Sung-Joon Lee Department of Biotechnology, Graduate School of Life Sciences & Biotechnology, College of Life Sciences and Biotechnology Korea University Biography Publications Institution JoVE Articles Sung-Joon Lee has not added a biography. If you are Sung-Joon Lee and would like to personalize this page please email our Author Liaison for assistance. Publications Olfactory Receptor 43 Reduces Hepatic Lipid Accumulation and Adiposity in Mice Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. Apr, 2019 | Pubmed ID: 30639733 Therapeutic Potential of Ectopic Olfactory and Taste Receptors Nature Reviews. Drug Discovery. Feb, 2019 | Pubmed ID: 30504792 Antiviral Activity of Schizonepeta Tenuifolia Briquet Against Noroviruses Via Induction of Antiviral Interferons Journal of Microbiology (Seoul, Korea). Sep, 2018 | Pubmed ID: 30141161 Chicoric Acid Mitigates Impaired Insulin Sensitivity by Improving Mitochondrial Function Bioscience, Biotechnology, and Biochemistry. Jul, 2018 | Pubmed ID: 29557265 Effects of L-arginine on Growth Hormone and Insulin-like Growth Factor 1 Food Science and Biotechnology. 2017 | Pubmed ID: 30263714 Betaine Reduces Cellular Melanin Content Via Suppression of Microphthalmia-associated Transcription Factor in B16-F1 Murine Melanocytes Food Science and Biotechnology. 2017 | Pubmed ID: 30263674 Olfactory Receptor 544 Reduces Adiposity by Steering Fuel Preference Toward Fats The Journal of Clinical Investigation. Nov, 2017 | Pubmed ID: 28990936 Barley Sprout Extracts Reduce Hepatic Lipid Accumulation in Ethanol-fed Mice by Activating Hepatic AMP-activated Protein Kinase Food Research International (Ottawa, Ont.). Nov, 2017 | Pubmed ID: 28941686 Inactivation of Norovirus by Lemongrass Essential Oil Using a Norovirus Surrogate System Journal of Food Protection. 08, 2017 | Pubmed ID: 28699786 Classification of Hydrocolloids Based on in Vitro Starch Digestibility and Rheological Properties of Segoami Gel International Journal of Biological Macromolecules. Nov, 2017 | Pubmed ID: 28627390 Protocatechuic Acid Enhances Osteogenesis, but Inhibits Adipogenesis in C3H10T1/2 and 3T3-L1 Cells Journal of Medicinal Food. Mar, 2017 | Pubmed ID: 28296593 Molecular Determinants of the Olfactory Receptor Olfr544 Activation by Azelaic Acid Biochemical and Biophysical Research Communications. 04, 2017 | Pubmed ID: 28235481 Fermented Green Tea Extract Exhibits Hypolipidaemic Effects Through the Inhibition of Pancreatic Lipase and Promotion of Energy Expenditure The British Journal of Nutrition. 01, 2017 | Pubmed ID: 28132656 Quercetin Intake, MATE1 Polymorphism, and Metabolic Syndrome in Korean Population: Hallym Aging Study Food Science and Biotechnology. 2016 | Pubmed ID: 30263475 Brown Rice ( L. Cv. Hiami) Extract Promotes Cellular Growth by Upregulation of GH and IGF-1 Expression and Secretion Food Science and Biotechnology. 2016 | Pubmed ID: 30263275 Curcumin Shows Antiviral Properties Against Norovirus Molecules (Basel, Switzerland). Oct, 2016 | Pubmed ID: 27775614 Syringaresinol Induces Mitochondrial Biogenesis Through Activation of PPARβ Pathway in Skeletal Muscle Cells Bioorganic & Medicinal Chemistry Letters. 