George A. O'Toole Department of Microbiology & Immunology Geisel School of Medicine at Dartmouth Biography Publications Institution JoVE Articles George A. O'Toole has not added a biography. If you are George A. O'Toole and would like to personalize this page please email our Author Liaison for assistance. Publications The Gut-Lung Axis in Cystic Fibrosis Journal of Bacteriology. Aug, 2021 | Pubmed ID: 34339302 Biochemical and Structural Characterization of Two Cif-like Epoxide Hydrolases from Current Research in Structural Biology. 2021 | Pubmed ID: 34235487 Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability Microbiology Spectrum. Jul, 2021 | Pubmed ID: 34232099 Interaction Between the Type 4 Pili Machinery and a Diguanylate Cyclase Fine-tune C-di-GMP Levels During Early Biofilm Formation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2021 | Pubmed ID: 34168081 One Versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway MBio. 03, 2021 | Pubmed ID: 33727344 Characterization of Ciprofloxacin Resistance Levels: Implications for Ototopical Therapy Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 08, 2021 | Pubmed ID: 33710149 Metabolic Modeling to Interrogate Microbial Disease: A Tale for Experimentalists Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 33681294 Uses C-di-GMP Phosphodiesterases RmcA and MorA To Regulate Biofilm Maintenance MBio. 02, 2021 | Pubmed ID: 33531388 Roadmap on Emerging Concepts in the Physical Biology of Bacterial Biofilms: from Surface Sensing to Community Formation Physical Biology. Jun, 2021 | Pubmed ID: 33462162 Identification of Cell-surface Glycans That Mediate Motility-dependent Binding and Internalization of Pseudomonas Aeruginosa by Phagocytes Molecular Immunology. 03, 2021 | Pubmed ID: 33358569 Aerosolized Drug-loaded Nanoparticles Targeting Migration Inhibitory Factors Inhibit -induced Inflammation and Biofilm Formation Nanomedicine (London, England). 12, 2020 | Pubmed ID: 33241979 Discovering the Molecular Determinants of Phaeobacter Inhibens Susceptibility to Phaeobacter Phage MD18 MSphere. 11, 2020 | Pubmed ID: 33148823 From Input to Output: The Lap/c-di-GMP Biofilm Regulatory Circuit Annual Review of Microbiology. 09, 2020 | Pubmed ID: 32689917 Pseudomonas Aeruginosa PA14 Enhances the Efficacy of Norfloxacin Against Staphylococcus Aureus Newman Biofilms Journal of Bacteriology. 08, 2020 | Pubmed ID: 32661077 MapA, a Second Large RTX Adhesin Conserved Across the Pseudomonads, Contributes to Biofilm Formation by Pseudomonas Fluorescens Journal of Bacteriology. 08, 2020 | Pubmed ID: 32631946 Age and Environmental Exposures Influence the Fecal Bacteriome of Young Children with Cystic Fibrosis Pediatric Pulmonology. 07, 2020 | Pubmed ID: 32275127 Lung Function and Microbiota Diversity in Cystic Fibrosis Microbiome. 