Alexander G. Bassuk Department of Pediatrics University of Iowa Biography Publications Institution JoVE Articles Alexander G. Bassuk has not added a biography. If you are Alexander G. Bassuk and would like to personalize this page please email our Author Liaison for assistance. Publications Selective Neuroimmune Modulation by Type I Interferon Drives Neuropathology and Neurologic Dysfunction Following Traumatic Brain Injury Acta Neuropathologica Communications. Aug, 2023 | Pubmed ID: 37596685 Fast Detection and Quantification of Interictal Spikes and Seizures in a Rodent Model of Epilepsy Using an Automated Algorithm Bio-protocol. Mar, 2023 | Pubmed ID: 36968440 Downregulation of Oxidative Stress-mediated Glial Innate Immune Response Suppresses Seizures in a Fly Epilepsy Model Cell Reports. Jan, 2023 | Pubmed ID: 36641750 Human Brainstem and Cerebellum Atlas: Chemoarchitecture and Cytoarchitecture Paired to MRI The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2023 | Pubmed ID: 36442999 Lacosamide Decreases Neonatal Seizures Without Increasing Apoptosis Epilepsia. Dec, 2022 | Pubmed ID: 36168798 Calpains As Mechanistic Drivers and Therapeutic Targets for Ocular Disease Trends in Molecular Medicine. Aug, 2022 | Pubmed ID: 35641420 Proteomic Analysis of Autoimmune Retinopathy Implicates NrCAM As a Potential Biomarker Ophthalmology Science. Jun, 2022 | Pubmed ID: 35529077 Author Correction: Investigation of Cas9 Antibodies in the Human Eye Nature Communications. Apr, 2022 | Pubmed ID: 35414059 Investigation of Cas9 Antibodies in the Human Eye Nature Communications. Feb, 2022 | Pubmed ID: 35217666 Gene Therapy for Rett Syndrome Genes, Brain, and Behavior. Jan, 2022 | Pubmed ID: 34053173 The Opioid Antagonist Naltrexone Decreases Seizure-like Activity in Genetic and Chemically Induced Epilepsy Models Epilepsia Open. Sep, 2021 | Pubmed ID: 34664432 Introducing the Child Neurology Society Leadership, Diversity, Equity, and Inclusion Task Force Annals of Neurology. Oct, 2021 | Pubmed ID: 34288089 Traumatic Brain Injury Results in Unique Microglial and Astrocyte Transcriptomes Enriched for Type I Interferon Response Journal of Neuroinflammation. Jul, 2021 | Pubmed ID: 34225752 PRICKLE2 Revisited-further Evidence Implicating PRICKLE2 in Neurodevelopmental Disorders European Journal of Human Genetics : EJHG. Aug, 2021 | Pubmed ID: 34092786 Compound Heterozygous Variants in Progressive Myoclonus Epilepsy Journal of Neurogenetics. 2021 | Pubmed ID: 33970744 Visual Outcomes in Experimental Rodent Models of Blast-Mediated Traumatic Brain Injury Frontiers in Molecular Neuroscience. 2021 | Pubmed ID: 33935648 Structure-based Phylogeny Identifies Avoralstat As a TMPRSS2 Inhibitor That Prevents SARS-CoV-2 Infection in Mice The Journal of Clinical Investigation. May, 2021 | Pubmed ID: 33844653 Neuropathophysiological Mechanisms and Treatment Strategies for Post-traumatic Epilepsy Frontiers in Molecular Neuroscience. 2021 | Pubmed ID: 33708071 Peptidomimetics Therapeutics for Retinal Disease Biomolecules. Feb, 2021 | Pubmed ID: 33668179 Novel Inhibitory Brainstem Neurons with Selective Projections to Spinal Lamina I Reduce Both Pain and Itch The Journal of Comparative Neurology. Jun, 2021 | Pubmed ID: 33247430 Whole-Exome Sequencing of Patients With Posterior Segment Uveitis American Journal of Ophthalmology. Jan, 2021 | Pubmed ID: 32707200 Input-output Connections of LJA5 Prodynorphin Neurons The Journal of Comparative Neurology. Feb, 2021 | Pubmed ID: 32602558 PROGRESSION OF SCOTOPIC SINGLE-FLASH ELECTRORETINOGRAPHY IN THE STAGES OF CAPN5 VITREORETINOPATHY Retinal Cases & Brief Reports. Jul, 2021 | Pubmed ID: 30300311 Sex Does Not Influence Visual Outcomes After Blast-Mediated Traumatic Brain Injury but IL-1 Pathway Mutations Confer Partial Rescue