David K. C. Cooper Xenotransplantation Program/Department of Surgery University of Alabama at Birmingham Biography Publications Institution JoVE Articles David K. C. Cooper has not added a biography. If you are David K. C. Cooper and would like to personalize this page please email our Author Liaison for assistance. Publications Pig-to-Macaque Islet Xenotransplantation Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32002916 Introduction: The Present Status of Xenotransplantation Research Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32002898 Meta-analysis of Public Perception Toward Xenotransplantation Xenotransplantation. Jan, 2020 | Pubmed ID: 31957115 Clinical Pig Kidney Xenotransplantation: How Close Are We? Journal of the American Society of Nephrology : JASN. Jan, 2020 | Pubmed ID: 31792154 Is Interleukin-6 Receptor Blockade (tocilizumab) Beneficial or Detrimental to Pig-to-baboon Organ Xenotransplantation? American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2019 | Pubmed ID: 31733178 Selective Inhibition of Cyclooxygenase-2 Protects Porcine Aortic Endothelial Cells from Human Antibody-mediated Complement-dependent Cytotoxicity Xenotransplantation. Nov, 2019 | Pubmed ID: 31724835 Decellularization Methods for Developing Porcine Corneal Xenografts and Future Perspectives Xenotransplantation. Nov, 2019 | Pubmed ID: 31659811 Anti-Pig Antibody in Infants: Can a Genetically Engineered Pig Heart Bridge to Allotransplantation? The Annals of Thoracic Surgery. Sep, 2019 | Pubmed ID: 31580857 Human CTLA4-Ig Therapy Can Give False-positive Anti-pig Antibody Results in Primates After Xenotransplantation Transplant Immunology. 12, 2019 | Pubmed ID: 31472231 Indicators of Impending Pig Kidney and Heart Xenograft Failure: Relevance to Clinical Organ Xenotransplantation - Review Article International Journal of Surgery (London, England). Oct, 2019 | Pubmed ID: 31445094 Downregulation of Gabarapl1 Significantly Attenuates Antibody Binding to Porcine Aortic Endothelial Cells Xenotransplantation. Nov, 2019 | Pubmed ID: 31433094 Is the Renal Subcapsular Space the Preferred Site for Clinical Porcine Islet Xenotransplantation? Review Article International Journal of Surgery (London, England). Jul, 2019 | Pubmed ID: 31369877 TNF-α Promotes Human Antibody-mediated Complement-dependent Cytotoxicity of Porcine Endothelial Cells Through Downregulating P38-mediated Occludin Expression Cell Communication and Signaling : CCS. Jul, 2019 | Pubmed ID: 31307477 LIFE-SUPPORTING KIDNEY XENOTRANSPLANTATION FROM GENETICALLY-ENGINEERED PIGS IN BABOONS: A COMPARISON OF TWO IMMUNOSUPPRESSIVE REGIMENS Transplantation. Jun, 2019 | Pubmed ID: 31283686 Evidence for the Important Role of Inflammation in Xenotransplantation Journal of Inflammation (London, England). 2019 | Pubmed ID: 31148951 A Potential Role of TLR2 in Xenograft Rejection of Porcine Iliac Endothelial Cells: An in Vitro Study Xenotransplantation. May, 2019 | Pubmed ID: 31127671 Circulating Pig-specific DNA As a Novel Biomarker for Monitoring Xenograft Rejection Xenotransplantation. May, 2019 | Pubmed ID: 31077480 The Complex Functioning of the Complement System in Xenotransplantation Xenotransplantation. Apr, 2019 | Pubmed ID: 31033064 Justification of Specific Genetic Modifications in Pigs for Clinical Organ Xenotransplantation Xenotransplantation. Apr, 2019 | Pubmed ID: 30989742 The "Baby Fae" Baboon Heart Transplant-Potential Cause of Rejection Xenotransplantation. Apr, 2019 | Pubmed ID: 30932224 Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ Xenotransplantation Comparative Medicine. Apr, 2019 | Pubmed ID: 30909988 In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic Degeneration The Annals of Thoracic Surgery. Aug, 2019 | Pubmed ID: 30836101 Potential Pathological Role of Pro-inflammatory Cytokines (IL-6, TNF-α, and IL-17) in Xenotransplantation Xenotransplantation. 