Brian R. Christie Division of Medical Sciences University of Victoria Biography Publications Institution JoVE Articles Brian R. Christie has not added a biography. If you are Brian R. Christie and would like to personalize this page please email our Author Liaison for assistance. Publications Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure Nutrients. May, 2022 | Pubmed ID: 35631142 Author Correction: Exercise Hormone Irisin is a Critical Regulator of Cognitive Function Nature Metabolism. Oct, 2021 | Pubmed ID: 34621079 Prenatal Alcohol and Cannabis Exposure Can Have Opposing and Region-specific Effects on Parvalbumin Interneuron Numbers in the Hippocampus Alcoholism, Clinical and Experimental Research. Nov, 2021 | Pubmed ID: 34523142 Effects of Prenatal Ethanol Exposure on Choline-induced Long-term Depression in the Hippocampus Journal of Neurophysiology. Nov, 2021 | Pubmed ID: 34495785 Exercise Hormone Irisin is a Critical Regulator of Cognitive Function Nature Metabolism. Aug, 2021 | Pubmed ID: 34417591 Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice Molecular Neurobiology. Sep, 2021 | Pubmed ID: 34164760 AdipoRon Treatment Induces a Dose-Dependent Response in Adult Hippocampal Neurogenesis International Journal of Molecular Sciences. Feb, 2021 | Pubmed ID: 33669795 Understanding Changes in Hippocampal Interneurons Subtypes in the Pathogenesis of Alzheimer's Disease: A Systematic Review Brain Connectivity. Apr, 2021 | Pubmed ID: 33559520 Acute Δ9-tetrahydrocannabinol Prompts Rapid Changes in Cannabinoid CB Receptor Immunolabeling and Subcellular Structure in CA1 Hippocampus of Young Adult Male Mice The Journal of Comparative Neurology. Jun, 2021 | Pubmed ID: 33368252 Unlocking the Brain: A New Method for Western Blot Protein Detection from Fixed Brain Tissue Journal of Neuroscience Methods. Jan, 2021 | Pubmed ID: 33202258 Heading in the Right Direction: A Critical Review of Studies Examining the Effects of Heading in Soccer Players Journal of Neurotrauma. Jan, 2021 | Pubmed ID: 32883162 Effects of Ethanol on Synaptic Plasticity and NMDA Currents in the Juvenile Rat Dentate Gyrus Brain Plasticity (Amsterdam, Netherlands). Dec, 2020 | Pubmed ID: 33680851 Does Mild Traumatic Brain Injury Increase the Risk for Dementia? A Systematic Review and Meta-Analysis Journal of Alzheimer's Disease : JAD. 2020 | Pubmed ID: 33044182 Endocannabinoid Receptors Contribute Significantly to Multiple Forms of Long-term Depression in the Rat Dentate Gyrus Learning & Memory (Cold Spring Harbor, N.Y.). Sep, 2020 | Pubmed ID: 32817304 Interplay Between Hormones and Exercise on Hippocampal Plasticity Across the Lifespan Biochimica Et Biophysica Acta. Molecular Basis of Disease. Aug, 2020 | Pubmed ID: 32376385 A Systematic Review of the Effects of Perinatal Alcohol Exposure and Perinatal Marijuana Exposure on Adult Neurogenesis in the Dentate Gyrus Alcoholism, Clinical and Experimental Research. Jun, 2020 | Pubmed ID: 32246781 Hippocampal Cognitive Impairment in Juvenile Rats After Repeated Mild Traumatic Brain Injury Behavioural Brain Research. Jun, 2020 | Pubmed ID: 32184155 An Engineered Infected Epidermis Model for In Vitro Study of the Skin's Pro-Inflammatory Response Micromachines. Feb, 2020 | Pubmed ID: 32102205 Multiple Object Tracking Scores Predict Post-Concussion Status Years After Mild Traumatic Brain Injury Journal of Neurotrauma. Aug, 2020 | Pubmed ID: 31950862 Intermittent Ethanol Exposure During Adolescence Impairs Cannabinoid Type 1 Receptor-dependent Long-term Depression and Recognition Memory in Adult Mice Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jan, 2020 | Pubmed ID: 31569197 Modulation of Synaptic Plasticity by Exercise International Review of Neurobiology. 