08, 2016 | Pubmed ID: 27450788 Astaxanthin Reduces Hepatic Lipid Accumulations in High-fat-fed C57BL/6J Mice Via Activation of Peroxisome Proliferator-activated Receptor (PPAR) Alpha and Inhibition of PPAR Gamma and Akt The Journal of Nutritional Biochemistry. Feb, 2016 | Pubmed ID: 26878778 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Notch1 Deficiency Decreases Hepatic Lipid Accumulation by Induction of Fatty Acid Oxidation Scientific Reports. Jan, 2016 | Pubmed ID: 26786165 Saponarin Activates AMPK in a Calcium-dependent Manner and Suppresses Gluconeogenesis and Increases Glucose Uptake Via Phosphorylation of CRTC2 and HDAC5 Bioorganic & Medicinal Chemistry Letters. Nov, 2015 | Pubmed ID: 26471090 Kaempferol Ameliorates Symptoms of Metabolic Syndrome by Regulating Activities of Liver X Receptor-β The Journal of Nutritional Biochemistry. Aug, 2015 | Pubmed ID: 25959373 Gene Expression Profiles of Primary Retinal Pigment Epithelial Cells from Apolipoprotein E Knockout and Human Apolipoprotein E2 Transgenic Mice Genetics and Molecular Research : GMR. Mar, 2015 | Pubmed ID: 25867331 Activation of OR1A1 Suppresses PPAR-γ Expression by Inducing HES-1 in Cultured Hepatocytes The International Journal of Biochemistry & Cell Biology. Jul, 2015 | Pubmed ID: 25817041 Fermented Green Tea Extract Alleviates Obesity and Related Complications and Alters Gut Microbiota Composition in Diet-induced Obese Mice Journal of Medicinal Food. May, 2015 | Pubmed ID: 25764354 The Effect of Bioactive Compounds in Tea on Lipid Metabolism and Obesity Through Regulation of Peroxisome Proliferator-activated Receptors Current Opinion in Lipidology. Feb, 2015 | Pubmed ID: 25551797 Ursolic Acid Improves Lipid and Glucose Metabolism in High-fat-fed C57BL/6J Mice by Activating Peroxisome Proliferator-activated Receptor Alpha and Hepatic Autophagy Molecular Nutrition & Food Research. Feb, 2015 | Pubmed ID: 25418615 Inactivation of Norovirus and Surrogates by Natural Phytochemicals and Bioactive Substances Molecular Nutrition & Food Research. Jan, 2015 | Pubmed ID: 25410634 The Dipeptide H-Trp-Arg-OH (WR) Is a PPARα Agonist and Reduces Hepatic Lipid Accumulation in Lipid-loaded H4IIE Cells Applied Biochemistry and Biotechnology. Jan, 2015 | Pubmed ID: 25377249 Multidrug and Toxic Compound Extrusion Protein-1 (MATE1/SLC47A1) is a Novel Flavonoid Transporter Journal of Agricultural and Food Chemistry. Oct, 2014 | Pubmed ID: 25241911 Trans-Caryophyllene is a Natural Agonistic Ligand for Peroxisome Proliferator-activated Receptor-α Bioorganic & Medicinal Chemistry Letters. Jul, 2014 | Pubmed ID: 24856059 The Dipeptide H-Trp-Glu-OH (WE) Shows Agonistic Activity to Peroxisome Proliferator-activated Protein-α and Reduces Hepatic Lipid Accumulation in Lipid-loaded H4IIE Cells Bioorganic & Medicinal Chemistry Letters. Jul, 2014 | Pubmed ID: 24821375 Hempseed Oil Induces Reactive Oxygen Species- and C/EBP Homologous Protein-mediated Apoptosis in MH7A Human Rheumatoid Arthritis Fibroblast-like Synovial Cells Journal of Ethnopharmacology. Jul, 2014 | Pubmed ID: 24814038 Linalool is a PPARα Ligand That Reduces Plasma TG Levels and Rewires the Hepatic Transcriptome and Plasma Metabolome Journal of Lipid Research. 