05, 2019 | Pubmed ID: 30770591 Carbohydrate Antigen Expression and Anti-pig Antibodies in New World Capuchin Monkeys: Relevance to Studies of Xenotransplantation Xenotransplantation. 05, 2019 | Pubmed ID: 30770572 A Review of Pig Liver Xenotransplantation: Current Problems and Recent Progress Xenotransplantation. 05, 2019 | Pubmed ID: 30767272 Genetically-engineered Pigs As Sources for Clinical Red Blood Cell Transfusion: What Pathobiological Barriers Need to Be Overcome? Blood Reviews. 05, 2019 | Pubmed ID: 30711308 Life-supporting Porcine Cardiac Xenotransplantation: The Munich Study Xenotransplantation. 05, 2019 | Pubmed ID: 30657207 Financial Support for Xenotransplantation Research Xenotransplantation. 05, 2019 | Pubmed ID: 30605230 Episodes of Hypovolemia/dehydration in Baboons with Pig Kidney Transplants: A New Syndrome of Clinical Importance? Xenotransplantation. 03, 2019 | Pubmed ID: 30485551 Experimental Pig Heart Xenotransplantation-Recent Progress and Remaining Problems The Annals of Thoracic Surgery. Apr, 2019 | Pubmed ID: 30471272 Chronic Dialysis in Patients with End-stage Renal Disease: Relevance to Kidney Xenotransplantation Xenotransplantation. 03, 2019 | Pubmed ID: 30456901 Will Donor-derived Neoplasia Be Problematic After Clinical Pig Organ or Cell Xenotransplantation? Xenotransplantation. 03, 2019 | Pubmed ID: 30411396 The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome? Pediatric Cardiology. Feb, 2019 | Pubmed ID: 30302505 Serum Amyloid a As an Indicator of Impending Xenograft Failure: Experimental Studies International Journal of Surgery (London, England). Dec, 2018 | Pubmed ID: 30521954 Data on B Cell Phenotypes in Baboons with Pig Artery Patch Grafts Receiving Conventional Immunosuppressive Therapy Data in Brief. Oct, 2018 | Pubmed ID: 30294651 Perspectives on the Optimal Genetically Engineered Pig in 2018 for Initial Clinical Trials of Kidney or Heart Xenotransplantation Transplantation. 12, 2018 | Pubmed ID: 30247446 Xenotransplantation Research and the 'International Journal of Surgery' International Journal of Surgery (London, England). 10, 2018 | Pubmed ID: 30237083 An Approach to Induction of Tolerance to Pig Cardiac Xenografts in Neonates Xenotransplantation. 11, 2018 | Pubmed ID: 30125392 B Cell Phenotypes in Baboons with Pig Artery Patch Grafts Receiving Conventional Immunosuppressive Therapy Transplant Immunology. 12, 2018 | Pubmed ID: 30092338 Christiaan Barnard-The Surgeon Who Dared: The Story of the First Human-to-human Heart Transplant Global Cardiology Science & Practice. Jun, 2018 | Pubmed ID: 30083541 Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenografts Archivum Immunologiae Et Therapiae Experimentalis. Jul, 2018 | Pubmed ID: 29992337 Porcine IL-6, IL-1β, and TNF-α Regulate the Expression of Pro-inflammatory-related Genes and Tissue Factor in Human Umbilical Vein Endothelial Cells Xenotransplantation. 09, 2018 | Pubmed ID: 29932258 20th Anniversary of IXA, 1998-2018 Xenotransplantation. 05, 2018 | Pubmed ID: 29913043 Corrigendum to "The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation" Journal of Immunology Research. 2018 | Pubmed ID: 29767012 Expression and Regulation Profile of Mature MicroRNA in the Pig: Relevance to Xenotransplantation BioMed Research International. 2018 | Pubmed ID: 29750148 Is Sensitization to Pig Antigens Detrimental to Subsequent Allotransplantation? Xenotransplantation. 05, 2018 | Pubmed ID: 29655276 Reducing Immunoreactivity of Porcine Bioprosthetic Heart Valves by Genetically-deleting Three Major Glycan Antigens, GGTA1/β4GalNT2/CMAH Acta Biomaterialia. 05, 2018 | Pubmed ID: 29631050 Skin Xenotransplantation: Historical Review and Clinical Potential Burns : Journal of the International Society for Burn Injuries. 11, 2018 | Pubmed ID: 29602717 Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates: Recent Progress Transplantation. 07, 2018 | Pubmed ID: 29538262 Bringing Home The Bacon: Update on The State of Kidney Xenotransplantation Blood Purification. 