04, 2020 | Pubmed ID: 32238195 Social Cooperativity of Bacteria During Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas Aeruginosa PA14 and PAO1 MBio. 02, 2020 | Pubmed ID: 32098815 Exogenous Alginate Protects Staphylococcus Aureus from Killing by Pseudomonas Aeruginosa Journal of Bacteriology. Mar, 2020 | Pubmed ID: 31792010 Availability of Zinc Impacts Interactions Between Streptococcus Sanguinis and Pseudomonas Aeruginosa in Coculture Journal of Bacteriology. 01, 2020 | Pubmed ID: 31685535 Gross Transcriptomic Analysis of Pseudomonas Putida for Diagnosing Environmental Shifts Microbial Biotechnology. 01, 2020 | Pubmed ID: 30957409 Interspecies Interactions Induce Exploratory Motility in ELife. 11, 2019 | Pubmed ID: 31713513 Lying in Wait: Modeling the Control of Bacterial Infections Via Antibiotic-Induced Proviruses MSystems. Oct, 2019 | Pubmed ID: 31575664 "It Takes a Village": Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms Journal of Bacteriology. 12, 2019 | Pubmed ID: 31548277 Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Biofilms Journal of Medicinal Chemistry. 09, 2019 | Pubmed ID: 31449405 Special Meeting Issue for the 8th ASM Conference on Biofilms Journal of Bacteriology. 09, 2019 | Pubmed ID: 31439756 Pseudomonas Aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus Aureus to Membrane-Targeting Antiseptics and Antibiotics MBio. 07, 2019 | Pubmed ID: 31363032 Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth Journal of Bacteriology. 08, 2019 | Pubmed ID: 31209076 Bordetella Bronchiseptica Diguanylate Cyclase BdcA Regulates Motility and Is Important for the Establishment of Respiratory Infection in Mice Journal of Bacteriology. 09, 2019 | Pubmed ID: 31209073 Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance MSystems. Mar-Apr, 2019 | Pubmed ID: 31020043 The Yin and Yang of Lung Infections in Cystic Fibrosis: a Model for Studying Polymicrobial Interactions Journal of Bacteriology. 06, 2019 | Pubmed ID: 30885933 Pseudomonas Aeruginosa Can Inhibit Growth of Streptococcal Species Via Siderophore Production Journal of Bacteriology. 04, 2019 | Pubmed ID: 30718303 Flagellar Stators Stimulate C-di-GMP Production by Pseudomonas Aeruginosa Journal of Bacteriology. 09, 2019 | Pubmed ID: 30642992 Co-opting the Lap System of Pseudomonas Fluorescens To Reversibly Customize Bacterial Cell Surfaces ACS Synthetic Biology. 11, 2018 | Pubmed ID: 30278125 Ligand-Mediated Biofilm Formation Via Enhanced Physical Interaction Between a Diguanylate Cyclase and Its Receptor MBio. 07, 2018 | Pubmed ID: 29991582 Special Sections for the 6th ASM Conference on Cell-Cell Communication in Bacteria Journal of Bacteriology. 07, 2018 | Pubmed ID: 29941545 Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate Journal of Bacteriology. 09, 2018 | Pubmed ID: 29866808 Multigenerational Memory and Adaptive Adhesion in Early Bacterial Biofilm Communities Proceedings of the National Academy of Sciences of the United States of America. 04, 2018 | Pubmed ID: 29559526 An N-Terminal Retention Module Anchors the Giant Adhesin LapA of Pseudomonas Fluorescens at the Cell Surface: a Novel Subfamily of Type I Secretion Systems Journal of Bacteriology. 