Ernst Klar Department of General, Thoracic, Vascular and Transplantation Surgery Rostock University Medical Center Biography Publications Institution JoVE Articles Ernst Klar has not added a biography. If you are Ernst Klar and would like to personalize this page please email our Author Liaison for assistance. Publications Endoscopic Vacuum Therapy for Various Defects of the Upper Gastrointestinal Tract Surgical Endoscopy. Jan, 2017 | Pubmed ID: 28078463 Extending the Limits of Resection for Colorectal Liver Metastases Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Jan, 2017 | Pubmed ID: 27619805 Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models BioMed Research International. 2016 | Pubmed ID: 27999790 The Effects of Hydrogen Sulfide on Platelet-leukocyte Aggregation and Microvascular Thrombolysis Platelets. Nov, 2016 | Pubmed ID: 27819526 Open Surgical Versus Minimal Invasive Necrosectomy of the Pancreas-A Retrospective Multicenter Analysis of the German Pancreatitis Study Group PloS One. 2016 | Pubmed ID: 27668746 The Mutational Profile and Infiltration Pattern of Murine MLH1-/- Tumors: Concurrences, Disparities and Cell Line Establishment for Functional Analysis Oncotarget. Aug, 2016 | Pubmed ID: 27447752 Differential Effects of Endogenous, Phyto and Synthetic Cannabinoids on Thrombogenesis and Platelet Activity BioFactors (Oxford, England). Nov, 2016 | Pubmed ID: 27151562 Establishment and Characterization of HROC69 - a Crohn´s Related Colonic Carcinoma Cell Line and Its Matched Patient-derived Xenograft Scientific Reports. Apr, 2016 | Pubmed ID: 27087592 Surgical Endoscopic Vacuum Therapy for Defects of the Upper Gastrointestinal Tract Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Feb, 2016 | Pubmed ID: 26643296 Endoscopic Vacuum Therapy in Colorectal Surgery Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Feb, 2016 | Pubmed ID: 26597270 Ectopic Spleen Tissue - an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour Viszeralmedizin. Dec, 2015 | Pubmed ID: 26889148 Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype PloS One. 2015 | Pubmed ID: 26618628 Surgical Principles in the Treatment of Ulcerative Colitis Viszeralmedizin. Aug, 2015 | Pubmed ID: 26557832 Inflammatory Bowel Diseases: Current Medical and Surgical Therapy Viszeralmedizin. Aug, 2015 | Pubmed ID: 26557829 Optimizing the Process of Nucleofection for Professional Antigen Presenting Cells BMC Research Notes. Sep, 2015 | Pubmed ID: 26404473 Graft Rinse Prior to Reperfusion in Liver Transplantation: Literature Review and Online Survey Within the Eurotransplant Community Transplant International : Official Journal of the European Society for Organ Transplantation. Nov, 2015 | Pubmed ID: 26147505 Reactivity Against Microsatellite Instability-induced Frameshift Mutations in Patients with Inflammatory Bowel Disease World Journal of Gastroenterology. Jan, 2015 | Pubmed ID: 25574094 Establishment and Characterization of Cell Lines from Chromosomal Instable Colorectal Cancer World Journal of Gastroenterology. Jan, 2015 | Pubmed ID: 25574089 Endoscopic Continuity-preserving Therapy for Esophageal Stenosis and Perforation Following Colliquative Necrosis Endoscopy. 2014 | Pubmed ID: 25254576 VEGF-releasing Suture Material for Enhancement of Vascularization: Development, in Vitro and in Vivo Study Acta Biomaterialia. Dec, 2014 | Pubmed ID: 25204522 Gastric Gastrointestinal Stromal Tumor Lost in the Peritoneum After Endoscopic Resection Endoscopy. 