2019 | Pubmed ID: 31607359 A Rapid Neurological Assessment Protocol for Repeated Mild Traumatic Brain Injury in Awake Rats Current Protocols in Neuroscience. Sep, 2019 | Pubmed ID: 31532919 Impaired Bidirectional Synaptic Plasticity in Juvenile Offspring Following Prenatal Ethanol Exposure Alcoholism, Clinical and Experimental Research. Oct, 2019 | Pubmed ID: 31386206 Endocannabinoid Long-term Depression Revealed at Medial Perforant Path Excitatory Synapses in the Dentate Gyrus Neuropharmacology. Jul, 2019 | Pubmed ID: 31022405 Mild Closed-Head Injury in Conscious Rats Causes Transient Neurobehavioral and Glial Disturbances: A Novel Experimental Model of Concussion Journal of Neurotrauma. Jul, 2019 | Pubmed ID: 30843474 Fetal Alcohol Spectrum Disorder (FASD) Affects the Hippocampal Levels of Histone Variant H2A.Z-2 Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2019 | Pubmed ID: 30605356 Adolescent Ethanol Intake Alters Cannabinoid Type-1 Receptor Localization in Astrocytes of the Adult Mouse Hippocampus Addiction Biology. Mar, 2019 | Pubmed ID: 29168269 Fragile-X Syndrome Is Associated With NMDA Receptor Hypofunction and Reduced Dendritic Complexity in Mature Dentate Granule Cells Frontiers in Molecular Neuroscience. 2018 | Pubmed ID: 30705620 Effects of Voluntary Exercise on Cell Proliferation and Neurogenesis in the Dentate Gyrus of Adult FMR1 Knockout Mice Brain Plasticity (Amsterdam, Netherlands). Dec, 2018 | Pubmed ID: 30598869 Diffusion MRI Abnormalities in Adolescent Rats Given Repeated Mild Traumatic Brain Injury Annals of Clinical and Translational Neurology. Dec, 2018 | Pubmed ID: 30564624 Impaired Spatial Processing in a Mouse Model of Fragile X Syndrome Behavioural Brain Research. Sep, 2018 | Pubmed ID: 29778627 Repeated Mild Traumatic Brain Injury Can Cause Acute Neurologic Impairment Without Overt Structural Damage in Juvenile Rats PloS One. 2018 | Pubmed ID: 29738554 Chronic Minocycline Treatment Improves Hippocampal Neuronal Structure, NMDA Receptor Function, and Memory Processing in Fmr1 Knockout Mice Neurobiology of Disease. May, 2018 | Pubmed ID: 29367010 Effects of Isx-9 and Stress on Adult Hippocampal Neurogenesis: Experimental Considerations and Future Perspectives Neurogenesis (Austin, Tex.). 2017 | Pubmed ID: 28656155 Revisiting the Flip Side: Long-term Depression of Synaptic Efficacy in the Hippocampus Neuroscience and Biobehavioral Reviews. Sep, 2017 | Pubmed ID: 28624435 The Effects of Ethanol Exposure During Distinct Periods of Brain Development on Oxidative Stress in the Adult Rat Brain Alcoholism, Clinical and Experimental Research. Jan, 2017 | Pubmed ID: 27862017 Mild Traumatic Brain Injury Produces Long-Lasting Deficits in Synaptic Plasticity in the Female Juvenile Hippocampus Journal of Neurotrauma. Mar, 2017 | Pubmed ID: 27735217 The Potential for Animal Models to Provide Insight into Mild Traumatic Brain Injury: Translational Challenges and Strategies Neuroscience and Biobehavioral Reviews. May, 2017 | Pubmed ID: 27659125 Impaired Bidirectional NMDA Receptor Dependent Synaptic Plasticity in the Dentate Gyrus of Adult Female Fmr1 Heterozygous Knockout Mice Neurobiology of Disease. Dec, 2016 | Pubmed ID: 27659109 Chronic Corticosterone Administration Reduces Dendritic Complexity in Mature, But not Young Granule Cells in the Rat Dentate Gyrus Restorative Neurology and Neuroscience. Sep, 2016 | Pubmed ID: 27567758 ISX-9 Can Potentiate Cell Proliferation and Neuronal Commitment in the Rat Dentate Gyrus Neuroscience. Sep, 2016 | Pubmed ID: 27373772 Hippocampal Dysfunction and Cognitive Impairment in Fragile-X Syndrome Neuroscience and Biobehavioral Reviews. Sep, 2016 | Pubmed ID: 27345143 Chronic Minocycline Treatment Improves Social