Derek van der Kooy Molecular Genetics University of Toronto Biography Publications Institution JoVE Articles Derek van der Kooy has not added a biography. If you are Derek van der Kooy and would like to personalize this page please email our Author Liaison for assistance. Publications Phasic D1 and Tonic D2 Dopamine Receptor Signaling Double Dissociate the Motivational Effects of Acute Nicotine and Chronic Nicotine Withdrawal Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22308372 The Adult Mouse Dentate Gyrus Contains Populations of Committed Progenitor Cells That Are Distinct from Subependymal Zone Neural Stem Cells Stem Cells (Dayton, Ohio). Sep, 2011 | Pubmed ID: 21774038 Fetal Alcohol Exposure Leads to Abnormal Olfactory Bulb Development and Impaired Odor Discrimination in Adult Mice Molecular Brain. 2011 | Pubmed ID: 21736737 Subretinal Gene Delivery Using Helper-dependent Adenoviral Vectors Cell & Bioscience. 2011 | Pubmed ID: 21711866 β-Cell Evolution: How the Pancreas Borrowed from the Brain: The Shared Toolbox of Genes Expressed by Neural and Pancreatic Endocrine Cells May Reflect Their Evolutionary Relationship BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Aug, 2011 | Pubmed ID: 21681773 Generation of Neural Stem Cells from Embryonic Stem Cells Using the Default Mechanism: in Vitro and in Vivo Characterization Stem Cells and Development. Nov, 2011 | Pubmed ID: 21604925 Neural Stem Cells Are Increased After Loss of β-catenin, but Neural Progenitors Undergo Cell Death The European Journal of Neuroscience. Apr, 2011 | Pubmed ID: 21375603 The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells That Express Insulin Cell Stem Cell. Mar, 2011 | Pubmed ID: 21362568 Genetic Deletion of Regulator of G-protein Signaling 4 (RGS4) Rescues a Subset of Fragile X Related Phenotypes in the FMR1 Knockout Mouse Molecular and Cellular Neurosciences. Mar, 2011 | Pubmed ID: 21215802 Biology and Therapeutic Potential of Adult Retinal Stem Cells Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. Aug, 2010 | Pubmed ID: 20648091 Adenosine A1 and A2A Receptors Are Not Upstream of Caffeine's Dopamine D2 Receptor-dependent Aversive Effects and Dopamine-independent Rewarding Effects The European Journal of Neuroscience. Jul, 2010 | Pubmed ID: 20576036 Insulin Signaling Plays a Dual Role in Caenorhabditis Elegans Memory Acquisition and Memory Retrieval The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010 | Pubmed ID: 20534848 A Diacetyl-induced Quiescence in Young Caenorhabditis Elegans Behavioural Brain Research. Dec, 2010 | Pubmed ID: 20493908 A Hydrogel-based Stem Cell Delivery System to Treat Retinal Degenerative Diseases Biomaterials. Mar, 2010 | Pubmed ID: 20056272 Dopaminergic Signaling Mediates the Motivational Response Underlying the Opponent Process to Chronic but Not Acute Nicotine Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Mar, 2010 | Pubmed ID: 20032966 Maximizing Functional Photoreceptor Differentiation from Adult Human Retinal Stem Cells Stem Cells (Dayton, Ohio). Mar, 2010 | Pubmed ID: 20014120 Stem Cells in 2009 Cell Stem Cell. Nov, 2009 | Pubmed ID: 19896440 Regulation of Vertebrate Nervous System Alternative Splicing and Development by an SR-related Protein Cell. Sep, 2009 | Pubmed ID: 19737518 A Safer Stem Cell: Inducing Pluripotency Nature Medicine. Sep, 2009 | Pubmed ID: 19734874 Low Oxygen Enhances Primitive and Definitive Neural Stem Cell Colony Formation by Inhibiting Distinct Cell Death Pathways Stem Cells (Dayton, Ohio). Aug, 2009 | Pubmed ID: 19544448 Ventral Tegmental Area BDNF Induces an Opiate-dependent-like Reward State in Naive Rats Science (New York, N.Y.). Jun, 2009 | Pubmed ID: 19478142 Different Neural Systems Mediate Morphine Reward and Its Spontaneous Withdrawal Aversion The European Journal of Neuroscience. May, 2009 | Pubmed ID: 19453632 The Germline Stem Cells of Drosophila Melanogaster Partition DNA Non-randomly European Journal of Cell Biology. Jul, 2009 | Pubmed ID: 19395121 E-Cadherin Regulates Neural Stem Cell Self-renewal The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2009 | Pubmed ID: 19321785 GABA(A) Receptors Mediate the Opposing Roles of Dopamine and the Tegmental Pedunculopontine Nucleus in the Motivational Effects of Ethanol The European Journal of Neuroscience. Mar, 2009 | Pubmed ID: 19302158 Suppression of