2014 | Pubmed ID: 25121627 Host Defense Peptides for Treatment of Colorectal Carcinoma - a Comparative in Vitro and in Vivo Analysis Oncotarget. Jun, 2014 | Pubmed ID: 24962950 Future Perspectives for Surgical Research in Germany Langenbeck's Archives of Surgery. Mar, 2014 | Pubmed ID: 24615143 Intensified Neoadjuvant Radiochemotherapy for Rectal Cancer Enhances Surgical Complications BMC Surgery. Sep, 2013 | Pubmed ID: 24073705 Acute Cholecystitis: Early Versus Delayed Cholecystectomy, a Multicenter Randomized Trial (ACDC Study, NCT00447304) Annals of Surgery. Sep, 2013 | Pubmed ID: 24022431 Prognosis of Rectal Cancer Patients Improves with Downstaging by Intensified Neoadjuvant Radiochemotherapy - a Matched Pair Analysis BMC Cancer. Aug, 2013 | Pubmed ID: 23947828 Scoring of Human Acute Pancreatitis: State of the Art Langenbeck's Archives of Surgery. Aug, 2013 | Pubmed ID: 23680979 Is the Lymph Node Ratio Superior to the Union for International Cancer Control (UICC) TNM System in Prognosis of Colon Cancer? World Journal of Surgical Oncology. Mar, 2013 | Pubmed ID: 23521843 Reperfusion of Liver Graft During Transplantation: Techniques Used in Transplant Centres Within Eurotransplant and Meta-analysis of the Literature Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2013 | Pubmed ID: 23517278 The "North German Tumor Bank of Colorectal Cancer": Status Report After the First 2 years of Support by the German Cancer Aid Foundation Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Feb, 2013 | Pubmed ID: 23292500 R1 Resection in Pancreatic Cancer Has Significant Impact on Long-term Outcome in Standardized Pathology Modified for Routine Use Surgery. Sep, 2012 | Pubmed ID: 22766366 Volume-outcome Relationship in Pancreatic Surgery: the Situation in Germany Surgery. Sep, 2012 | Pubmed ID: 22763260 A Novel Sialyl Le(X) Expression Score As a Potential Prognostic Tool in Colorectal Cancer World Journal of Surgical Oncology. 2012 | Pubmed ID: 22621806 Acute Mesenteric Ischemia: a Vascular Emergency Deutsches Arzteblatt International. Apr, 2012 | Pubmed ID: 22536301 Ex-vivo Clonally Expanded B Lymphocytes Infiltrating Colorectal Carcinoma Are of Mature Immunophenotype and Produce Functional IgG PloS One. 2012 | Pubmed ID: 22393427 Treatment of Necrotizing Pancreatitis: Redefining the Role of Surgery World Journal of Surgery. May, 2012 | Pubmed ID: 22382765 Combining Bacterial-immunotherapy with Therapeutic Antibodies: a Novel Therapeutic Concept Vaccine. Apr, 2012 | Pubmed ID: 22342917 Bacterial Immunotherapy of Gastrointestinal Tumors Langenbeck's Archives of Surgery. Apr, 2012 | Pubmed ID: 22189906 Immunosuppressants Accelerate Microvascular Thrombus Formation in Vivo: Role of Endothelial Cell Activation Surgery. Jan, 2012 | Pubmed ID: 22019501 Multidrug Strategies Are Effective in the Treatment of Severe Experimental Pancreatitis Surgery. Mar, 2012 | Pubmed ID: 21982067 Multidrug-resistance Proteins Are Weak Tumor Associated Antigens for Colorectal Carcinoma BMC Immunology. Jul, 2011 | Pubmed ID: 21740599 DTG Procurement Guidelines in Heart Beating Donors Transplant International : Official Journal of the European Society for Organ Transplantation. Jul, 2011 | Pubmed ID: 21668528 Impact of Portal Branch Ligation on Tissue Regeneration, Microcirculatory Response and Microarchitecture in Portal Blood-deprived and Undeprived Liver Tissue Microvascular Research. May, 2011 | Pubmed ID: 21397614 Extracorporeal Cell Therapy of Septic Shock Patients with Donor Granulocytes: a Pilot Study Critical Care (London, England). 