Brian K. Kennedy Department of Biochemistry University of Washington Biography Publications Institution JoVE Articles Brian K. Kennedy has not added a biography. If you are Brian K. Kennedy and would like to personalize this page please email our Author Liaison for assistance. Publications A New Chronological Survival Assay in Mammalian Cell Culture Cell Cycle (Georgetown, Tex.). Jan, 2012 | Pubmed ID: 22214665 Genome-wide Analysis of Yeast Aging Sub-cellular Biochemistry. 2012 | Pubmed ID: 22094426 The Buck Institute: An Inside Look Cell Cycle (Georgetown, Tex.). Dec, 2011 | Pubmed ID: 22157188 Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces Cerevisiae PLoS Genetics. Sep, 2011 | Pubmed ID: 21931558 Sir2 Deletion Prevents Lifespan Extension in 32 Long-lived Mutants Aging Cell. Dec, 2011 | Pubmed ID: 21902802 Aged Worms Erase Epigenetic History Cell Metabolism. Aug, 2011 | Pubmed ID: 21803283 Trinations Aging Symposium Mechanisms of Ageing and Development. Jun-Jul, 2011 | Pubmed ID: 21771608 Decreased Proliferation Kinetics of Mouse Myoblasts Overexpressing FRG1 PloS One. 2011 | Pubmed ID: 21603621 A Genomic Analysis of Chronological Longevity Factors in Budding Yeast Cell Cycle (Georgetown, Tex.). May, 2011 | Pubmed ID: 21447998 Asymmetric Segregation: the Shape of Things to Come? Current Biology : CB. Feb, 2011 | Pubmed ID: 21334292 Quantitative Evidence for Early Life Fitness Defects from 32 Longevity-associated Alleles in Yeast Cell Cycle (Georgetown, Tex.). Jan, 2011 | Pubmed ID: 21191185 Hot Topics in Aging Research: Protein Translation and TOR Signaling, 2010 Aging Cell. Apr, 2011 | Pubmed ID: 21176090 TOR and Ageing: a Complex Pathway for a Complex Process Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jan, 2011 | Pubmed ID: 21115526 TOR on the Brain Experimental Gerontology. Feb-Mar, 2011 | Pubmed ID: 20849946 Old Yeast Can't Handle the Noise Molecular Cell. Sep, 2010 | Pubmed ID: 20832716 Downregulation of Lamin A by Tumor Suppressor AIMP3/p18 Leads to a Progeroid Phenotype in Mice Aging Cell. Oct, 2010 | Pubmed ID: 20726853 Progeria Syndromes and Ageing: What is the Connection? Nature Reviews. Molecular Cell Biology. Aug, 2010 | Pubmed ID: 20651707 Cell-extrinsic Defective Lymphocyte Development in Lmna(-/-) Mice PloS One. 2010 | Pubmed ID: 20405040 Translate This ... During Dietary Restriction Cell Metabolism. Oct, 2009 | Pubmed ID: 19808017 Attenuation of Age-related Metabolic Dysfunction in Mice with a Targeted Disruption of the Cbeta Subunit of Protein Kinase A The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Dec, 2009 | Pubmed ID: 19776218 Structural Changes to Monomeric CuZn Superoxide Dismutase Caused by the Familial Amyotrophic Lateral Sclerosis-associated Mutation A4V Biophysical Journal. Sep, 2009 | Pubmed ID: 19751676 Hot Topics in Aging Research: Protein Translation, 2009 Aging Cell. Dec, 2009 | Pubmed ID: 19747234 Ageing: A Midlife Longevity Drug? Nature. Jul, 2009 | Pubmed ID: 19606132 The TOR Pathway Comes of Age Biochimica Et Biophysica Acta. Oct, 2009 | Pubmed ID: 19539012 Histone H4 Lysine 16 Acetylation Regulates Cellular Lifespan Nature. Jun, 2009 | Pubmed ID: 19516333 A Molecular Mechanism of Chronological Aging in Yeast Cell Cycle (Georgetown, Tex.). Apr, 2009 | Pubmed ID: 19305133 A-type Nuclear Lamins Act As Transcriptional Repressors when Targeted to Promoters Experimental Cell Research. Apr, 2009 | Pubmed ID: 19272320 Shortest-path Network Analysis is a Useful Approach Toward Identifying Genetic Determinants of Longevity PloS One. 2008 | Pubmed ID: 19030232 Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by HTERT or Inactivation of P53 Molecular Biology of the Cell. Dec, 2008 | Pubmed ID: 18843043 Protein Translation, 2008 Aging Cell. Dec, 2008 | Pubmed ID: 18782345 Age- and Calorie-independent Life Span Extension from Dietary Restriction by Bacterial Deprivation in Caenorhabditis Elegans BMC Developmental Biology. 