06, 2014 | Pubmed ID: 24752549 Coumestrol Induces Mitochondrial Biogenesis by Activating Sirt1 in Cultured Skeletal Muscle Cells Journal of Agricultural and Food Chemistry. May, 2014 | Pubmed ID: 24712520 Hypolipidemic and Antiinflammation Activities of Fermented Soybean Fibers from Meju in C57BL/6 J Mice Phytotherapy Research : PTR. Sep, 2014 | Pubmed ID: 24623672 [Efficacy of Fenoverine and Trimebutine in the Management of Irritable Bowel Syndrome: Multicenter Randomized Double-blind Non-inferiority Clinical Study] The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi. Nov, 2013 | Pubmed ID: 24262593 Cyanidin, a Natural Flavonoid, is an Agonistic Ligand for Liver X Receptor Alpha and Beta and Reduces Cellular Lipid Accumulation in Macrophages and Hepatocytes Bioorganic & Medicinal Chemistry Letters. Jul, 2013 | Pubmed ID: 23769638 Ombuin-3-O-β-D-glucopyranoside from Gynostemma Pentaphyllum is a Dual Agonistic Ligand of Peroxisome Proliferator-activated Receptors α and δ/β Biochemical and Biophysical Research Communications. Jan, 2013 | Pubmed ID: 23247028 Induction of ABCA1 and ABCG1 Expression by the Liver X Receptor Modulator Cineole in Macrophages Bioorganic & Medicinal Chemistry Letters. Jan, 2013 | Pubmed ID: 23246324 Cyanidin is an Agonistic Ligand for Peroxisome Proliferator-activated Receptor-alpha Reducing Hepatic Lipid Biochimica Et Biophysica Acta. Apr, 2013 | Pubmed ID: 23228689 Fucosterol is a Selective Liver X Receptor Modulator That Regulates the Expression of Key Genes in Cholesterol Homeostasis in Macrophages, Hepatocytes, and Intestinal Cells Journal of Agricultural and Food Chemistry. Nov, 2012 | Pubmed ID: 23116181 Dual Inhibition of γ-oryzanol on Cellular Melanogenesis: Inhibition of Tyrosinase Activity and Reduction of Melanogenic Gene Expression by a Protein Kinase A-dependent Mechanism Journal of Natural Products. Oct, 2012 | Pubmed ID: 23031087 Iristectorigenin B Isolated from Belamcanda Chinensis is a Liver X Receptor Modulator That Increases ABCA1 and ABCG1 Expression in Macrophage RAW 264.7 Cells Biotechnology Letters. Dec, 2012 | Pubmed ID: 23011313 Hepatic Lipid Accumulation Alters Global Histone H3 Lysine 9 and 4 Trimethylation in the Peroxisome Proliferator-activated Receptor Alpha Network PloS One. 2012 | Pubmed ID: 22973438 Taurine is a Liver X Receptor-α Ligand and Activates Transcription of Key Genes in the Reverse Cholesterol Transport Without Inducing Hepatic Lipogenesis Molecular Nutrition & Food Research. Jun, 2012 | Pubmed ID: 22707265 The Natural Carotenoid Astaxanthin, a PPAR-α Agonist and PPAR-γ Antagonist, Reduces Hepatic Lipid Accumulation by Rewiring the Transcriptome in Lipid-loaded Hepatocytes Molecular Nutrition & Food Research. Jun, 2012 | Pubmed ID: 22707263 Catalposide is a Natural Agonistic Ligand of Peroxisome Proliferator-activated Receptor-α Biochemical and Biophysical Research Communications. Jun, 2012 | Pubmed ID: 22583896 Ethyl 2,4,6-trihydroxybenzoate is an Agonistic Ligand for Liver X Receptor That Induces Cholesterol Efflux from Macrophages Without Affecting Lipid Accumulation in HepG2 Cells Bioorganic & Medicinal Chemistry Letters. Jun, 2012 | Pubmed ID: 22579484 Polyhydroxylated Macrolides from Seimatosporium Discosioides and Their Effects