Analyzing Alveolar Bone Remodeling to Explore Skeletal Mechanical Biology

July 21, 2023

유도 가능한 조골 계통 특이적 Stat3 녹아웃 마우스를 사용하여 교정 치아 운동 중 치조골 리모델링 연구

Murine Orthodontic Tooth Movement(OTM) 모델

Murine Alveolar Bone Specimen Collection

Yuanqi Liu*^1,2,3,4,5, Siyuan Sun*^1,2,3,4,5, Ziyi Jiang*⁶, Xinyi Gong^2,3,4,5, Yiling Yang^2,3,4,5, Yanfei Zhu^2,3,4,5, Hongyuan Xu^2,3,4,5, Anting Jin^2,3,4,5, Xiangru Huang^2,3,4,5, Xin Gao^2,3,4,5, Tingwei Lu^2,3,4,5, Jingyi Liu^2,3,4,5, Xinyu Wang^2,3,4,5, Qinggang Dai^3,4,5,7, Lingyong Jiang^2,3,4,5

¹Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Surgery, Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine, ²College of Stomatology,Shanghai Jiao Tong University, ³National Center for Stomatology, ⁴National Clinical Research Center for Oral Diseases, ⁵Shanghai Key Laboratory of Stomatology, ⁶Shanghai Starriver Bilingual School, ⁷The 2nd Dental Center, Ninth People’s Hospital, Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine

Summary

본 연구는 유도성 조골세포 계통 특이적 Stat3 녹아웃 마우스를 사용하여 교정력 하에서 뼈 리모델링을 연구하기 위한 프로토콜을 제공하고, 치아 교정 운동 중 치조골 리모델링을 분석하는 방법을 설명하여 골격 기계 생물학에 대한 실마리를 제공합니다.

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