George J. Augustine Lee Kong Chian School of Medicine Nanyang Technological University Biography Publications Institution JoVE Articles George J. Augustine has not added a biography. If you are George J. Augustine and would like to personalize this page please email our Author Liaison for assistance. Publications A Neuroprotective Role for MicroRNA MiR-1000 Mediated by Limiting Glutamate Excitotoxicity Nature Neuroscience. Feb, 2015 | Pubmed ID: 25643297 STIM2 Regulates PKA-dependent Phosphorylation and Trafficking of AMPARs Molecular Biology of the Cell. Jan, 2015 | Pubmed ID: 25609091 Protein Tyrosine Phosphatase Receptor Type R is Required for Purkinje Cell Responsiveness in Cerebellar Long-term Depression Molecular Brain. Jan, 2015 | Pubmed ID: 25571783 Presynaptic Nanodomains: a Tale of Two Synapses Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25674049 Optogenetics Reveals a Role for Accumbal Medium Spiny Neurons Expressing Dopamine D2 Receptors in Cocaine-induced Behavioral Sensitization Frontiers in Behavioral Neuroscience. 2014 | Pubmed ID: 25352792 Optogenetic Activation of Presynaptic Inputs in Lateral Amygdala Forms Associative Fear Memory Learning & Memory (Cold Spring Harbor, N.Y.). Nov, 2014 | Pubmed ID: 25322798 Optogenetic Mapping of Cerebellar Inhibitory Circuitry Reveals Spatially Biased Coordination of Interneurons Via Electrical Synapses Cell Reports. Jun, 2014 | Pubmed ID: 24857665 Optogenetic Stimulation of the Auditory Pathway The Journal of Clinical Investigation. Mar, 2014 | Pubmed ID: 24509078 Precise Control of Movement Kinematics by Optogenetic Inhibition of Purkinje Cell Activity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2014 | Pubmed ID: 24501371 Next-generation Transgenic Mice for Optogenetic Analysis of Neural Circuits Frontiers in Neural Circuits. 2013 | Pubmed ID: 24324405 Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-free Protein Engineering Automation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2013 | Pubmed ID: 24107961 In Vivo Optogenetic Tracing of Functional Corticocortical Connections Between Motor Forelimb Areas Frontiers in Neural Circuits. 2013 | Pubmed ID: 23554588 Light-emitting Channelrhodopsins for Combined Optogenetic and Chemical-genetic Control of Neurons PloS One. 2013 | Pubmed ID: 23544095 Probing the Function of Neuronal Populations: Combining Micromirror-based Optogenetic Photostimulation with Voltage-sensitive Dye Imaging Neuroscience Research. Jan, 2013 | Pubmed ID: 23254260 Optogenetically Induced Sleep Spindle Rhythms Alter Sleep Architectures in Mice Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23169668 Calcium As a Trigger for Cerebellar Long-term Synaptic Depression Cerebellum (London, England). Sep, 2012 | Pubmed ID: 21975855 Imaging Synaptic Inhibition with the Genetically Encoded Chloride Indicator Clomeleon Cold Spring Harbor Protocols. Dec, 2011 | Pubmed ID: 22135666 Cell Type–specific Channelrhodopsin-2 Transgenic Mice for Optogenetic Dissection of Neural Circuitry Function Nature Methods. Sep, 2011 | Pubmed ID: 21985008 The Diffusional Properties of Dendrites Depend on the Density of Dendritic Spines The European Journal of Neuroscience. Aug, 2011 | Pubmed ID: 21771115 Optogenetic Probing of Functional Brain Circuitry Experimental Physiology. Jan, 2011 | Pubmed ID: 21056968 Channel-mediated Tonic GABA Release from Glia Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 20929730 Progressive NKCC1-dependent Neuronal Chloride Accumulation During Neonatal Seizures The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20810895 Synapsins Differentially Control Dopamine and Serotonin Release The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2010 | Pubmed ID: 20660258 Quantifying the Effects of Elastic Collisions and Non-covalent Binding on Glutamate Receptor Trafficking in the Post-synaptic Density PLoS Computational Biology. May, 2010 | Pubmed ID: 20485563 Transcranial Optogenetic Stimulation for Functional Mapping of the Motor Cortex Journal of Neuroscience Methods. May, 2009 | Pubmed ID: 19428535 Imaging Activity of Neuronal Populations with New Long-wavelength Voltage-sensitive Dyes Brain Cell Biology. Dec, 2008 | Pubmed ID: 19219551 Editorial: Hello, Goodbye Brain Cell Biology. Dec, 2008 | Pubmed ID: 19184439 Synapsin IIa Controls the Reserve Pool of Glutamatergic Synaptic Vesicles The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2008 | Pubmed ID: 18945891 Optogenetic Probes Brain Cell Biology. Aug, 2008 | Pubmed ID: 18941897 Improved Expression of Halorhodopsin for Light-induced Silencing of Neuronal Activity Brain Cell Biology. Aug, 2008 | Pubmed ID: 18931914 Imaging Synaptic Inhibition Throughout the Brain Via Genetically Targeted Clomeleon Brain Cell Biology. Aug, 2008 | Pubmed ID: 18850274 A Positive Feedback Signal Transduction Loop Determines Timing of Cerebellar Long-term Depression Neuron. Aug, 2008 | Pubmed ID: 18760697 Calcium Helps Neurons Identify Synaptic Targets During Development Neuron. Jul, 2008 | Pubmed ID: 18667145 Calcium Channel Modulation As an All-purpose Mechanism for Short-term Synaptic Plasticity Neuron. Jan, 2008 | Pubmed ID: 18215614 Chemical Two-photon Uncaging CSH Protocols. 