Claire Usal Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM, Université de Nantes Biography Publications Institution JoVE Articles Claire Usal has not added a biography. If you are Claire Usal and would like to personalize this page please email our Author Liaison for assistance. Publications Comparative Analysis of PiggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats Scientific Reports. Aug, 2016 | Pubmed ID: 27530248 A Rapid and Cost-Effective Method for Genotyping Genome-Edited Animals: A Heteroduplex Mobility Assay Using Microfluidic Capillary Electrophoresis Journal of Genetics and Genomics = Yi Chuan Xue Bao. May, 2016 | Pubmed ID: 27209567 Genome Editing in Rats Using TALE Nucleases Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26443226 Homology-directed Repair in Rodent Zygotes Using Cas9 and TALEN Engineered Proteins Scientific Reports. Oct, 2015 | Pubmed ID: 26442875 Regulatory B Cells with a Partial Defect in CD40 Signaling and Overexpressing Granzyme B Transfer Allograft Tolerance in Rodents Journal of Immunology (Baltimore, Md. : 1950). Nov, 2015 | Pubmed ID: 26432892 IL-34 is a Treg-specific Cytokine and Mediates Transplant Tolerance The Journal of Clinical Investigation. Oct, 2015 | Pubmed ID: 26389674 Transgenic Animals and Genetic Engineering Techniques. Nantes, France, 2-3 July, 2015 Transgenic Research. Dec, 2015 | Pubmed ID: 26358113 Efficient Gene Targeting by Homology-directed Repair in Rat Zygotes Using TALE Nucleases Genome Research. Aug, 2014 | Pubmed ID: 24989021 Gene Targeting in Rats Using Transcription Activator-like Effector Nucleases Methods (San Diego, Calif.). Aug, 2014 | Pubmed ID: 24583114 Technical Advances in the Generation of Transgenic Animals and in Their Applications. Nantes, France, June 7th 2013 Transgenic Research. Oct, 2013 | Pubmed ID: 23907705 Generation of Rag1-knockout Immunodeficient Rats and Mice Using Engineered Meganucleases FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2013 | Pubmed ID: 23150522 Immunoregulatory Function of IL-27 and TGF-β1 in Cardiac Allograft Transplantation Transplantation. Aug, 2012 | Pubmed ID: 22790384 Control of Transplant Tolerance and Intragraft Regulatory T Cell Localization by Myeloid-derived Suppressor Cells and CCL5 Journal of Immunology (Baltimore, Md. : 1950). May, 2012 | Pubmed ID: 22450806 Effects of BCL-2 Over-expression on B Cells in Transgenic Rats and Rat Hybridomas International Immunology. Oct, 2011 | Pubmed ID: 21930595 Knockout Rats Generated by Embryo Microinjection of TALENs Nature Biotechnology. Aug, 2011 | Pubmed ID: 21822240 Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease Parkinson's Disease. 2011 | Pubmed ID: 21766003 TNF Blockade Abrogates the Induction of T Cell-dependent Humoral Responses in an Allotransplantation Model Journal of Leukocyte Biology. Aug, 2011 | Pubmed ID: 21562051 Development of Initial Idiopathic Nephrotic Syndrome and Post-transplantation Recurrence: Evidence of the Same Biological Entity Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. May, 2011 | Pubmed ID: 20935016 Characterization of Immunoglobulin Heavy Chain Knockout Rats European Journal of Immunology. Oct, 2010 | Pubmed ID: 21038471 Lentiviral Vectors That Express UGT1A1 in Liver and Contain MiR-142 Target Sequences Normalize Hyperbilirubinemia in Gunn Rats Gastroenterology. Sep, 2010 | Pubmed ID: 20546738 Mechanism and Localization of CD8 Regulatory T Cells in a Heart Transplant Model of Tolerance Journal of Immunology (Baltimore, Md. : 1950). Jul, 2010 | Pubmed ID: 20543104 Immunoproteasome Beta Subunit 10 is Increased in Chronic Antibody-mediated Rejection Kidney International. May, 2010 | Pubmed ID: 20182416 Analysis by Quantitative PCR of Zygosity in Genetically Modified Organisms Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20013240 Generation of Gene-specific Mutated Rats Using Zinc-finger Nucleases Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20013236 The Use of Lentiviral Vectors to Obtain Transgenic Rats Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20013229 Generation of Transgenic Rats by Microinjection of Short DNA Fragments Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20013227 "Transgenesis, Recent Technical Developments and Applications" Nantes, 8th June 2009 Transgenic Research. Aug, 2010 | Pubmed ID: 19882223 Zinc-finger Nucleases: a Powerful Tool for