Investigative Ophthalmology & Visual Science. Oct, 2020 | Pubmed ID: 33030508 A Missense Mutation in the MLKL Brace Region Promotes Lethal Neonatal Inflammation and Hematopoietic Dysfunction Nature Communications. Jun, 2020 | Pubmed ID: 32561755 Proteomic Analysis of Intermediate Uveitis Suggests Myeloid Cell Recruitment and Implicates IL-23 As a Therapeutic Target American Journal of Ophthalmology Case Reports. Jun, 2020 | Pubmed ID: 32274442 Phenotypic Variance in Calpain-5 Retinal Degeneration American Journal of Ophthalmology Case Reports. Jun, 2020 | Pubmed ID: 32274441 Identification of Chronic Brain Protein Changes and Protein Targets of Serum Auto-antibodies After Blast-mediated Traumatic Brain Injury Heliyon. Feb, 2020 | Pubmed ID: 32099918 Modulation of Post-Traumatic Immune Response Using the IL-1 Receptor Antagonist Anakinra for Improved Visual Outcomes Journal of Neurotrauma. Jun, 2020 | Pubmed ID: 32056479 Metabolite Therapy Guided by Liquid Biopsy Proteomics Delays Retinal Neurodegeneration EBioMedicine. Feb, 2020 | Pubmed ID: 32028070 Fundoscopy-directed Genetic Testing to Re-evaluate Negative Whole Exome Sequencing Results Orphanet Journal of Rare Diseases. Jan, 2020 | Pubmed ID: 32000842 Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants Cell Reports. Jan, 2020 | Pubmed ID: 31968260 A Mouse Model for Juvenile, Lateral Fluid Percussion Brain Injury Reveals Sex-Dependent Differences in Neuroinflammation and Functional Recovery Journal of Neurotrauma. Feb, 2020 | Pubmed ID: 31621484 Novel Mutations in the 3-box Motif of the BACK Domain of KLHL7 Associated with Nonsyndromic Autosomal Dominant Retinitis Pigmentosa Orphanet Journal of Rare Diseases. Dec, 2019 | Pubmed ID: 31856884 Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury Investigative Ophthalmology & Visual Science. Oct, 2019 | Pubmed ID: 31598627 Hypoxic Drive Caused Type 3 Neovascularization in a Preclinical Model of Exudative Age-related Macular Degeneration Human Molecular Genetics. Sep, 2019 | Pubmed ID: 31518400 CAPN5 Genetic Inactivation Phenotype Supports Therapeutic Inhibition Trials Human Mutation. Dec, 2019 | Pubmed ID: 31403230 CRISPR Base Editing in Induced Pluripotent Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 31250381 In Trans Variant Calling Reveals Enrichment for Compound Heterozygous Variants in Genes Involved in Neuronal Development and Growth Genetics Research. Jun, 2019 | Pubmed ID: 31190668 Gain-of-function Mutations in a Member of the Src Family Kinases Cause Autoinflammatory Bone Disease in Mice and Humans Proceedings of the National Academy of Sciences of the United States of America. Jun, 2019 | Pubmed ID: 31138708 Proteomic Insight into the Pathogenesis of CAPN5-vitreoretinopathy Scientific Reports. May, 2019 | Pubmed ID: 31110225 Mechanisms of Neurodegeneration in a Preclinical Autosomal Dominant Retinitis Pigmentosa Knock-in Model with a Rho Mutation Cellular and Molecular Life Sciences : CMLS. Sep, 2019 | Pubmed ID: 30976840 Drug Repositioning in Epilepsy Reveals Novel Antiseizure Candidates Annals of Clinical and Translational Neurology. Feb, 2019 | Pubmed ID: 30847362 Optical Coherence Tomography Angiography of RPGR-Associated Retinitis Pigmentosa Suggests Foveal Avascular Zone is a Biomarker for Vision Loss Ophthalmic Surgery, Lasers & Imaging Retina. Feb, 2019 | Pubmed ID: 30768229 The TFAP2A-IRF6-GRHL3 Genetic Pathway is Conserved in Neurulation Human Molecular Genetics. May, 2019 | Pubmed ID: 30689861 VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site Investigative Ophthalmology & Visual Science. 01, 2019 | Pubmed ID: 30657523 ProSave: an Application for Restoring Quantitative Data to Manipulated Subsets of Protein Lists Source Code for Biology and Medicine. 