Addmore Shonhai Department of Biochemistry & Microbiology University of Venda Biography Publications Institution JoVE Articles Addmore Shonhai has not added a biography. If you are Addmore Shonhai and would like to personalize this page please email our Author Liaison for assistance. Publications Correction: Bopape Et Al. The Genome of a Pigeonpea Compatible Rhizobial Strain '10ap3' Appears to Lack Common Nodulation Genes. 2023, , 1084 Genes. Jan, 2024 | Pubmed ID: 38255010 Ursolic Acid Acetate and Iso-mukaadial Acetate Bind to Plasmodium Falciparum Hsp90, Abrogating Its Chaperone Function in Vitro Naunyn-Schmiedeberg's Archives of Pharmacology. Jan, 2024 | Pubmed ID: 38252299 Insertion of GGMP Repeat Residues of Plasmodium Falciparum Hsp70-1 in the Lid of DnaK Adversely Impacts Client Recognition International Journal of Biological Macromolecules. Jan, 2024 | Pubmed ID: 37981279 The Multi-faceted Roles of R2TP Complex Span Across Regulation of Gene Expression, Translation, and Protein Functional Assembly Biophysical Reviews. Dec, 2023 | Pubmed ID: 38192347 Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting Hsp90 ACS Omega. Oct, 2023 | Pubmed ID: 37867657 2-Hydroxypropyl-β-cyclodextrin (HPβCD) As a Potential Therapeutic Agent for Breast Cancer Cancers. May, 2023 | Pubmed ID: 37345165 The Genome of a Pigeonpea Compatible Rhizobial Strain '10ap3' Appears to Lack Common Nodulation Genes Genes. May, 2023 | Pubmed ID: 37239443 Human Granzyme B Binds Plasmodium Falciparum Hsp70-x and Mediates Antiplasmodial Activity in Vitro Cell Stress & Chaperones. May, 2023 | Pubmed ID: 37074531 Inhibition of Hsp70-Hop Partnership by 2-phenylthynesulfonamide Frontiers in Molecular Biosciences. 2022 | Pubmed ID: 36177352 Host Cell Stress Response As a Predictor of COVID-19 Infectivity and Disease Progression Frontiers in Molecular Biosciences. 2022 | Pubmed ID: 36032680 Heat Shock Proteins of Malaria: Highlights and Future Prospects Advances in Experimental Medicine and Biology. 2021 | Pubmed ID: 34569028 Bioprospecting for Novel Heat Shock Protein Modulators: The New Frontier for Antimalarial Drug Discovery? Advances in Experimental Medicine and Biology. 2021 | Pubmed ID: 34569026 The Role of Hsp70s in the Development and Pathogenicity of Plasmodium Falciparum Advances in Experimental Medicine and Biology. 2021 | Pubmed ID: 34569021 Heat Shock Proteins: Potential Modulators and Candidate Biomarkers of Peripartum Cardiomyopathy Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34222357 Characterization of an Atypical Hsp70 Demonstrates Its Cytosolic-Nuclear Localization and Modulation by Quercetin and Methylene Blue International Journal of Molecular Sciences. Jun, 2021 | Pubmed ID: 34202520 Supporting Data on Characterisation of Linker Switch Mutants of Heat Shock Protein 110 and Canonical Hsp70 Data in Brief. Aug, 2021 | Pubmed ID: 34141839 'Meet the Editor Series'-Addmore Shonhai Biophysical Reviews. Apr, 2021 | Pubmed ID: 33927784 Design and Synthesis of Quinoline-pyrimidine Inspired Hybrids As Potential Plasmodial Inhibitors European Journal of Medicinal Chemistry. May, 2021 | Pubmed ID: 33744688 Characterisation of a Unique Linker Segment of the Plasmodium Falciparum Cytosol Localised Hsp110 Chaperone International Journal of Biological Macromolecules. Jun, 2021 | Pubmed ID: 33741370 Mutation of GGMP Repeat Segments of Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding International Journal of Molecular Sciences. Feb, 2021 | Pubmed ID: 33672387 The Role of Non-Canonical Hsp70s (Hsp110/Grp170) in Cancer Cells. Jan, 2021 | Pubmed ID: 33525518 Comparative Characterization of Hsp70-1 Relative to DnaK Reveals the Functional Specificity of the Parasite Chaperone Biomolecules. Jun, 