04, 2018 | Pubmed ID: 29437852 A Multimodal Strategy Used by a Large C-di-GMP Network Journal of Bacteriology. 04, 2018 | Pubmed ID: 29311282 Cystic Fibrosis Airway Microbiome: Overturning the Old, Opening the Way for the New Journal of Bacteriology. 02, 2018 | Pubmed ID: 29084859 Special Meeting Sections for the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition Journal of Bacteriology. 11, 2017 | Pubmed ID: 29042432 An Antipersister Strategy for Treatment of Chronic Pseudomonas Aeruginosa Infections Antimicrobial Agents and Chemotherapy. Dec, 2017 | Pubmed ID: 28923873 High-Speed "4D" Computational Microscopy of Bacterial Surface Motility ACS Nano. 09, 2017 | Pubmed ID: 28836761 Alters Staphylococcus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection MBio. 07, 2017 | Pubmed ID: 28720732 Special Meeting Sections for the 6th ASM Conference on Beneficial Microbes Journal of Bacteriology. 08, 2017 | Pubmed ID: 28698224 A Symphony of Cyclases: Specificity in Diguanylate Cyclase Signaling Annual Review of Microbiology. 09, 2017 | Pubmed ID: 28645224 Classic Spotlights: Selected Highlights from the First 100 Years of the Journal of Bacteriology. 07, 2017 | Pubmed ID: 28611240 Pseudomonas Aeruginosa-Derived Rhamnolipids and Other Detergents Modulate Colony Morphotype and Motility in the Burkholderia Cepacia Complex Journal of Bacteriology. 07, 2017 | Pubmed ID: 28439038 Alginate Overproduction Promotes Coexistence with in a Model of Cystic Fibrosis Respiratory Infection MBio. 03, 2017 | Pubmed ID: 28325763 Bacteria, Rev Your Engines: Stator Dynamics Regulate Flagellar Motility Journal of Bacteriology. 06, 2017 | Pubmed ID: 28320878 Role of Cyclic Di-GMP and Exopolysaccharide in Type IV Pilus Dynamics Journal of Bacteriology. 04, 2017 | Pubmed ID: 28167523 Special Meeting Sections Journal of Bacteriology. 01, 2016 | Pubmed ID: 28588069 Classic Spotlight: How the Gram Stain Works Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815540 Classic Spotlight: Plate Counting You Can Count On Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815539 Classic Spotlight: Bacteroides Thetaiotaomicron, Starch Utilization, and the Birth of the Microbiome Era Journal of Bacteriology. 10, 2016 | Pubmed ID: 27660335 Special Meeting Sections for the 7th ASM Conference on Biofilms Journal of Bacteriology. 10, 2016 | Pubmed ID: 27613861 Requirements for Pseudomonas Aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay Journal of Bacteriology. 11, 2016 | Pubmed ID: 27573013 Cyanide Toxicity to Burkholderia Cenocepacia Is Modulated by Polymicrobial Communities and Environmental Factors Frontiers in Microbiology. 2016 | Pubmed ID: 27242743 Classic Spotlight: Cyclic Di-GMP, the Molecule That Makes the Bacterial World Stop Going 'Round Journal of Bacteriology. 06, 2016 | Pubmed ID: 27179064 PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas Aeruginosa Journal of Bacteriology. 07, 2016 | Pubmed ID: 27114465 The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein Journal of Bacteriology. 