protein Elicit Robust Protection in Mice Against a Chlamydia Muridarum Respiratory Challenge Vaccine. 03, 2017 | Pubmed ID: 28238632 Computational Modeling of TC0583 As a Putative Component of the Chlamydia Muridarum V-type ATP Synthase Complex and Assessment of Its Protective Capabilities As a Vaccine Antigen Microbes and Infection. Apr, 2016 | Pubmed ID: 26706820 A Vaccine Formulated with the Major Outer Membrane Protein Can Protect C3H/HeN, a Highly Susceptible Strain of Mice, from a Chlamydia Muridarum Genital Challenge Immunology. Nov, 2015 | Pubmed ID: 26423798 Increased Immunoaccessibility of MOMP Epitopes in a Vaccine Formulated with Amphipols May Account for the Very Robust Protection Elicited Against a Vaginal Challenge with Chlamydia Muridarum Journal of Immunology (Baltimore, Md. : 1950). Jun, 2014 | Pubmed ID: 24778450 TRAIL-R1 is a Negative Regulator of Pro-inflammatory Responses and Modulates Long-term Sequelae Resulting from Chlamydia Trachomatis Infections in Humans PloS One. 2014 | Pubmed ID: 24695582 A Vaccine Formulated with a Combination of TLR-2 and TLR-9 Adjuvants and the Recombinant Major Outer Membrane Protein Elicits a Robust Immune Response and Significant Protection Against a Chlamydia Muridarum Challenge Microbes and Infection. Mar, 2014 | Pubmed ID: 24291713 Assessment of the Role in Protection and Pathogenesis of the Chlamydia Muridarum V-type ATP Synthase Subunit A (AtpA) (TC0582) Microbes and Infection. Feb, 2014 | Pubmed ID: 24161793 Vaccination with Major Outer Membrane Protein Proteosomes Elicits Protection in Mice Against a Chlamydia Respiratory Challenge Microbes and Infection. Nov, 2013 | Pubmed ID: 23999313 Mechanism of T-cell Mediated Protection in Newborn Mice Against A Chlamydia Infection Microbes and Infection. Jul-Aug, 2013 | Pubmed ID: 23644176 Vaccination with the Recombinant Major Outer Membrane Protein Elicits Antibodies to the Constant Domains and Induces Cross-serovar Protection Against Intranasal Challenge with Chlamydia Trachomatis Infection and Immunity. May, 2013 | Pubmed ID: 23478318 Differences in Infectivity and Induction of Infertility: a Comparative Study of Chlamydia Trachomatis Strains in the Murine Model Microbes and Infection. Mar, 2013 | Pubmed ID: 23287699 마우스 모델에서 Immunodominant Chlamydial 원의 Proteomic 식별 합니다 Journal of Proteomics. Aug, 2012 | Pubmed ID: 22959960 A TLR2 Agonist is a More Effective Adjuvant for a Chlamydia Major Outer Membrane Protein Vaccine Than Ligands to Other TLR and NOD Receptors Vaccine. Sep, 2011 | Pubmed ID: 21742006 Induction of Protection Against Vaginal Shedding and Infertility by a Recombinant Chlamydia Vaccine Vaccine. Jul, 2011 | Pubmed ID: 21609745 Amphipols Stabilize the Chlamydia Major Outer Membrane Protein and Enhance Its Protective Ability As a Vaccine Vaccine. Jun, 2011 | Pubmed ID: 21550371 Immunogenicity of a Vaccine Formulated with the Chlamydia Trachomatis Serovar F, Native Major Outer Membrane Protein in a Nonhuman Primate Model Vaccine. Apr, 2011 | Pubmed ID: 21376796 Induction of Protection in Mice Against a Respiratory Challenge by a Vaccine Formulated with the Chlamydia Major Outer Membrane Protein Adjuvanted with IC31® Vaccine. Mar, 2011 | Pubmed ID: 21276442 Identification of Immunodominant Antigens by Probing a Whole Chlamydia Trachomatis Open Reading Frame Proteome Microarray Using Sera from Immunized Mice Infection and Immunity. Jan, 2011 | Pubmed ID: 20956570 A New Murine Model for Testing Vaccines Against Genital Chlamydia Trachomatis Infections in Males Vaccine. Nov, 2010 | Pubmed ID: 20920574 Enhancement of the Protective Efficacy of a Chlamydia Trachomatis Recombinant Vaccine by Combining Systemic and Mucosal Routes for Immunization Vaccine. Nov, 2010 | Pubmed ID: 20875490 Maternal Immunity Partially Protects Newborn Mice Against a Chlamydia Trachomatis Intranasal Challenge Journal of Reproductive Immunology. Nov, 2010 | Pubmed ID: 20554327 Identification of Immunodominant Antigens of Chlamydia Trachomatis Using Proteome Microarrays Vaccine. Apr, 2010 | Pubmed ID: 20044059 C3H Male Mice with Severe Combined Immunodeficiency Cannot Clear a Urethral Infection with a Human Serovar of Chlamydia Trachomatis Infection and Immunity. Dec, 2009 | Pubmed ID: 19805533 Induction of Protective Immunity by Vaccination Against Chlamydia Trachomatis Using the Major Outer Membrane Protein Adjuvanted with CpG Oligodeoxynucleotide Coupled to the Nontoxic B