Andrew K. Godwin Department of Pathology and Laboratory Medicine University of Kansas Medical Center Biography Publications Institution JoVE Articles Andrew K. Godwin has not added a biography. If you are Andrew K. Godwin and would like to personalize this page please email our Author Liaison for assistance. Publications 19p13.1 is a Triple Negative-specific Breast Cancer Susceptibility Locus Cancer Research. Feb, 2012 | Pubmed ID: 22331459 Progranulin (GP88) Tumor Tissue Expression is Associated with Increased Risk of Recurrence in Breast Cancer Patients Diagnosed with Estrogen Receptor Positive Invasive Ductal Carcinoma Breast Cancer Research : BCR. Feb, 2012 | Pubmed ID: 22316048 Association Between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer JAMA : the Journal of the American Medical Association. Jan, 2012 | Pubmed ID: 22274685 Ovarian Cancer Susceptibility Alleles and Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers Human Mutation. Jan, 2012 | Pubmed ID: 22253144 The KL-VS Sequence Variant of Klotho and Cancer Risk in BRCA1 and BRCA2 Mutation Carriers Breast Cancer Research and Treatment. Jan, 2012 | Pubmed ID: 22212556 Pathology of Breast and Ovarian Cancers Among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2012 | Pubmed ID: 22144499 A Phase II Evaluation of Lapatinib in the Treatment of Persistent or Recurrent Epithelial Ovarian or Primary Peritoneal Carcinoma: A Gynecologic Oncology Group Study Gynecologic Oncology. Mar, 2012 | Pubmed ID: 22037316 An Integrative Genomic Approach Identifies P73 and P63 As Activators of MiR-200 MicroRNA Family Transcription Nucleic Acids Research. Jan, 2012 | Pubmed ID: 21917857 Interplay Between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer PLoS Biology. Nov, 2011 | Pubmed ID: 22110403 Bench to Bedside and Back Again: Personalizing Treatment for Patients with GIST Molecular Cancer Therapeutics. Nov, 2011 | Pubmed ID: 22072810 Common Breast Cancer Susceptibility Alleles Are Associated with Tumour Subtypes in BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 Breast Cancer Research : BCR. Nov, 2011 | Pubmed ID: 22053997 A Common Variant at the TERT-CLPTM1L Locus is Associated with Estrogen Receptor-negative Breast Cancer Nature Genetics. Dec, 2011 | Pubmed ID: 22037553 Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5 PLoS Genetics. Aug, 2011 | Pubmed ID: 21901109 Common Variants of the BRCA1 Wild-type Allele Modify the Risk of Breast Cancer in BRCA1 Mutation Carriers Human Molecular Genetics. Dec, 2011 | Pubmed ID: 21890493 Common Breast Cancer Susceptibility Loci Are Associated with Triple-negative Breast Cancer Cancer Research. Oct, 2011 | Pubmed ID: 21844186 Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence Cancer Research. Oct, 2011 | Pubmed ID: 21816908 Phase II Trial of the MTOR Inhibitor, Temsirolimus and Evaluation of Circulating Tumor Cells and Tumor Biomarkers in Persistent and Recurrent Epithelial Ovarian and Primary Peritoneal Malignancies: a Gynecologic Oncology Group Study Gynecologic Oncology. Oct, 2011 | Pubmed ID: 21752435 Serum Antimüllerian Hormone in Healthy Premenopausal Women Fertility and Sterility. Jun, 2011 | Pubmed ID: 21704216 Loss of A-type Lamin Expression Compromises Nuclear Envelope Integrity in Breast Cancer Chinese Journal of Cancer. Jun, 2011 | Pubmed ID: 21627864 Novel Surface Targets and Serum Biomarkers from the Ovarian Cancer Vasculature Cancer Biology & Therapy. Aug, 2011 | Pubmed ID: 21617380 Haplotype Structure in Ashkenazi Jewish BRCA1 and BRCA2 Mutation Carriers Human Genetics. Nov, 2011 | Pubmed ID: 21597964 Frequent Genetic Abnormalities of the PI3K/AKT Pathway in Primary