06, 2016 | Pubmed ID: 27002135 Sensational Biofilms: Surface Sensing in Bacteria Current Opinion in Microbiology. Apr, 2016 | Pubmed ID: 26968016 Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems Journal of Bacteriology. 05, 2016 | Pubmed ID: 26929301 Species-dependent Hydrodynamics of Flagellum-tethered Bacteria in Early Biofilm Development Journal of the Royal Society, Interface. Feb, 2016 | Pubmed ID: 26864892 Classic Spotlight: Quorum Sensing and the Multicellular Life of Unicellular Organisms Journal of Bacteriology. Feb, 2016 | Pubmed ID: 26825965 Classic Spotlight: Before They Were Biofilms Journal of Bacteriology. 01, 2016 | Pubmed ID: 26668270 Tobramycin-Treated Pseudomonas Aeruginosa PA14 Enhances Streptococcus Constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System Journal of Bacteriology. 01, 2016 | Pubmed ID: 26483523 Cyclic Di-GMP-Regulated Periplasmic Proteolysis of a Pseudomonas Aeruginosa Type Vb Secretion System Substrate Journal of Bacteriology. 01, 2016 | Pubmed ID: 26100041 Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat PLoS Pathogens. Dec, 2015 | Pubmed ID: 26719892 Iron-dependent Gene Expression in Actinomyces Oris Journal of Oral Microbiology. 2015 | Pubmed ID: 26685151 Contribution of Physical Interactions to Signaling Specificity Between a Diguanylate Cyclase and Its Effector MBio. Dec, 2015 | Pubmed ID: 26670387 Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas Aeruginosa in a Cystic Fibrosis Model System of Biofilm Formation PloS One. 2015 | Pubmed ID: 26506004 C-di-GMP and Its Effects on Biofilm Formation and Dispersion: a Pseudomonas Aeruginosa Review Microbiology Spectrum. Apr, 2015 | Pubmed ID: 26104694 Haemophilus Influenzae Responds to Glucocorticoids Used in Asthma Therapy by Modulation of Biofilm Formation and Antibiotic Resistance EMBO Molecular Medicine. Aug, 2015 | Pubmed ID: 25995336 Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas Aeruginosa Mediated by Increased Expression of Phage-Related Genes MBio. May, 2015 | Pubmed ID: 25968642 Coculture of Staphylococcus Aureus with Pseudomonas Aeruginosa Drives S. Aureus Towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model Journal of Bacteriology. Jul, 2015 | Pubmed ID: 25917910 Associations Between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis The Journal of Pediatrics. Jul, 2015 | Pubmed ID: 25818499 A Hierarchical Cascade of Second Messengers Regulates Pseudomonas Aeruginosa Surface Behaviors MBio. Jan, 2015 | Pubmed ID: 25626906 Characterization and Quantification of the Fungal Microbiome in Serial Samples from Individuals with Cystic Fibrosis Microbiome. 