2007 | Pubmed ID: 21356996 Ca2+ Requirements for Cerebellar Long-term Synaptic Depression: Role for a Postsynaptic Leaky Integrator Neuron. Jun, 2007 | Pubmed ID: 17553426 Kinetics of Complexin Binding to the SNARE Complex: Correcting Single Molecule FRET Measurements for Hidden Events Biophysical Journal. Sep, 2007 | Pubmed ID: 17513363 In Vivo Light-induced Activation of Neural Circuitry in Transgenic Mice Expressing Channelrhodopsin-2 Neuron. Apr, 2007 | Pubmed ID: 17442243 Bernard Katz, Quantal Transmitter Release and the Foundations of Presynaptic Physiology The Journal of Physiology. Feb, 2007 | Pubmed ID: 17068096 Brain Cell Technology: a Valuable New Resource for Novel Techniques Brain Cell Biology. Dec, 2006 | Pubmed ID: 18443910 Imaging Synaptic Inhibition in Transgenic Mice Expressing the Chloride Indicator, Clomeleon Brain Cell Biology. Dec, 2006 | Pubmed ID: 18398684 Synapsin II Negatively Regulates Catecholamine Release Brain Cell Biology. Jun, 2006 | Pubmed ID: 17957479 Anomalous Diffusion in Purkinje Cell Dendrites Caused by Spines Neuron. Nov, 2006 | Pubmed ID: 17114048 Cocaine Increases Dopamine Release by Mobilization of a Synapsin-dependent Reserve Pool The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16554471 The Chloride Transporter Na(+)-K(+)-Cl- Cotransporter Isoform-1 Contributes to Intracellular Chloride Increases After in Vitro Ischemia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2006 | Pubmed ID: 16452663 Two-photon Imaging Reveals Somatodendritic Chloride Gradient in Retinal ON-type Bipolar Cells Expressing the Biosensor Clomeleon Neuron. Jan, 2006 | Pubmed ID: 16387641 The Primordial, Blue-cone Color System of the Mouse Retina The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15930394 Structural Domains Involved in the Regulation of Transmitter Release by Synapsins The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15758176 Different Presynaptic Roles of Synapsins at Excitatory and Inhibitory Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2004 | Pubmed ID: 15601943 Dual Roles of the C2B Domain of Synaptotagmin I in Synchronizing Ca2+-dependent Neurotransmitter Release The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2004 | Pubmed ID: 15456828 Synaptotagmin I Synchronizes Transmitter Release in Mouse Hippocampal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2004 | Pubmed ID: 15240804 Molecular Determinants of Synapsin Targeting to Presynaptic Terminals The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2004 | Pubmed ID: 15071120 Local Calcium Signaling in Neurons Neuron. Oct, 2003 | Pubmed ID: 14556712 Eps15 Homology Domain-NPF Motif Interactions Regulate Clathrin Coat Assembly During Synaptic Vesicle Recycling The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12807910 Synaptic Vesicle Endocytosis: the Races, Places, and Molecular Faces Neuromolecular Medicine. 2002 | Pubmed ID: 12428806 Regulation of Neurotransmitter Release by Synapsin III The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2002 | Pubmed ID: 12040043 Differential Regulation of Exocytosis by Alpha- and Beta-SNAPs The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002 | Pubmed ID: 11756488 Een optogenetische Aanpak voor het beoordelen van de vorming van neuronale verbindingen in een co-cultuur systeem Colin T. E. Su*1, Su-In Yoon*2, Guillaume Marcy*1, Eunice W. M. Chin1, George J. Augustine2, Eyleen L. K. Goh1 1Neuroscience & Behavioral Disorders, Duke-NUS Graduate Medical School, 2Lee Kong Chian School of Medicine, Nanyang Technological University Biologie du développement
Een optogenetische Aanpak voor het beoordelen van de vorming van neuronale verbindingen in een co-cultuur systeem Colin T. E. Su*1, Su-In Yoon*2, Guillaume Marcy*1, Eunice W. M. Chin1, George J. Augustine2, Eyleen L. K. Goh1 1Neuroscience & Behavioral Disorders, Duke-NUS Graduate Medical School, 2Lee Kong Chian School of Medicine, Nanyang Technological University Biologie du développement