Recognition Memory in Adult Male Fmr1 Knockout Mice Behavioural Brain Research. Oct, 2016 | Pubmed ID: 27291517 The Effects of Hormones and Physical Exercise on Hippocampal Structural Plasticity Frontiers in Neuroendocrinology. Apr, 2016 | Pubmed ID: 26989000 Effects of Pre-natal Alcohol Exposure on Hippocampal Synaptic Plasticity: Sex, Age and Methodological Considerations Neuroscience and Biobehavioral Reviews. May, 2016 | Pubmed ID: 26906760 The Antidepressant-like Effect of Chronic Guanosine Treatment is Associated with Increased Hippocampal Neuronal Differentiation The European Journal of Neuroscience. Apr, 2016 | Pubmed ID: 26779605 Prenatal Ethanol Exposure Impairs Temporal Ordering Behaviours in Young Adult Rats Behavioural Brain Research. Feb, 2016 | Pubmed ID: 26632335 Time-Course Analysis of Protein and Lipid Oxidation in the Brains of Yac128 Huntington's Disease Transgenic Mice Rejuvenation Research. Apr, 2016 | Pubmed ID: 26371883 The Benefits of Exercise on Structural And Functional Plasticity in the Rodent Hippocampus of Different Disease Models Brain Plasticity (Amsterdam, Netherlands). Oct, 2015 | Pubmed ID: 29765836 Enhanced Corticosteroid Signaling Alters Synaptic Plasticity in the Dentate Gyrus in Mice Lacking the Fragile X Mental Retardation Protein Neurobiology of Disease. May, 2015 | Pubmed ID: 25731748 GluN2A-/- Mice Lack Bidirectional Synaptic Plasticity in the Dentate Gyrus and Perform Poorly on Spatial Pattern Separation Tasks Cerebral Cortex (New York, N.Y. : 1991). Aug, 2015 | Pubmed ID: 24554729 Physical Exercise-induced Hippocampal Neurogenesis and Antidepressant Effects Are Mediated by the Adipocyte Hormone Adiponectin Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25331877 A Comparison of the Different Animal Models of Fetal Alcohol Spectrum Disorders and Their Use in Studying Complex Behaviors Frontiers in Pediatrics. 2014 | Pubmed ID: 25232537 Deletion of the NMDA Receptor GluN2A Subunit Significantly Decreases Dendritic Growth in Maturing Dentate Granule Neurons PloS One. 2014 | Pubmed ID: 25083703 YAC128 Huntington's Disease Transgenic Mice Show Enhanced Short-term Hippocampal Synaptic Plasticity Early in the Course of the Disease Brain Research. Sep, 2014 | Pubmed ID: 24949563 Prenatal Ethanol Exposure Differentially Affects Hippocampal Neurogenesis in the Adolescent and Aged Brain Neuroscience. Jul, 2014 | Pubmed ID: 24846617 Physical Exercise-induced Adult Neurogenesis: a Good Strategy to Prevent Cognitive Decline in Neurodegenerative Diseases? BioMed Research International. 2014 | Pubmed ID: 24818140 The Role of Oxidative Stress in Huntington's Disease: Are Antioxidants Good Therapeutic Candidates? Current Drug Targets. Apr, 2014 | Pubmed ID: 24428525 Prenatal Ethanol (EtOH) Exposure Alters the Sensitivity of the Adult Dentate Gyrus to Acute EtOH Exposure Alcoholism, Clinical and Experimental Research. Jan, 2014 | Pubmed ID: 23915337 Effects of Ethanol Exposure During Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity Brain Sciences. Jul, 2013 | Pubmed ID: 24961522 Long-term Exercise is Needed to Enhance Synaptic Plasticity in the Hippocampus Learning & Memory (Cold Spring Harbor, N.Y.). Oct, 2013 | Pubmed ID: 24131795 Hippocampal Neurogenesis Levels Predict WATERMAZE Search Strategies in the Aging Brain PloS One. 2013 | Pubmed ID: 24086453 Impairments in Hippocampal Synaptic Plasticity Following Prenatal Ethanol Exposure Are Dependent on Glutathione Levels Hippocampus. Dec, 2013 | Pubmed ID: 23996467 Omega-3 Fatty Acids Can Reverse the Long-term Deficits in Hippocampal Synaptic Plasticity Caused by Prenatal Ethanol Exposure Neuroscience Letters. Sep, 2013 | Pubmed ID: 23872044 Omega-3 Supplementation Can Restore Glutathione