2014 | Pubmed ID: 25408892 Surface Attachment Induces Pseudomonas Aeruginosa Virulence Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25385640 Candida Albicans Ethanol Stimulates Pseudomonas Aeruginosa WspR-controlled Biofilm Formation As Part of a Cyclic Relationship Involving Phenazines PLoS Pathogens. Oct, 2014 | Pubmed ID: 25340349 Mechanistic Insight into the Conserved Allosteric Regulation of Periplasmic Proteolysis by the Signaling Molecule Cyclic-di-GMP ELife. Sep, 2014 | Pubmed ID: 25182848 Epoxide-mediated Differential Packaging of Cif and Other Virulence Factors into Outer Membrane Vesicles Journal of Bacteriology. Oct, 2014 | Pubmed ID: 25112474 The Microbiome in Pediatric Cystic Fibrosis Patients: the Role of Shared Environment Suggests a Window of Intervention Microbiome. 2014 | Pubmed ID: 25071935 The Microbiota Regulates Susceptibility to Fas-mediated Acute Hepatic Injury Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2014 | Pubmed ID: 25068658 Structural Features of the Pseudomonas Fluorescens Biofilm Adhesin LapA Required for LapG-dependent Cleavage, Biofilm Formation, and Cell Surface Localization Journal of Bacteriology. Aug, 2014 | Pubmed ID: 24837291 Plate-based Assay for Swarming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818898 Plate-based Assay for Swimming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818897 Micro-patterned Surfaces Reduce Bacterial Colonization and Biofilm Formation in Vitro: Potential for Enhancing Endotracheal Tube Designs Clinical and Translational Medicine. 2014 | Pubmed ID: 24739529 Deletion Mutant Library for Investigation of Functional Outputs of Cyclic Diguanylate Metabolism in Pseudomonas Aeruginosa PA14 Applied and Environmental Microbiology. Jun, 2014 | Pubmed ID: 24657857 Single-cell and Single-molecule Analysis Deciphers the Localization, Adhesion, and Mechanics of the Biofilm Adhesin LapA ACS Chemical Biology. Feb, 2014 | Pubmed ID: 24556201 Pseudomonas Aeruginosa Flagellar Motility Activates the Phagocyte PI3K/Akt Pathway to Induce Phagocytic Engulfment American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2014 | Pubmed ID: 24487390 Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24474692 Single-molecule Analysis of Pseudomonas Fluorescens Footprints ACS Nano. Feb, 2014 | Pubmed ID: 24456070 Synthesis of Bioinspired Carbohydrate Amphiphiles That Promote and Inhibit Biofilms Chemical Science (Royal Society of Chemistry : 2010). Feb, 2014 | Pubmed ID: 24376911 Iron Supplementation Does Not Worsen Respiratory Health or Alter the Sputum Microbiome in Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. May, 2014 | Pubmed ID: 24332997 Unique Microbial Communities Persist in Individual Cystic Fibrosis Patients Throughout a Clinical Exacerbation Microbiome. Nov, 2013 | Pubmed ID: 24451123 Pouring Salt on a Wound: Pseudomonas Aeruginosa Virulence Factors Alter Na+ and Cl- Flux in the Lung Journal of Bacteriology. Sep, 2013 | Pubmed ID: 23836869 Eradication of Pseudomonas Aeruginosa Biofilms on Cultured Airway Cells by a Fosfomycin/tobramycin Antibiotic Combination Pathogens and Disease. Feb, 2013 | Pubmed ID: 23620118 Cyclic-di-GMP Signalling Regulates Motility and Biofilm Formation in Bordetella Bronchiseptica Microbiology (Reading, England). May, 2013 | Pubmed ID: 23475948 Atomic Force and Super-resolution Microscopy Support a Role for LapA As a Cell-surface Biofilm Adhesin of Pseudomonas Fluorescens Research in Microbiology. Nov-Dec, 2012 | Pubmed ID: 23064158 Second Messenger Regulation of Biofilm Formation: Breakthroughs in Understanding C-di-GMP Effector Systems Annual Review of Cell and Developmental Biology. 