2011 | Pubmed ID: 21371308 Pharmacokinetics and Penetration of Moxifloxacin into Infected Diabetic Foot Tissue in a Large Diabetic Patient Cohort European Journal of Clinical Pharmacology. Feb, 2011 | Pubmed ID: 20871984 Laparoscopic Treatment of Renal Artery Entrapment Journal of Vascular Surgery. Nov, 2010 | Pubmed ID: 20678884 Bacteriolytic Therapy of Experimental Pancreatic Carcinoma World Journal of Gastroenterology. Jul, 2010 | Pubmed ID: 20653063 Cryopreservation of Human Colorectal Carcinomas Prior to Xenografting BMC Cancer. Jul, 2010 | Pubmed ID: 20615215 Induction of HSP70 Shows Differences in Protection Against I/R Injury Derived by Ischemic Preconditioning and Intermittent Clamping Microvascular Research. Dec, 2010 | Pubmed ID: 20478315 Identification of an MSI-H Tumor-specific Cytotoxic T Cell Epitope Generated by the (-1) Frame of U79260(FTO) Journal of Biomedicine & Biotechnology. 2010 | Pubmed ID: 20339516 Generation of Highly Pure Fusions of Colorectal Carcinoma and Antigen-presenting Cells Langenbeck's Archives of Surgery. Apr, 2010 | Pubmed ID: 20309577 Microvascular Dysfunction in Hepatic Ischemia-reperfusion Injury in Pigs Microvascular Research. Jul, 2010 | Pubmed ID: 20184903 Postoperative Care Following Pancreatic Surgery: Surveillance and Treatment Deutsches Arzteblatt International. Nov, 2009 | Pubmed ID: 20038981 Quantification of Liver Perfusion by Dynamic Magnetic Resonance Imaging: Experimental Evaluation and Clinical Pilot Study Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jul, 2009 | Pubmed ID: 19562702 Primary Human Hepatocytes Are Protected Against Complement by Multiple Regulators Molecular Immunology. Jul, 2009 | Pubmed ID: 19446335 Intensified Irinotecan-based Neoadjuvant Chemoradiotherapy in Rectal Cancer: Four Consecutive Designed Studies to Minimize Acute Toxicity and to Optimize Efficacy Measured by Pathologic Complete Response Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Dec, 2007 | Pubmed ID: 18036687 基于 Poly(L-lactide) 和 Poly(4-hydroxybutyrate) 为周边血管的应用程序的可生物降解的支架: 猪的初步经验。 Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists. Oct, 2007 | Pubmed ID: 17924740 Induction of an Antitumoral Immune Response by Wild-type Adeno-associated Virus Type 2 in an in Vivo Model of Pancreatic Carcinoma Pancreas. Jul, 2007 | Pubmed ID: 17575547 Effect of Neoadjuvant Chemoradiation on Postoperative Fecal Continence and Anal Sphincter Function in Rectal Cancer Patients International Journal of Colorectal Disease. Nov, 2007 | Pubmed ID: 17497160 Effect of Parathyroidectomy on Quality of Life and Neuropsychological Symptoms in Primary Hyperparathyroidism World Journal of Surgery. Jun, 2007 | Pubmed ID: 17460812 Distinct Effects of Acute and Chronic Nicotine Application on Microvascular Thrombus Formation and Endothelial Function in Male and Female Mice Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. May, 2007 | Pubmed ID: 17384961 Darbepoetin-alpha Does Not Promote Microvascular Thrombus Formation in Mice: Role of ENOS-dependent Protection Through Platelet and Endothelial Cell Deactivation Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2007 | Pubmed ID: 17347485 雷帕霉素洗脱生物降解材料聚-L-丙交酯支架周围血管应用: 猪颈动脉的初步研究。 The Journal of Surgical Research. May, 2007 | Pubmed ID: 17292417 Systemic Hypothermia Increases PAI-1 Expression and Accelerates Microvascular Thrombus Formation in Endotoxemic Mice Critical Care (London, England). 2006 | Pubmed ID: 17062126 Dynamic Changes of Post-ischemic Hepatic Microcirculation Improved by a Pre-treatment of Phosphodiesterase-3 Inhibitor, Milrinone The Journal of Surgical Research. Dec, 2006 | Pubmed ID: 17045613 髂吻合口支架置入术雷帕霉素洗脱的生物降解材料聚-L-丙交酯支架: 6 周后的初步研究。 Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists. Oct, 2006 | Pubmed ID: 17042669 Effective Antitumoral Immune Responses Are Not Induced by Cytosine Deaminase Suicide Gene Transfer in a Syngeneic Rat Pancreatic Carcinoma Model European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes. 2006 | Pubmed ID: 17028434 Penetration of Moxifloxacin into the Human Pancreas Following a Single Intravenous or Oral Dose The Journal of Antimicrobial Chemotherapy. Nov, 2006 | Pubmed ID: 16956903 Iliac Anastomotic Stenting with a Biodegradable Poly-L-lactide Stent: a Preliminary Study After 1 and 6 Weeks Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists. Aug, 2006 | Pubmed ID: 16928171 Postoperative Chemotherapy May Not Be Necessary for Patients with YpN0-category After Neoadjuvant Chemoradiotherapy of Rectal Cancer Diseases of the Colon and Rectum. Sep, 2006 | Pubmed ID: 16758130 Activating Anti-CD40 Antibodies Induce Tumour Invasion by Cytotoxic T-lymphocytes and Inhibition of Tumour Growth in Experimental Liver Cancer European Journal of Cancer (Oxford, England : 1990). May, 2006 | Pubmed ID: 16564167 Ciclosporin Aggravates Tissue Damage in Ischemia Reperfusion-induced Acute Pancreatitis Pancreas. Mar, 2006 | Pubmed ID: 16552333 Hepatic Platelet and Leukocyte Adherence During Endotoxemia Critical Care (London, England). Feb, 2006 | Pubmed ID: 16420661 HEGPOL: Randomized, Placebo Controlled, Multicenter, Double-blind Clinical Trial to Investigate Hepatoprotective Effects of Glycine in the Postoperative Phase of Liver Transplantation [ISRCTN69350312] BMC Surgery. Aug, 2005 | Pubmed ID: 16105183 Axillary-axillary Interarterial Chest Loop Conduit As an Alternative for Chronic Hemodialysis Access Journal of Vascular Surgery. Aug, 2005 | Pubmed ID: 16102629 Sustained Hypothermia Accelerates Microvascular Thrombus Formation in Mice American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2005 | Pubmed ID: 16100248 Identification of Differentially Expressed Genes After Partial Rat Liver Ischemia/reperfusion by Suppression Subtractive Hybridization World Journal of Gastroenterology. Mar, 2005 | Pubmed ID: 15761968 Control of T-cell-mediated Immune Response by HLA Class I in Human Pancreatic Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2005 | Pubmed ID: 15701833 Neoadjuvant Radiochemotherapy in Locally Advanced Gastric Carcinoma Strahlentherapie Und Onkologie : Organ Der Deutschen Rontgengesellschaft ... [et Al]. Nov, 2004 | Pubmed ID: 15549187 The Effect of Adenovirus Expressing Wild-type P53 on 5-fluorouracil Chemosensitivity is Related to P53 Status in Pancreatic Cancer Cell Lines World Journal of Gastroenterology. Dec, 2004 | Pubmed ID: 15534911 Expansion of Endothelial Surface by an Increase of Vessel Diameter During Tumor Angiogenesis in Experimental and Hepatocellular and Pancreatic Cancer World Journal of Gastroenterology. Nov, 2004 | Pubmed ID: 15457566 C1-inhibitor Reduces Hepatic Leukocyte-endothelial Interaction and the Expression of VCAM-1 in LPS-induced Sepsis in the Rat Microvascular Research. Mar, 2004 | Pubmed ID: 15020209 Effects of Heparin in Experimental Models of Acute Pancreatitis and Post-ERCP Pancreatitis Surgery. Feb, 2004 | Pubmed ID: 14739847 Detection and Prognostic Relevance of Cytokeratin 20 in Differentiated and Anaplastic Thyroid Carcinomas by RT-PCR Surgery. Dec, 2003 | Pubmed ID: 14668729 Donor Pretreatment with Gadolinium Chloride Improves Early Graft Function and Survival After Porcine Liver Transplantation Transplant International : Official Journal of the European Society for Organ Transplantation. Nov, 2003 | Pubmed ID: 12879229 Primary Human Hepatocytes--a Valuable Tool for Investigation of Apoptosis and Hepatitis B Virus Infection Journal of Hepatology. Jun, 2003 | Pubmed ID: 12763365 Oxygen Radicals Promote ICAM-1 Expression and Microcirculatory Disturbances in Experimental Acute Pancreatitis Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]. 