Dawn E. Bowles Division of Surgical Sciences, Department of Surgery Duke University Biography Publications Institution JoVE Articles Dawn E. Bowles has not added a biography. If you are Dawn E. Bowles and would like to personalize this page please email our Author Liaison for assistance. Publications Fortilin Inhibits P53, Halts Cardiomyocyte Apoptosis, and Protects the Heart Against Heart Failure Cell Death Discovery. Oct, 2021 | Pubmed ID: 34689154 Consequences of Space Radiation on the Brain and Cardiovascular System Journal of Environmental Science and Health. Part C, Toxicology and Carcinogenesis. 2021 | Pubmed ID: 33902387 Evolution of Bacteria in the Human Gut in Response to Changing Environments: An Invisible Player in the Game of Health Computational and Structural Biotechnology Journal. 2021 | Pubmed ID: 33552447 The Use of an Inexpensive Processing Aid Device (the Mouse PAD) to Facilitate Rodent Tissue Banking BioTechniques. 07, 2020 | Pubmed ID: 32418443 A Normothermic Ex Vivo Organ Perfusion Delivery Method for Cardiac Transplantation Gene Therapy Scientific Reports. 05, 2019 | Pubmed ID: 31142753 A Mole Rat's Gut Microbiota Suggests Selective Influence of Diet on Microbial Niche Space and Evolution Experimental Biology and Medicine (Maywood, N.J.). 04, 2019 | Pubmed ID: 30760029 NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase Antioxidants & Redox Signaling. 07, 2019 | Pubmed ID: 30450923 The Nuclear Receptor RORα Protects Against Angiotensin II-induced Cardiac Hypertrophy and Heart Failure American Journal of Physiology. Heart and Circulatory Physiology. 01, 2019 | Pubmed ID: 30387679 S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence Molecular Cell. May, 2018 | Pubmed ID: 29727618 Mdm2 Regulates Cardiac Contractility by Inhibiting GRK2-mediated Desensitization of β-adrenergic Receptor Signaling JCI Insight. Sep, 2017 | Pubmed ID: 28878120 Hypoxia Decreases Creatine Uptake in Cardiomyocytes, While Creatine Supplementation Enhances HIF Activation Physiological Reports. Aug, 2017 | Pubmed ID: 28821596 Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support ASAIO Journal (American Society for Artificial Internal Organs : 1992). Sep/Oct, 2017 | Pubmed ID: 28319523 Microgravity Induces Proteomics Changes Involved in Endoplasmic Reticulum Stress and Mitochondrial Protection Scientific Reports. Sep, 2016 | Pubmed ID: 27670941 Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support Journal of the American College of Cardiology. Jan, 2016 | Pubmed ID: 26796394 Elevated Cardiac Troponin I in Preservation Solution Is Associated With Primary Graft Dysfunction Journal of Cardiac Failure. Feb, 2016 | Pubmed ID: 26365053 Chronic Loss of Noradrenergic Tone Produces β-arrestin2-mediated Cocaine Hypersensitivity and Alters Cellular D2 Responses in the Nucleus Accumbens Addiction Biology. Jan, 2016 | Pubmed ID: 25123018 RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into C-kit(+) Cardiac Progenitor Cells Stem Cells and Development. Nov, 2015 | Pubmed ID: 26176491 Effects of Left Ventricular Assist Device Support on Biomarkers of Cardiovascular Stress, Fibrosis, Fluid Homeostasis, Inflammation, and Renal Injury JACC. Heart Failure. Jan, 2015 | Pubmed ID: 25447345 Phosphoproteomic Profiling of Human Myocardial Tissues Distinguishes Ischemic from Non-ischemic End Stage Heart Failure PloS One. 2014 | Pubmed ID: 25117565 Proteomic Analysis of the NOS2 Interactome in Human Airway Epithelial Cells Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2013 | Pubmed ID: 23438482 Gene Therapy for the Prevention of Vein Graft Disease Translational Research : the Journal of Laboratory and Clinical Medicine. Apr, 2013 | Pubmed ID: 23274305 Adeno-associated Viral Vectors Based on Serotype 3b Use Components of the Fibroblast Growth Factor Receptor Signaling Complex for Efficient Transduction Human Gene Therapy. Oct, 2012 | Pubmed ID: 22680698 Single Amino Acid Modification of Adeno-associated Virus Capsid Changes Transduction and Humoral Immune Profiles Journal of Virology. Aug, 2012 | Pubmed ID: 22593151 X-Linked Inhibitor of Apoptosis Protein-Mediated Attenuation of Apoptosis, Using a Novel Cardiac-Enhanced Adeno-Associated Viral Vector Human Gene Therapy. Mar, 2012 | Pubmed ID: 22339372 Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2012 | Pubmed ID: 22068425 Oxygen-coupled Redox Regulation of the Skeletal Muscle Ryanodine Receptor-Ca2+ Release Channel by NADPH Oxidase 4 Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21896730 AMPK and Substrate Availability Regulate