Sophie Regan MRC Centre for Drug Safety Science and Institute of Translational Medicine University of Liverpool Biography Publications Institution JoVE Articles Sophie Regan has not added a biography. If you are Sophie Regan and would like to personalize this page please email our Author Liaison for assistance. Publications Timescale Analysis of a Mathematical Model of Acetaminophen Metabolism and Toxicity Journal of Theoretical Biology. Dec, 2015 | Pubmed ID: 26348886 Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients The Journal of Pharmacology and Experimental Therapeutics. Aug, 2014 | Pubmed ID: 24902585 The Impact of Early Postoperative Pain on Health-related Quality of Life Pain Practice : the Official Journal of World Institute of Pain. Sep, 2013 | Pubmed ID: 23279591 The Generation, Detection, and Effects of Reactive Drug Metabolites Medicinal Research Reviews. Sep, 2013 | Pubmed ID: 23090860 Haloarene Derivatives of Carbamazepine with Reduced Bioactivation Liabilities: 2-monohalo and 2,8-dihalo Derivatives Journal of Medicinal Chemistry. Nov, 2012 | Pubmed ID: 23088585 The Genotoxic Potential of Methapyrilene Using the Alkaline Comet Assay in Vitro and in Vivo Toxicology. Dec, 2011 | Pubmed ID: 22015589 Convenient Syntheses of Benzo-fluorinated Dibenz[b,f]azepines: Rearrangements of Isatins, Acridines, and Indoles Organic Letters. Oct, 2011 | Pubmed ID: 21939196 Acyl Glucuronides: the Good, the Bad and the Ugly Biopharmaceutics & Drug Disposition. Oct, 2010 | Pubmed ID: 20830700 High-mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-induced Necrosis and Apoptosis in Vivo Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2009 | Pubmed ID: 19783637 Functional and Toxicological Consequences of Metabolic Bioactivation of Methapyrilene Via Thiophene S-oxidation: Induction of Cell Defence, Apoptosis and Hepatic Necrosis Toxicology and Applied Pharmacology. Sep, 2009 | Pubmed ID: 19523481 Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture Michael P. Storm1, Ian Sorrell2, Rebecca Shipley3, Sophie Regan2, Kim A. Luetchford1, Jean Sathish2, Steven Webb4, Marianne J. Ellis1 1Department of Chemical Engineering and Centre for Regenerative Medicine, University of Bath, 2MRC Centre for Drug Safety Science and Institute of Translational Medicine, University of Liverpool, 3Mechanical Engineering, University College London, 4Department of Applied Mathematics, Liverpool John Moores University JoVE 53431 Biotechnik
Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture Michael P. Storm1, Ian Sorrell2, Rebecca Shipley3, Sophie Regan2, Kim A. Luetchford1, Jean Sathish2, Steven Webb4, Marianne J. Ellis1 1Department of Chemical Engineering and Centre for Regenerative Medicine, University of Bath, 2MRC Centre for Drug Safety Science and Institute of Translational Medicine, University of Liverpool, 3Mechanical Engineering, University College London, 4Department of Applied Mathematics, Liverpool John Moores University JoVE 53431 Biotechnik