Ovarian Cancer Predict Patient Outcome Genes, Chromosomes & Cancer. Aug, 2011 | Pubmed ID: 21563232 A Second Independent Locus Within DMRT1 is Associated with Testicular Germ Cell Tumor Susceptibility Human Molecular Genetics. Aug, 2011 | Pubmed ID: 21551455 Differential Expressions of Adhesive Molecules and Proteases Define Mechanisms of Ovarian Tumor Cell Matrix Penetration/invasion PloS One. 2011 | Pubmed ID: 21526198 PIK3R1 (p85α) is Somatically Mutated at High Frequency in Primary Endometrial Cancer Cancer Research. Jun, 2011 | Pubmed ID: 21478295 Expression of Siglec-11 by Human and Chimpanzee Ovarian Stromal Cells, with Uniquely Human Ligands: Implications for Human Ovarian Physiology and Pathology Glycobiology. Aug, 2011 | Pubmed ID: 21467073 Exploring the Link Between MORF4L1 and Risk of Breast Cancer Breast Cancer Research : BCR. 2011 | Pubmed ID: 21466675 Nuclear Envelope Structural Defects Cause Chromosomal Numerical Instability and Aneuploidy in Ovarian Cancer BMC Medicine. 2011 | Pubmed ID: 21439080 A Gynecologic Oncology Group Phase II Trial of the Protein Kinase C-beta Inhibitor, Enzastaurin and Evaluation of Markers with Potential Predictive and Prognostic Value in Persistent or Recurrent Epithelial Ovarian and Primary Peritoneal Malignancies Gynecologic Oncology. Jun, 2011 | Pubmed ID: 21414654 The Role of KRAS Rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2011 | Pubmed ID: 21385923 Ovarian Cancer Biomarker Performance in Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Specimens Cancer Prevention Research (Philadelphia, Pa.). Mar, 2011 | Pubmed ID: 21372036 Contribution of Large Genomic BRCA1 Alterations to Early-onset Breast Cancer Selected for Family History and Tumour Morphology: a Report from The Breast Cancer Family Registry Breast Cancer Research : BCR. 2011 | Pubmed ID: 21281505 A Unique Spectrum of Somatic PIK3CA (p110alpha) Mutations Within Primary Endometrial Carcinomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2011 | Pubmed ID: 21266528 Novel Glycan Biomarkers for the Detection of Lung Cancer Journal of Proteome Research. Apr, 2011 | Pubmed ID: 21214223 Protein Microarray Signature of Autoantibody Biomarkers for the Early Detection of Breast Cancer Journal of Proteome Research. Jan, 2011 | Pubmed ID: 20977275 Role of Gamma-synuclein in Microtubule Regulation Experimental Cell Research. Jun, 2011 | Pubmed ID: 20974125 Anti-human Embryonic Stem Cell Monoclonal Antibody Hesca-2 Binds to a Glycan Epitope Commonly Found on Carcinomas Stem Cells and Development. Mar, 2011 | Pubmed ID: 20887211 Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction Cancer Research. Dec, 2010 | Pubmed ID: 21118973 Enhancer of Zeste Homolog 2 Promotes the Proliferation and Invasion of Epithelial Ovarian Cancer Cells Molecular Cancer Research : MCR. Dec, 2010 | Pubmed ID: 21115743 Evidence for SMAD3 As a Modifier of Breast Cancer Risk in BRCA2 Mutation Carriers Breast Cancer Research : BCR. 2010 | Pubmed ID: 21114847 Common Genetic Variants and Modification of Penetrance of BRCA2-associated Breast Cancer PLoS Genetics. Oct, 2010 | Pubmed ID: 21060860 Alteration of Differentiation Potentials by Modulating GATA Transcription Factors in Murine Embryonic Stem Cells Stem Cells International. 