Subunit of Cholera Toxin Vaccine. Oct, 2009 | Pubmed ID: 19686693 클 라 미디 아의 Trachomatis 네이티브 주요 외부 막 단백질 유도 Nonhuman 영장류 부분 보호: 트 라 코 마 전송 차단 백신에 대 한 암시 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2009 | Pubmed ID: 19494332 Protection Against an Intranasal Challenge by Vaccines Formulated with Native and Recombinant Preparations of the Chlamydia Trachomatis Major Outer Membrane Protein Vaccine. Aug, 2009 | Pubmed ID: 19446590 지연 형 과민 반응과 Kv1.3 채널 블록으로 억제 하는 동안 이펙터 메모리 T 세포의 영상 Immunity. Oct, 2008 | Pubmed ID: 18835197 Protection of Wild-type and Severe Combined Immunodeficiency Mice Against an Intranasal Challenge by Passive Immunization with Monoclonal Antibodies to the Chlamydia Trachomatis Mouse Pneumonitis Major Outer Membrane Protein Infection and Immunity. Dec, 2008 | Pubmed ID: 18809664 Structural and Functional Analyses of the Major Outer Membrane Protein of Chlamydia Trachomatis Journal of Bacteriology. Sep, 2007 | Pubmed ID: 17601785 Role of Matrix Metalloproteinase-7 in the Modulation of a Chlamydia Trachomatis Infection Immunology. Feb, 2006 | Pubmed ID: 16423057 Immunization with the Chlamydia Trachomatis Major Outer Membrane Protein, Using Adjuvants Developed for Human Vaccines, Can Induce Partial Protection in a Mouse Model Against a Genital Challenge Vaccine. Feb, 2006 | Pubmed ID: 16199110 Vaccination with the Chlamydia Trachomatis Major Outer Membrane Protein Can Elicit an Immune Response As Protective As That Resulting from Inoculation with Live Bacteria Infection and Immunity. Dec, 2005 | Pubmed ID: 16299310 Vaccination of Newborn Mice Induces a Strong Protective Immune Response Against Respiratory and Genital Challenges with Chlamydia Trachomatis Vaccine. Nov, 2005 | Pubmed ID: 16085340 New Murine Model for the Study of Chlamydia Trachomatis Genitourinary Tract Infections in Males Infection and Immunity. Jul, 2004 | Pubmed ID: 15213165 Induction of Protective Immunity Against a Chlamydia Trachomatis Genital Infection in Three Genetically Distinct Strains of Mice Immunology. Nov, 2003 | Pubmed ID: 14632665 Immunization with the Chlamydia Trachomatis Major Outer Membrane Protein, Using the Outer Surface Protein A of Borrelia Burgdorferi As an Adjuvant, Can Induce Protection Against a Chlamydial Genital Challenge Vaccine. Mar, 2003 | Pubmed ID: 12615442 Immunization with the Chlamydia Trachomatis Mouse Pneumonitis Major Outer Membrane Protein by Use of CpG Oligodeoxynucleotides As an Adjuvant Induces a Protective Immune Response Against an Intranasal Chlamydial Challenge Infection and Immunity. Sep, 2002 | Pubmed ID: 12183524 Immunization with the Chlamydia Trachomatis Mouse Pneumonitis Major Outer Membrane Protein Can Elicit a Protective Immune Response Against a Genital Challenge Infection and Immunity. Oct, 2001 | Pubmed ID: 11553566 Susceptibility of Mice to Vaginal Infection with Chlamydia Trachomatis Mouse Pneumonitis is Dependent on the Age of the Animal Infection and Immunity. Aug, 2001 | Pubmed ID: 11447208 Role of Nramp1 Deletion in Chlamydia Infection in Mice Infection and Immunity. Aug, 2000 | Pubmed ID: 10899900 Immunogenic and Protective Ability of the Two Developmental Forms of Chlamydiae in a Mouse Model of Infertility Vaccine. Nov, 1999 | Pubmed ID: 10547436 A Murine Model for the Study of Chlamydia Trachomatis Genital Infections During Pregnancy Infection and Immunity. May, 1999 | Pubmed ID: 10225927 백신 개발을 위한 Chlamydia muridarum 의 재조합 주요 외막 단백질에 무세포 규모 생산 및 보조제 추가 Sean F. Gilmore*1, Wei He*1, Angela C. Evans1, Delia F. Tifrea2, Sukumar Pal2, Brent Segelke1, Sandra K. G. Peters1, B. Dillon Vannest1, Nicholas O. Fischer1, Amy Rasley1, Luis M. de la Maza2, Matthew A. Coleman1,3 1Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, 2Department of Pathology and Laboratory Medicine, University of California, 3School of Medicine, Radiation Oncology, University of California Davis JoVE 63028 Immunology and Infection
백신 개발을 위한 Chlamydia muridarum 의 재조합 주요 외막 단백질에 무세포 규모 생산 및 보조제 추가 Sean F. Gilmore*1, Wei He*1, Angela C. Evans1, Delia F. Tifrea2, Sukumar Pal2, Brent Segelke1, Sandra K. G. Peters1, B. Dillon Vannest1, Nicholas O. Fischer1, Amy Rasley1, Luis M. de la Maza2, Matthew A. Coleman1,3 1Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, 2Department of Pathology and Laboratory Medicine, University of California, 3School of Medicine, Radiation Oncology, University of California Davis JoVE 63028 Immunology and Infection