Frank Edenhofer Institute of Anatomy and Cell Biology University of Würzburg Biography Publications Institution JoVE Articles Frank Edenhofer has not added a biography. If you are Frank Edenhofer and would like to personalize this page please email our Author Liaison for assistance. Publications Quantification of Cell Fusion Events Human Breast Cancer Cells and Breast Epithelial Cells Using a Cre-LoxP-based Double Fluorescence Reporter System Cellular and Molecular Life Sciences : CMLS. Apr, 2015 | Pubmed ID: 25900663 Robust Generation of Cardiomyocytes from Human IPS Cells Requires Precise Modulation of BMP and WNT Signaling Stem Cell Reviews. Aug, 2015 | Pubmed ID: 25392050 Characterization of a Novel Cell Penetrating Peptide Derived from Human Oct4 Cell Regeneration (London, England). 2014 | Pubmed ID: 25408881 Excision of Viral Reprogramming Cassettes by Cre Protein Transduction Enables Rapid, Robust and Efficient Derivation of Transgene-free Human Induced Pluripotent Stem Cells Stem Cell Research & Therapy. 2014 | Pubmed ID: 24713299 Cell-permeant Recombinant Nanog Protein Promotes Pluripotency by Inhibiting Endodermal Specification Stem Cell Research. May, 2014 | Pubmed ID: 24681518 A LewisX Glycoprotein Screen Identifies the Low Density Lipoprotein Receptor-related Protein 1 (LRP1) As a Modulator of Oligodendrogenesis in Mice The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23615909 A Thermoresponsive and Chemically Defined Hydrogel for Long-term Culture of Human Embryonic Stem Cells Nature Communications. 2013 | Pubmed ID: 23299885 Automated Selection and Harvesting of Pluripotent Stem Cell Colonies Biotechnology and Applied Biochemistry. Mar-Apr, 2012 | Pubmed ID: 23586788 MicroRNAs Are Indispensable for Reprogramming Mouse Embryonic Fibroblasts into Induced Stem Cell-like Cells PloS One. 2012 | Pubmed ID: 22737231 Cellular Reprogramming Employing Recombinant Sox2 Protein Stem Cells International. 2012 | Pubmed ID: 22693519 Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells Cell Stem Cell. Apr, 2012 | Pubmed ID: 22445518 Non-Genetic Modulation of Notch Activity by Artificial Delivery of Notch Intracellular Domain into Neural Stem Cells Stem Cell Reviews. Jan, 2012 | Pubmed ID: 22290418 Genetic Engineering of Mammalian Cells by Direct Delivery of FLP Recombinase Protein Methods (San Diego, Calif.). Apr, 2011 | Pubmed ID: 21185381 Exploring Refined Conditions for Reprogramming Cells by Recombinant Oct4 Protein The International Journal of Developmental Biology. 2010 | Pubmed ID: 21404191 Sox2 is Essential for Formation of Trophectoderm in the Preimplantation Embryo PloS One. 2010 | Pubmed ID: 21103067 Peroxisome Proliferator-activated Receptor (PPAR)gamma Can Inhibit Chronic Renal Allograft Damage The American Journal of Pathology. May, 2010 | Pubmed ID: 20363918 Transcription Factor-based Modulation of Neural Stem Cell Differentiation Using Direct Protein Transduction Cellular and Molecular Life Sciences : CMLS. Jul, 2010 | Pubmed ID: 20352468 Engineering Cell-permeant FLP Recombinase for Tightly Controlled Inducible and Reversible Overexpression in Embryonic Stem Cells Stem Cells (Dayton, Ohio). May, 2010 | Pubmed ID: 20333748 Inhibition of Notch Signaling in Human Embryonic Stem Cell-derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation in Vitro and in Vivo Stem Cells (Dayton, Ohio). May, 2010 | Pubmed ID: 20235098 Monodispersity of Recombinant Cre Recombinase Correlates with Its Effectiveness in Vivo BMC Biotechnology. 