2018 | Pubmed ID: 29478054 The Sda and Cad Glycan Antigens and Their Glycosyltransferase, β1,4GalNAcT-II, in Xenotransplantation Xenotransplantation. 03, 2018 | Pubmed ID: 29430727 Joint FDA‐IXA Symposium, September 20, 2017 Xenotransplantation. 11, 2017 | Pubmed ID: 29193342 Life's Defining Moment: Christiaan Barnard and the First Human Heart Transplant The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 12, 2017 | Pubmed ID: 29173384 The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation Journal of Immunology Research. 2017 | Pubmed ID: 29159187 Low Anti-pig Antibody Levels Are Key to the Success of Solid Organ Xenotransplantation: But is This Sufficient? Xenotransplantation. 11, 2017 | Pubmed ID: 29067714 Xenotransplantation: Past, Present, and Future Current Opinion in Organ Transplantation. Dec, 2017 | Pubmed ID: 28901971 Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model Scientific Reports. 08, 2017 | Pubmed ID: 28855711 Financial Aspects of Organ Procurement from Deceased Donors in the USA-Relevance to Xenotransplantation Xenotransplantation. 07, 2017 | Pubmed ID: 28741700 Regulation of Clinical Xenotransplantation-Time for a Reappraisal Transplantation. 08, 2017 | Pubmed ID: 28737658 Altered Expression of ENOS, Prostacyclin Synthase, Prostaglandin G/H Synthase, and Thromboxane Synthase in Porcine Aortic Endothelial Cells After Exposure to Human Serum-relevance to Xenotransplantation Cell Biology International. Jul, 2017 | Pubmed ID: 28462511 Early Clinical Xenotransplantation Experiences-An Interview with Thomas E. Starzl, MD, PhD Xenotransplantation. 03, 2017 | Pubmed ID: 28421681 Thomas E. Starzl, MD, PhD, 1926-2017 Xenotransplantation. 03, 2017 | Pubmed ID: 28421680 Human IL-6, IL-17, IL-1β, and TNF-α Differently Regulate the Expression of Pro-inflammatory Related Genes, Tissue Factor, and Swine Leukocyte Antigen Class I in Porcine Aortic Endothelial Cells Xenotransplantation. 03, 2017 | Pubmed ID: 28303603 Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future Cell Transplantation. 06, 2017 | Pubmed ID: 28155815 Klotho Attenuated Antibody-mediated Porcine Endothelial Cell Activation and Injury Xenotransplantation. 01, 2017 | Pubmed ID: 28130792 Production of α1,3-galactosyltransferase and Cytidine Monophosphate-N-acetylneuraminic Acid Hydroxylase Gene Double-deficient Pigs by CRISPR/Cas9 and Handmade Cloning The Journal of Reproduction and Development. Feb, 2017 | Pubmed ID: 27725344 Inguinal Subkutan hvit fettvev (ISWAT) Transplantasjon Modell av Murine Holmer Yuanzheng Peng*1, Zhicheng Zou*1, Jiao Chen1, Hancheng Zhang1, Ying Lu1, Rito Bittino2, Hongxing Fu3, David K. C. Cooper4, Shan Lin1, Mengtao Cao1, Yifan Dai5, Zhiming Cai1, Lisha Mou1 1Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Institute of Translational Medicine, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Health Science Center, 2Institute for Cellular Therapeutics, Allegheny-Singer Research Institute, 3School of Pharmaceutical Sciences, Wenzhou Medical University, 4Xenotransplantation Program/Department of Surgery, University of Alabama at Birmingham, 5Jiangsu Key Laboratory of Xenotransplantation, Nanjing Medical University JoVE 60679 Médecine
Inguinal Subkutan hvit fettvev (ISWAT) Transplantasjon Modell av Murine Holmer Yuanzheng Peng*1, Zhicheng Zou*1, Jiao Chen1, Hancheng Zhang1, Ying Lu1, Rito Bittino2, Hongxing Fu3, David K. C. Cooper4, Shan Lin1, Mengtao Cao1, Yifan Dai5, Zhiming Cai1, Lisha Mou1 1Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Institute of Translational Medicine, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Health Science Center, 2Institute for Cellular Therapeutics, Allegheny-Singer Research Institute, 3School of Pharmaceutical Sciences, Wenzhou Medical University, 4Xenotransplantation Program/Department of Surgery, University of Alabama at Birmingham, 5Jiangsu Key Laboratory of Xenotransplantation, Nanjing Medical University JoVE 60679 Médecine