2018 | Pubmed ID: 30459825 Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease Translational Vision Science & Technology. Sep, 2018 | Pubmed ID: 30271679 Missense Mutation in SLIT2 Associated with Congenital Myopia, Anisometropia, Connective Tissue Abnormalities, and Obesity Orphanet Journal of Rare Diseases. Aug, 2018 | Pubmed ID: 30111362 Extracellular Superoxide Dismutase (SOD3) Regulates Oxidative Stress at the Vitreoretinal Interface Free Radical Biology & Medicine. 08, 2018 | Pubmed ID: 29940351 A De Novo Mutation in PRICKLE1 Associated with Myoclonic Epilepsy and Autism Spectrum Disorder Journal of Neurogenetics. Dec, 2018 | Pubmed ID: 29790814 Deferoxamine-induced Electronegative ERG Responses Documenta Ophthalmologica. Advances in Ophthalmology. 08, 2018 | Pubmed ID: 29770904 CRISPR GENOME SURGERY IN THE RETINA IN LIGHT OF OFF-TARGETING Retina (Philadelphia, Pa.). Aug, 2018 | Pubmed ID: 29746416 HTRA1, an Age-related Macular Degeneration Protease, Processes Extracellular Matrix Proteins EFEMP1 and TSP1 Aging Cell. Aug, 2018 | Pubmed ID: 29730901 Combined Blockade of Interleukin-1α and -1β Signaling Protects Mice from Cognitive Dysfunction After Traumatic Brain Injury ENeuro. 2018 | Pubmed ID: 29662944 Acute Vitreoretinal Trauma and Inflammation After Traumatic Brain Injury in Mice Annals of Clinical and Translational Neurology. Mar, 2018 | Pubmed ID: 29560370 Caring for Hereditary Childhood Retinal Blindness Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.). May-Jun, 2018 | Pubmed ID: 29536675 A Novel De Novo Mutation in a Patient with Inflammatory Vitreoretinopathy, Hearing Loss, and Developmental Delay Cold Spring Harbor Molecular Case Studies. Jun, 2018 | Pubmed ID: 29472286 Proteomic Analysis of the Human Retina Reveals Region-specific Susceptibilities to Metabolic- and Oxidative Stress-related Diseases PloS One. 2018 | Pubmed ID: 29466423 Autologous Stem Cell Therapy for Inherited and Acquired Retinal Disease Regenerative Medicine. Jan, 2018 | Pubmed ID: 29360008 Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and MTOR As a Therapeutic Target American Journal of Ophthalmology. 02, 2018 | Pubmed ID: 29246578 CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa: A Brief Methodology Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29188514 Therapeutic Drug Repositioning Using Personalized Proteomics of Liquid Biopsies JCI Insight. Dec, 2017 | Pubmed ID: 29263305 Gene Therapy Restores Mfrp and Corrects Axial Eye Length Scientific Reports. 11, 2017 | Pubmed ID: 29170418 Calpain-5 Gene Expression in the Mouse Eye and Brain BMC Research Notes. Nov, 2017 | Pubmed ID: 29157313 CRISPR-mediated Ophthalmic Genome Surgery Current Ophthalmology Reports. Sep, 2017 | Pubmed ID: 28966884 Prickle1 Regulates Neurite Outgrowth of Apical Spiral Ganglion Neurons but Not Hair Cell Polarity in the Murine Cochlea PloS One. 2017 | Pubmed ID: 28837644 Proteomic Analysis of Elevated Intraocular Pressure with Retinal Detachment American Journal of Ophthalmology Case Reports. Apr, 2017 | Pubmed ID: 28825049 Unexpected Mutations After CRISPR-Cas9 Editing in Vivo Nature Methods. May, 2017 | Pubmed ID: 28557981 Structural Modeling of a Novel SLC38A8 Mutation That Causes Foveal Hypoplasia Molecular Genetics & Genomic Medicine. May, 2017 | Pubmed ID: 28546991 Recessive Coding and Regulatory Mutations in FBLIM1 Underlie the Pathogenesis of Chronic Recurrent Multifocal Osteomyelitis (CRMO) PloS One. 2017 | Pubmed ID: 28301468 Biallelic Mutations in Neuromuscular Disease and Epileptic Encephalopathy Annals of Clinical and Translational Neurology. Jan, 2017 | Pubmed ID: 28078312 Mutation of Orthologous Prickle Genes Causes a Similar Epilepsy Syndrome in Flies and Humans Annals of Clinical and Translational Neurology. Sep, 2016 | Pubmed ID: 27648459 Patterning of Papillae on the Mouse Tongue: A System for the Quantitative Assessment of Planar Cell Polarity Signaling Developmental Biology. Nov, 2016 | Pubmed ID: 27612405 Reprogramming Towards Anabolism Impedes Degeneration in a Preclinical Model of Retinitis Pigmentosa Human Molecular Genetics. Oct, 2016 | Pubmed ID: 27516389 Catenin Delta-1 (CTNND1) Phosphorylation Controls the Mesenchymal to Epithelial Transition in Astrocytic Tumors Human Molecular Genetics. Oct, 2016 | Pubmed ID: 27516388 Small-angle X-ray Scattering of Calpain-5 Reveals a Highly Open Conformation Among Calpains Journal of Structural Biology. Dec, 2016 | Pubmed ID: 27474374 Secondary Glaucoma in CAPN5-associated Neovascular Inflammatory Vitreoretinopathy Clinical Ophthalmology (Auckland, N.Z.). 2016 | Pubmed ID: 27390515 CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2016 | Pubmed ID: 27203441 Neuroretinal Hypoxic Signaling in a New Preclinical Murine Model for Proliferative Diabetic Retinopathy Signal Transduction and Targeted Therapy. 2016 | Pubmed ID: 27195131 BESTROPHIN1 Mutations Cause Defective Chloride Conductance in Patient Stem Cell-derived RPE Human Molecular Genetics. Jul, 2016 | Pubmed ID: 27193166 Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses Investigative Ophthalmology & Visual Science. May, 2016 | Pubmed ID: 27152965 Response to Sandford Et al.: PRICKLE2 Variants in Epilepsy: A Call for Precision Medicine American Journal of Human Genetics. Mar, 2016 | Pubmed ID: 26942292 Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate PloS One. 2016 | Pubmed ID: 26934580 Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease JAMA Ophthalmology. Apr, 2016 | Pubmed ID: 26848019 Precision Medicine: Genetic Repair of Retinitis Pigmentosa in Patient-Derived Stem Cells Scientific Reports. Jan, 2016 | Pubmed ID: 26814166 A De Novo Mutation in PRICKLE1 in Fetal Agenesis of the Corpus Callosum and Polymicrogyria Journal of Neurogenetics. 2015 | Pubmed ID: 26727662 CAPN5 Mutation in Hereditary Uveitis: the R243L Mutation Increases Calpain Catalytic Activity and Triggers Intraocular Inflammation in a Mouse Model Human Molecular Genetics. Aug, 2015 | Pubmed ID: 25994508 Structural Modeling of a Novel CAPN5 Mutation That Causes Uveitis and Neovascular Retinal Detachment PloS One. 2015 | Pubmed ID: 25856303 Seizures Are Regulated by Ubiquitin-specific Peptidase 9 X-linked (USP9X), a De-ubiquitinase PLoS Genetics. Mar, 2015 | Pubmed ID: 25763846 Evaluating Familial Essential Tremor with Novel Genetic Approaches: Is It a Genotyping or Phenotyping Issue? Tremor and Other Hyperkinetic Movements (New York, N.Y.). 2014 | Pubmed ID: 25374765 P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function After Traumatic Brain Injury Cell Reports. Sep, 2014 | Pubmed ID: 25220467 Prickle Modulates Microtubule Polarity and Axonal Transport to Ameliorate Seizures in Flies Proceedings of the National Academy of Sciences of the United States of America. Jul, 2014 | Pubmed ID: 25024231 Functional Characterization of Prickle2 and BBS7 Identify Overlapping Phenotypes Yet Distinct Mechanisms Developmental Biology. Aug, 2014 | Pubmed ID: 24938409 Prickle1 is Necessary for the Caudal Migration of Murine Facial Branchiomotor Neurons Cell and Tissue Research. Sep, 2014 | Pubmed ID: 24927917 Defective Motile Cilia in Prickle2-deficient Mice Journal of Neurogenetics. Mar-Jun, 2014 | Pubmed ID: 24708399 Analysis of PRICKLE1 in Human Cleft Palate and Mouse Development Demonstrates Rare and Common Variants Involved in Human Malformations Molecular Genetics & Genomic Medicine. Mar, 2014 | Pubmed ID: 24689077 An International Effort Towards Developing Standards for Best Practices in Analysis, Interpretation and Reporting of Clinical Genome Sequencing Results in the CLARITY Challenge Genome Biology. 