2012 | Pubmed ID: 23057745 The CRISPR/Cas Adaptive Immune System of Pseudomonas Aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages Journal of Bacteriology. Nov, 2012 | Pubmed ID: 22885297 Iron Homeostasis During Cystic Fibrosis Pulmonary Exacerbation Clinical and Translational Science. Aug, 2012 | Pubmed ID: 22883617 Epoxide-mediated CifR Repression of Cif Gene Expression Utilizes Two Binding Sites in Pseudomonas Aeruginosa Journal of Bacteriology. Oct, 2012 | Pubmed ID: 22843844 In Vitro Evaluation of Tobramycin and Aztreonam Versus Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis-derived Human Airway Epithelial Cells The Journal of Antimicrobial Chemotherapy. Nov, 2012 | Pubmed ID: 22843834 Does the F508-CFTR Mutation Induce a Proinflammatory Response in Human Airway Epithelial Cells? American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2012 | Pubmed ID: 22821996 LapG, Required for Modulating Biofilm Formation by Pseudomonas Fluorescens Pf0-1, is a Calcium-dependent Protease Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707708 Structural Characterization of a Conserved, Calcium-dependent Periplasmic Protease from Legionella Pneumophila Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707706 広域スペクトル抗菌剤としてDiphosphoniumイオン性液体 Cornea. Jan, 2012 | Pubmed ID: 22236790 嚢胞性線維症気道で発見される細菌性のシス-2 - 不飽和脂肪酸は緑膿菌の病原性と持続性の変調 The ISME Journal. Dec, 2011 | Pubmed ID: 22134647 新興·再興感染症に対抗するために悪用するデンドリマー多価 Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 22126461 2 - ヘプチル-4 - キノロン、シュードモナスキノロンシグナル分子の前駆体は、緑膿菌(Pseudomonas Aeruginosa)に群がって運動を調節する Journal of Bacteriology. Dec, 2011 | Pubmed ID: 21965567 細菌べん毛ねじりの段階的な損失は、プログレッシブ貪食回避を付与する PLoS Pathogens. Sep, 2011 | Pubmed ID: 21949654 シュードモナスPF0-1によるバイオフィルム形成を促進Diguanylateシクラーゼの系統的解析 Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21764921 C-ジ-GMPシグナル伝達を介して個々のアミノ酸による緑膿菌(Pseudomonas Aeruginosa)の表面に関連した集団行動の変調 Research in Microbiology. Sep, 2011 | Pubmed ID: 21554951 ホストユビキチン蛋白質分解システムをハイジャック緑膿菌毒素 PLoS Pathogens. Mar, 2011 | Pubmed ID: 21455491 CSYとCAS3タンパク質を介する非アイデンティティ媒介CRISPR-バクテリオファージの相互作用 Journal of Bacteriology. Jul, 2011 | Pubmed ID: 21398535 ペリプラズムタンパク質分解を制御するシグナリングインサイドアウトC - ジ-GMP-媒介の構造的基盤 PLoS Biology. 2011 | Pubmed ID: 21304926 C-ジ-GMPエフェクターシステムはインサイドアウトシグナリングと表面タンパク質切断によって細胞接着を制御します PLoS Biology. 