Genetic Engineering of Animals Transgenic Research. Jun, 2010 | Pubmed ID: 19821047 Autoimmune Responses Against Renal Tissue Proteins in Long-term Surviving Allograft Recipients Transplant International : Official Journal of the European Society for Organ Transplantation. Nov, 2009 | Pubmed ID: 19624494 Induction of T Regulatory Cells Attenuates Idiopathic Nephrotic Syndrome Journal of the American Society of Nephrology : JASN. Jan, 2009 | Pubmed ID: 19020006 Myeloid-derived Suppressor Cells Accumulate in Kidney Allograft Tolerance and Specifically Suppress Effector T Cell Expansion Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18523253 Implication of Matrix Metalloproteinase 7 and the Noncanonical Wingless-type Signaling Pathway in a Model of Kidney Allograft Tolerance Induced by the Administration of Anti-donor Class II Antibodies Journal of Immunology (Baltimore, Md. : 1950). Feb, 2008 | Pubmed ID: 18209025 Depletion of LAG-3 Positive Cells in Cardiac Allograft Reveals Their Role in Rejection and Tolerance Transplantation. Dec, 2007 | Pubmed ID: 18091527 Anti-CD28 Antibodies Modify Regulatory Mechanisms and Reinforce Tolerance in CD40Ig-treated Heart Allograft Recipients Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056359 Nitric Oxide and Indoleamine 2,3-dioxygenase Mediate CTLA4Ig-induced Survival in Heart Allografts in Rats Transplantation. Oct, 2007 | Pubmed ID: 17989614 CD40Ig Treatment Results in Allograft Acceptance Mediated by CD8CD45RC T Cells, IFN-gamma, and Indoleamine 2,3-dioxygenase The Journal of Clinical Investigation. Apr, 2007 | Pubmed ID: 17404623 Dominant Tolerance to Kidney Allografts Induced by Anti-donor MHC Class II Antibodies: Cooperation Between T and Non-T CD103+ Cells Journal of Immunology (Baltimore, Md. : 1950). Apr, 2006 | Pubmed ID: 16547225 Transgenic Modifications of the Rat Genome Transgenic Research. Oct, 2005 | Pubmed ID: 16245144 Renal Macrophage Activation and Th2 Polarization Precedes the Development of Nephrotic Syndrome in Buffalo/Mna Rats Kidney International. Nov, 2005 | Pubmed ID: 16221207 Inhibition of Chronic Rejection and Development of Tolerogenic T Cells After ICOS-ICOSL and CD40-CD40L Co-stimulation Blockade Transplantation. Aug, 2005 | Pubmed ID: 16220623 Anti-CD28 Antibody-induced Kidney Allograft Tolerance Related to Tryptophan Degradation and TCR Class II B7 Regulatory Cells American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Oct, 2005 | Pubmed ID: 16162181 Exhaustive Depletion of Graft Resident Dendritic Cells: Marginally Delayed Rejection but Strong Alteration of Graft Infiltration Transplantation. Aug, 2005 | Pubmed ID: 16123726 Inhibition of Chronic Rejection and Development of Tolerogenic T Cells After ICOS-ICOSL and CD40-CD40L Co-stimulation Blockade Transplantation. Jul, 2005 | Pubmed ID: 16041272 The Effect of a First Kidney Transplant on a Subsequent Transplant Outcome: an Experimental and Clinical Study Kidney International. Jun, 2005 | Pubmed ID: 15882281 Presentation of Donor Major Histocompatibility Complex Antigens by Bone Marrow Dendritic Cell-derived Exosomes Modulates Allograft Rejection Transplantation. Nov, 2003 | Pubmed ID: 14657694 Induction of Donor-specific Allograft Tolerance by Short-term Treatment with LF15-0195 After Transplantation. Evidence for a Direct Effect on T-cell Differentiation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Sep, 2002 | Pubmed ID: 12243495 Role for Thymic and Splenic Regulatory CD4+ T Cells Induced by Donor Dendritic Cells in Allograft Tolerance by LF15-0195 Treatment Journal of Immunology (Baltimore, Md. : 1950). May, 2002 | Pubmed ID: 11994458 Extrarenal Effects on the Pathogenesis and Relapse of Idiopathic Nephrotic Syndrome in Buffalo/Mna Rats The Journal of Clinical Investigation. Feb, 2002 | Pubmed ID: 11854321 In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients Séverine Bézie1,2, Claire Usal1,2, Carole Guillonneau1,2 1Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, Université de Nantes, 2Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes JoVE 55510 Immunologie et Infection
In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients Séverine Bézie1,2, Claire Usal1,2, Carole Guillonneau1,2 1Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, Université de Nantes, 2Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes JoVE 55510 Immunologie et Infection