Oct4 by Germ Cell Nuclear Factor Restricts Pluripotency and Promotes Neural Stem Cell Development in the Early Neural Lineage The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2009 | Pubmed ID: 19228964 Tegmental Pedunculopontine Glutamate and GABA-B Synapses Mediate Morphine Reward Behavioral Neuroscience. Feb, 2009 | Pubmed ID: 19170439 Global Survey of Genomic Imprinting by Transcriptome Sequencing Current Biology : CB. Nov, 2008 | Pubmed ID: 19026546 Serotonin Mediates a Learned Increase in Attraction to High Concentrations of Benzaldehyde in Aged C. Elegans Learning & Memory (Cold Spring Harbor, N.Y.). Nov, 2008 | Pubmed ID: 18984566 Don't Look: Growing Clonal Versus Nonclonal Neural Stem Cell Colonies Stem Cells (Dayton, Ohio). Nov, 2008 | Pubmed ID: 18757294 Neurologic Phenotype of Schimke Immuno-osseous Dysplasia and Neurodevelopmental Expression of SMARCAL1 Journal of Neuropathology and Experimental Neurology. Jun, 2008 | Pubmed ID: 18520775 Cortex- and Striatum- Derived Neural Stem Cells Produce Distinct Progeny in the Olfactory Bulb and Striatum The European Journal of Neuroscience. May, 2008 | Pubmed ID: 18445225 A Test of the Opponent-process Theory of Motivation Using Lesions That Selectively Block Morphine Reward The European Journal of Neuroscience. Jun, 2007 | Pubmed ID: 17610590 Ciliary Margin Transdifferentiation from Neural Retina is Controlled by Canonical Wnt Signaling Developmental Biology. Aug, 2007 | Pubmed ID: 17574231 Functional Coordination of Alternative Splicing in the Mammalian Central Nervous System Genome Biology. 2007 | Pubmed ID: 17565696 Adhesion is Prerequisite, but Alone Insufficient, to Elicit Stem Cell Pluripotency The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17507566 The Proliferation and Expansion of Retinal Stem Cells Require Functional Pax6 Developmental Biology. Apr, 2007 | Pubmed ID: 17316600 A Progressive and Cell Non-autonomous Increase in Striatal Neural Stem Cells in the Huntington's Disease R6/2 Mouse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2006 | Pubmed ID: 17035529 Embryonic Cortical Neural Stem Cells Migrate Ventrally and Persist As Postnatal Striatal Stem Cells The Journal of Cell Biology. Oct, 2006 | Pubmed ID: 17030986 Vascular Endothelial Growth Factor Directly Inhibits Primitive Neural Stem Cell Survival but Promotes Definitive Neural Stem Cell Survival The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16793887 Notch Signaling is Required to Maintain All Neural Stem Cell Populations--irrespective of Spatial or Temporal Niche Developmental Neuroscience. 2006 | Pubmed ID: 16508302 Loss of Retinal Progenitor Cells Leads to an Increase in the Retinal Stem Cell Population in Vivo The European Journal of Neuroscience. Jan, 2006 | Pubmed ID: 16420417 Embryonic Stem Cells Assume a Primitive Neural Stem Cell Fate in the Absence of Extrinsic Influences The Journal of Cell Biology. Jan, 2006 | Pubmed ID: 16390999 Developing Human-nonhuman Chimeras in Human Stem Cell Research: Ethical Issues and Boundaries Kennedy Institute of Ethics Journal. Jun, 2005 | Pubmed ID: 16149204 Support for the Immortal Strand Hypothesis: Neural Stem Cells Partition DNA Asymmetrically in Vitro The Journal of Cell Biology. Aug, 2005 | Pubmed ID: 16115957 Dopamine Specifically Inhibits Forebrain Neural Stem Cell Proliferation, Suggesting a Novel Effect of Antipsychotic Drugs The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15958748 P21 Loss Compromises the Relative Quiescence of Forebrain Stem Cell Proliferation Leading to Exhaustion of Their Proliferation Capacity Genes & Development. Mar, 2005 | Pubmed ID: 15769947 Intrinsic Differences Distinguish Transiently Neurogenic Progenitors from Neural Stem Cells in the Early Postnatal Brain Developmental Biology. Feb, 2005 | Pubmed ID: 15649462 A Genetic Dissociation of Learning and Recall in Caenorhabditis Elegans Behavioral Neuroscience. Dec, 2004 | Pubmed ID: 15598130 The Functional Landscape of Mouse Gene Expression Journal of Biology. 