on the Activation of Peroxisome Proliferator-activated Receptor Gamma Journal of Natural Products. Apr, 2012 | Pubmed ID: 22424300 Acute Effect of High-dose Isoflavones from Pueraria Lobata (Willd.) Ohwi on Lipid and Bone Metabolism in Ovariectomized Mice Phytotherapy Research : PTR. Dec, 2012 | Pubmed ID: 22422661 Acetylenic Acid Analogues from the Edible Mushroom Chanterelle (Cantharellus Cibarius) and Their Effects on the Gene Expression of Peroxisome Proliferator-activated Receptor-gamma Target Genes Bioorganic & Medicinal Chemistry Letters. Mar, 2012 | Pubmed ID: 22342624 Melissa Officinalis Essential Oil Reduces Plasma Triglycerides in Human Apolipoprotein E2 Transgenic Mice by Inhibiting Sterol Regulatory Element-binding Protein-1c-dependent Fatty Acid Synthesis The Journal of Nutrition. Mar, 2012 | Pubmed ID: 22279139 Ethanol-induced DNA Damage and Repair-related Molecules in Human Intestinal Epithelial Caco-2 Cells Molecular Medicine Reports. Apr, 2012 | Pubmed ID: 22246134 Momilactione B Inhibits Protein Kinase A Signaling and Reduces Tyrosinase-related Proteins 1 and 2 Expression in Melanocytes Biotechnology Letters. May, 2012 | Pubmed ID: 22215377 Evidence for Protein-mediated Fatty Acid Efflux by Adipocytes Acta Physiologica (Oxford, England). Apr, 2012 | Pubmed ID: 21951599 Nanoemulsified Green Tea Extract Shows Improved Hypocholesterolemic Effects in C57BL/6 Mice The Journal of Nutritional Biochemistry. Feb, 2012 | Pubmed ID: 21447439 Linalool Reduces the Expression of 3-hydroxy-3-methylglutaryl CoA Reductase Via Sterol Regulatory Element Binding Protein-2- and Ubiquitin-dependent Mechanisms FEBS Letters. Oct, 2011 | Pubmed ID: 21944868 Antiulcer Activity of Anthocyanins from Rubus Coreanus Via Association with Regulation of the Activity of Matrix Metalloproteinase-2 Journal of Agricultural and Food Chemistry. Nov, 2011 | Pubmed ID: 21942741 Critical Role of Peroxisome Proliferator Activated Receptor-δ on Body Fat Reduction in C57BL/6J and Human Apolipoprotein E2 Transgenic Mice Fed Delipidated Soybean Journal of Agricultural and Food Chemistry. Nov, 2011 | Pubmed ID: 21894990 Ursolic Acid is a PPAR-α Agonist That Regulates Hepatic Lipid Metabolism Bioorganic & Medicinal Chemistry Letters. Oct, 2011 | Pubmed ID: 21855333 Is Intercellular Space Different Among Layers in Normal Esophageal Mucosa? An Electron Microscopic Study Digestive Diseases and Sciences. Dec, 2011 | Pubmed ID: 21735082 Barley Intake Induces Bile Acid Excretion by Reduced Expression of Intestinal ASBT and NPC1L1 in C57BL/6J Mice Journal of Agricultural and Food Chemistry. Jun, 2011 | Pubmed ID: 21591702 Hypocholesterolemic and Hypoglycemic Effects of Enzymatically Modified Carbohydrates from Rice in High-fat-fed C57BL/6J Mice Molecular Nutrition & Food Research. Sep, 2011 | Pubmed ID: 21538857 Effects of Acute Oral Administration of Vitamin C on the Mouse Liver Transcriptome Journal of Medicinal Food. Mar, 2011 | Pubmed ID: 21332396 Electron Microscopic Study of Intercellular Space: Correlation Analysis of Bronchial Asthma and Gastroesophageal Reflux Disease Journal of Gastroenterology and Hepatology. Jan, 2011 | Pubmed ID: 21175802 Limonene, a Natural Cyclic Terpene, is an Agonistic