2014 | Pubmed ID: 24667040 A Novel RPGR Mutation Masquerading As Stargardt Disease The British Journal of Ophthalmology. May, 2014 | Pubmed ID: 24489377 Inflammasome-independent IL-1β Mediates Autoinflammatory Disease in Pstpip2-deficient Mice Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24395802 Functional Validation of a Human CAPN5 Exome Variant by Lentiviral Transduction into Mouse Retina Human Molecular Genetics. May, 2014 | Pubmed ID: 24381307 PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders PloS One. 2013 | Pubmed ID: 24312498 Exome Sequencing Reveals RAG1 Mutations in a Child with Autoimmunity and Sterile Chronic Multifocal Osteomyelitis Evolving into Disseminated Granulomatous Disease Journal of Clinical Immunology. Oct, 2013 | Pubmed ID: 24122031 Prickle1 Stunts Limb Growth Through Alteration of Cell Polarity and Gene Expression Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2013 | Pubmed ID: 23913870 Genome-wide Association Mapping in Dogs Enables Identification of the Homeobox Gene, NKX2-8, As a Genetic Component of Neural Tube Defects in Humans PLoS Genetics. 2013 | Pubmed ID: 23874236 Deletions of 16p11.2 and 19p13.2 in a Family with Intellectual Disability and Generalized Epilepsy American Journal of Medical Genetics. Part A. Jul, 2013 | Pubmed ID: 23686817 Mutations in Extracellular Matrix Genes NID1 and LAMC1 Cause Autosomal Dominant Dandy-Walker Malformation and Occipital Cephaloceles Human Mutation. Aug, 2013 | Pubmed ID: 23674478 Presence of Epilepsy-associated Variants in Large Exome Databases Journal of Neurogenetics. Jun, 2013 | Pubmed ID: 23527921 Mechanisms of Prickle1a Function in Zebrafish Epilepsy and Retinal Neurogenesis Disease Models & Mechanisms. May, 2013 | Pubmed ID: 23324328 Copy Number Variation Analysis Implicates the Cell Polarity Gene Glypican 5 As a Human Spina Bifida Candidate Gene Human Molecular Genetics. Mar, 2013 | Pubmed ID: 23223018 Monozygotic Twins with CAPN5 Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy Clinical Ophthalmology (Auckland, N.Z.). 2012 | Pubmed ID: 23271883 Calpain-5 Mutations Cause Autoimmune Uveitis, Retinal Neovascularization, and Photoreceptor Degeneration PLoS Genetics. 2012 | Pubmed ID: 23055945 Nuclear Localization of Prickle2 is Required to Establish Cell Polarity During Early Mouse Embryogenesis Developmental Biology. Apr, 2012 | Pubmed ID: 22333836 Identification and Characterization of Novel Rare Mutations in the Planar Cell Polarity Gene PRICKLE1 in Human Neural Tube Defects Human Mutation. Dec, 2011 | Pubmed ID: 21901791 Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans American Journal of Human Genetics. Feb, 2011 | Pubmed ID: 21276947 HeyL Promotes Neuronal Differentiation of Neural Progenitor Cells Journal of Neuroscience Research. Mar, 2011 | Pubmed ID: 21259317 Contribution of VANGL2 Mutations to Isolated Neural Tube Defects Clinical Genetics. Jul, 2011 | Pubmed ID: 20738329 Collagen XVIII Mutation in Knobloch Syndrome with Acute Lymphoblastic Leukemia American Journal of Medical Genetics. Part A. Nov, 2010 | Pubmed ID: 20799329 Genome-wide Copy Number Variation in Epilepsy: Novel Susceptibility Loci in Idiopathic Generalized and Focal Epilepsies PLoS Genetics. May, 2010 | Pubmed ID: 20502679 Genetic Basis of Neural Tube Defects Seminars in Pediatric Neurology. Sep, 2009 | Pubmed ID: 19778707 FOXC1 is Required for Normal Cerebellar Development and is a Major Contributor to Chromosome 6p25.3 Dandy-Walker Malformation Nature Genetics. Sep, 2009 | Pubmed ID: 19668217 Novel Mutations in VANGL1 in Neural Tube Defects Human Mutation. Jul, 2009 | Pubmed ID: 19319979 Infection-triggered Familial or Recurrent Cases of Acute Necrotizing Encephalopathy Caused by Mutations in a Component of the Nuclear Pore, RANBP2 American Journal of Human Genetics. Jan, 