2011 | Pubmed ID: 21304920 細胞外多糖によって変調された緑膿菌バイオフィルムのアミノグリコシド耐性 International Microbiology : the Official Journal of the Spanish Society for Microbiology. Dec, 2010 | Pubmed ID: 21404215 2つのC-ジ-GMP Diguanylate酸シクラーゼによる緑膿菌の表面に関連した行動の特定のコントロール MBio. 2010 | Pubmed ID: 20978535 多価PEG化ペプチドのチタンコーティングで黄色ブドウ球菌の耐性 Biomaterials. Dec, 2010 | Pubmed ID: 20863561 貪食の緑膿菌(Pseudomonas Aeruginosa)の回避は、水泳運動の喪失によって媒介されると鞭毛発現の独立しています Infection and Immunity. Jul, 2010 | Pubmed ID: 20457788 抗体と免疫エフェクター:シェーピンググラム陰性細菌の表現型 Trends in Microbiology. Jun, 2010 | Pubmed ID: 20359893 緑膿菌による運動を群れの環状ジ-GMP-媒介弾圧:PilY1遺伝子と表面に関連した行動への影響 Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20233936 C-ジ-GMP依存性経路の変調のViaシュードモナスによるジアデノシン四リン(Ap4A)代謝への影響バイオフィルム形成 Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20154123 CIFは、エポキシド加水分解酵素の毒性因子の新規な活性部位の特徴を明らかに嚢胞性線維症膜コンダクタンス制御因子抑制因子の結晶構造 Journal of Bacteriology. Apr, 2010 | Pubmed ID: 20118260 糖脂肪酸エステルは、食品媒介性病原細菌によるバイオフィルム形成を阻害 International Journal of Food Microbiology. Mar, 2010 | Pubmed ID: 20089325 緑膿菌(Pseudomonas Aeruginosa)マグネシウムトランスポーターMgtEはIII型分泌システムの転写を阻害する Infection and Immunity. Mar, 2010 | Pubmed ID: 20028803 宿主由来のラクトフェリンに対する緑膿菌の鞭毛媒介バイオ防御メカニズム Infection and Immunity. Oct, 2009 | Pubmed ID: 19651866 感染性チタン金属のPEG化ペプチドコーティングの指示総会 Journal of the American Chemical Society. Aug, 2009 | Pubmed ID: 19621876 細菌の新しい酵母遺伝子改変ツール Plasmid. Sep, 2009 | Pubmed ID: 19477196 緑膿菌外膜小胞による細菌の病原性因子の長距離配達 PLoS Pathogens. Apr, 2009 | Pubmed ID: 19360133 LAPDは、ビス - (3 '、5') - 環状シュードモナスPF0-1で表面接着を調節するダイマーGMP-結合タンパク質である Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19218451 トブラマイシンとFDA承認鉄キレート剤は嚢胞性線維細胞に緑膿菌のバイオフィルムを除去する American Journal of Respiratory Cell and Molecular Biology. Sep, 2009 | Pubmed ID: 19168700 微生物バイオフィルムの発達モデル:最大レビューのためのパラダイムの10年 Trends in Microbiology. Feb, 2009 | Pubmed ID: 19162483 バクテリオファージDMS3とホストCRISPR領域との間の相互作用は、緑膿菌の集団行動を抑制する Journal of Bacteriology. Jan, 2009 | Pubmed ID: 18952788 P-糖タンパク質(MDR1)のドキソルビシンと表面発現のChemotoxicityは、緑膿菌毒素CIFによって調節されている American Journal of Physiology. Cell Physiology. Sep, 2008 | Pubmed ID: 18650266 CIFは、負TetRファミリープレッサーCifRによって調節されている Infection and Immunity. Jul, 2008 | Pubmed ID: 18458065 増加鉄の可用性ごとに、緑膿菌による増加バイオフィルム形成にDeltaF508-CFTR変異の結果 American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2008 | Pubmed ID: 18359885 フィブロネクチン結合タンパク質とGraRS 2成分制御系に依存している黄色ブドウ球菌の代替クエン酸に依存するバイオフィルム形成経路の遺伝学的証拠 Infection and Immunity. Jun, 2008 | Pubmed ID: 18347039 嚢胞性線維症気道における緑膿菌バイオフィルム形成 Pulmonary Pharmacology & Therapeutics. Aug, 2008 | Pubmed ID: 18234534 嚢胞性線維症由来気道上皮細胞におけるトブラマイシン処理緑膿菌バイオフィルムのin Vitroでの解析で Infection and Immunity. Apr, 2008 | Pubmed ID: 18212077 緑膿菌PAO1株とPA14と慢性肺感染症のラットモデルにおけるHypervirulentひずみLESB58のin Vivo増殖 Journal of Bacteriology. Apr, 2008 | Pubmed ID: 18083816 緑膿菌の鞭毛は、界面活性剤タンパク質によってクリアランスへの抵抗が必要です PloS One. 2007 | Pubmed ID: 17593964 SADCは相互に菌体外多糖生産と鞭毛機能のモジュレーション経由でバイオフィルム形成と群がって運動に影響を与える Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586642 BifA、環状ジ-GMPホスホジエステラーゼは、逆に緑膿菌PA14によるバイオフィルム形成と群がって運動を調節する Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586641 緑膿菌によるバイオフィルム形成におけるべん毛ステータの役割 Research in Microbiology. Jun, 2007 | Pubmed ID: 17533122 緑膿菌分泌タンパク質PA2934は、嚢胞性線維症膜コンダクタンス制御因子の頂端膜発現を低下させる Infection and Immunity. Aug, 2007 | Pubmed ID: 17502391 緑膿菌PA14によるバイオフィルム形成と群がっ運動の逆規制 Journal of Bacteriology. May, 2007 | Pubmed ID: 17337585 