2003 | Pubmed ID: 12748425 Assessment of Renal Graft Function by Perioperative Monitoring of Cortical Microcirculation in Kidney Transplantation Transplantation. Apr, 2003 | Pubmed ID: 12717202 Radiation-induced Leukocyte Adhesion to Endothelium in Normal Pancreas and in Pancreatic Carcinoma of the Rat International Journal of Cancer. Jul, 2003 | Pubmed ID: 12712442 Different Radiogenic Effects on Microcirculation in Healthy Pancreas and in Pancreatic Carcinoma of the Rat Annals of Surgery. Apr, 2003 | Pubmed ID: 12677148 Detection of Hematogenic and Lymphogenic Tumor Cell Dissemination in Patients with Medullary Thyroid Carcinoma by Cytokeratin 20 and Preprogastrin-releasing Peptide RT-PCR International Journal of Cancer. Jan, 2003 | Pubmed ID: 12455065 RET Proto-oncogene Mutations Affecting Codon 790/791: A Mild Form of Multiple Endocrine Neoplasia Type 2A Syndrome? Surgery. Dec, 2002 | Pubmed ID: 12490841 Limits of Couinaud's Liver Segment Classification: a Quantitative Computer-based Three-dimensional Analysis Journal of Computer Assisted Tomography. Nov-Dec, 2002 | Pubmed ID: 12488744 原发性结直肠癌和其肺内转移: 临床、 桑叶、 免疫和凝集素、 组织化学、 核和句法结构分析重点的转移和生存期间发生关联。 APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jun, 2002 | Pubmed ID: 12193204 Pancreatic Capillary Blood Flow in an Improved Model of Necrotizing Pancreatitis in the Rat The Journal of Surgical Research. Aug, 2002 | Pubmed ID: 12175989 Ischemic Preconditioning by Brief Extremity Ischemia Before Flap Ischemia in a Rat Model Plastic and Reconstructive Surgery. Jun, 2002 | Pubmed ID: 12045567 Reduction in Mortality with Delayed Surgical Therapy of Severe Pancreatitis Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. May-Jun, 2002 | Pubmed ID: 12023003 Combination of T-cell Therapy and Trigger of Inflammation Induces Remodeling of the Vasculature and Tumor Eradication Cancer Research. Mar, 2002 | Pubmed ID: 11888921 Detection of Disseminated Medullary Thyroid Carcinoma Cells in Cervical Lymph Nodes by Cytokeratin 20 Reverse Transcription-polymerase Chain Reaction World Journal of Surgery. Feb, 2002 | Pubmed ID: 11865340 Immunoprophylaxis with Basiliximab, a Chimeric Anti-interleukin-2 Receptor Monoclonal Antibody, in Combination with Azathioprine-containing Triple Therapy in Liver Transplant Recipients Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Feb, 2002 | Pubmed ID: 11862588 Transformation of the Microvascular System During Multistage Tumorigenesis International Journal of Cancer. Feb, 2002 | Pubmed ID: 11857345 活体显微镜及血栓诱导在无毛小鼠的耳垂 Daniel Strüder*1, Eberhard Grambow*2, Ernst Klar2, Robert Mlynski1, Brigitte Vollmar3 1Department of Otorhinolaryngology, Head and Neck Surgery "Otto Koerner", Rostock University Medical Center, 2Department of General, Thoracic, Vascular and Transplantation Surgery, Rostock University Medical Center, 3Institute for Experimental Surgery, Rostock University Medical Center JoVE 55174 Médecine
活体显微镜及血栓诱导在无毛小鼠的耳垂 Daniel Strüder*1, Eberhard Grambow*2, Ernst Klar2, Robert Mlynski1, Brigitte Vollmar3 1Department of Otorhinolaryngology, Head and Neck Surgery "Otto Koerner", Rostock University Medical Center, 2Department of General, Thoracic, Vascular and Transplantation Surgery, Rostock University Medical Center, 3Institute for Experimental Surgery, Rostock University Medical Center JoVE 55174 Médecine