2010 | Pubmed ID: 21048850 Upregulation of DLX5 Promotes Ovarian Cancer Cell Proliferation by Enhancing IRS-2-AKT Signaling Cancer Research. Nov, 2010 | Pubmed ID: 21045156 Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Nov, 2010 | Pubmed ID: 20978178 A Genome-wide Association Study Identifies Susceptibility Loci for Ovarian Cancer at 2q31 and 8q24 Nature Genetics. Oct, 2010 | Pubmed ID: 20852632 A Locus on 19p13 Modifies Risk of Breast Cancer in BRCA1 Mutation Carriers and is Associated with Hormone Receptor-negative Breast Cancer in the General Population Nature Genetics. Oct, 2010 | Pubmed ID: 20852631 A KRAS-variant in Ovarian Cancer Acts As a Genetic Marker of Cancer Risk Cancer Research. Aug, 2010 | Pubmed ID: 20647319 FOXA1 is an Essential Determinant of ERalpha Expression and Mammary Ductal Morphogenesis Development (Cambridge, England). Jun, 2010 | Pubmed ID: 20501593 LYN is a Mediator of Epithelial-mesenchymal Transition and a Target of Dasatinib in Breast Cancer Cancer Research. Mar, 2010 | Pubmed ID: 20215510 Nuclear Entry of Activated MAPK is Restricted in Primary Ovarian and Mammary Epithelial Cells PloS One. 2010 | Pubmed ID: 20174585 Frequent Downregulation of MiR-34 Family in Human Ovarian Cancers Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2010 | Pubmed ID: 20145172 Altered Gene Expression in Morphologically Normal Epithelial Cells from Heterozygous Carriers of BRCA1 or BRCA2 Mutations Cancer Prevention Research (Philadelphia, Pa.). Jan, 2010 | Pubmed ID: 20051372 Subtypes of Familial Breast Tumours Revealed by Expression and Copy Number Profiling Breast Cancer Research and Treatment. Oct, 2010 | Pubmed ID: 19960244 Regulation of MiR-200 Family MicroRNAs and ZEB Transcription Factors in Ovarian Cancer: Evidence Supporting a Mesothelial-to-epithelial Transition Gynecologic Oncology. Jan, 2010 | Pubmed ID: 19854497 Detection of Treatment-induced Changes in Signaling Pathways in Gastrointestinal Stromal Tumors Using Transcriptomic Data Cancer Research. Dec, 2009 | Pubmed ID: 19903850 Insulin-like Growth Factor Binding Protein-3 Has Dual Effects on Gastrointestinal Stromal Tumor Cell Viability and Sensitivity to the Anti-tumor Effects of Imatinib Mesylate in Vitro Molecular Cancer. 2009 | Pubmed ID: 19903356 Genetic Variation in Insulin-like Growth Factor Signaling Genes and Breast Cancer Risk Among BRCA1 and BRCA2 Carriers Breast Cancer Research : BCR. 2009 | Pubmed ID: 19843326 Prospective Case-control Study of Serum Mullerian Inhibiting Substance and Breast Cancer Risk Journal of the National Cancer Institute. Nov, 2009 | Pubmed ID: 19820206 Development and Characterization of Reference Materials for MTHFR, SERPINA1, RET, BRCA1, and BRCA2 Genetic Testing The Journal of Molecular Diagnostics : JMD. Nov, 2009 | Pubmed ID: 19767587 Gene Expression Signatures and Response to Imatinib Mesylate in Gastrointestinal Stromal Tumor Molecular Cancer Therapeutics. Aug, 2009 | Pubmed ID: 19671739 Common Variants in LSP1, 2q35 and 8q24 and Breast Cancer Risk for BRCA1 and BRCA2 Mutation Carriers Human Molecular Genetics. Nov, 2009 | Pubmed ID: 19656774 Loss of GATA4 and GATA6 Expression Specifies Ovarian Cancer Histological Subtypes and Precedes Neoplastic Transformation of Ovarian Surface Epithelia PloS One. 2009 | Pubmed ID: 19649254 High Density DNA Array Analysis Reveals Distinct Genomic Profiles in a Subset of Gastrointestinal Stromal Tumors Genes, Chromosomes & Cancer. Oct, 2009 | Pubmed ID: 19585585 Molecular and Cellular Biology. Sep, 2009 | Pubmed ID: 19581290 Clinical and Molecular Characteristics of Gastrointestinal Stromal Tumors in the Pediatric and Young Adult Population Current Oncology Reports. Jul, 2009 | Pubmed ID: 19508837 Biological Significance of Prolactin in Gynecologic Cancers Cancer Research. Jun, 2009 | Pubmed ID: 19491263 Common Variation in KITLG and at 5q31.3 Predisposes to Testicular Germ Cell Cancer Nature Genetics. Jul, 2009 | Pubmed ID: 19483682 Repertoire of MicroRNAs in Epithelial Ovarian Cancer As Determined by Next Generation Sequencing