2009 | Pubmed ID: 19118815 A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-recessive Progressive Myoclonus Epilepsy-ataxia Syndrome American Journal of Human Genetics. Nov, 2008 | Pubmed ID: 18976727 आणविक विश्लेषण के लिए मानव जलीय और विट्रस तरल बायोप्सी की बायोबैंकिंग Julian Wolf1,2, Teja Chemudupati1,2, Aarushi Kumar1,2, Ditte K. Rasmussen1,2, Karen M. Wai2, Robert T. Chang2, Artis A. Montague2, Peter H. Tang3,4, Alexander G. Bassuk5,6,7, Antoine Dufour8,9, Prithvi Mruthrunjaya2, Vinit B. Mahajan1,2,10 1Molecular Surgery Laboratory, Stanford University, 2Department of Ophthalmology, Byers Eye Institute, Stanford University, 3Department of Ophthalmology and Visual Neurosciences, University of Minnesota, 4Retina Consultants of Minnesota, 5Department of Pediatrics, University of Iowa, 6Department of Neurology, University of Iowa, 7The Iowa Neuroscience Institute (INI), University of Iowa, 8Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, 9Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, 10Veterans Affairs Palo Alto Health Care System JoVE 65804 Médecine मानव रेटिना और RPE के विच्छेदन-Proteomic विश्लेषण के लिए धमनियां Thiago Cabral*1,2,7,8, Marcus A. Toral*3,4, Gabriel Velez3,4, James E. DiCarlo1,2, Anuradha M. Gore3, MaryAnn Mahajan3, Stephen H. Tsang1,2, Alexander G. Bassuk5,6, Vinit B. Mahajan3,9 1Barbara & Donald Jonas Stem Cell Laboratory, and Bernard & Shirlee Brown Glaucoma Laboratory, Department of Pathology & Cell Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, 2Edward S. Harkness Eye Institute, New York-Presbyterian Hospital, 3Omics Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University, 4Medical Scientist Training Program, University of Iowa, 5Department of Pediatrics, University of Iowa, 6Department of Neurology, University of Iowa, 7Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP), 8Department of Ophthalmology, Federal University of EspÍrito Santo (UFES), 9Palo Alto Veterans Administration, Palo Alto, CA JoVE 56203 Biochimie
आणविक विश्लेषण के लिए मानव जलीय और विट्रस तरल बायोप्सी की बायोबैंकिंग Julian Wolf1,2, Teja Chemudupati1,2, Aarushi Kumar1,2, Ditte K. Rasmussen1,2, Karen M. Wai2, Robert T. Chang2, Artis A. Montague2, Peter H. Tang3,4, Alexander G. Bassuk5,6,7, Antoine Dufour8,9, Prithvi Mruthrunjaya2, Vinit B. Mahajan1,2,10 1Molecular Surgery Laboratory, Stanford University, 2Department of Ophthalmology, Byers Eye Institute, Stanford University, 3Department of Ophthalmology and Visual Neurosciences, University of Minnesota, 4Retina Consultants of Minnesota, 5Department of Pediatrics, University of Iowa, 6Department of Neurology, University of Iowa, 7The Iowa Neuroscience Institute (INI), University of Iowa, 8Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, 9Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, 10Veterans Affairs Palo Alto Health Care System JoVE 65804 Médecine
मानव रेटिना और RPE के विच्छेदन-Proteomic विश्लेषण के लिए धमनियां Thiago Cabral*1,2,7,8, Marcus A. Toral*3,4, Gabriel Velez3,4, James E. DiCarlo1,2, Anuradha M. Gore3, MaryAnn Mahajan3, Stephen H. Tsang1,2, Alexander G. Bassuk5,6, Vinit B. Mahajan3,9 1Barbara & Donald Jonas Stem Cell Laboratory, and Bernard & Shirlee Brown Glaucoma Laboratory, Department of Pathology & Cell Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, 2Edward S. Harkness Eye Institute, New York-Presbyterian Hospital, 3Omics Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University, 4Medical Scientist Training Program, University of Iowa, 5Department of Pediatrics, University of Iowa, 6Department of Neurology, University of Iowa, 7Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP), 8Department of Ophthalmology, Federal University of EspÍrito Santo (UFES), 9Palo Alto Veterans Administration, Palo Alto, CA JoVE 56203 Biochimie