2004 | Pubmed ID: 15588312 Facile Isolation and the Characterization of Human Retinal Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Nov, 2004 | Pubmed ID: 15505221 GABAA Receptors Signal Bidirectional Reward Transmission from the Ventral Tegmental Area to the Tegmental Pedunculopontine Nucleus As a Function of Opiate State The European Journal of Neuroscience. Oct, 2004 | Pubmed ID: 15450097 Clonal Identification of Multipotent Precursors from Adult Mouse Pancreas That Generate Neural and Pancreatic Lineages Nature Biotechnology. Sep, 2004 | Pubmed ID: 15322557 Primitive Neural Stem Cells from the Mammalian Epiblast Differentiate to Definitive Neural Stem Cells Under the Control of Notch Signaling Genes & Development. Aug, 2004 | Pubmed ID: 15289455 Contextual Taste Cues Modulate Olfactory Learning in C. Elegans by an Occasion-setting Mechanism Current Biology : CB. Jul, 2004 | Pubmed ID: 15268863 DREAM Ablation Selectively Alters THC Place Aversion and Analgesia but Leaves Intact the Motivational and Analgesic Effects of Morphine The European Journal of Neuroscience. Jun, 2004 | Pubmed ID: 15182311 It is Ethical to Transplant Human Stem Cells into Nonhuman Embryos Nature Medicine. Apr, 2004 | Pubmed ID: 15057220 Disguising Adult Neural Stem Cells Current Opinion in Neurobiology. Feb, 2004 | Pubmed ID: 15018948 Dopamine Modulates the Plasticity of Mechanosensory Responses in Caenorhabditis Elegans The EMBO Journal. Jan, 2004 | Pubmed ID: 14739932 Opiate State Controls Bi-directional Reward Signaling Via GABAA Receptors in the Ventral Tegmental Area Nature Neuroscience. Feb, 2004 | Pubmed ID: 14730310 The Neurobiology of Nicotine Addiction: Bridging the Gap from Molecules to Behaviour Nature Reviews. Neuroscience. Jan, 2004 | Pubmed ID: 14708004 Excitotoxic Lesions of the Tegmental Pedunculopontine Nucleus Impair Copulation in Naive Male Rats and Block the Rewarding Effects of Copulation in Experienced Male Rats The European Journal of Neuroscience. Nov, 2003 | Pubmed ID: 14622159 The Ablation of Glial Fibrillary Acidic Protein-positive Cells from the Adult Central Nervous System Results in the Loss of Forebrain Neural Stem Cells but Not Retinal Stem Cells The European Journal of Neuroscience. Jul, 2003 | Pubmed ID: 12859339 Stem and Progenitor Cells: the Premature Desertion of Rigorous Definitions Trends in Neurosciences. Mar, 2003 | Pubmed ID: 12591214 The Motivational Valence of Nicotine in the Rat Ventral Tegmental Area is Switched from Rewarding to Aversive Following Blockade of the Alpha7-subunit-containing Nicotinic Acetylcholine Receptor Psychopharmacology. Mar, 2003 | Pubmed ID: 12569428 In Vivo Infusions of Exogenous Growth Factors into the Fourth Ventricle of the Adult Mouse Brain Increase the Proliferation of Neural Progenitors Around the Fourth Ventricle and the Central Canal of the Spinal Cord The European Journal of Neuroscience. Sep, 2002 | Pubmed ID: 12383233 Lesions of the Tegmental Pedunculopontine Nucleus Block the Rewarding Effects and Reveal the Aversive Effects of Nicotine in the Ventral Tegmental Area The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002 | Pubmed ID: 12351739 Serotonin Mediates Food-odor Associative Learning in the Nematode Caenorhabditiselegans Proceedings of the National Academy of Sciences of the United States of America. Sep, 2002 | Pubmed ID: 12202746 Notch Pathway Molecules Are Essential for the Maintenance, but Not the Generation, of Mammalian Neural Stem Cells Genes & Development. Apr, 2002 | Pubmed ID: 11937492 Adult Rodent Neurogenic Regions: the Ventricular Subependyma Contains Neural Stem Cells, but the Dentate Gyrus Contains Restricted Progenitors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2002 | Pubmed ID: 11880507 Hematopoietic Competence is a Rare Property of Neural Stem Cells That May Depend on Genetic and Epigenetic Alterations Nature Medicine. Mar, 2002 | Pubmed ID: 11875498 Motivational State Determines the Functional Role of the Mesolimbic Dopamine System in the Mediation of Opiate Reward Processes Behavioural Brain Research. Feb, 2002 | Pubmed ID: 11809491 DREAM is a Critical Transcriptional Repressor for Pain Modulation Cell. Jan, 2002 | Pubmed ID: 11792319 Neural Stem Cell Lineages Are Regionally Specified, but Not Committed, Within Distinct Compartments of the Developing Brain Development (Cambridge, England). Jan, 2002 | Pubmed ID: 11782416 Выделение стволовых клеток сетчатки от мыши глаз Brenda L.K. Coles1, Derek van der Kooy1 1Molecular Genetics, University of Toronto JoVE 2209 Biologie
Выделение стволовых клеток сетчатки от мыши глаз Brenda L.K. Coles1, Derek van der Kooy1 1Molecular Genetics, University of Toronto JoVE 2209 Biologie