of Small RNA CDNA Libraries PloS One. 2009 | Pubmed ID: 19390579 Hereditary Ovarian Carcinoma: Heterogeneity, Molecular Genetics, Pathology, and Management Molecular Oncology. Apr, 2009 | Pubmed ID: 19383374 Phase II Trial of Single Agent Cetuximab in Patients with Persistent or Recurrent Epithelial Ovarian or Primary Peritoneal Carcinoma with the Potential for Dose Escalation to Rash Gynecologic Oncology. Apr, 2009 | Pubmed ID: 19162309 No Evidence That GATA3 Rs570613 SNP Modifies Breast Cancer Risk Breast Cancer Research and Treatment. Sep, 2009 | Pubmed ID: 19082709 Standard Operating Procedures for Serum and Plasma Collection: Early Detection Research Network Consensus Statement Standard Operating Procedure Integration Working Group Journal of Proteome Research. Jan, 2009 | Pubmed ID: 19072545 BRCA1 and BRCA2 Mutation Carriers in the Breast Cancer Family Registry: an Open Resource for Collaborative Research Breast Cancer Research and Treatment. Jul, 2009 | Pubmed ID: 18704680 Molecular Mechanisms of Action of Imatinib Mesylate in Human Ovarian Cancer: a Proteomic Analysis Cancer Genomics & Proteomics. May-Aug, 2008 | Pubmed ID: 18820368 The Insulin-like Growth Factor System As a Potential Therapeutic Target in Gastrointestinal Stromal Tumors Cell Cycle (Georgetown, Tex.). Oct, 2008 | Pubmed ID: 18818517 Insulin-like Growth Factor 1 Receptor is a Potential Therapeutic Target for Gastrointestinal Stromal Tumors Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008 | Pubmed ID: 18550829 Ovarian Normal and Tumor-associated Fibroblasts Retain in Vivo Stromal Characteristics in a 3-D Matrix-dependent Manner Gynecologic Oncology. Jul, 2008 | Pubmed ID: 18448156 Common Breast Cancer-predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers American Journal of Human Genetics. Apr, 2008 | Pubmed ID: 18355772 Perceived Stress is Associated with Impaired T-cell Response to HPV16 in Women with Cervical Dysplasia Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine. Feb, 2008 | Pubmed ID: 18347908 The Differential Role of L1 in Ovarian Carcinoma and Normal Ovarian Surface Epithelium Cancer Research. Feb, 2008 | Pubmed ID: 18281486 Promoter Hypermethylation of the PALB2 Susceptibility Gene in Inherited and Sporadic Breast and Ovarian Cancer Cancer Research. Feb, 2008 | Pubmed ID: 18281473 Allelic Imbalance in BRCA1 and BRCA2 Gene Expression is Associated with an Increased Breast Cancer Risk Human Molecular Genetics. May, 2008 | Pubmed ID: 18204050 Ovca1, a Candidate Gene of the Genetic Modifier of Tp53, Mop2, Affects Mouse Embryonic Lethality Genes, Chromosomes & Cancer. Apr, 2008 | Pubmed ID: 18181179 Liquid Chromatography Mass Spectrometry for Quantifying Plasma Lysophospholipids: Potential Biomarkers for Cancer Diagnosis Methods in Enzymology. 2007 | Pubmed ID: 17954226 Prostate Cancer Risk Assessment Program: a 10-year Update of Cancer Detection The Journal of Urology. Nov, 2007 | Pubmed ID: 17868726 MicroRNA-34b and MicroRNA-34c Are Targets of P53 and Cooperate in Control of Cell Proliferation and Adhesion-independent Growth Cancer Research. Sep, 2007 | Pubmed ID: 17823410 Genetic and Functional Analysis of CHEK2 (CHK2) Variants in Multiethnic Cohorts International Journal of Cancer. Journal International Du Cancer. Dec, 2007 | Pubmed ID: 17721994 Expression of Epiregulin and Amphiregulin and K-ras Mutation Status Predict Disease Control in Metastatic Colorectal Cancer Patients Treated with Cetuximab Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2007 | Pubmed ID: 17664471 Increased Expression of the Pro-protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2007 | Pubmed ID: 17641413 AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: a Consortium of Investigators of Modifiers of BRCA1/2 Study Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2007 | Pubmed ID: 17627006 Large Genomic Rearrangement in BRCA1 and BRCA2 and Clinical Characteristics of Men with Breast Cancer in the United States Clinical Breast Cancer. Jun, 2007 | Pubmed ID: 17592676 A Phase II and Pharmacodynamic Study of Gefitinib in Patients with Refractory or Recurrent Epithelial Ovarian Cancer Cancer. Apr, 2007 | Pubmed ID: 17330838 Nestin is Expressed in the Basal/myoepithelial Layer of the Mammary Gland and is a Selective Marker of Basal Epithelial Breast Tumors Cancer Research. Jan, 2007 | Pubmed ID: 17234757 Prominent Expression of Metalloproteinases in Early Stages of Ovarian Tumorigenesis Molecular Carcinogenesis. Feb, 2007 | Pubmed ID: 17131304 The Molecular Pathogenesis of Gastrointestinal Stromal Tumors Clinical Colorectal Cancer. Nov, 2006 | Pubmed ID: 17101067 Alterations of the Tumor Suppressor Gene ARLTS1 in Ovarian Cancer Cancer Research. Nov, 2006 | Pubmed ID: 17079447 BRCA1 and BRCA2 Mutation Carriers, Oral Contraceptive Use, and Breast Cancer Before Age 50 Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Oct, 2006 | Pubmed ID: 17021353 Involvement of RHO GTPases and ERK in Synuclein-gamma Enhanced Cancer Cell Motility International Journal of Oncology. Nov, 2006 | Pubmed ID: 17016652 No Increased Risk of Breast Cancer Associated with Alcohol Consumption Among Carriers of BRCA1 and BRCA2 Mutations Ages <50 Years Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Aug, 2006 | Pubmed ID: 16896052 Therapeutic Effect of Imatinib in Gastrointestinal Stromal Tumors: AKT Signaling Dependent and Independent Mechanisms Cancer Research. May, 2006 | Pubmed ID: 16707477 BRCC36 is Essential for Ionizing Radiation-induced BRCA1 Phosphorylation and Nuclear Foci Formation Cancer Research. May, 2006 | Pubmed ID: 16707425 Age-dependent Morphological Alterations of Human Ovaries from Populations with and Without BRCA Mutations Gynecologic Oncology. Nov, 2006 | Pubmed ID: 16698071 Intronic Alterations in BRCA1 and BRCA2: Effect on MRNA Splicing Fidelity and Expression Human Mutation. May, 2006 | Pubmed ID: 16619214 White Spot Syndrome Virus Open Reading Frame 222 Encodes a Viral E3 Ligase and Mediates Degradation of a Host Tumor Suppressor Via Ubiquitination Journal of Virology. Apr, 2006 | Pubmed ID: 16571805 Molecular Genetic Evidence That Endometriosis is a Precursor of Ovarian Cancer International Journal of Cancer. Journal International Du Cancer. Aug, 2006 | Pubmed ID: 16506222 BRCA1-associated Complexes: New Targets to Overcome Breast Cancer Radiation Resistance Expert Review of Anticancer Therapy. Feb, 2006 | Pubmed ID: 16445371 The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2006 | Pubmed ID: 16434590 Mass Spectrometric Identification of Serine Hydrolase OVCA2 in the Medulloblastoma Cell Line DAOY Cancer Letters. Sep, 2006 | Pubmed ID: 16368187 The Joint Effect of Smoking and AIB1 on Breast Cancer Risk in BRCA1 Mutation Carriers Carcinogenesis. Mar, 2006 | Pubmed ID: 16244359 Molecular Research Directions in the Management of Gastrointestinal Stromal Tumors Current Treatment Options in Oncology. Nov, 2005 | Pubmed ID: 16242052 Perception of Differentiation Cues by GATA Factors in Primitive Endoderm Lineage Determination of Mouse Embryonic Stem Cells Developmental Biology. Oct, 2005 | Pubmed ID: 16162334 Enhanced Counseling for Women Undergoing BRCA1/2 Testing: Impact on Subsequent Decision Making About Risk Reduction Behaviors Health Education & Behavior : the Official Publication of the Society for Public