Levels and Prevent Oxidative Damage Caused by Prenatal Ethanol Exposure The Journal of Nutritional Biochemistry. May, 2013 | Pubmed ID: 22841392 Differential Response of Hippocampal Subregions to Stress and Learning PloS One. 2012 | Pubmed ID: 23285257 Enhanced Deficits in Long-term Potentiation in the Adult Dentate Gyrus with 2nd Trimester Ethanol Consumption PloS One. 2012 | Pubmed ID: 23227262 Anxiety- and Depression-like Behaviors Are Accompanied by an Increase in Oxidative Stress in a Rat Model of Fetal Alcohol Spectrum Disorders: Protective Effects of Voluntary Physical Exercise Neuropharmacology. Mar, 2012 | Pubmed ID: 22019722 Neurogenesis in Huntington's Disease: Can Studying Adult Neurogenesis Lead to the Development of New Therapeutic Strategies? Brain Research. Aug, 2011 | Pubmed ID: 21742312 Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult PloS One. 2011 | Pubmed ID: 21655192 Voluntary Exercise Induces Adult Hippocampal Neurogenesis and BDNF Expression in a Rodent Model of Fetal Alcohol Spectrum Disorders The European Journal of Neuroscience. May, 2011 | Pubmed ID: 21535455 The Role of Oxidative Stress in Fetal Alcohol Spectrum Disorders Brain Research Reviews. Jun, 2011 | Pubmed ID: 21315761 Altered Adult Hippocampal Neuronal Maturation in a Rat Model of Fetal Alcohol Syndrome Brain Research. Apr, 2011 | Pubmed ID: 21303667 Altered Adult Hippocampal Neurogenesis in the YAC128 Transgenic Mouse Model of Huntington Disease Neurobiology of Disease. Feb, 2011 | Pubmed ID: 20875859 Running Reduces Stress and Enhances Cell Genesis in Aged Mice Neurobiology of Aging. Dec, 2011 | Pubmed ID: 20106549 Hippocampal Cell Loss and Neurogenesis After Fetal Alcohol Exposure: Insights from Different Rodent Models Brain Research Reviews. Sep, 2010 | Pubmed ID: 20471420 Characterization of the Neurogenesis Quiescent Zone in the Rodent Brain: Effects of Age and Exercise The European Journal of Neuroscience. Mar, 2010 | Pubmed ID: 20374281 Endogenous Cannabinoid Signaling is Required for Voluntary Exercise-induced Enhancement of Progenitor Cell Proliferation in the Hippocampus Hippocampus. Apr, 2010 | Pubmed ID: 19489006 NGF is Essential for Hippocampal Plasticity and Learning The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2009 | Pubmed ID: 19726646 Cognition, Learning Behaviour and Hippocampal Synaptic Plasticity Are Not Disrupted in Mice Over-expressing the Cholesterol Transporter ABCG1 Lipids in Health and Disease. Feb, 2009 | Pubmed ID: 19239689 Stress Differentially Regulates the Effects of Voluntary Exercise on Cell Proliferation in the Dentate Gyrus of Mice Hippocampus. Oct, 2009 | Pubmed ID: 18958850 Exercising Our Brains: How Physical Activity Impacts Synaptic Plasticity in the Dentate Gyrus Neuromolecular Medicine. 2008 | Pubmed ID: 18535925 Long-term Depression in Vivo: Effects of Sex, Stress, Diet, and Prenatal Ethanol Exposure Hippocampus. 2008 | Pubmed ID: 18240319 Оценка изменений синаптической пластичности с использованием модели легкой черепно-мозговой травмы в сознании Brian R. Christie1,2, Allyson Gross1, Annika Willoughby1, Erin Grafe1, Justin Brand1, Emily Bosdachin1, Hannah M. O. Reid1, Crystal Acosta1, Eric Eyolfson1 1Division of Medical Sciences, University of Victoria, 2Island Medical Program, University of British Columbia JoVE 64592 Neurosciences
Оценка изменений синаптической пластичности с использованием модели легкой черепно-мозговой травмы в сознании Brian R. Christie1,2, Allyson Gross1, Annika Willoughby1, Erin Grafe1, Justin Brand1, Emily Bosdachin1, Hannah M. O. Reid1, Crystal Acosta1, Eric Eyolfson1 1Division of Medical Sciences, University of Victoria, 2Island Medical Program, University of British Columbia JoVE 64592 Neurosciences