2008 | Pubmed ID: 18457595 Yeast Life Span Extension by Depletion of 60s Ribosomal Subunits is Mediated by Gcn4 Cell. Apr, 2008 | Pubmed ID: 18423200 Quantitative Evidence for Conserved Longevity Pathways Between Divergent Eukaryotic Species Genome Research. Apr, 2008 | Pubmed ID: 18340043 Dietary Restriction Suppresses Proteotoxicity and Enhances Longevity by an Hsf-1-dependent Mechanism in Caenorhabditis Elegans Aging Cell. Jun, 2008 | Pubmed ID: 18331616 A Method for High-throughput Quantitative Analysis of Yeast Chronological Life Span The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2008 | Pubmed ID: 18314444 Single-gene Deletions That Restore Mating Competence to Diploid Yeast FEMS Yeast Research. Mar, 2008 | Pubmed ID: 17995956 Protein Translation, 2007 Aging Cell. Dec, 2007 | Pubmed ID: 17941970 Evidence That Proteasome-dependent Degradation of the Retinoblastoma Protein in Cells Lacking A-type Lamins Occurs Independently of Gankyrin and MDM2 PloS One. 2007 | Pubmed ID: 17896003 Does Resveratrol Activate Yeast Sir2 in Vivo? Aging Cell. Aug, 2007 | Pubmed ID: 17635418 Recent Developments in Yeast Aging PLoS Genetics. May, 2007 | Pubmed ID: 17530929 Werner and Hutchinson-Gilford Progeria Syndromes: Mechanistic Basis of Human Progeroid Diseases Nature Reviews. Molecular Cell Biology. May, 2007 | Pubmed ID: 17450177 The Sensitivity of Yeast Mutants to Oleic Acid Implicates the Peroxisome and Other Processes in Membrane Function Genetics. Jan, 2007 | Pubmed ID: 17151231 Genome-wide Identification of Conserved Longevity Genes in Yeast and Worms Mechanisms of Ageing and Development. Jan, 2007 | Pubmed ID: 17126379 Sirtuin-independent Effects of Nicotinamide on Lifespan Extension from Calorie Restriction in Yeast Aging Cell. Dec, 2006 | Pubmed ID: 17129213 Lifespan Extension in Caenorhabditis Elegans by Complete Removal of Food Aging Cell. Dec, 2006 | Pubmed ID: 17081160 Aging: Progeria and the Lamin Connection Current Biology : CB. Aug, 2006 | Pubmed ID: 16920618 Sirtuins in Aging and Age-related Disease Cell. Jul, 2006 | Pubmed ID: 16873059 Stabilization of the Retinoblastoma Protein by A-type Nuclear Lamins is Required for INK4A-mediated Cell Cycle Arrest Molecular and Cellular Biology. Jul, 2006 | Pubmed ID: 16809772 Comment on "HST2 Mediates SIR2-independent Life-span Extension by Calorie Restriction" Science (New York, N.Y.). Jun, 2006 | Pubmed ID: 16741098 Lamin A/C and Emerin Are Critical for Skeletal Muscle Satellite Cell Differentiation Genes & Development. Feb, 2006 | Pubmed ID: 16481476 Extension of Chronological Life Span in Yeast by Decreased TOR Pathway Signaling Genes & Development. Jan, 2006 | Pubmed ID: 16418483 Increased Life Span Due to Calorie Restriction in Respiratory-deficient Yeast PLoS Genetics. Nov, 2005 | Pubmed ID: 16311627 Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16293764 The Enigmatic Role of Sir2 in Aging Cell. Nov, 2005 | Pubmed ID: 16286003 HIV Protease Inhibitors Block Adipocyte Differentiation Independently of Lamin A/C AIDS (London, England). Oct, 2005 | Pubmed ID: 16184025 Nuclear Tumor Suppressors in Space and Time Trends in Cell Biology. Jul, 2005 | Pubmed ID: 15936946 LMNA Mutations in Progeroid Syndromes Novartis Foundation Symposium. 2005 | Pubmed ID: 15773755 Genes Determining Yeast Replicative Life Span in a Long-lived Genetic Background Mechanisms of Ageing and Development. Apr, 2005 | Pubmed ID: 15722108 A-type Nuclear Lamins, Progerias and Other Degenerative Disorders Mechanisms of Ageing and Development. Apr, 2005 | Pubmed ID: 15722103 Substrate-specific Activation of Sirtuins by Resveratrol The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15684413 Large-scale Identification in Yeast of Conserved Ageing Genes Mechanisms of Ageing and Development. Jan, 2005 | Pubmed ID: 15610758 Sir2-independent Life Span Extension by Calorie Restriction in Yeast PLoS Biology. Sep, 2004 | Pubmed ID: 15328540 A-type Lamins Regulate Retinoblastoma Protein Function by Promoting Subnuclear Localization and Preventing Proteasomal Degradation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15210943 Nuclear Reorganization of Mammalian DNA Synthesis Prior to Cell Cycle Exit Molecular and Cellular Biology. Jan, 2004 | Pubmed ID: 14701733 LMNA Mutations in Atypical Werner's Syndrome Lancet. Aug, 2003 | Pubmed ID: 12927431 Mammalian Transcription Factors in Yeast: Strangers in a Familiar Land Nature Reviews. Molecular Cell Biology. Jan, 2002 | Pubmed ID: 11823797 Диапазона измерений репликативной Жизнь в почкующихся дрожжей Kristan K. Steffen1, Brian K. Kennedy1, Matt Kaeberlein2 1Department of Biochemistry, University of Washington, 2Department of Pathology, University of Washington JoVE 1209 Biologie
Диапазона измерений репликативной Жизнь в почкующихся дрожжей Kristan K. Steffen1, Brian K. Kennedy1, Matt Kaeberlein2 1Department of Biochemistry, University of Washington, 2Department of Pathology, University of Washington JoVE 1209 Biologie