Health Education. Oct, 2005 | Pubmed ID: 16148211 Phase II Study of Gefitinib in Patients with Relapsed or Persistent Ovarian or Primary Peritoneal Carcinoma and Evaluation of Epidermal Growth Factor Receptor Mutations and Immunohistochemical Expression: a Gynecologic Oncology Group Study Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2005 | Pubmed ID: 16061871 Loss of TNF-alpha-regulated COX-2 Expression in Ovarian Cancer Cells Oncogene. Dec, 2005 | Pubmed ID: 16044148 WWOX Protein Expression Varies Among Ovarian Carcinoma Histotypes and Correlates with Less Favorable Outcome BMC Cancer. 2005 | Pubmed ID: 15982416 Analysis of KIT Mutations in Sporadic and Familial Gastrointestinal Stromal Tumors: Therapeutic Implications Through Protein Modeling Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2005 | Pubmed ID: 15897563 Familial Cancer Associated with a Polymorphism in ARLTS1 The New England Journal of Medicine. Apr, 2005 | Pubmed ID: 15843669 Linking Transcriptional Elongation and Messenger RNA Export to Metastatic Breast Cancers Cancer Research. Apr, 2005 | Pubmed ID: 15833825 Proteome Changes in Ovarian Epithelial Cells Derived from Women with BRCA1 Mutations and Family Histories of Cancer Molecular & Cellular Proteomics : MCP. Feb, 2005 | Pubmed ID: 15591324 Altered Gene Expression in Phenotypically Normal Renal Cells from Carriers of Tumor Suppressor Gene Mutations Cancer Biology & Therapy. Dec, 2004 | Pubmed ID: 15662135 AKT and MTOR Phosphorylation is Frequently Detected in Ovarian Cancer and Can Be Targeted to Disrupt Ovarian Tumor Cell Growth Oncogene. Jul, 2004 | Pubmed ID: 15208673 Identification of a Second G-C-rich Promoter Conserved in the Human, Murine and Rat Tumor Suppressor Genes HIC1 Oncogene. May, 2004 | Pubmed ID: 15007385 Tumor Necrosis Factor-alpha-induced Matrix Proteolytic Enzyme Production and Basement Membrane Remodeling by Human Ovarian Surface Epithelial Cells: Molecular Basis Linking Ovulation and Cancer Risk Cancer Research. Feb, 2004 | Pubmed ID: 14973065 Focus on Epithelial Ovarian Cancer Cancer Cell. Jan, 2004 | Pubmed ID: 14749123 Loss of Surface and Cyst Epithelial Basement Membranes and Preneoplastic Morphologic Changes in Prophylactic Oophorectomies Cancer. Dec, 2003 | Pubmed ID: 14669280 Altered Expression of the Septin Gene, SEPT9, in Ovarian Neoplasia The Journal of Pathology. Dec, 2003 | Pubmed ID: 14648661 Regulation of BRCC, a Holoenzyme Complex Containing BRCA1 and BRCA2, by a Signalosome-like Subunit and Its Role in DNA Repair Molecular Cell. Nov, 2003 | Pubmed ID: 14636569 The BCSC-1 Locus at Chromosome 11q23-q24 is a Candidate Tumor Suppressor Gene Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 14504409 Anomalous Expression of Epithelial Differentiation-determining GATA Factors in Ovarian Tumorigenesis Cancer Research. Aug, 2003 | Pubmed ID: 12941822 Response Markers and the Molecular Mechanisms of Action of Gleevec in Gastrointestinal Stromal Tumors Molecular Cancer Therapeutics. Aug, 2003 | Pubmed ID: 12939459 Parkin, a Gene Implicated in Autosomal Recessive Juvenile Parkinsonism, is a Candidate Tumor Suppressor Gene on Chromosome 6q25-q27 Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12719539 Expression of Constitutively Activated EGFRvIII in Non-small Cell Lung Cancer Cancer Science. Jan, 2003 | Pubmed ID: 12708474 Communication of BRCA1 and BRCA2 Results to At-risk Relatives: a Cancer Risk Assessment Program's Experience American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. May, 2003 | Pubmed ID: 12704633 Microarrays in Cancer: Research and Applications BioTechniques. Mar, 2003 | Pubmed ID: 12664679 Hypomethylation of