Creatine Transport in Cultured Cardiomyocytes American Journal of Physiology. Endocrinology and Metabolism. May, 2011 | Pubmed ID: 21364119 Reproducibility of Left Atrial Ablation with High-intensity Focused Ultrasound Energy in a Calf Model The Journal of Thoracic and Cardiovascular Surgery. Dec, 2010 | Pubmed ID: 20934725 Osteopontin and Protein Kinase C Regulate PDLIM2 Activation and STAT1 Ubiquitination in LPS-treated Murine Macrophages The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20889505 Short-lived Alpha-helical Intermediates in the Folding of Beta-sheet Proteins Biochemistry. Jul, 2010 | Pubmed ID: 20515035 Adaptation in a Mouse Colony Monoassociated with Escherichia Coli K-12 for More Than 1,000 Days Applied and Environmental Microbiology. Jul, 2010 | Pubmed ID: 20472724 Utility of Telomerase-pot1 Fusion Protein in Vascular Tissue Engineering Cell Transplantation. 2010 | Pubmed ID: 19878625 Adeno-associated Virus Vectors: Potential Applications for Cancer Gene Therapy Cancer Gene Therapy. Dec, 2005 | Pubmed ID: 15962012 Cross-dressing the Virion: the Transcapsidation of Adeno-associated Virus Serotypes Functionally Defines Subgroups Journal of Virology. May, 2004 | Pubmed ID: 15078923 Marker Rescue of Adeno-associated Virus (AAV) Capsid Mutants: a Novel Approach for Chimeric AAV Production Journal of Virology. Jan, 2003 | Pubmed ID: 12477847 A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft Michelle Mendiola Pla1, Amy Evans2, Franklin H. Lee3, Yuting Chiang1, Muath Bishawi1, Andrew Vekstein1, Lillian Kang1, Diego Zapata4, Ryan Gross3, Alexis Carnes2, Lynden E. Gault5, Julie A. Balko6, Desiree Bonadonna2, Sam Ho5, Paul Lezberg7, Benjamin S. Bryner1, Jacob N. Schroder1, Carmelo A. Milano1, Dawn E. Bowles3 1Division of Cardiothoracic Surgery, Department of Surgery, Duke University, 2Perfusion Services, Duke University, 3Division of Surgical Sciences, Department of Surgery, Duke University, 4Division of Laboratory Animal Resources, Duke University, 5Gift of Hope Organ and Tissue Donor Network, 6College of Veterinary Medicine, North Carolina State University, 7TransMedics, Inc JoVE 63114 Médecine Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart Muath Bishawi1, Jun-Neng Roan1,2, Jordan Richards1, Zachary Brown1, Laura Blue1, Mani A. Daneshmand1, Jacob N. Schroder1, Dawn E. Bowles3, Carmelo A. Milano1 1Division of Cardiothoracic Surgery, Department of Surgery, Duke University, 2Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital and College of Medicine, 3Division of Surgical Sciences, Department of Surgery, Duke University JoVE 55961 Médecine An Isolated Working Heart System for Large Animal Models Matthew A. Schechter1, Kevin W. Southerland1, Bryan J. Feger1, Dean Linder Jr.1, Ayyaz A. Ali2, Linda Njoroge1, Carmelo A. Milano1, Dawn E. Bowles1 1Department of Surgery, Duke University Medical Center, 2Department of Cardiothoracic Surgery, University Hospital of South Manchester JoVE 51671 Médecine
A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft Michelle Mendiola Pla1, Amy Evans2, Franklin H. Lee3, Yuting Chiang1, Muath Bishawi1, Andrew Vekstein1, Lillian Kang1, Diego Zapata4, Ryan Gross3, Alexis Carnes2, Lynden E. Gault5, Julie A. Balko6, Desiree Bonadonna2, Sam Ho5, Paul Lezberg7, Benjamin S. Bryner1, Jacob N. Schroder1, Carmelo A. Milano1, Dawn E. Bowles3 1Division of Cardiothoracic Surgery, Department of Surgery, Duke University, 2Perfusion Services, Duke University, 3Division of Surgical Sciences, Department of Surgery, Duke University, 4Division of Laboratory Animal Resources, Duke University, 5Gift of Hope Organ and Tissue Donor Network, 6College of Veterinary Medicine, North Carolina State University, 7TransMedics, Inc JoVE 63114 Médecine
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart Muath Bishawi1, Jun-Neng Roan1,2, Jordan Richards1, Zachary Brown1, Laura Blue1, Mani A. Daneshmand1, Jacob N. Schroder1, Dawn E. Bowles3, Carmelo A. Milano1 1Division of Cardiothoracic Surgery, Department of Surgery, Duke University, 2Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital and College of Medicine, 3Division of Surgical Sciences, Department of Surgery, Duke University JoVE 55961 Médecine
An Isolated Working Heart System for Large Animal Models Matthew A. Schechter1, Kevin W. Southerland1, Bryan J. Feger1, Dean Linder Jr.1, Ayyaz A. Ali2, Linda Njoroge1, Carmelo A. Milano1, Dawn E. Bowles1 1Department of Surgery, Duke University Medical Center, 2Department of Cardiothoracic Surgery, University Hospital of South Manchester JoVE 51671 Médecine