C-ジ-GMPレベルのリン酸依存性の変調アドヘシンラパの分泌を制御することにより、シュードモナスPF0-1バイオフィルム形成を調節する Molecular Microbiology. Feb, 2007 | Pubmed ID: 17302799 Micavibrio Aeruginosavorusへの病原性バイオフィルムの脆弱性 Applied and Environmental Microbiology. Jan, 2007 | Pubmed ID: 17098913 Peptide-PEG Amphiphiles As Cytophobic Coatings for Mammalian and Bacterial Cells Chemistry & Biology. Jul, 2006 | Pubmed ID: 16873017 グラム陰性菌からの遺伝子の操作のためのサッカロミセス·セレビシエ(Saccharomyces Cerevisiae)ベースの分子ツールキット Applied and Environmental Microbiology. Jul, 2006 | Pubmed ID: 16820502 カテーテルロック溶液は、非生物表面上に黄色ブドウ球菌バイオフィルム形成に影響を与える Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Aug, 2006 | Pubmed ID: 16627606 シュードモナスWCS365によるバイオフィルム形成:LAPDの役割 Microbiology (Reading, England). May, 2006 | Pubmed ID: 16622054 シュードモナスPF0-1フォーレギュロンの保全 Applied and Environmental Microbiology. Mar, 2006 | Pubmed ID: 16517638 緑膿菌(Pseudomonas Aeruginosa)は、偏ヒト気道上皮細胞におけるCFTRのエンドサイトーシスリサイクルを阻害する American Journal of Physiology. Cell Physiology. Mar, 2006 | Pubmed ID: 16236828 静的なバイオフィルムの成長と分析 Current Protocols in Microbiology. Jul, 2005 | Pubmed ID: 18770545 細菌のバイオフィルムと眼感染症 The Ocular Surface. Apr, 2005 | Pubmed ID: 17131010 バイオフィルムは反撃 Nature Biotechnology. Nov, 2005 | Pubmed ID: 16273068 緑膿菌ラムノリピッドは、気管支敗血症菌バイオフィルムを分散させる FEMS Microbiology Letters. Sep, 2005 | Pubmed ID: 16098688 ヘパリンは、黄色ブドウ球菌のバイオフィルム形成を刺激する Infection and Immunity. Aug, 2005 | Pubmed ID: 16040971 Bdellovibrio Bacteriovorus攻撃へのバイオフィルムの感受性 Applied and Environmental Microbiology. Jul, 2005 | Pubmed ID: 16000819 3成分の規制システムは、緑膿菌のバイオフィルムの成熟とタイプIII分泌を調節する Journal of Bacteriology. Feb, 2005 | Pubmed ID: 15687209 緑膿菌の運動性の2つのべん毛ステータとその役割についての証拠 Journal of Bacteriology. Jan, 2005 | Pubmed ID: 15629949 微生物学:ジキルまたは隠す? Nature. Dec, 2004 | Pubmed ID: 15592392 プロビデンシア·スチュアルティ、大腸菌の細胞外シグナル伝達分子の生産にCysEの役割:CysEの損失は、大腸菌のバイオフィルム形成を強化 Journal of Bacteriology. Nov, 2004 | Pubmed ID: 15516574 SADBは、緑膿菌PA14によるバイオフィルム形成時に添付ファイルを不可逆的なリバーシブルからの移行が必要です Journal of Bacteriology. Jul, 2004 | Pubmed ID: 15231779 緑膿菌PAO1株とPA14のための一般形質導入ファージの単離とキャラクタリゼーション Journal of Bacteriology. May, 2004 | Pubmed ID: 15126493 緑膿菌バイオフィルムの抗生物質抵抗性の遺伝的基礎 Nature. Nov, 2003 | Pubmed ID: 14628055 シュードモナスWCS365によるバイオフィルム形成の間に可逆から不可逆的な添付ファイルへの移行は、ABCトランスポーターと大分泌タンパク質が必要です Molecular Microbiology. Aug, 2003 | Pubmed ID: 12890017 アルギン酸塩は、PA14とPAO1緑膿菌バイオフィルムの細胞外多糖類マトリックスの重要なコンポーネントではありません Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12810959 バイオフィルムをビルドするには Journal of Bacteriology. May, 2003 | Pubmed ID: 12700246 ラムノリピッド界面活性剤の生産は緑膿菌PAO1におけるバイオアーキテクチャーに影響を与える Journal of Bacteriology. Feb, 2003 | Pubmed ID: 12533479 微生物学:抵抗スイッチ Nature. Apr, 2002 | Pubmed ID: 11961541 嚢胞性線維症気道マイクロバイオームに対する酸素付加の効果を研究するモデルの設計と開発 Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Médecine マイクロタイター皿のバイオフィルム形成アッセイ George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunologie et Infection
嚢胞性線維症気道マイクロバイオームに対する酸素付加の効果を研究するモデルの設計と開発 Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Médecine
マイクロタイター皿のバイオフィルム形成アッセイ George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunologie et Infection