Daniel A. Harrington Department of BioSciences Rice University Biography Publications Institution JoVE Articles Daniel A. Harrington has not added a biography. If you are Daniel A. Harrington and would like to personalize this page please email our Author Liaison for assistance. Publications Cabozantinib Reverses Renal Cell Carcinoma-mediated Osteoblast Inhibition in Three-dimensional Coculture and Reduces Bone Osteolysis Molecular Cancer Therapeutics. 06, 2020 | Pubmed ID: 32220969 Dynamic Assembly of Human Salivary Stem/Progenitor Microstructures Requires Coordinated αβ Integrin-Mediated Motility Frontiers in Cell and Developmental Biology. Month, 2019 | Pubmed ID: 31750298 Perlecan Domain I Gradients Establish Stable Biomimetic Heparin Binding Growth Factor Gradients for Cell Migration in Hydrogels Acta Biomaterialia. 10, 2019 | Pubmed ID: 31351252 Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells Scientific Reports. 05, 2018 | Pubmed ID: 29740048 Bottom-up Assembly of Salivary Gland Microtissues for Assessing Myoepithelial Cell Function Biomaterials. Oct, 2017 | Pubmed ID: 28734180 Primary Salivary Human Stem/Progenitor Cells Undergo Microenvironment-Driven Acinar-Like Differentiation in Hyaluronate Hydrogel Culture Stem Cells Translational Medicine. 01, 2017 | Pubmed ID: 28170182 Peptide Amphiphile Nanofiber Hydrogel Delivery of Sonic Hedgehog Protein to the Cavernous Nerve to Promote Regeneration and Prevent Erectile Dysfunction Nanomedicine : Nanotechnology, Biology, and Medicine. 01, 2017 | Pubmed ID: 27609775 Tuning Hydrogel Properties to Promote the Assembly of Salivary Gland Spheroids in 3D ACS Biomaterials Science & Engineering. Dec, 2016 | Pubmed ID: 27990487 Sustained Delivery of Recombinant Human Bone Morphogenetic Protein-2 from Perlecan Domain I - Functionalized Electrospun Poly (ε-caprolactone) Scaffolds for Bone Regeneration Journal of Experimental Orthopaedics. Dec, 2016 | Pubmed ID: 27714703 Heralding a New Paradigm in 3D Tumor Modeling Biomaterials. 11, 2016 | Pubmed ID: 27639438 Biomaterials-based Strategies for Salivary Gland Tissue Regeneration Biomaterials Science. Apr, 2016 | Pubmed ID: 26878077 Sonic Hedgehog Delivery from Self-assembled Nanofiber Hydrogels Reduces the Fibrotic Response in Models of Erectile Dysfunction Acta Biomaterialia. Mar, 2016 | Pubmed ID: 26776147 A 3D In vitro Model of Patient-derived Prostate Cancer Xenograft for Controlled Interrogation of In vivo Tumor-stromal Interactions Biomaterials. Jan, 2016 | Pubmed ID: 26599623 Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures Advanced Healthcare Materials. Aug, 2015 | Pubmed ID: 26059746 Three-dimensional (3D) Culture of Bone-derived Human 786-O Renal Cell Carcinoma Retains Relevant Clinical Characteristics of Bone Metastases Cancer Letters. Aug, 2015 | Pubmed ID: 26004343 Hydrogel-based 3D Model of Patient-derived Prostate Xenograft Tumors Suitable for Drug Screening Molecular Pharmaceutics. Jul, 2014 | Pubmed ID: 24779589 A Hydrogel-based Tumor Model for the Evaluation of Nanoparticle-based Cancer Therapeutics Biomaterials. Mar, 2014 | Pubmed ID: 24447463 Border Patrol: Insights into the Unique Role of Perlecan/heparan Sulfate Proteoglycan 2 at Cell and Tissue Borders Matrix Biology : Journal of the International Society for Matrix Biology. Feb, 2014 | Pubmed ID: 24001398 A Novel in Vivo Model for Evaluating Functional Restoration of a Tissue-engineered Salivary Gland The Laryngoscope. Feb, 2014 | Pubmed ID: 23832678 Implantable Three-dimensional Salivary Spheroid Assemblies Demonstrate Fluid and Protein Secretory Responses to Neurotransmitters Tissue Engineering. Part A. Jul, 2013 | Pubmed ID: 23442148 Recreating the Tumor Microenvironment in a Bilayer, Hyaluronic Acid Hydrogel Construct for the Growth of Prostate Cancer Spheroids Biomaterials. Dec, 2012 | Pubmed ID: 22999468 Hyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks Soft Matter. Month, 2012 | Pubmed ID: 22419946 Regeneration of the Cavernous Nerve by Sonic Hedgehog Using Aligned Peptide Amphiphile Nanofibers Biomaterials. Feb, 2011 | Pubmed ID: 20971506 Peptide Amphiphile Nanofiber Delivery of Sonic Hedgehog Protein to Reduce Smooth Muscle Apoptosis in the Penis After Cavernous Nerve Resection The Journal of Sexual Medicine. Jan, 2011 | Pubmed ID: 20807324 Enhanced Viability for Ex vivo 3D Hydrogel Cultures of Patient-Derived Xenografts in a Perfused Microfluidic Platform Lindsey K. Sablatura1, Kristin M. Bircsak2, Peter Shepherd3, Karla Queiroz4, Mary C. Farach-Carson1,5,6, Pamela E. Constantinou1,7, Anthony Saleh2, Nora Navone3, Daniel A. Harrington1,5,6 1Department of BioSciences, Rice University, 2Mimetas US Inc, 3Department of Genitourinary Medical Oncology Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, 4Mimetas B.V., 5Department of Bioengineering, Rice University, 6Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center, 7Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center JoVE 60872 Recherche en cancérologie
Enhanced Viability for Ex vivo 3D Hydrogel Cultures of Patient-Derived Xenografts in a Perfused Microfluidic Platform Lindsey K. Sablatura1, Kristin M. Bircsak2, Peter Shepherd3, Karla Queiroz4, Mary C. Farach-Carson1,5,6, Pamela E. Constantinou1,7, Anthony Saleh2, Nora Navone3, Daniel A. Harrington1,5,6 1Department of BioSciences, Rice University, 2Mimetas US Inc, 3Department of Genitourinary Medical Oncology Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, 4Mimetas B.V., 5Department of Bioengineering, Rice University, 6Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center, 7Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center JoVE 60872 Recherche en cancérologie