Ligand for Adenosine A(2A) Receptors Biochemical and Biophysical Research Communications. Jan, 2011 | Pubmed ID: 21134357 Toxicological Evaluation of Fucoidan from Undaria Pinnatifidain Vitro and in Vivo Phytotherapy Research : PTR. Jul, 2010 | Pubmed ID: 20578121 An Electron Microscopic Study--correlation of Gastroesophageal Reflux Disease and Laryngopharyngeal Reflux The Laryngoscope. Jul, 2010 | Pubmed ID: 20564655 Hypocholesterolemic Effects of Lactobacillus Plantarum KCTC3928 by Increased Bile Acid Excretion in C57BL/6 Mice Nutrition (Burbank, Los Angeles County, Calif.). Mar, 2010 | Pubmed ID: 19695834 Correlation of Urinary Furan with Plasma Gamma-glutamyltranspeptidase Levels in Healthy Men and Women Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. May, 2008 | Pubmed ID: 18295953 Antioxidative and Hypocholesterolemic Activities of Water-soluble Puerarin Glycosides in HepG2 Cells and in C57 BL/6J Mice European Journal of Pharmacology. Jan, 2008 | Pubmed ID: 17976573 Asian Plantain (Plantago Asiatica) Essential Oils Suppress 3-hydroxy-3-methyl-glutaryl-co-enzyme A Reductase Expression in Vitro and in Vivo and Show Hypocholesterolaemic Properties in Mice The British Journal of Nutrition. Jan, 2008 | Pubmed ID: 17697428 Human Apolipoprotein E2 Transgenic Mice Show Lipid Accumulation in Retinal Pigment Epithelium and Altered Expression of VEGF and BFGF in the Eyes Journal of Microbiology and Biotechnology. Jun, 2007 | Pubmed ID: 18050922 A 90 Day Repeated Oral Toxicity Study on Plantamajoside Concentrate from Plantago Asiatica Phytotherapy Research : PTR. Dec, 2007 | Pubmed ID: 17622978 The Effect of Essential Oils of Dietary Wormwood (Artemisia Princeps), with and Without Added Vitamin E, on Oxidative Stress and Some Genes Involved in Cholesterol Metabolism Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Aug, 2007 | Pubmed ID: 17368686 Non-radioactive and Colorimetric Quantification of Monocyte Adhesion to Endothelial Cells in Early Atherogenesis Biotechnology Letters. Nov, 2006 | Pubmed ID: 17028917 Cytotoxicity of Nitric Oxide is Alleviated by Zinc-mediated Expression of Antioxidant Genes Experimental Biology and Medicine (Maywood, N.J.). Oct, 2006 | Pubmed ID: 17018880 Water-soluble Genistin Glycoside Isoflavones Up-regulate Antioxidant Metallothionein Expression and Scavenge Free Radicals Journal of Agricultural and Food Chemistry. May, 2006 | Pubmed ID: 16719502 Removal of Chylomicron Remnants in Transgenic Mice Overexpressing Normal and Membrane-anchored Hepatic Lipase Journal of Lipid Research. Jan, 2005 | Pubmed ID: 15520453 Quantificação de hipopigmentação atividade In Vitro Yeon-Ji Kim1, Min-Jung Kim1, Dong-Keon Kweon2, Seung-Taik Lim1, Sung-Joon Lee1 1Department of Biotechnology, Graduate School of Life Sciences & Biotechnology, College of Life Sciences and Biotechnology, Korea University, 2JinWoo Bio Co. Ltd JoVE 58185 Biochemistry
Quantificação de hipopigmentação atividade In Vitro Yeon-Ji Kim1, Min-Jung Kim1, Dong-Keon Kweon2, Seung-Taik Lim1, Sung-Joon Lee1 1Department of Biotechnology, Graduate School of Life Sciences & Biotechnology, College of Life Sciences and Biotechnology, Korea University, 2JinWoo Bio Co. Ltd JoVE 58185 Biochemistry