2009 | Pubmed ID: 19747375 Dre Recombinase, Like Cre, is a Highly Efficient Site-specific Recombinase in E. Coli, Mammalian Cells and Mice Disease Models & Mechanisms. Sep-Oct, 2009 | Pubmed ID: 19692579 Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-beta in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009 | Pubmed ID: 19667093 Deciphering the Stem Cell Machinery As a Basis for Understanding the Molecular Mechanism Underlying Reprogramming Cellular and Molecular Life Sciences : CMLS. Nov, 2009 | Pubmed ID: 19662495 Increased Antigen Cross-presentation but Impaired Cross-priming After Activation of Peroxisome Proliferator-activated Receptor Gamma is Mediated by Up-regulation of B7H1 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19535643 Protein Transduction Revisited: Novel Insights into the Mechanism Underlying Intracellular Delivery of Proteins Current Pharmaceutical Design. 2008 | Pubmed ID: 19075739 Generation of Transducible Versions of Transcription Factors Oct4 and Sox2 Biological Chemistry. Jul, 2008 | Pubmed ID: 18681826 Runx Genes Are Direct Targets of Scl/Tal1 in the Yolk Sac and Fetal Liver Blood. Mar, 2008 | Pubmed ID: 18184866 Stem Cell Engineering Using Transducible Cre Recombinase Methods in Molecular Medicine. 2007 | Pubmed ID: 18085201 Enhanced Purification of Cell-permeant Cre and Germline Transmission After Transduction into Mouse Embryonic Stem Cells Genesis (New York, N.Y. : 2000). Aug, 2007 | Pubmed ID: 17661398 Peroxisome Proliferator-activated Receptor Gamma Control of Dendritic Cell Function Contributes to Development of CD4+ T Cell Anergy Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007 | Pubmed ID: 17277116 Stage-specific Conditional Mutagenesis in Mouse Embryonic Stem Cell-derived Neural Cells and Postmitotic Neurons by Direct Delivery of Biologically Active Cre Recombinase Stem Cells (Dayton, Ohio). Jan, 2007 | Pubmed ID: 16960133 Cargo-dependent Mode of Uptake and Bioavailability of TAT-containing Proteins and Peptides in Living Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2006 | Pubmed ID: 16940149 Merging Fields: Stem Cells in Neurogenesis, Transplantation, and Disease Modeling Brain Pathology (Zurich, Switzerland). Apr, 2006 | Pubmed ID: 16768756 Site-specific Recombination in Human Embryonic Stem Cells Induced by Cell-permeant Cre Recombinase Nature Methods. Jun, 2006 | Pubmed ID: 16721380 MTOR is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells Molecular and Cellular Biology. Aug, 2004 | Pubmed ID: 15254238 Efficient in Vitro and in Vivo Excision of Floxed Sequences with a High-capacity Adenoviral Vector Expressing Cre Recombinase Genesis (New York, N.Y. : 2000). Jul, 2002 | Pubmed ID: 12124944 Ability of the Hydrophobic FGF and Basic TAT Peptides to Promote Cellular Uptake of Recombinant Cre Recombinase: a Tool for Efficient Genetic Engineering of Mammalian Genomes Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002 | Pubmed ID: 11904364 Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells Sandra Meyer1,2, Philipp Wörsdörfer1, Katharina Günther1, Marc Thier2,3, Frank Edenhofer1,2 1Institute of Anatomy and Cell Biology, University of Würzburg, 2Institute of Reconstructive Neurobiology, University of Bonn, 3German Cancer Research Center, Heidelberg JoVE 52831 Neurosciences Engineering Cell-permeable Protein Bernhard Münst1, Christoph Patsch1, Frank Edenhofer1 1Stem Cell Engineering Group, Institute of Reconstructive Neurobiology, University of Bonn - Life & Brain Center and Hertie Foundation JoVE 1627 Biologie
Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells Sandra Meyer1,2, Philipp Wörsdörfer1, Katharina Günther1, Marc Thier2,3, Frank Edenhofer1,2 1Institute of Anatomy and Cell Biology, University of Würzburg, 2Institute of Reconstructive Neurobiology, University of Bonn, 3German Cancer Research Center, Heidelberg JoVE 52831 Neurosciences
Engineering Cell-permeable Protein Bernhard Münst1, Christoph Patsch1, Frank Edenhofer1 1Stem Cell Engineering Group, Institute of Reconstructive Neurobiology, University of Bonn - Life & Brain Center and Hertie Foundation JoVE 1627 Biologie