2020 | Pubmed ID: 32512819 Biophysical Analysis of Plasmodium Falciparum Hsp70-Hsp90 Organising Protein (PfHop) Reveals a Monomer That is Characterised by Folded Segments Connected by Flexible Linkers PloS One. 2020 | Pubmed ID: 32343703 Small Molecule Inhibitors Targeting the Heat Shock Protein System of Human Obligate Protozoan Parasites International Journal of Molecular Sciences. Nov, 2019 | Pubmed ID: 31775392 Plasmodium Falciparum R2TP Complex: Driver of Parasite Hsp90 Function Biophysical Reviews. Dec, 2019 | Pubmed ID: 31734827 The Link That Binds: The Linker of Hsp70 As a Helm of the Protein's Function Biomolecules. Sep, 2019 | Pubmed ID: 31569820 Partners in Mischief: Functional Networks of Heat Shock Proteins of and Their Influence on Parasite Virulence Biomolecules. Jul, 2019 | Pubmed ID: 31340488 Comparative Structure-function Features of Hsp70s of Plasmodium Falciparum and Human Origins Biophysical Reviews. Jul, 2019 | Pubmed ID: 31280465 Proteomic Analysis of Plasmodium Falciparum Histone Deacetylase 1 Complex Proteins Experimental Parasitology. Mar, 2019 | Pubmed ID: 30682336 Heat Shock Proteins As Immunomodulants Molecules (Basel, Switzerland). Nov, 2018 | Pubmed ID: 30388847 Structural and Biochemical Characterization of Plasmodium Falciparum Hsp70-x Reveals Functional Versatility of Its C-terminal EEVN Motif Proteins. Nov, 2018 | Pubmed ID: 30183110 The Presence of Toxic and Non-Toxic Cyanobacteria in the Sediments of the Limpopo River Basin: Implications for Human Health Toxins. Jul, 2018 | Pubmed ID: 29970791 (-)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium Falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners Molecules (Basel, Switzerland). Dec, 2017 | Pubmed ID: 29206141 Extracts Obtained from Pterocarpus Angolensis DC and Ziziphus Mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function Molecules (Basel, Switzerland). Jul, 2017 | Pubmed ID: 28788073 Polymyxin B Inhibits the Chaperone Activity of Plasmodium Falciparum Hsp70 Cell Stress & Chaperones. Sep, 2017 | Pubmed ID: 28455613 Plasmodium Falciparum Heat Shock Protein 70 Lacks Immune Modulatory Activity Protein and Peptide Letters. 2017 | Pubmed ID: 28201964 Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium Falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia Coli PloS One. 2016 | Pubmed ID: 27031344 Plasmodium Falciparum Hsp70-z, an Hsp110 Homologue, Exhibits Independent Chaperone Activity and Interacts with Hsp70-1 in a Nucleotide-dependent Fashion Cell Stress & Chaperones. May, 2016 | Pubmed ID: 26894764 Plasmodium Falciparum Hop (PfHop) Interacts with the Hsp70 Chaperone in a Nucleotide-Dependent Fashion and Exhibits Ligand Selectivity PloS One. 2015 | Pubmed ID: 26267894 Overexpression, Purification and Characterisation of the Plasmodium Falciparum Hsp70-z (PfHsp70-z) Protein PloS One. 2015 | Pubmed ID: 26083397 DnaK Protein Alleviates Toxicity Induced by Citrate-coated Gold Nanoparticles in Escherichia Coli PloS One. 2015 | Pubmed ID: 25837593 Immunomodulatory Activity of Zinc Peroxide (ZnO₂) and Titanium Dioxide (TiO₂) Nanoparticles and Their Effects on DNA and Protein Integrity Toxicology Letters. May, 2014 | Pubmed ID: 24631018 Author Spotlight: Exploring Heat Shock Proteins in Malaria and Tuberculosis Infections Hloniphani Rachel Ncube1, Unarine Dali1, Tendamudzimu Harmfree Dongola1, Addmore Shonhai1 1Department of Biochemistry & Microbiology, University of Venda JoVE 66515 Biochimie
Author Spotlight: Exploring Heat Shock Proteins in Malaria and Tuberculosis Infections Hloniphani Rachel Ncube1, Unarine Dali1, Tendamudzimu Harmfree Dongola1, Addmore Shonhai1 1Department of Biochemistry & Microbiology, University of Venda JoVE 66515 Biochimie