the Synuclein Gamma Gene CpG Island Promotes Its Aberrant Expression in Breast Carcinoma and Ovarian Carcinoma Cancer Research. Feb, 2003 | Pubmed ID: 12566312 Dynamic Alterations of the Extracellular Environment of Ovarian Surface Epithelial Cells in Premalignant Transformation, Tumorigenicity, and Metastasis Cancer. Oct, 2002 | Pubmed ID: 12365030 DNA Array-based Method for Detection of Large Rearrangements in the BRCA1 Gene Genes, Chromosomes & Cancer. Nov, 2002 | Pubmed ID: 12353265 Ras/MAPK Pathway Confers Basement Membrane Dependence Upon Endoderm Differentiation of Embryonic Carcinoma Cells The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12145292 Elevated JNK Activation Contributes to the Pathogenesis of Human Brain Tumors Oncogene. Aug, 2002 | Pubmed ID: 12140754 Gamma-synuclein Promotes Cancer Cell Survival and Inhibits Stress- and Chemotherapy Drug-induced Apoptosis by Modulating MAPK Pathways The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12121974 Comparison of DNA- and RNA-based Methods for Detection of Truncating BRCA1 Mutations Human Mutation. Jul, 2002 | Pubmed ID: 12112659 Molecular Events Associated with Dysplastic Morphologic Transformation and Initiation of Ovarian Tumorigenicity Cancer. May, 2002 | Pubmed ID: 12015763 OVCA2 is Downregulated and Degraded During Retinoid-induced Apoptosis International Journal of Cancer. Journal International Du Cancer. May, 2002 | Pubmed ID: 11979432 Telomere Length Changes in Human Cancer Methods in Molecular Medicine. 2002 | Pubmed ID: 11901508 Decreased Expression of Retinol-binding Proteins is Associated with Malignant Transformation of the Ovarian Surface Epithelium DNA and Cell Biology. Jan, 2002 | Pubmed ID: 11879576 Proteolytic Cleavage of the CD44 Adhesion Molecule in Multiple Human Tumors The American Journal of Pathology. Feb, 2002 | Pubmed ID: 11839564 High-Throughput Screening of CAR T-Cell Constructs for Enhanced Cytotoxicity and Immunologic Memory (Video) | JoVE Siddharth Subham*1,2,3, John D. Jeppson*1, Benjamin K. Gibbs4, Jacqueline Babai2, Riza Alker1, Andrew K. Godwin4,5,6, David Akhavan1,2,3 1Department of Radiation Oncology, University of Kansas Cancer Center, 2Department of Cancer Biology, University of Kansas Cancer Center, 3BioEngineering Program, University of Kansas, 4Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 5University of Kansas Cancer Center, 6Kansas Institute for Precision Medicine, University of Kansas Medical Center JoVE 65560 Recherche en cancérologie In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian Cancer Alexis B. Cordero1, Youngjoo Kwon1, Xiang Hua2, Andrew K. Godwin1 1Department of Medical Oncology, Women's Cancer Program, 2Transgenic Mouse Facility, Fox Chase Cancer Center JoVE 2125 Biologie
High-Throughput Screening of CAR T-Cell Constructs for Enhanced Cytotoxicity and Immunologic Memory (Video) | JoVE Siddharth Subham*1,2,3, John D. Jeppson*1, Benjamin K. Gibbs4, Jacqueline Babai2, Riza Alker1, Andrew K. Godwin4,5,6, David Akhavan1,2,3 1Department of Radiation Oncology, University of Kansas Cancer Center, 2Department of Cancer Biology, University of Kansas Cancer Center, 3BioEngineering Program, University of Kansas, 4Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 5University of Kansas Cancer Center, 6Kansas Institute for Precision Medicine, University of Kansas Medical Center JoVE 65560 Recherche en cancérologie
In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian Cancer Alexis B. Cordero1, Youngjoo Kwon1, Xiang Hua2, Andrew K. Godwin1 1Department of Medical Oncology, Women's Cancer Program, 2Transgenic Mouse Facility, Fox Chase Cancer Center JoVE 2125 Biologie